| Type |
Details |
Score |
| Publication |
| First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
| Year: |
2004 |
| Journal: |
Database Release |
| Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shanghai Model Organisms Center |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2014 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Magdaleno S |
| Year: |
2006 |
| Journal: |
PLoS Biol |
| Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
| Volume: |
4 |
| Issue: |
4 |
| Pages: |
e86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Skarnes WC |
| Year: |
2011 |
| Journal: |
Nature |
| Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
| Volume: |
474 |
| Issue: |
7351 |
| Pages: |
337-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pravtcheva DD |
| Year: |
2008 |
| Journal: |
Mol Reprod Dev |
| Title: |
Igf2r improves the survival and transmission ratio of Igf2 transgenic mice. |
| Volume: |
75 |
| Issue: |
11 |
| Pages: |
1678-87 |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Srivastava M |
| Year: |
2000 |
| Journal: |
Genes Dev |
| Title: |
H19 and Igf2 monoallelic expression is regulated in two distinct ways by a shared cis acting regulatory region upstream of H19. |
| Volume: |
14 |
| Issue: |
10 |
| Pages: |
1186-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ainscough JF |
| Year: |
2000 |
| Journal: |
Development |
| Title: |
A skeletal muscle-specific mouse Igf2 repressor lies 40 kb downstream of the gene. |
| Volume: |
127 |
| Issue: |
18 |
| Pages: |
3923-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ainscough JF |
| Year: |
1997 |
| Journal: |
Development |
| Title: |
Imprinting of Igf2 and H19 from a 130 kb YAC transgene. |
| Volume: |
124 |
| Issue: |
18 |
| Pages: |
3621-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dai N |
| Year: |
2017 |
| Journal: |
Elife |
| Title: |
IGF2 mRNA binding protein-2 is a tumor promoter that drives cancer proliferation through its client mRNAs IGF2 and HMGA1. |
| Volume: |
6 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Verona RI |
| Year: |
2004 |
| Journal: |
Genomics |
| Title: |
Role of H19 3' sequences in controlling H19 and Igf2 imprinting and expression. |
| Volume: |
84 |
| Issue: |
1 |
| Pages: |
59-68 |
|
•
•
•
•
•
|
| Allele |
| Name: |
minute imprinted gene in the Igf2 region; wild type |
| Allele Type: |
Not Specified |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dai N |
| Year: |
2011 |
| Journal: |
Genes Dev |
| Title: |
mTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry. |
| Volume: |
25 |
| Issue: |
11 |
| Pages: |
1159-72 |
|
•
•
•
•
•
|
| Regulatory Region |
| Type: |
promoter |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Regulatory Region |
| Type: |
promoter |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Regulatory Region |
| Type: |
promoter |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pardo M |
| Year: |
2017 |
| Journal: |
JCI Insight |
| Title: |
Intranasal siRNA administration reveals IGF2 deficiency contributes to impaired cognition in Fragile X syndrome mice. |
| Volume: |
2 |
| Issue: |
6 |
| Pages: |
e91782 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Raudsepp T |
| Year: |
1997 |
| Journal: |
Mamm Genome |
| Title: |
FISH mapping of the IGF2 gene in horse and donkey-detection of homoeology with HSA11. |
| Volume: |
8 |
| Issue: |
8 |
| Pages: |
569-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lovett FA |
| Year: |
2010 |
| Journal: |
Endocrinology |
| Title: |
Essential role for p38alpha MAPK but not p38gamma MAPK in Igf2 expression and myoblast differentiation. |
| Volume: |
151 |
| Issue: |
9 |
| Pages: |
4368-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jouvenot Y |
| Year: |
1999 |
| Journal: |
Curr Biol |
| Title: |
Biallelic transcription of Igf2 and H19 in individual cells suggests a post-transcriptional contribution to genomic imprinting. |
| Volume: |
9 |
| Issue: |
20 |
| Pages: |
1199-202 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Harris TM |
| Year: |
1998 |
| Journal: |
Oncogene |
| Title: |
Reactivation of the maternally imprinted IGF2 allele in TGFalpha induced hepatocellular carcinomas in mice. |
| Volume: |
16 |
| Issue: |
2 |
| Pages: |
203-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Otte K |
| Year: |
1998 |
| Journal: |
Nucleic Acids Res |
| Title: |
A conserved structural element in horse and mouse IGF2 genes binds a methylation sensitive factor. |
| Volume: |
26 |
| Issue: |
7 |
| Pages: |
1605-12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kessler SM |
| Year: |
2013 |
| Journal: |
Am J Physiol Gastrointest Liver Physiol |
| Title: |
IGF2 mRNA binding protein p62/IMP2-2 in hepatocellular carcinoma: antiapoptotic action is independent of IGF2/PI3K signaling. |
| Volume: |
304 |
| Issue: |
4 |
| Pages: |
G328-36 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Laggai S |
| Year: |
2014 |
| Journal: |
J Lipid Res |
| Title: |
The IGF2 mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis. |
| Volume: |
55 |
| Issue: |
6 |
| Pages: |
1087-97 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu H |
| Year: |
2018 |
| Journal: |
Histochem Cell Biol |
| Title: |
Histochemical evidence of IGF2 mRNA-binding protein 2-mediated regulation of osteoclast function and adhesive ability. |
| Volume: |
149 |
| Issue: |
4 |
| Pages: |
343-351 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lovett FA |
| Year: |
2006 |
| Journal: |
J Cell Sci |
| Title: |
Convergence of Igf2 expression and adhesion signalling via RhoA and p38 MAPK enhances myogenic differentiation. |
| Volume: |
119 |
| Issue: |
Pt 23 |
| Pages: |
4828-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tran VG |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
H19 antisense RNA can up-regulate Igf2 transcription by activation of a novel promoter in mouse myoblasts. |
| Volume: |
7 |
| Issue: |
5 |
| Pages: |
e37923 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Alders M |
| Year: |
1997 |
| Journal: |
Hum Mol Genet |
| Title: |
The human Achaete-Scute homologue 2 (ASCL2,HASH2) maps to chromosome 11p15.5, close to IGF2 and is expressed in extravillus trophoblasts. |
| Volume: |
6 |
| Issue: |
6 |
| Pages: |
859-67 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Minute/Minute<+> |
| Background: |
involves: 101/H * C3H/HeH * C57BL/6J * CBA/Ca * M. spretus |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Minute/Minute<+> |
| Background: |
involves: 101/H * C3H/HeH |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Minute/Minute<+> |
| Background: |
involves: 101/H * C3H/HeH * M. m. castaneus |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okutsu T |
| Year: |
2000 |
| Journal: |
J Biochem |
| Title: |
Expression and imprinting status of human PEG8/IGF2AS, a paternally expressed antisense transcript from the IGF2 locus, in Wilms' tumors. |
| Volume: |
127 |
| Issue: |
3 |
| Pages: |
475-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zaina S |
| Year: |
2003 |
| Journal: |
Endocrinology |
| Title: |
Shortened life span, bradycardia, and hypotension in mice with targeted expression of an Igf2 transgene in smooth muscle cells. |
| Volume: |
144 |
| Issue: |
6 |
| Pages: |
2695-703 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schmutz SM |
| Year: |
1996 |
| Journal: |
Mamm Genome |
| Title: |
In situ hybridization mapping of LDHA and IGF2 to cattle chromosome 29. |
| Volume: |
7 |
| Issue: |
6 |
| Pages: |
473 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Frago S |
| Year: |
2016 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist. |
| Volume: |
113 |
| Issue: |
20 |
| Pages: |
E2766-75 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Boo HJ |
| Year: |
2023 |
| Journal: |
Cancer Res |
| Title: |
Dual Impact of IGF2 on Alveolar Stem Cell Function during Tobacco-Induced Injury Repair and Development of Pulmonary Emphysema and Cancer. |
| Volume: |
83 |
| Issue: |
11 |
| Pages: |
1782-1799 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Markljung E |
| Year: |
2009 |
| Journal: |
PLoS Biol |
| Title: |
ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth. |
| Volume: |
7 |
| Issue: |
12 |
| Pages: |
e1000256 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Haddad R |
| Year: |
1997 |
| Journal: |
Cancer Res |
| Title: |
Genomic imprinting and Igf2 influence liver tumorigenesis and loss of heterozygosity in SV40 T antigen transgenic mice. |
| Volume: |
57 |
| Issue: |
20 |
| Pages: |
4615-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jang HJ |
| Year: |
2016 |
| Journal: |
Cancer Res |
| Title: |
Chronic Stress Facilitates Lung Tumorigenesis by Promoting Exocytosis of IGF2 in Lung Epithelial Cells. |
| Volume: |
76 |
| Issue: |
22 |
| Pages: |
6607-6619 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Reed MR |
| Year: |
2001 |
| Journal: |
Mamm Genome |
| Title: |
Deletion of a direct repeat element has no effect on Igf2 and H19 imprinting. |
| Volume: |
12 |
| Issue: |
11 |
| Pages: |
873-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shahmoradi A |
| Year: |
2015 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Enhanced memory consolidation in mice lacking the circadian modulators Sharp1 and -2 caused by elevated Igf2 signaling in the cortex. |
| Volume: |
112 |
| Issue: |
27 |
| Pages: |
E3582-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhu CQ |
| Year: |
2007 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Integrin alpha 11 regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells. |
| Volume: |
104 |
| Issue: |
28 |
| Pages: |
11754-9 |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 9.5 |
| Stage: |
15 |
| Structure . Name: |
embryo |
| Notes: |
The Igf2 allele was inherited from the father. |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 9.5 |
| Stage: |
15 |
| Structure . Name: |
embryo |
| Notes: |
The Igf2 allele was inherited from the father. |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 9.5 |
| Stage: |
15 |
| Structure . Name: |
embryo |
| Notes: |
The Igf2 allele was inherited from the father. |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 9.5 |
| Stage: |
15 |
| Structure . Name: |
embryo |
| Notes: |
The Igf2 allele was inherited from the father. |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 9.5 |
| Stage: |
15 |
| Structure . Name: |
embryo |
| Notes: |
The Igf2 allele was inherited from the father. |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 9.5 |
| Stage: |
15 |
| Structure . Name: |
embryo |
| Notes: |
The Igf2 allele was inherited from the father. |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Reed MR |
| Year: |
2001 |
| Journal: |
Genomics |
| Title: |
A complex duplication created by gene targeting at the imprinted H19 locus results in two classes of methylation and correlated Igf2 expression phenotypes. |
| Volume: |
74 |
| Issue: |
2 |
| Pages: |
186-96 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Regué L |
| Year: |
2019 |
| Journal: |
J Biol Chem |
| Title: |
Liver-specific deletion of IGF2 mRNA binding protein-2/IMP2 reduces hepatic fatty acid oxidation and increases hepatic triglyceride accumulation. |
| Volume: |
294 |
| Issue: |
31 |
| Pages: |
11944-11951 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mellott TJ |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
IGF2 ameliorates amyloidosis, increases cholinergic marker expression and raises BMP9 and neurotrophin levels in the hippocampus of the APPswePS1dE9 Alzheimer's disease model mice. |
| Volume: |
9 |
| Issue: |
4 |
| Pages: |
e94287 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kaneda A |
| Year: |
2007 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk. |
| Volume: |
104 |
| Issue: |
52 |
| Pages: |
20926-31 |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
579
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 9.5 |
| Stage: |
15 |
| Structure . Name: |
embryo |
| Notes: |
The Igf2 allele was inherited from the father; he was Igf2+/-;Trp53+/-. |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 9.5 |
| Stage: |
15 |
| Structure . Name: |
embryo |
| Notes: |
The Igf2 allele was inherited from the father; he was Igf2+/-;Trp53+/-. |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 9.5 |
| Stage: |
15 |
| Structure . Name: |
embryo |
| Notes: |
The Igf2 allele was inherited from the father; he was Igf2+/-;Trp53+/-. |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 9.5 |
| Stage: |
15 |
| Structure . Name: |
embryo |
| Notes: |
The Igf2 allele was inherited from the father; like his offspring, he was Igf2+/-;Trp53+/-. |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 9.5 |
| Stage: |
15 |
| Structure . Name: |
embryo |
| Notes: |
The Igf2 allele was inherited from the father; like his offspring, he was Igf2+/-;Trp53+/-. |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 9.5 |
| Stage: |
15 |
| Structure . Name: |
embryo |
| Notes: |
The Igf2 allele was inherited from the father; like his offspring, he was Igf2+/-;Trp53+/-. |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
592
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
530
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Male |
| Age: |
postnatal day 120 |
| Stage: |
28 |
| Structure . Name: |
small intestine crypt of lieberkuhn |
| Notes: |
this animal has not experienced loss of imprinting; it could be carrying a maternal Igf2 allele, which has been silenced |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Male |
| Age: |
postnatal day 120 |
| Stage: |
28 |
| Structure . Name: |
small intestine crypt of lieberkuhn |
| Notes: |
this animal has not experienced loss of imprinting; it could be carrying a maternal Igf2 allele, which has been silenced |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal day 120 |
| Stage: |
28 |
| Structure . Name: |
small intestine crypt of lieberkuhn |
| Notes: |
this animal has not experienced loss of imprinting; it could be carrying a maternal Igf2 allele, which has been silenced |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| Regulatory Region |
| Type: |
silencer |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Allele |
| Name: |
regulatory region 28; targeted mutation 1, Shirley M Tilghman |
| Allele Type: |
Targeted |
| Attribute String: |
Modified regulatory region, Null/knockout |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
577
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE8583 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mori H |
| Year: |
2001 |
| Journal: |
J Neurosci Res |
| Title: |
Expression of mouse igf2 mRNA-binding protein 3 and its implications for the developing central nervous system. |
| Volume: |
64 |
| Issue: |
2 |
| Pages: |
132-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pant V |
| Year: |
2003 |
| Journal: |
Genes Dev |
| Title: |
The nucleotides responsible for the direct physical contact between the chromatin insulator protein CTCF and the H19 imprinting control region manifest parent of origin-specific long-distance insulation and methylation-free domains. |
| Volume: |
17 |
| Issue: |
5 |
| Pages: |
586-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liao J |
| Year: |
2023 |
| Journal: |
Sci Adv |
| Title: |
Establishment of paternal methylation imprint at the H19/Igf2 imprinting control region. |
| Volume: |
9 |
| Issue: |
36 |
| Pages: |
eadi2050 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Park K-S |
| Year: |
2021 |
| Journal: |
bioRxiv |
| Title: |
Cardiac pathologies in mouse loss of imprinting models are due to misexpression of H19 long noncoding RNA. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Park KS |
| Year: |
2021 |
| Journal: |
Elife |
| Title: |
Cardiac pathologies in mouse loss of imprinting models are due to misexpression of H19 long noncoding RNA. |
| Volume: |
10 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Regué L |
| Year: |
2019 |
| Journal: |
Mol Cell Biol |
| Title: |
IMP2 Increases Mouse Skeletal Muscle Mass and Voluntary Activity by Enhancing Autocrine Insulin-Like Growth Factor 2 Production and Optimizing Muscle Metabolism. |
| Volume: |
39 |
| Issue: |
7 |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion Laura, Christopher F Graham |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion Leroy, Christopher F Graham |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion Lesley, Christopher F Graham |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion Lorna, Christopher F Graham |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vernucci M |
| Year: |
2004 |
| Journal: |
Hum Mol Genet |
| Title: |
Developmentally regulated functions of the H19 differentially methylated domain. |
| Volume: |
13 |
| Issue: |
3 |
| Pages: |
353-61 |
|
•
•
•
•
•
|