|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 2101 to 2200 out of 2657 for Igf2

0.024s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication
First Author: Pravtcheva DD
Year: 2008
Journal: Mol Reprod Dev
Title: Igf2r improves the survival and transmission ratio of Igf2 transgenic mice.
Volume: 75
Issue: 11
Pages: 1678-87
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Srivastava M
Year: 2000
Journal: Genes Dev
Title: H19 and Igf2 monoallelic expression is regulated in two distinct ways by a shared cis acting regulatory region upstream of H19.
Volume: 14
Issue: 10
Pages: 1186-95
Publication
First Author: Ainscough JF
Year: 2000
Journal: Development
Title: A skeletal muscle-specific mouse Igf2 repressor lies 40 kb downstream of the gene.
Volume: 127
Issue: 18
Pages: 3923-30
Publication
First Author: Ainscough JF
Year: 1997
Journal: Development
Title: Imprinting of Igf2 and H19 from a 130 kb YAC transgene.
Volume: 124
Issue: 18
Pages: 3621-32
Publication    
First Author: Dai N
Year: 2017
Journal: Elife
Title: IGF2 mRNA binding protein-2 is a tumor promoter that drives cancer proliferation through its client mRNAs IGF2 and HMGA1.
Volume: 6
Publication
First Author: Verona RI
Year: 2004
Journal: Genomics
Title: Role of H19 3' sequences in controlling H19 and Igf2 imprinting and expression.
Volume: 84
Issue: 1
Pages: 59-68
Allele  
Name: minute imprinted gene in the Igf2 region; wild type
Allele Type: Not Specified
Publication
First Author: Dai N
Year: 2011
Journal: Genes Dev
Title: mTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry.
Volume: 25
Issue: 11
Pages: 1159-72
Regulatory Region
Type: promoter
Organism: mouse, laboratory
Regulatory Region
Type: promoter
Organism: mouse, laboratory
Regulatory Region
Type: promoter
Organism: mouse, laboratory
Publication
First Author: Pardo M
Year: 2017
Journal: JCI Insight
Title: Intranasal siRNA administration reveals IGF2 deficiency contributes to impaired cognition in Fragile X syndrome mice.
Volume: 2
Issue: 6
Pages: e91782
Publication
First Author: Raudsepp T
Year: 1997
Journal: Mamm Genome
Title: FISH mapping of the IGF2 gene in horse and donkey-detection of homoeology with HSA11.
Volume: 8
Issue: 8
Pages: 569-72
Publication
First Author: Lovett FA
Year: 2010
Journal: Endocrinology
Title: Essential role for p38alpha MAPK but not p38gamma MAPK in Igf2 expression and myoblast differentiation.
Volume: 151
Issue: 9
Pages: 4368-80
Publication
First Author: Jouvenot Y
Year: 1999
Journal: Curr Biol
Title: Biallelic transcription of Igf2 and H19 in individual cells suggests a post-transcriptional contribution to genomic imprinting.
Volume: 9
Issue: 20
Pages: 1199-202
Publication
First Author: Harris TM
Year: 1998
Journal: Oncogene
Title: Reactivation of the maternally imprinted IGF2 allele in TGFalpha induced hepatocellular carcinomas in mice.
Volume: 16
Issue: 2
Pages: 203-9
Publication
First Author: Otte K
Year: 1998
Journal: Nucleic Acids Res
Title: A conserved structural element in horse and mouse IGF2 genes binds a methylation sensitive factor.
Volume: 26
Issue: 7
Pages: 1605-12
Publication
First Author: Kessler SM
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: IGF2 mRNA binding protein p62/IMP2-2 in hepatocellular carcinoma: antiapoptotic action is independent of IGF2/PI3K signaling.
Volume: 304
Issue: 4
Pages: G328-36
Publication
First Author: Laggai S
Year: 2014
Journal: J Lipid Res
Title: The IGF2 mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis.
Volume: 55
Issue: 6
Pages: 1087-97
Publication
First Author: Liu H
Year: 2018
Journal: Histochem Cell Biol
Title: Histochemical evidence of IGF2 mRNA-binding protein 2-mediated regulation of osteoclast function and adhesive ability.
Volume: 149
Issue: 4
Pages: 343-351
Publication
First Author: Lovett FA
Year: 2006
Journal: J Cell Sci
Title: Convergence of Igf2 expression and adhesion signalling via RhoA and p38 MAPK enhances myogenic differentiation.
Volume: 119
Issue: Pt 23
Pages: 4828-40
Publication
First Author: Tran VG
Year: 2012
Journal: PLoS One
Title: H19 antisense RNA can up-regulate Igf2 transcription by activation of a novel promoter in mouse myoblasts.
Volume: 7
Issue: 5
Pages: e37923
Publication
First Author: Alders M
Year: 1997
Journal: Hum Mol Genet
Title: The human Achaete-Scute homologue 2 (ASCL2,HASH2) maps to chromosome 11p15.5, close to IGF2 and is expressed in extravillus trophoblasts.
Volume: 6
Issue: 6
Pages: 859-67
Genotype
Symbol: Minute/Minute<+>
Background: involves: 101/H * C3H/HeH * C57BL/6J * CBA/Ca * M. spretus
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Minute/Minute<+>
Background: involves: 101/H * C3H/HeH
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Minute/Minute<+>
Background: involves: 101/H * C3H/HeH * M. m. castaneus
Zygosity: ht
Has Mutant Allele: true
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Okutsu T
Year: 2000
Journal: J Biochem
Title: Expression and imprinting status of human PEG8/IGF2AS, a paternally expressed antisense transcript from the IGF2 locus, in Wilms' tumors.
Volume: 127
Issue: 3
Pages: 475-83
Publication
First Author: Zaina S
Year: 2003
Journal: Endocrinology
Title: Shortened life span, bradycardia, and hypotension in mice with targeted expression of an Igf2 transgene in smooth muscle cells.
Volume: 144
Issue: 6
Pages: 2695-703
Publication
First Author: Schmutz SM
Year: 1996
Journal: Mamm Genome
Title: In situ hybridization mapping of LDHA and IGF2 to cattle chromosome 29.
Volume: 7
Issue: 6
Pages: 473
Publication
First Author: Frago S
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist.
Volume: 113
Issue: 20
Pages: E2766-75
Publication
First Author: Boo HJ
Year: 2023
Journal: Cancer Res
Title: Dual Impact of IGF2 on Alveolar Stem Cell Function during Tobacco-Induced Injury Repair and Development of Pulmonary Emphysema and Cancer.
Volume: 83
Issue: 11
Pages: 1782-1799
Publication
First Author: Markljung E
Year: 2009
Journal: PLoS Biol
Title: ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth.
Volume: 7
Issue: 12
Pages: e1000256
Publication
First Author: Haddad R
Year: 1997
Journal: Cancer Res
Title: Genomic imprinting and Igf2 influence liver tumorigenesis and loss of heterozygosity in SV40 T antigen transgenic mice.
Volume: 57
Issue: 20
Pages: 4615-23
Publication
First Author: Jang HJ
Year: 2016
Journal: Cancer Res
Title: Chronic Stress Facilitates Lung Tumorigenesis by Promoting Exocytosis of IGF2 in Lung Epithelial Cells.
Volume: 76
Issue: 22
Pages: 6607-6619
Publication
First Author: Reed MR
Year: 2001
Journal: Mamm Genome
Title: Deletion of a direct repeat element has no effect on Igf2 and H19 imprinting.
Volume: 12
Issue: 11
Pages: 873-6
Publication
First Author: Shahmoradi A
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Enhanced memory consolidation in mice lacking the circadian modulators Sharp1 and -2 caused by elevated Igf2 signaling in the cortex.
Volume: 112
Issue: 27
Pages: E3582-9
Publication
First Author: Zhu CQ
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Integrin alpha 11 regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells.
Volume: 104
Issue: 28
Pages: 11754-9
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 9.5
Stage: 15
Structure . Name: embryo
Notes: The Igf2 allele was inherited from the father.
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 9.5
Stage: 15
Structure . Name: embryo
Notes: The Igf2 allele was inherited from the father.
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 9.5
Stage: 15
Structure . Name: embryo
Notes: The Igf2 allele was inherited from the father.
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 9.5
Stage: 15
Structure . Name: embryo
Notes: The Igf2 allele was inherited from the father.
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 9.5
Stage: 15
Structure . Name: embryo
Notes: The Igf2 allele was inherited from the father.
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 9.5
Stage: 15
Structure . Name: embryo
Notes: The Igf2 allele was inherited from the father.
Curation Status: Curated
Publication
First Author: Reed MR
Year: 2001
Journal: Genomics
Title: A complex duplication created by gene targeting at the imprinted H19 locus results in two classes of methylation and correlated Igf2 expression phenotypes.
Volume: 74
Issue: 2
Pages: 186-96
Publication
First Author: Regué L
Year: 2019
Journal: J Biol Chem
Title: Liver-specific deletion of IGF2 mRNA binding protein-2/IMP2 reduces hepatic fatty acid oxidation and increases hepatic triglyceride accumulation.
Volume: 294
Issue: 31
Pages: 11944-11951
Publication
First Author: Mellott TJ
Year: 2014
Journal: PLoS One
Title: IGF2 ameliorates amyloidosis, increases cholinergic marker expression and raises BMP9 and neurotrophin levels in the hippocampus of the APPswePS1dE9 Alzheimer's disease model mice.
Volume: 9
Issue: 4
Pages: e94287
Publication
First Author: Kaneda A
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk.
Volume: 104
Issue: 52
Pages: 20926-31
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
Protein
Organism: Mus musculus/domesticus
Length: 579  
Fragment?: false
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 9.5
Stage: 15
Structure . Name: embryo
Notes: The Igf2 allele was inherited from the father; he was Igf2+/-;Trp53+/-.
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 9.5
Stage: 15
Structure . Name: embryo
Notes: The Igf2 allele was inherited from the father; he was Igf2+/-;Trp53+/-.
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 9.5
Stage: 15
Structure . Name: embryo
Notes: The Igf2 allele was inherited from the father; he was Igf2+/-;Trp53+/-.
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 9.5
Stage: 15
Structure . Name: embryo
Notes: The Igf2 allele was inherited from the father; like his offspring, he was Igf2+/-;Trp53+/-.
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 9.5
Stage: 15
Structure . Name: embryo
Notes: The Igf2 allele was inherited from the father; like his offspring, he was Igf2+/-;Trp53+/-.
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 9.5
Stage: 15
Structure . Name: embryo
Notes: The Igf2 allele was inherited from the father; like his offspring, he was Igf2+/-;Trp53+/-.
Curation Status: Curated
Protein
Organism: Mus musculus/domesticus
Length: 592  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 530  
Fragment?: false
HT Sample
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal day 120
Stage: 28
Structure . Name: small intestine crypt of lieberkuhn
Notes: this animal has not experienced loss of imprinting; it could be carrying a maternal Igf2 allele, which has been silenced
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal day 120
Stage: 28
Structure . Name: small intestine crypt of lieberkuhn
Notes: this animal has not experienced loss of imprinting; it could be carrying a maternal Igf2 allele, which has been silenced
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal day 120
Stage: 28
Structure . Name: small intestine crypt of lieberkuhn
Notes: this animal has not experienced loss of imprinting; it could be carrying a maternal Igf2 allele, which has been silenced
Curation Status: Curated
Regulatory Region
Type: silencer
Organism: mouse, laboratory
Allele
Name: regulatory region 28; targeted mutation 1, Shirley M Tilghman
Allele Type: Targeted
Attribute String: Modified regulatory region, Null/knockout
Protein
Organism: Mus musculus/domesticus
Length: 577  
Fragment?: false
HT Experiment
Series Id: GSE8583
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Mori H
Year: 2001
Journal: J Neurosci Res
Title: Expression of mouse igf2 mRNA-binding protein 3 and its implications for the developing central nervous system.
Volume: 64
Issue: 2
Pages: 132-43
Publication
First Author: Pant V
Year: 2003
Journal: Genes Dev
Title: The nucleotides responsible for the direct physical contact between the chromatin insulator protein CTCF and the H19 imprinting control region manifest parent of origin-specific long-distance insulation and methylation-free domains.
Volume: 17
Issue: 5
Pages: 586-90
Publication
First Author: Liao J
Year: 2023
Journal: Sci Adv
Title: Establishment of paternal methylation imprint at the H19/Igf2 imprinting control region.
Volume: 9
Issue: 36
Pages: eadi2050
Publication      
First Author: Park K-S
Year: 2021
Journal: bioRxiv
Title: Cardiac pathologies in mouse loss of imprinting models are due to misexpression of H19 long noncoding RNA.
Publication    
First Author: Park KS
Year: 2021
Journal: Elife
Title: Cardiac pathologies in mouse loss of imprinting models are due to misexpression of H19 long noncoding RNA.
Volume: 10
Publication  
First Author: Regué L
Year: 2019
Journal: Mol Cell Biol
Title: IMP2 Increases Mouse Skeletal Muscle Mass and Voluntary Activity by Enhancing Autocrine Insulin-Like Growth Factor 2 Production and Optimizing Muscle Metabolism.
Volume: 39
Issue: 7
Allele
Name: transgene insertion Laura, Christopher F Graham
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion Leroy, Christopher F Graham
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion Lesley, Christopher F Graham
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion Lorna, Christopher F Graham
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Vernucci M
Year: 2004
Journal: Hum Mol Genet
Title: Developmentally regulated functions of the H19 differentially methylated domain.
Volume: 13
Issue: 3
Pages: 353-61