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Search results 2101 to 2200 out of 6467 for Myc

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Type Details Score
Publication
9797456 | -
First Author: Taira T
Year: 1998
Journal: Genes Cells
Title: AMY-1, a novel C-MYC binding protein that stimulates transcription activity of C-MYC.
Volume: 3
Issue: 8
Pages: 549-65
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Protein Domain
IPR026060 | AMY1
Type: Family
Description: AMY1 (associate of Myc1) family consists of the c-Myc-binding proteins that stimulate c-Myc transcription activity [].
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Protein Domain
IPR003327 | Myc-LZ
Type: Domain
Description: This family consists of the leucine zipper dimerisation domain found in both cellular c-Myc proto-oncogenes and viral v-Myc oncogenes. Dimerisation via the leucine zipper motif with other basic helix-loop-helix-leucinezipper (b/HLH/lz) proteins is required for efficient DNA binding []. The Myc-Maxdimer is a transactivating complex activating expression of growth related genes promoting cell proliferation.The dimerisation is facilitated via interdigitating leucine residues every 7th position of the alpha helix. Likecharge repulsion of adjacent residues in this region preturbs the formation of homodimers with heterodimersbeing promoted by opposing charge attractions. It has been demonstrated that in transgenic mice the balance between oncogene-induced proliferation and apoptosis in a given tissue can be a critical determinant in the initiation and maintenance of the tumor [].
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
29184203 | J:256001
First Author: Jung EM
Year: 2017
Journal: Nat Neurosci
Title: Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior.
Volume: 20
Issue: 12
Pages: 1694-1707
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Publication
8288233 | J:15567
First Author: Warden CH
Year: 1993
Journal: Genomics
Title: Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse.
Volume: 18
Issue: 2
Pages: 295-307
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Publication
24550112 | J:208419
First Author: Basta JM
Year: 2014
Journal: Development
Title: Sall1 balances self-renewal and differentiation of renal progenitor cells.
Volume: 141
Issue: 5
Pages: 1047-58
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Publication
26764350 | J:232444
First Author: Li S
Year: 2016
Journal: Biol Reprod
Title: Ggnbp2 Is Essential for Pregnancy Success via Regulation of Mouse Trophoblast Stem Cell Proliferation and Differentiation.
Volume: 94
Issue: 2
Pages: 41
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Publication
30352686 | J:270543
First Author: Tanahashi H
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Deletion of Lrp4 increases the incidence of microphthalmia.
Volume: 506
Issue: 3
Pages: 478-484
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Publication
19796622 | J:154112
First Author: Nishiyama A
Year: 2009
Journal: Cell Stem Cell
Title: Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors.
Volume: 5
Issue: 4
Pages: 420-33
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
19515997 | J:154534
First Author: Martinez G
Year: 2009
Journal: Invest Ophthalmol Vis Sci
Title: Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.
Volume: 50
Issue: 10
Pages: 4794-806
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Publication
17609113 | J:123923
First Author: Zhou Q
Year: 2007
Journal: Dev Cell
Title: A multipotent progenitor domain guides pancreatic organogenesis.
Volume: 13
Issue: 1
Pages: 103-14
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Publication
24859004 | J:219394
First Author: Boroviak T
Year: 2014
Journal: Nat Cell Biol
Title: The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification.
Volume: 16
Issue: 6
Pages: 516-28
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
22560297 | J:184521
First Author: Koss M
Year: 2012
Journal: Dev Cell
Title: Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
Volume: 22
Issue: 5
Pages: 913-26
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
29031500 | J:257654
First Author: Memic F
Year: 2018
Journal: Gastroenterology
Title: Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.
Volume: 154
Issue: 3
Pages: 624-636
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Publication
22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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Publication
16893186 | J:326274
First Author: Burton RA
Year: 2006
Journal: Biochemistry
Title: B-myc: N-terminal recognition of myc binding proteins.
Volume: 45
Issue: 32
Pages: 9857-65
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
21731673 | J:174767
First Author: Tang F
Year: 2011
Journal: PLoS One
Title: Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
Volume: 6
Issue: 6
Pages: e21208
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Strain
MGI:5905333 | FVB.Cg-Tg(Camk2a-Grik2)28Cmul/Orl
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:5905332 | B6.Cg-Tg(Camk2a-Grik2)28Cmul/Orl
Attribute String: transgenic, mutant strain, congenic
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Publication
12845679 | J:85023
First Author: Drotar ME
Year: 2003
Journal: Int J Cancer
Title: Epstein-Barr virus nuclear antigen-1 and Myc cooperate in lymphomagenesis.
Volume: 106
Issue: 3
Pages: 388-95
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Publication
8414519 | J:88485
First Author: Haupt Y
Year: 1993
Journal: Oncogene
Title: bmi-1 transgene induces lymphomas and collaborates with myc in tumorigenesis.
Volume: 8
Issue: 11
Pages: 3161-4
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Publication
25395170 | J:225145
 
First Author: Chen J
Year: 2014
Journal: Nat Commun
Title: CSN6 drives carcinogenesis by positively regulating Myc stability.
Volume: 5
Pages: 5384
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Publication
26152922 | J:227233
First Author: Castell A
Year: 2015
Journal: Cancer Discov
Title: Targeting MYC Translation in Colorectal Cancer.
Volume: 5
Issue: 7
Pages: 701-3
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Protein
O08539
Organism: Mus musculus/domesticus
Length: 588  
Fragment?: false
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Protein
O08539-2
Organism: Mus musculus/domesticus
Length: 434  
Fragment?: false
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Protein
Q6P1B9
Organism: Mus musculus/domesticus
Length: 477  
Fragment?: false
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Publication
15371245 | -
First Author: Steppan S
Year: 2004
Journal: Syst Biol
Title: Phylogeny and divergence-date estimates of rapid radiations in muroid rodents based on multiple nuclear genes.
Volume: 53
Issue: 4
Pages: 533-53
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Protein
A0A3Q4EBK4
Organism: Mus musculus/domesticus
Length: 410  
Fragment?: false
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Publication
12384613 | -
First Author: Smith S
Year: 2002
Journal: Nucleic Acids Res
Title: The effects of sequence length and oligonucleotide mismatches on 5' exonuclease assay efficiency.
Volume: 30
Issue: 20
Pages: e111
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Protein
A0A3Q4EBR8
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: true
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Publication
32160543 | J:288247
First Author: Rohrberg J
Year: 2020
Journal: Cell Rep
Title: MYC Dysregulates Mitosis, Revealing Cancer Vulnerabilities.
Volume: 30
Issue: 10
Pages: 3368-3382.e7
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HT Experiment
E-GEOD-41219 | Mice Lacking a Myc Enhancer Element that Includes Human SNP rs6983267 Are Resistant to Intestinal Tumors
Series Id: GSE41219
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Interaction Experiment
Raffeiner P (2017)
Description: Calcium-dependent binding of Myc to calmodulin.
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Publication
24951594 | J:220498
First Author: Garcia-Sanz P
Year: 2014
Journal: J Biol Chem
Title: Sin3b interacts with Myc and decreases Myc levels.
Volume: 289
Issue: 32
Pages: 22221-36
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Protein
Q6P8Z1
Organism: Mus musculus/domesticus
Length: 170  
Fragment?: false
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Protein
A0PJL6
Organism: Mus musculus/domesticus
Length: 170  
Fragment?: false
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Publication
2827002 | -
First Author: Kaye F
Year: 1988
Journal: Mol Cell Biol
Title: Structure and expression of the human L-myc gene reveal a complex pattern of alternative mRNA processing.
Volume: 8
Issue: 1
Pages: 186-95
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Publication
3018999 | -
First Author: Stewart MA
Year: 1986
Journal: Virology
Title: Conservation of the c-myc coding sequence in transduced feline v-myc genes.
Volume: 154
Issue: 1
Pages: 121-34
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Publication
15743832 | J:97664
First Author: Cardone M
Year: 2005
Journal: Mol Cell Biol
Title: The novel ETS factor TEL2 cooperates with Myc in B lymphomagenesis.
Volume: 25
Issue: 6
Pages: 2395-405
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Publication
32101699 | J:354586
First Author: Qiu Z
Year: 2020
Journal: Cell Chem Biol
Title: MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome.
Volume: 27
Issue: 5
Pages: 538-550.e7
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HT Experiment
GSE77482 | Pin1 is required for sustained B cell proliferation upon oncogenic activation of Myc
Series Id: E-GEOD-77482
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
36068335 | J:329188
First Author: Winkler R
Year: 2022
Journal: Oncogene
Title: Targeting the MYC interaction network in B-cell lymphoma via histone deacetylase 6 inhibition.
Volume: 41
Issue: 40
Pages: 4560-4572
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Publication
2828024 | J:9008
First Author: Legouy E
Year: 1987
Journal: EMBO J
Title: Structure and expression of the murine L-myc gene.
Volume: 6
Issue: 11
Pages: 3359-66
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Publication
1409609 | J:2643
First Author: Beier DR
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Mapping genes in the mouse using single-strand conformation polymorphism analysis of recombinant inbred strains and interspecific crosses.
Volume: 89
Issue: 19
Pages: 9102-6
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Gene
362131 | Max-ps1
Type: gene
Organism: rat
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Gene
418808 | MYCBP2
Type: gene
Organism: chicken
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Gene
30686 | myca
Type: gene
Organism: zebrafish
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Gene
393141 | mycb
Type: gene
Organism: zebrafish
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Gene
100379925 | mycbp2
Type: gene
Organism: frog, western clawed
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Gene
120093177 | Max-ps2
Type: gene
Organism: rat
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Gene
108703931 | maz.L
Type: gene
Organism: frog, African clawed
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Gene
373652 | max.S
Type: gene
Organism: frog, African clawed
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Gene
379052 | myc.S
Type: gene
Organism: frog, African clawed
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Gene
398491 | maz.S
Type: gene
Organism: frog, African clawed
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Gene
399315 | myc.L
Type: gene
Organism: frog, African clawed
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Gene
504192 | max.L
Type: gene
Organism: frog, African clawed
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Publication
16140930 | J:102146
First Author: Park SS
Year: 2005
Journal: Cancer Res
Title: Insertion of Myc into Igh accelerates peritoneal plasmacytomas in mice.
Volume: 65
Issue: 17
Pages: 7644-52
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GXD Expression
GXD Expression
 
Probe: MGI:7853888
Assay Type: RNA in situ
Annotation Date: 2025-01-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7852795
Age: embryonic day 14.5
Note: Exocrine cell marker. Expression overlaps completely with Myc staining.
Specimen Label: 2A
Detected: true
Specimen Num: 1
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Publication
23665224 | J:198686
First Author: Babetto E
Year: 2013
Journal: Cell Rep
Title: The Phr1 ubiquitin ligase promotes injury-induced axon self-destruction.
Volume: 3
Issue: 5
Pages: 1422-9
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Allele
Mycbp<+> | MGI:2439548
   
Name: MYC binding protein; wild type
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Allele
Myct1<+> | MGI:3049052
   
Name: myc target 1; wild type
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Publication
2654812 | J:9772
First Author: Campbell GR
Year: 1989
Journal: Oncogene Res
Title: Chromosomal location of N-myc and L-myc genes in the mouse.
Volume: 4
Issue: 1
Pages: 47-54
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Allele
Myc<tm1.1Itl> | MGI:5444112
 
Name: myelocytomatosis oncogene; targeted mutation 1.1, inGenious Targeting Laboratory
Allele Type: Targeted
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Publication
25311243 | J:220198
First Author: Ortega M
Year: 2015
Journal: Leukemia
Title: A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B- and T-cell malignancies.
Volume: 29
Issue: 4
Pages: 968-76
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Publication
9824157 | J:153799
First Author: Soucek L
Year: 1998
Journal: Oncogene
Title: Design and properties of a Myc derivative that efficiently homodimerizes.
Volume: 17
Issue: 19
Pages: 2463-72
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Publication
15753301 | J:97189
First Author: Refaeli Y
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: The protooncogene MYC can break B cell tolerance.
Volume: 102
Issue: 11
Pages: 4097-102
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Publication
8425218 | J:19396
First Author: Ayer DE
Year: 1993
Journal: Cell
Title: Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity.
Volume: 72
Issue: 2
Pages: 211-22
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Publication
2419762 | J:8211
First Author: Zimmerman KA
Year: 1986
Journal: Nature
Title: Differential expression of myc family genes during murine development.
Volume: 319
Issue: 6056
Pages: 780-3
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HT Experiment
E-GEOD-55272 | Reduced Expression of the Proto-oncogene Myc Increases Mouse Longevity and Enhances Healthspan
Series Id: GSE55272
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
16815105 | J:112204
First Author: Janz S
Year: 2006
Journal: DNA Repair (Amst)
Title: Myc translocations in B cell and plasma cell neoplasms.
Volume: 5
Issue: 9-10
Pages: 1213-24
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Publication
20519624 | J:164528
First Author: den Hollander J
Year: 2010
Journal: Blood
Title: Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state.
Volume: 116
Issue: 9
Pages: 1498-505
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Publication
17464290 | J:121564
First Author: Keller UB
Year: 2007
Journal: EMBO J
Title: Myc targets Cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis.
Volume: 26
Issue: 10
Pages: 2562-74
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Publication
16537801 | J:110242
First Author: Smith DP
Year: 2006
Journal: Blood
Title: MYC levels govern hematopoietic tumor type and latency in transgenic mice.
Volume: 108
Issue: 2
Pages: 653-61
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Publication
31395740 | J:284176
First Author: Mathsyaraja H
Year: 2019
Journal: Genes Dev
Title: Max deletion destabilizes MYC protein and abrogates Eµ-Myc lymphomagenesis.
Volume: 33
Issue: 17-18
Pages: 1252-1264
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Publication
26387865 | J:235841
First Author: Altman BJ
Year: 2015
Journal: Cell Metab
Title: MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells.
Volume: 22
Issue: 6
Pages: 1009-19
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Publication
28410006 | J:309805
First Author: Gomes LR
Year: 2017
Journal: Autophagy
Title: Chaperone-mediated autophagy prevents cellular transformation by regulating MYC proteasomal degradation.
Volume: 13
Issue: 5
Pages: 928-940
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Publication
1986238 | J:93929
First Author: Ma A
Year: 1991
Journal: Mol Cell Biol
Title: Mechanism of endogenous myc gene down-regulation in E mu-N-myc tumors.
Volume: 11
Issue: 1
Pages: 440-4
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Publication
16935001 | J:114892
First Author: Arvanitis C
Year: 2006
Journal: Semin Cancer Biol
Title: Conditional transgenic models define how MYC initiates and maintains tumorigenesis.
Volume: 16
Issue: 4
Pages: 313-7
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Publication
35203395 | J:321511
 
First Author: Prochownik EV
Year: 2022
Journal: Cells
Title: Normal and Neoplastic Growth Suppression by the Extended Myc Network.
Volume: 11
Issue: 4
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Publication
33658356 | J:303692
 
First Author: Kabir AU
Year: 2021
Journal: Sci Transl Med
Title: Dual role of endothelial Myct1 in tumor angiogenesis and tumor immunity.
Volume: 13
Issue: 583
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Publication
28368423 | J:248153
First Author: Moyo TK
Year: 2017
Journal: Oncogene
Title: Myc enhances B-cell receptor signaling in precancerous B cells and confers resistance to Btk inhibition.
Volume: 36
Issue: 32
Pages: 4653-4661
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Publication
2250704 | J:69571
First Author: Strasser A
Year: 1990
Journal: Nature
Title: Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.
Volume: 348
Issue: 6299
Pages: 331-3
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Publication
37621775 | J:339288
 
First Author: Prochownik EV
Year: 2023
Journal: Front Cell Dev Biol
Title: Lessons in aging from Myc knockout mouse models.
Volume: 11
Pages: 1244321
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Publication
32188705 | J:288814
First Author: Liu Z
Year: 2020
Journal: Cancer Discov
Title: Mutations in the RNA Splicing Factor SF3B1 Promote Tumorigenesis through MYC Stabilization.
Volume: 10
Issue: 6
Pages: 806-821
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Publication
25322691 | J:217888
First Author: Priolo C
Year: 2014
Journal: Cancer Res
Title: AKT1 and MYC induce distinctive metabolic fingerprints in human prostate cancer.
Volume: 74
Issue: 24
Pages: 7198-204
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Interaction Experiment
Sansom OJ (2007)
Description: Myc deletion rescues Apc deficiency in the small intestine.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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