|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 2201 to 2300 out of 2498 for Arpp21

<< First    < Previous  |  Next >    Last >>
0.052s

Categories

Hits by Category

Hits by Strain

Type Details Score
Publication
30742116 | J:277505
First Author: Cruz Hern?ndez JC
Year: 2019
Journal: Nat Neurosci
Title: Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer's disease mouse models.
Volume: 22
Issue: 3
Pages: 413-420
•
•
•
•
•
Publication
30383537 | J:368398
First Author: Lu CD
Year: 2018
Journal: Aging (Albany NY)
Title: Transferrin is responsible for mediating the effects of iron ions on the regulation of anterior pharynx-defective-1?/? and Presenilin 1 expression via PGE(2) and PGD(2) at the early stage of Alzheimer's Disease.
Volume: 10
Issue: 11
Pages: 3117-3135
•
•
•
•
•
Publication
31392591 | J:368408
First Author: Guan PP
Year: 2019
Journal: Neurotherapeutics
Title: Cyclooxygenase-2 Induced the ?-Amyloid Protein Deposition and Neuronal Apoptosis Via Upregulating the Synthesis of Prostaglandin E(2) and 15-Deoxy-?(12,14)-prostaglandin J(2).
Volume: 16
Issue: 4
Pages: 1255-1268
•
•
•
•
•
Publication
30899091 | J:368405
First Author: Sharoar MG
Year: 2019
Journal: Mol Psychiatry
Title: Sequential formation of different layers of dystrophic neurites in Alzheimer's brains.
Volume: 24
Issue: 9
Pages: 1369-1382
•
•
•
•
•
Publication
26779813 | J:233342
First Author: Baruch K
Year: 2016
Journal: Nat Med
Title: PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease.
Volume: 22
Issue: 2
Pages: 135-7
•
•
•
•
•
Publication
42097136 | J:386135
     
First Author: Tang JY
Year: 2026
Journal: Neuron
Title: Hepatic expression of APOE3 Christchurch mitigates APOE4-related Alzheimer's disease pathologies in mice.
•
•
•
•
•
Publication
37304021 | J:346937
 
First Author: Na D
Year: 2023
Journal: Front Neurosci
Title: Increased central auditory gain in 5xFAD Alzheimer's disease mice as an early biomarker candidate for Alzheimer's disease diagnosis.
Volume: 17
Pages: 1106570
•
•
•
•
•
Publication
34312508 | J:368338
First Author: Duan Y
Year: 2022
Journal: Nat Biomed Eng
Title: Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer's disease alleviates amyloid-related pathologies in mice.
Volume: 6
Issue: 2
Pages: 168-180
•
•
•
•
•
Publication
34702328 | J:316743
First Author: Li X
Year: 2021
Journal: Mol Neurodegener
Title: Synaptic dysfunction of Aldh1a1 neurons in the ventral tegmental area causes impulsive behaviors.
Volume: 16
Issue: 1
Pages: 73
•
•
•
•
•
Publication
25837283 | J:368377
First Author: Rumbaugh G
Year: 2015
Journal: Neuropsychopharmacology
Title: Pharmacological Selectivity Within Class I Histone Deacetylases Predicts Effects on Synaptic Function and Memory Rescue.
Volume: 40
Issue: 10
Pages: 2307-16
•
•
•
•
•
Publication
29262525 | J:368393
First Author: Zheng SQ
Year: 2017
Journal: Oncotarget
Title: Prostaglandin I(2) is responsible for ameliorating prostaglandin E(2) stress in stimulating the expression of tumor necrosis factor ? in a ?-amyloid protein -dependent mechanism.
Volume: 8
Issue: 61
Pages: 102801-102819
•
•
•
•
•
Publication
40790270 | J:386172
First Author: Pagano Zottola AC
Year: 2025
Journal: Nat Neurosci
Title: Potentiation of mitochondrial function by mitoDREADD-G(s) reverses pharmacological and neurodegenerative cognitive impairment in mice.
Volume: 28
Issue: 9
Pages: 1844-1857
•
•
•
•
•
Publication
33667711 | J:305937
 
First Author: Mitsubori M
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Identification of highest neurotoxic amyloid-? plaque type showing reduced contact with astrocytes.
Volume: 549
Pages: 67-74
•
•
•
•
•
Publication
40438149 | J:367830
First Author: Fulopova B
Year: 2025
Journal: Neurophotonics
Title: Repetitive transcranial magnetic stimulation increases synaptic plasticity of cortical axons in the APP/PS1 amyloidosis mouse model.
Volume: 12
Issue: Suppl 1
Pages: S14613
•
•
•
•
•
Publication
40499846 | J:369189
 
First Author: Sola-Sevilla N
Year: 2025
Journal: Brain Behav Immun
Title: Microglial SIRT2 deficiency aggravates cognitive decline and amyloid pathology in Alzheimer's disease.
Volume: 129
Pages: 223-243
•
•
•
•
•
Publication
37433006 | J:362060
First Author: Zhang S
Year: 2023
Journal: Sci Signal
Title: TRPM7 kinase activity induces amyloid-? degradation to reverse synaptic and cognitive deficits in mouse models of Alzheimer's disease.
Volume: 16
Issue: 793
Pages: eade6325
•
•
•
•
•
Publication
20231476 | J:158919
First Author: Heneka MT
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine.
Volume: 107
Issue: 13
Pages: 6058-63
•
•
•
•
•
Publication
35217767 | J:321961
First Author: Murie M
Year: 2022
Journal: Commun Biol
Title: ATase inhibition rescues age-associated proteotoxicity of the secretory pathway.
Volume: 5
Issue: 1
Pages: 173
•
•
•
•
•
Publication
35927581 | J:351737
First Author: Jung H
Year: 2022
Journal: Nat Med
Title: Anti-inflammatory clearance of amyloid-? by a chimeric Gas6 fusion protein.
Volume: 28
Issue: 9
Pages: 1802-1812
•
•
•
•
•
Publication
39334471 | J:355025
First Author: Robertson KV
Year: 2024
Journal: J Neuroinflammation
Title: Knockdown of microglial iron import gene, Slc11a2, worsens cognitive function and alters microglial transcriptional landscape in a sex-specific manner in the APP/PS1 model of Alzheimer's disease.
Volume: 21
Issue: 1
Pages: 238
•
•
•
•
•
Publication
25940071 | J:222768
First Author: Baruch K
Year: 2015
Journal: EMBO J
Title: Cerebral nitric oxide represses choroid plexus NF?B-dependent gateway activity for leukocyte trafficking.
Volume: 34
Issue: 13
Pages: 1816-28
•
•
•
•
•
Publication
34080759 | J:311271
First Author: Zhang J
Year: 2021
Journal: Aging Cell
Title: Neuronal loss and microgliosis are restricted to the core of A? deposits in mouse models of Alzheimer's disease.
Volume: 20
Issue: 6
Pages: e13380
•
•
•
•
•
Publication
34107254 | J:311267
First Author: Hu Y
Year: 2021
Journal: Cell Rep
Title: Replicative senescence dictates the emergence of disease-associated microglia and contributes to A? pathology.
Volume: 35
Issue: 10
Pages: 109228
•
•
•
•
•
Publication
33069740 | J:311260
 
First Author: Tan X
Year: 2021
Journal: Behav Brain Res
Title: Isoorientin, a GSK-3? inhibitor, rescues synaptic dysfunction, spatial memory deficits and attenuates pathological progression in APP/PS1 model mice.
Volume: 398
Pages: 112968
•
•
•
•
•
Publication
17476306 | J:122560
First Author: Hu X
Year: 2007
Journal: EMBO J
Title: Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities.
Volume: 26
Issue: 11
Pages: 2755-67
•
•
•
•
•
Publication
36443837 | J:351743
First Author: Lee HY
Year: 2022
Journal: Alzheimers Res Ther
Title: Aryloxypropanolamine targets amyloid aggregates and reverses Alzheimer-like phenotypes in Alzheimer mouse models.
Volume: 14
Issue: 1
Pages: 177
•
•
•
•
•
Publication
42218995 | J:386970
 
First Author: Li H
Year: 2026
Journal: Neuropharmacology
Title: GPR139-mediated cholinergic circuit from the medial septum to the ventral hippocampal CA3 modulates cognitive impairment in Alzheimer's disease.
Volume: 298
Pages: 111043
•
•
•
•
•
Publication
25650666 | J:238174
First Author: Chang JY
Year: 2015
Journal: Oncotarget
Title: Trafficking protein particle complex 6A delta (TRAPPC6A?) is an extracellular plaque-forming protein in the brain.
Volume: 6
Issue: 6
Pages: 3578-89
•
•
•
•
•
Publication
32666270 | J:311366
First Author: Readhead B
Year: 2020
Journal: Acta Neuropathol
Title: miR155 regulation of behavior, neuropathology, and cortical transcriptomics in Alzheimer's disease.
Volume: 140
Issue: 3
Pages: 295-315
•
•
•
•
•
Publication
36721026 | J:351747
First Author: Matsuzaki M
Year: 2023
Journal: Mol Psychiatry
Title: ADAMTS4 is involved in the production of the Alzheimer disease amyloid biomarker APP669-711.
Volume: 28
Issue: 4
Pages: 1802-1812
•
•
•
•
•
Publication
24136196 | J:207213
First Author: Cheng S
Year: 2013
Journal: J Biol Chem
Title: Farnesyltransferase haplodeficiency reduces neuropathology and rescues cognitive function in a mouse model of Alzheimer disease.
Volume: 288
Issue: 50
Pages: 35952-60
•
•
•
•
•
Publication
25904803 | J:352207
First Author: Savage JC
Year: 2015
Journal: J Neurosci
Title: Nuclear receptors license phagocytosis by trem2+ myeloid cells in mouse models of Alzheimer's disease.
Volume: 35
Issue: 16
Pages: 6532-43
•
•
•
•
•
Publication
39044253 | J:358513
First Author: Kim S
Year: 2024
Journal: Mol Neurodegener
Title: Astrocytic autophagy plasticity modulates A? clearance and cognitive function in Alzheimer's disease.
Volume: 19
Issue: 1
Pages: 55
•
•
•
•
•
Publication
41313780 | J:387038
First Author: Li L
Year: 2025
Journal: Sci Adv
Title: Gut microbial-derived indole-3-propionate improves cognitive function in Alzheimer's disease.
Volume: 11
Issue: 48
Pages: eadw8410
•
•
•
•
•
Publication
41650876 | J:383176
 
First Author: Charlton PE
Year: 2026
Journal: Hear Res
Title: Differences in hearing across the lifespan in two strains of Alzheimer's mouse models as measured using behavioral and physiological techniques.
Volume: 472
Pages: 109550
•
•
•
•
•
Publication
41785850 | J:387010
First Author: Teng F
Year: 2026
Journal: Cell
Title: Efficient amyloid-?? degradation in Alzheimer's disease using SPYTACs.
Volume: 189
Issue: 7
Pages: 1923-1941.e26
•
•
•
•
•
Publication
31277944 | J:291220
First Author: Feng D
Year: 2019
Journal: Biochem Biophys Res Commun
Title: CD200 dysfunction in neuron contributes to synaptic deficits and cognitive impairment.
Volume: 516
Issue: 4
Pages: 1053-1059
•
•
•
•
•
Publication
39504519 | J:359514
First Author: Welikovitch LA
Year: 2025
Journal: Brain
Title: Tau, synapse loss and gliosis progress in an Alzheimer's mouse model after amyloid-? immunotherapy.
Volume: 148
Issue: 4
Pages: 1316-1328
•
•
•
•
•
Publication
37193353 | J:352427
First Author: Li L
Year: 2022
Journal: Cell Insight
Title: A selective degeneration of cholinergic neurons mediated by NRADD in an Alzheimer's disease mouse model.
Volume: 1
Issue: 6
Pages: 100060
•
•
•
•
•
Publication
34209113 | J:322203
 
First Author: Camargo LC
Year: 2021
Journal: Int J Mol Sci
Title: PEA? Triggers Cognitive Decline and Amyloid Burden in a Novel Mouse Model of Alzheimer's Disease.
Volume: 22
Issue: 13
•
•
•
•
•
Publication
40506544 | J:369764
First Author: da Rocha JF
Year: 2025
Journal: Nat Neurosci
Title: Protective exercise responses in the dentate gyrus of Alzheimer's disease mouse model revealed with single-nucleus RNA-sequencing.
Volume: 28
Issue: 7
Pages: 1546-1561
•
•
•
•
•
Publication
27516385 | J:238562
First Author: Kajiwara Y
Year: 2016
Journal: Hum Mol Genet
Title: The human-specific CASP4 gene product contributes to Alzheimer-related synaptic and behavioural deficits.
Volume: 25
Issue: 19
Pages: 4315-4327
•
•
•
•
•
Publication
30040874 | J:272683
First Author: Granger MW
Year: 2019
Journal: J Neurochem
Title: Distinct disruptions in Land's cycle remodeling of glycerophosphocholines in murine cortex mark symptomatic onset and progression in two Alzheimer's disease mouse models.
Volume: 149
Issue: 4
Pages: 499-517
•
•
•
•
•
Publication
28886753 | J:361143
First Author: Hollands C
Year: 2017
Journal: Mol Neurodegener
Title: Depletion of adult neurogenesis exacerbates cognitive deficits in Alzheimer's disease by compromising hippocampal inhibition.
Volume: 12
Issue: 1
Pages: 64
•
•
•
•
•
Publication
31034995 | J:352650
 
First Author: Liang F
Year: 2019
Journal: Behav Brain Res
Title: Social housing promotes cognitive function through enhancing synaptic plasticity in APP/PS1 mice.
Volume: 368
Pages: 111910
•
•
•
•
•
Publication
27723233 | J:238754
First Author: Martin E
Year: 2017
Journal: Aging Cell
Title: Distinct inflammatory phenotypes of microglia and monocyte-derived macrophages in Alzheimer's disease models: effects of aging and amyloid pathology.
Volume: 16
Issue: 1
Pages: 27-38
•
•
•
•
•
Publication
28758999 | J:258017
First Author: Caccamo A
Year: 2017
Journal: Nat Neurosci
Title: Necroptosis activation in Alzheimer's disease.
Volume: 20
Issue: 9
Pages: 1236-1246
•
•
•
•
•
Publication
32514139 | J:298290
First Author: Poll S
Year: 2020
Journal: Nat Neurosci
Title: Memory trace interference impairs recall in a mouse model of Alzheimer's disease.
Volume: 23
Issue: 8
Pages: 952-958
•
•
•
•
•
Publication
19625507 | J:151798
First Author: Shi Q
Year: 2009
Journal: J Neurosci
Title: Reduced amyloid deposition in mice overexpressing RTN3 is adversely affected by preformed dystrophic neurites.
Volume: 29
Issue: 29
Pages: 9163-73
•
•
•
•
•
Publication
38041158 | J:355289
First Author: Zhao Q
Year: 2023
Journal: Mol Neurodegener
Title: Sleep restoration by optogenetic targeting of GABAergic neurons reprograms microglia and ameliorates pathological phenotypes in an Alzheimer's disease model.
Volume: 18
Issue: 1
Pages: 93
•
•
•
•
•
Publication
23933749 | J:203865
First Author: Ma T
Year: 2013
Journal: Nat Neurosci
Title: Suppression of eIF2? kinases alleviates Alzheimer's disease-related plasticity and memory deficits.
Volume: 16
Issue: 9
Pages: 1299-305
•
•
•
•
•
Publication
30216939 | J:271510
 
First Author: Verheijen BM
Year: 2018
Journal: Neurobiol Aging
Title: Paradoxical effects of mutant ubiquitin on A? plaque formation in an Alzheimer mouse model.
Volume: 72
Pages: 62-71
•
•
•
•
•
Publication
40730660 | J:379622
First Author: Kumar S
Year: 2025
Journal: Nat Aging
Title: Serum amyloid P secreted by bone marrow adipocytes drives skeletal amyloidosis.
Volume: 5
Issue: 9
Pages: 1771-1789
•
•
•
•
•
Genotype
Genotype
Symbol: Prnp/Prnp Tg(APPswe,PSEN1dE9)85Dbo/?
Background: B6.Cg-Prnp Tg(APPswe,PSEN1dE9)85Dbo
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Map2k4/Map2k4 Map2k7/Map2k7 Tg(APPswe,PSEN1dE9)85Dbo/? Tg(Camk2a-cre/ERT2)2Gsc/?
Background: involves: C3H * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Agrn/Agrn Tg(APPswe,PSEN1dE9)85Dbo/? Tg(Tek-cre)1Ywa/?
Background: involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Publication
28372324 | J:378941
First Author: Dorey E
Year: 2017
Journal: J Alzheimers Dis
Title: Apolipoprotein E Isoforms Differentially Regulate Alzheimer's Disease and Amyloid-?-Induced Inflammatory Response in vivo and in vitro.
Volume: 57
Issue: 4
Pages: 1265-1279
•
•
•
•
•
Publication
23499462 | J:195341
First Author: Kuszczyk MA
Year: 2013
Journal: Am J Pathol
Title: Blocking the interaction between apolipoprotein E and A? reduces intraneuronal accumulation of A? and inhibits synaptic degeneration.
Volume: 182
Issue: 5
Pages: 1750-68
•
•
•
•
•
Publication
25452762 | J:323481
 
First Author: Renoux AJ
Year: 2014
Journal: Front Genet
Title: Fragile X mental retardation protein expression in Alzheimer's disease.
Volume: 5
Pages: 360
•
•
•
•
•
Publication
40962797 | J:389471
First Author: Zhang J
Year: 2025
Journal: Signal Transduct Target Ther
Title: Bone marrow B lymphopoiesis accelerates early cerebral amyloid pathology.
Volume: 10
Issue: 1
Pages: 312
•
•
•
•
•
Publication
24315369 | J:206139
First Author: Lourenco MV
Year: 2013
Journal: Cell Metab
Title: TNF-? mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's ?-amyloid oligomers in mice and monkeys.
Volume: 18
Issue: 6
Pages: 831-43
•
•
•
•
•
Publication
24307730 | J:207169
First Author: Fisher Y
Year: 2014
Journal: J Immunol
Title: Th1 polarization of T cells injected into the cerebrospinal fluid induces brain immunosurveillance.
Volume: 192
Issue: 1
Pages: 92-102
•
•
•
•
•
Publication
35024626 | J:353179
First Author: Goicoechea L
Year: 2022
Journal: STAR Protoc
Title: GST-Perfringolysin O production for the localization and?quantification of membrane cholesterol in human and mouse brain and liver.
Volume: 3
Issue: 1
Pages: 101068
•
•
•
•
•
Publication
24012003 | J:201741
First Author: Um JW
Year: 2013
Journal: Neuron
Title: Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer a? oligomer bound to cellular prion protein.
Volume: 79
Issue: 5
Pages: 887-902
•
•
•
•
•
Publication
37976283 | J:346798
First Author: Purro SA
Year: 2023
Journal: PLoS One
Title: Two mouse models of Alzheimer's disease accumulate amyloid at different rates and have distinct A? oligomer profiles unaltered by ablation of cellular prion protein.
Volume: 18
Issue: 11
Pages: e0294465
•
•
•
•
•
Publication
24965601 | J:339740
First Author: Vergara C
Year: 2015
Journal: Mol Neurobiol
Title: Role of PrP(C) Expression in Tau Protein Levels and Phosphorylation in Alzheimer's Disease Evolution.
Volume: 51
Issue: 3
Pages: 1206-20
•
•
•
•
•
Publication
27033548 | J:269645
First Author: Hong S
Year: 2016
Journal: Science
Title: Complement and microglia mediate early synapse loss in Alzheimer mouse models.
Volume: 352
Issue: 6286
Pages: 712-716
•
•
•
•
•
Publication
26872418 | J:281483
 
First Author: Ferretti MT
Year: 2016
Journal: Brain Behav Immun
Title: T-cell brain infiltration and immature antigen-presenting cells in transgenic models of Alzheimer's disease-like cerebral amyloidosis.
Volume: 54
Pages: 211-225
•
•
•
•
•
Publication
27196744 | J:234011
   
First Author: Deyts C
Year: 2016
Journal: Elife
Title: Loss of presenilin function is associated with a selective gain of APP function.
Volume: 5
•
•
•
•
•
Publication
24698269 | J:213159
First Author: Sun S
Year: 2014
Journal: Neuron
Title: Reduced synaptic STIM2 expression and impaired store-operated calcium entry cause destabilization of mature spines in mutant presenilin mice.
Volume: 82
Issue: 1
Pages: 79-93
•
•
•
•
•
Publication
27133169 | J:316047
First Author: Jais A
Year: 2016
Journal: Cell
Title: Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity.
Volume: 165
Issue: 4
Pages: 882-95
•
•
•
•
•
Publication
22993429 | J:188282
First Author: Fitz NF
Year: 2012
Journal: J Neurosci
Title: Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice.
Volume: 32
Issue: 38
Pages: 13125-36
•
•
•
•
•
Publication
16207707 | J:105900
First Author: Hirsch-Reinshagen V
Year: 2005
Journal: J Biol Chem
Title: The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease.
Volume: 280
Issue: 52
Pages: 43243-56
•
•
•
•
•
Publication
28241068 | J:246977
First Author: Carter AY
Year: 2017
Journal: PLoS One
Title: Liver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient mice.
Volume: 12
Issue: 2
Pages: e0172161
•
•
•
•
•
Publication
37117599 | J:339502
First Author: March-Diaz R
Year: 2021
Journal: Nat Aging
Title: Hypoxia compromises the mitochondrial metabolism of Alzheimer's disease microglia via HIF1.
Volume: 1
Issue: 4
Pages: 385-399
•
•
•
•
•
Publication
27190010 | J:247501
First Author: Woodling NS
Year: 2016
Journal: Brain
Title: Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer's disease model mice.
Volume: 139
Issue: Pt 7
Pages: 2063-81
•
•
•
•
•
Publication
34272583 | J:350898
First Author: Roos TT
Year: 2021
Journal: Acta Neuropathol
Title: Neuronal spreading and plaque induction of intracellular A? and its disruption of A? homeostasis.
Volume: 142
Issue: 4
Pages: 669-687
•
•
•
•
•
Publication
34417591 | J:335307
First Author: Islam MR
Year: 2021
Journal: Nat Metab
Title: Exercise hormone irisin is a critical regulator of cognitive function.
Volume: 3
Issue: 8
Pages: 1058-1070
•
•
•
•
•
Publication
18256671 | J:132628
First Author: Meyer-Luehmann M
Year: 2008
Journal: Nature
Title: Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease.
Volume: 451
Issue: 7179
Pages: 720-4
•
•
•
•
•
Publication
22082664 | J:220073
First Author: Rauch SM
Year: 2011
Journal: J Neuropathol Exp Neurol
Title: Changes in brain ?-amyloid deposition and aquaporin 4 levels in response to altered agrin expression in mice.
Volume: 70
Issue: 12
Pages: 1124-37
•
•
•
•
•
Publication
38051904 | J:357482
First Author: Li B
Year: 2024
Journal: Neural Regen Res
Title: Neural stem cell-derived exosomes promote mitochondrial biogenesis and restore abnormal protein distribution in a mouse model of Alzheimer's disease.
Volume: 19
Issue: 7
Pages: 1593-1601
•
•
•
•
•
Publication
31219699 | J:284725
First Author: Sheng L
Year: 2019
Journal: FASEB J
Title: Microglial Trem2 induces synaptic impairment at early stage and prevents amyloidosis at late stage in APP/PS1 mice.
Volume: 33
Issue: 9
Pages: 10425-10442
•
•
•
•
•
Publication
28366226 | J:244289
 
First Author: Zheng JY
Year: 2017
Journal: Neurobiol Aging
Title: Selective deletion of apolipoprotein E in astrocytes ameliorates the spatial learning and memory deficits in Alzheimer's disease (APP/PS1) mice by inhibiting TGF-?/Smad2/STAT3 signaling.
Volume: 54
Pages: 112-132
•
•
•
•
•
Publication
26538310 | J:368236
 
First Author: Cherry JD
Year: 2015
Journal: J Neuroinflammation
Title: Arginase 1+ microglia reduce A? plaque deposition during IL-1?-dependent neuroinflammation.
Volume: 12
Pages: 203
•
•
•
•
•
Publication
22114267 | J:178060
First Author: Mazzitelli S
Year: 2011
Journal: J Neurosci
Title: The loss of c-Jun N-terminal protein kinase activity prevents the amyloidogenic cleavage of amyloid precursor protein and the formation of amyloid plaques in vivo.
Volume: 31
Issue: 47
Pages: 16969-76
•
•
•
•
•
Publication
40492499 | J:369897
   
First Author: Yu Z
Year: 2025
Journal: Elife
Title: Activity-dependent synapse elimination requires caspase-3 activation.
Volume: 13
•
•
•
•
•
Publication
30031059 | J:352676
 
First Author: Ren R
Year: 2018
Journal: Life Sci
Title: Specific deletion connexin43 in astrocyte ameliorates cognitive dysfunction in APP/PS1 mice.
Volume: 208
Pages: 175-191
•
•
•
•
•
Publication
40595567 | J:369106
First Author: Su Y
Year: 2025
Journal: Nat Commun
Title: Connexin43 hemichannel blockade turns microglia neuroprotective and mitigates cognitive deficits in a mouse model of amyloidosis.
Volume: 16
Issue: 1
Pages: 5621
•
•
•
•
•
Publication
42319929 | J:388020
First Author: Pan W
Year: 2026
Journal: Sci Adv
Title: Neuronal YTHDF2 suppresses innate immune activation in A?? pathology by promoting m(6)A-dependent decay of cytosolic mitochondrial mRNAs.
Volume: 12
Issue: 25
Pages: eadz0887
•
•
•
•
•
Publication
27103515 | J:235030
 
First Author: Yang W
Year: 2016
Journal: Neurobiol Aging
Title: Repression of the eIF2? kinase PERK alleviates mGluR-LTD impairments in a mouse model of Alzheimer's disease.
Volume: 41
Pages: 19-24
•
•
•
•
•
Publication
38462589 | J:368433
First Author: Ding F
Year: 2024
Journal: Brain
Title: Dysregulation of extracellular potassium distinguishes healthy ageing from neurodegeneration.
Volume: 147
Issue: 5
Pages: 1726-1739
•
•
•
•
•
Publication
32628780 | J:347684
First Author: Kumar V
Year: 2021
Journal: J Neurochem
Title: A validated quantitative method for the assessment of neuroprotective barrier impairment in neurodegenerative disease models.
Volume: 158
Issue: 3
Pages: 807-817
•
•
•
•
•
Publication
36599670 | J:337512
 
First Author: Aghaizu ND
Year: 2023
Journal: eNeuro
Title: Microglial Expression of the Wnt Signaling Modulator DKK2 Differs between Human Alzheimer's Disease Brains and Mouse Neurodegeneration Models.
Volume: 10
Issue: 1
•
•
•
•
•
Publication
38920631 | J:360321
 
First Author: Rombaut B
Year: 2024
Journal: Cells
Title: Early Inhibition of Phosphodiesterase 4B (PDE4B) Instills Cognitive Resilience in APPswe/PS1dE9 Mice.
Volume: 13
Issue: 12
•
•
•
•
•
Publication
22198949 | J:180762
First Author: Liu S
Year: 2012
Journal: J Immunol
Title: TLR2 is a primary receptor for Alzheimer's amyloid ? peptide to trigger neuroinflammatory activation.
Volume: 188
Issue: 3
Pages: 1098-107
•
•
•
•
•
Publication
40300603 | J:369831
First Author: Harris SS
Year: 2025
Journal: Cell
Title: Alzheimer's disease patient-derived high-molecular-weight tau impairs bursting in hippocampal neurons.
Volume: 188
Issue: 14
Pages: 3775-3788.e21
•
•
•
•
•
Publication
27373369 | J:240784
 
First Author: Li T
Year: 2016
Journal: Nat Commun
Title: The neuritic plaque facilitates pathological conversion of tau in an Alzheimer's disease mouse model.
Volume: 7
Pages: 12082
•
•
•
•
•
Publication
31825838 | J:300535
First Author: Pickett EK
Year: 2019
Journal: Cell Rep
Title: Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease.
Volume: 29
Issue: 11
Pages: 3592-3604.e5
•
•
•
•
•
Publication
28500862 | J:243583
First Author: Bennett RE
Year: 2017
Journal: Am J Pathol
Title: Enhanced Tau Aggregation in the Presence of Amyloid ?.
Volume: 187
Issue: 7
Pages: 1601-1612
•
•
•
•
•
Publication
40145102 | J:387611
First Author: Hou SS
Year: 2025
Journal: Neurophotonics
Title: Shallow-angle intracranial cannula for repeated infusion and in vivo imaging with multiphoton microscopy.
Volume: 12
Issue: 2
Pages: 025001
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom