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Search results 2101 to 2200 out of 2731 for Akt1

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Type Details Score
Publication    
First Author: Kim E
Year: 2014
Journal: Elife
Title: Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1.
Volume: 3
Publication
First Author: Rakić S
Year: 2015
Journal: Cereb Cortex
Title: Cdk5 phosphorylation of ErbB4 is required for tangential migration of cortical interneurons.
Volume: 25
Issue: 4
Pages: 991-1003
Publication
First Author: Masuzaki R
Year: 2021
Journal: Am J Pathol
Title: Integrin β1 Establishes Liver Microstructure and Modulates Transforming Growth Factor β during Liver Development and Regeneration.
Volume: 191
Issue: 2
Pages: 309-319
Publication
First Author: Wang D
Year: 2013
Journal: Nat Cell Biol
Title: MicroRNA-205 controls neonatal expansion of skin stem cells by modulating the PI(3)K pathway.
Volume: 15
Issue: 10
Pages: 1153-63
Publication  
First Author: Marchant C
Year: 2020
Journal: Development
Title: Vessel-derived angiocrine IGF1 promotes Meckel's cartilage proliferation to drive jaw growth during embryogenesis.
Volume: 147
Issue: 11
Publication
First Author: Nandi S
Year: 2017
Journal: J Neurosci
Title: FGF-Dependent, Context-Driven Role for FRS Adapters in the Early Telencephalon.
Volume: 37
Issue: 23
Pages: 5690-5698
Publication
First Author: Sevilla LM
Year: 2013
Journal: J Invest Dermatol
Title: Epidermal inactivation of the glucocorticoid receptor triggers skin barrier defects and cutaneous inflammation.
Volume: 133
Issue: 2
Pages: 361-70
Publication
First Author: Schuhmacher AJ
Year: 2008
Journal: J Clin Invest
Title: A mouse model for Costello syndrome reveals an Ang II-mediated hypertensive condition.
Volume: 118
Issue: 6
Pages: 2169-79
Publication
First Author: Pan Y
Year: 2010
Journal: Development
Title: Sprouty2-modulated Kras signaling rescues Shp2 deficiency during lens and lacrimal gland development.
Volume: 137
Issue: 7
Pages: 1085-93
Publication
First Author: Chatterjee S
Year: 2016
Journal: Cell
Title: Enhancer Variants Synergistically Drive Dysfunction of a Gene Regulatory Network In Hirschsprung Disease.
Volume: 167
Issue: 2
Pages: 355-368.e10
Publication  
First Author: Rehmani T
Year: 2024
Journal: Int J Mol Sci
Title: Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3 (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of Myocardium without Affecting Hippo Pathway.
Volume: 25
Issue: 5
Publication
First Author: Yang ZF
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: GABP transcription factor is required for development of chronic myelogenous leukemia via its control of PRKD2.
Volume: 110
Issue: 6
Pages: 2312-7
Publication
First Author: Tiozzo C
Year: 2009
Journal: Am J Respir Crit Care Med
Title: Deletion of Pten expands lung epithelial progenitor pools and confers resistance to airway injury.
Volume: 180
Issue: 8
Pages: 701-12
Publication
First Author: Hoang TV
Year: 2017
Journal: Epigenetics
Title: Lens development requires DNMT1 but takes place normally in the absence of both DNMT3A and DNMT3B activity.
Volume: 12
Issue: 1
Pages: 27-40
Publication
First Author: Scott NJ
Year: 2009
Journal: Biochim Biophys Acta
Title: Influence of natriuretic peptide receptor-1 on survival and cardiac hypertrophy during development.
Volume: 1792
Issue: 12
Pages: 1175-84
Publication
First Author: Li M
Year: 2016
Journal: Stem Cell Reports
Title: EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy.
Volume: 6
Issue: 3
Pages: 396-410
Publication
First Author: Liang X
Year: 2009
Journal: Circulation
Title: Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality.
Volume: 120
Issue: 7
Pages: 568-76
Publication
First Author: Lai LP
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formation.
Volume: 110
Issue: 48
Pages: 19450-5
Publication
First Author: Wang H
Year: 2020
Journal: Cell Death Dis
Title: LIF is essential for ISC function and protects against radiation-induced gastrointestinal syndrome.
Volume: 11
Issue: 7
Pages: 588
Publication
First Author: Sathyamurthy A
Year: 2015
Journal: Development
Title: ERBB3-mediated regulation of Bergmann glia proliferation in cerebellar lamination.
Volume: 142
Issue: 3
Pages: 522-32
Publication
First Author: Hu XL
Year: 2011
Journal: Cereb Cortex
Title: Conditional deletion of NRSF in forebrain neurons accelerates epileptogenesis in the kindling model.
Volume: 21
Issue: 9
Pages: 2158-65
Publication
First Author: Lee S
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Dlg-1 Interacts With and Regulates the Activities of Fibroblast Growth Factor Receptors and EphA2 in the Mouse Lens.
Volume: 57
Issue: 2
Pages: 707-18
Publication
First Author: Cortez-Toledo O
Year: 2017
Journal: PLoS One
Title: Nur77 deletion impairs muscle growth during developmental myogenesis and muscle regeneration in mice.
Volume: 12
Issue: 2
Pages: e0171268
Publication
First Author: Zhang J
Year: 2008
Journal: Development
Title: Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis.
Volume: 135
Issue: 21
Pages: 3611-22
Publication
First Author: Tunggal JA
Year: 2005
Journal: EMBO J
Title: E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions.
Volume: 24
Issue: 6
Pages: 1146-56
Publication  
First Author: Takahara S
Year: 2019
Journal: EBioMedicine
Title: New Noonan syndrome model mice with RIT1 mutation exhibit cardiac hypertrophy and susceptibility to β-adrenergic stimulation-induced cardiac fibrosis.
Volume: 42
Pages: 43-53
Publication
First Author: Jia WJ
Year: 2016
Journal: Am J Pathol
Title: Geranylgeranyl Diphosphate Synthase Modulates Fetal Lung Branching Morphogenesis Possibly through Controlling K-Ras Prenylation.
Volume: 186
Issue: 6
Pages: 1454-65
Publication
First Author: Ma A
Year: 2014
Journal: Hum Mol Genet
Title: Tsc1 deficiency-mediated mTOR hyperactivation in vascular endothelial cells causes angiogenesis defects and embryonic lethality.
Volume: 23
Issue: 3
Pages: 693-705
Publication
First Author: Morioka T
Year: 2014
Journal: Genesis
Title: An important role of endothelial hairy-related transcription factors in mouse vascular development.
Volume: 52
Issue: 11
Pages: 897-906
Publication
First Author: Ichikawa-Tomikawa N
Year: 2012
Journal: Matrix Biol
Title: Laminin α1 is essential for mouse cerebellar development.
Volume: 31
Issue: 1
Pages: 17-28
Publication
First Author: Stenvers KL
Year: 2003
Journal: Mol Cell Biol
Title: Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos.
Volume: 23
Issue: 12
Pages: 4371-85
Publication
First Author: Smeeton J
Year: 2010
Journal: Development
Title: Integrin-linked kinase regulates p38 MAPK-dependent cell cycle arrest in ureteric bud development.
Volume: 137
Issue: 19
Pages: 3233-43
Publication
First Author: Wei Y
Year: 2020
Journal: Mol Brain
Title: PDK1 regulates the survival of the developing cortical interneurons.
Volume: 13
Issue: 1
Pages: 65
Publication
First Author: Xu M
Year: 2019
Journal: Cereb Cortex
Title: PDK1 Deficit Impairs the Development of the Dentate Gyrus in Mice.
Volume: 29
Issue: 3
Pages: 1185-1198
Publication
First Author: Umans L
Year: 2003
Journal: Genesis
Title: Generation of a floxed allele of Smad5 for cre-mediated conditional knockout in the mouse.
Volume: 37
Issue: 1
Pages: 5-11
Publication
First Author: Chaffee BR
Year: 2016
Journal: Dev Biol
Title: FGFR and PTEN signaling interact during lens development to regulate cell survival.
Volume: 410
Issue: 2
Pages: 150-163
Publication
First Author: Madakashira BP
Year: 2012
Journal: Development
Title: Frs2α enhances fibroblast growth factor-mediated survival and differentiation in lens development.
Volume: 139
Issue: 24
Pages: 4601-12
Publication  
First Author: Landin Malt A
Year: 2020
Journal: J Cell Biol
Title: Wnts regulate planar cell polarity via heterotrimeric G protein and PI3K signaling.
Volume: 219
Issue: 10
Publication
First Author: Holmes G
Year: 2009
Journal: Dev Biol
Title: Early onset of craniosynostosis in an Apert mouse model reveals critical features of this pathology.
Volume: 328
Issue: 2
Pages: 273-84
Publication
First Author: Mori M
Year: 2011
Journal: J Clin Invest
Title: Death effector domain-containing protein (DEDD) is required for uterine decidualization during early pregnancy in mice.
Volume: 121
Issue: 1
Pages: 318-27
Publication  
First Author: Ju H
Year: 2024
Journal: Biochem Biophys Res Commun
Title: Gestational diabetes mellitus induces congenital anomalies of the kidney and urinary tract in mice by altering RET/MAPK/ERK pathway.
Volume: 714
Pages: 149959
Publication
First Author: Chen H
Year: 2023
Journal: Blood
Title: PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371.
Volume: 141
Issue: 3
Pages: 244-259
Publication  
First Author: Tidyman WE
Year: 2022
Journal: Dis Model Mech
Title: MEK-inhibitor-mediated rescue of skeletal myopathy caused by activating Hras mutation in a Costello syndrome mouse model.
Volume: 15
Issue: 2
Publication
First Author: Tan Y
Year: 2010
Journal: Genesis
Title: Appl1 is dispensable for Akt signaling in vivo and mouse T-cell development.
Volume: 48
Issue: 9
Pages: 531-9
Publication
First Author: Dong Y
Year: 2012
Journal: J Biol Chem
Title: Phosphatase of regenerating liver 2 (PRL2) is essential for placental development by down-regulating PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) and activating Akt protein.
Volume: 287
Issue: 38
Pages: 32172-9
Publication
First Author: Rashidieh B
Year: 2021
Journal: PLoS Genet
Title: Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis.
Volume: 17
Issue: 10
Pages: e1009334
Publication
First Author: Lee H
Year: 2019
Journal: Transl Psychiatry
Title: Constitutional mislocalization of Pten drives precocious maturation in oligodendrocytes and aberrant myelination in model of autism spectrum disorder.
Volume: 9
Issue: 1
Pages: 13
Publication
First Author: Qiu X
Year: 2016
Journal: Oncotarget
Title: NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner.
Volume: 7
Issue: 21
Pages: 31440-53
Publication
First Author: Navas-Pérez E
Year: 2020
Journal: Genome Biol
Title: Characterization of an eutherian gene cluster generated after transposon domestication identifies Bex3 as relevant for advanced neurological functions.
Volume: 21
Issue: 1
Pages: 267
Publication
First Author: Koyama N
Year: 2003
Journal: Dev Dyn
Title: EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland.
Volume: 227
Issue: 2
Pages: 216-26
Publication
First Author: Hoxhaj G
Year: 2012
Journal: J Cell Sci
Title: ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase.
Volume: 125
Issue: Pt 19
Pages: 4662-75
Publication
First Author: Liu J
Year: 2004
Journal: Reproduction
Title: Serine-threonine kinases and transcription factors active in signal transduction are detected at high levels of phosphorylation during mitosis in preimplantation embryos and trophoblast stem cells.
Volume: 128
Issue: 5
Pages: 643-54
Publication
First Author: Rokutanda S
Year: 2009
Journal: Dev Biol
Title: Akt regulates skeletal development through GSK3, mTOR, and FoxOs.
Volume: 328
Issue: 1
Pages: 78-93
Publication
First Author: Yamauchi J
Year: 2011
Journal: J Neurosci
Title: The atypical Guanine-nucleotide exchange factor, dock7, negatively regulates schwann cell differentiation and myelination.
Volume: 31
Issue: 35
Pages: 12579-92
Publication
First Author: Mavila N
Year: 2012
Journal: PLoS One
Title: Fibroblast growth factor receptor-mediated activation of AKT-β-catenin-CBP pathway regulates survival and proliferation of murine hepatoblasts and hepatic tumor initiating stem cells.
Volume: 7
Issue: 11
Pages: e50401
Publication
First Author: Chen Q
Year: 2015
Journal: FASEB J
Title: Mesenchyme-specific overexpression of nucleolar protein 66 in mice inhibits skeletal growth and bone formation.
Volume: 29
Issue: 6
Pages: 2555-65
Publication
First Author: Dharaneeswaran H
Year: 2014
Journal: Circ Res
Title: FOXO1-mediated activation of Akt plays a critical role in vascular homeostasis.
Volume: 115
Issue: 2
Pages: 238-251
Publication  
First Author: Hu Q
Year: 2012
Journal: ASN Neuro
Title: Signalling through the type 1 insulin-like growth factor receptor (IGF1R) interacts with canonical Wnt signalling to promote neural proliferation in developing brain.
Volume: 4
Issue: 5
Publication
First Author: Wang S
Year: 2022
Journal: Dev Cell
Title: KIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice.
Volume: 57
Issue: 19
Pages: 2273-2289.e11
Publication
First Author: Lai Y
Year: 2023
Journal: Sci Rep
Title: Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development.
Volume: 13
Issue: 1
Pages: 15170
Publication  
First Author: Basu S
Year: 2024
Journal: Cereb Cortex
Title: Identification of Pappa and Sall3 as Gli3 direct target genes acting downstream of cilia signaling in corticogenesis.
Volume: 34
Issue: 12
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication
First Author: Yokoyama K
Year: 2011
Journal: EMBO J
Title: NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons.
Volume: 30
Issue: 23
Pages: 4739-54
Publication
First Author: He Y
Year: 2010
Journal: Sci Signal
Title: Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development.
Volume: 3
Issue: 116
Pages: ra26
Publication
First Author: Di Cunto F
Year: 2000
Journal: Neuron
Title: Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis.
Volume: 28
Issue: 1
Pages: 115-27
Publication
First Author: Wakabayashi Y
Year: 2003
Journal: Nat Immunol
Title: Bcl11b is required for differentiation and survival of alphabeta T lymphocytes.
Volume: 4
Issue: 6
Pages: 533-9
Publication
First Author: Ajima R
Year: 2015
Journal: Dev Biol
Title: DAAM1 and DAAM2 are co-required for myocardial maturation and sarcomere assembly.
Volume: 408
Issue: 1
Pages: 126-39
Publication
First Author: Krentz AD
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency.
Volume: 106
Issue: 52
Pages: 22323-8
Publication
First Author: Ikegami D
Year: 2011
Journal: Development
Title: Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways.
Volume: 138
Issue: 8
Pages: 1507-19
Publication
First Author: Zhou T
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Palmitoyl acyltransferase Aph2 in cardiac function and the development of cardiomyopathy.
Volume: 112
Issue: 51
Pages: 15666-71
Publication
First Author: Kechele DO
Year: 2017
Journal: J Clin Invest
Title: Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation.
Volume: 127
Issue: 2
Pages: 593-607
Publication  
First Author: Kvajo M
Year: 2012
Journal: Neuroscience
Title: Avoiding mouse traps in schizophrenia genetics: lessons and promises from current and emerging mouse models.
Volume: 211
Pages: 136-64
Publication
First Author: Sugiyama N
Year: 2011
Journal: Kidney Int
Title: The canonical Wnt signaling pathway is not involved in renal cyst development in the kidneys of inv mutant mice.
Volume: 79
Issue: 9
Pages: 957-65
Publication  
First Author: Alavian KN
Year: 2009
Journal: Neural Dev
Title: Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression.
Volume: 4
Pages: 11
Publication
First Author: Wang H
Year: 2007
Journal: J Biol Chem
Title: Stage-specific integration of maternal and embryonic peroxisome proliferator-activated receptor delta signaling is critical to pregnancy success.
Volume: 282
Issue: 52
Pages: 37770-82
Publication
First Author: Hippenmeyer S
Year: 2005
Journal: PLoS Biol
Title: A developmental switch in the response of DRG neurons to ETS transcription factor signaling.
Volume: 3
Issue: 5
Pages: e159
Publication
First Author: O'Donovan KJ
Year: 2014
Journal: J Exp Med
Title: B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS.
Volume: 211
Issue: 5
Pages: 801-14
Publication
First Author: Xu J
Year: 2012
Journal: PLoS One
Title: Fstl1 antagonizes BMP signaling and regulates ureter development.
Volume: 7
Issue: 4
Pages: e32554
Publication
First Author: Zhong J
Year: 2007
Journal: Nat Neurosci
Title: Raf kinase signaling functions in sensory neuron differentiation and axon growth in vivo.
Volume: 10
Issue: 5
Pages: 598-607
Publication
First Author: Inoue S
Year: 2014
Journal: Hum Mol Genet
Title: New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome.
Volume: 23
Issue: 24
Pages: 6553-66
Publication
First Author: Li C
Year: 2013
Journal: Dev Biol
Title: Apc deficiency alters pulmonary epithelial cell fate and inhibits Nkx2.1 via triggering TGF-beta signaling.
Volume: 378
Issue: 1
Pages: 13-24
Publication  
First Author: Yiu JHC
Year: 2021
Journal: Front Cell Dev Biol
Title: TLR5 Supports Development of Placental Labyrinthine Zone in Mice.
Volume: 9
Pages: 711253
Publication
First Author: Fan Y
Year: 2015
Journal: PLoS Genet
Title: Tissue-Specific Gain of RTK Signalling Uncovers Selective Cell Vulnerability during Embryogenesis.
Volume: 11
Issue: 9
Pages: e1005533
Publication
First Author: Le D
Year: 2021
Journal: Mol Cells
Title: Tsg101 Is Necessary for the Establishment and Maintenance of Mouse Retinal Pigment Epithelial Cell Polarity.
Volume: 44
Issue: 3
Pages: 168-178
Publication
First Author: Gong X
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Expression of ILK in renal stroma is essential for multiple aspects of renal development.
Volume: 315
Issue: 2
Pages: F374-F385
Publication
First Author: Jo HS
Year: 2012
Journal: EMBO J
Title: Pten coordinates retinal neurogenesis by regulating Notch signalling.
Volume: 31
Issue: 4
Pages: 817-28
Publication
First Author: Hare LM
Year: 2015
Journal: Dev Biol
Title: Heterozygous expression of the oncogenic Pik3ca(H1047R) mutation during murine development results in fatal embryonic and extraembryonic defects.
Volume: 404
Issue: 1
Pages: 14-26
Publication
First Author: Duan X
Year: 2015
Journal: Development
Title: Vegfa regulates perichondrial vascularity and osteoblast differentiation in bone development.
Volume: 142
Issue: 11
Pages: 1984-91
Publication
First Author: Pais RS
Year: 2013
Journal: PLoS One
Title: Transcriptome analysis in prenatal IGF1-deficient mice identifies molecular pathways and target genes involved in distal lung differentiation.
Volume: 8
Issue: 12
Pages: e83028
Publication
First Author: Win PW
Year: 2020
Journal: Cell Tissue Res
Title: Beta-cell β1 integrin deficiency affects in utero development of islet growth and vascularization.
Volume: 381
Issue: 1
Pages: 163-175
Publication
First Author: Wang Y
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: β1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis.
Volume: 58
Issue: 10
Pages: 3896-3922
Publication
First Author: Pathania M
Year: 2016
Journal: Differentiation
Title: β1-integrin controls cell fate specification in early lens development.
Volume: 92
Issue: 4
Pages: 133-147
Publication
First Author: Cinque L
Year: 2015
Journal: Nature
Title: FGF signalling regulates bone growth through autophagy.
Volume: 528
Issue: 7581
Pages: 272-5
Publication
First Author: Ritié L
Year: 2012
Journal: PLoS One
Title: Abnormal Wnt and PI3Kinase signaling in the malformed intestine of lama5 deficient mice.
Volume: 7
Issue: 5
Pages: e37710
Publication
First Author: Chen X
Year: 2010
Journal: Mol Endocrinol
Title: The cooperative function of nuclear receptor coactivator 1 (NCOA1) and NCOA3 in placental development and embryo survival.
Volume: 24
Issue: 10
Pages: 1917-34
Publication
First Author: Li Z
Year: 2014
Journal: J Cell Sci
Title: Synemin acts as a regulator of signalling molecules during skeletal muscle hypertrophy.
Volume: 127
Issue: Pt 21
Pages: 4589-601
Publication
First Author: Zhuang L
Year: 2018
Journal: Nat Commun
Title: Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function.
Volume: 9
Issue: 1
Pages: 1796
Publication
First Author: Shin JY
Year: 2017
Journal: Hum Mol Genet
Title: Lamina-associated polypeptide 1 is dispensable for embryonic myogenesis but required for postnatal skeletal muscle growth.
Volume: 26
Issue: 1
Pages: 65-78
Publication
First Author: Lauriol J
Year: 2016
Journal: J Clin Invest
Title: Developmental SHP2 dysfunction underlies cardiac hypertrophy in Noonan syndrome with multiple lentigines.
Volume: 126
Issue: 8
Pages: 2989-3005
Publication
First Author: Chen PC
Year: 2010
Journal: J Clin Invest
Title: Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome–associated Sos1 mutation.
Volume: 120
Issue: 12
Pages: 4353-65