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Search results 2201 to 2300 out of 2795 for Egfr

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Hits by Pathway

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Hits by Strain

Type Details Score
Protein Coding Gene
MGI:97583 | Pik3r1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1206581 | Pik3ca
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P26450
Organism: Mus musculus/domesticus
Length: 724  
Fragment?: false
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Protein
P05480
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: false
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Protein
Q62245
Organism: Mus musculus/domesticus
Length: 1319  
Fragment?: false
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Protein
P42337
Organism: Mus musculus/domesticus
Length: 1068  
Fragment?: false
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Protein Coding Gene
MGI:98296 | Shc1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
35624211 | J:330339
First Author: Yeo AT
Year: 2022
Journal: Nat Immunol
Title: Single-cell RNA sequencing reveals evolution of immune landscape during glioblastoma progression.
Volume: 23
Issue: 6
Pages: 971-984
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Publication
26637667 | J:237661
First Author: Lastwika KJ
Year: 2016
Journal: Cancer Res
Title: Control of PD-L1 Expression by Oncogenic Activation of the AKT-mTOR Pathway in Non-Small Cell Lung Cancer.
Volume: 76
Issue: 2
Pages: 227-38
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Publication
23532334 | J:259987
First Author: Bean GR
Year: 2013
Journal: Sci Signal
Title: PUMA and BIM are required for oncogene inactivation-induced apoptosis.
Volume: 6
Issue: 268
Pages: ra20
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Publication
12917378 | -
First Author: Ou XM
Year: 2003
Journal: J Neurosci
Title: Freud-1: A neuronal calcium-regulated repressor of the 5-HT1A receptor gene.
Volume: 23
Issue: 19
Pages: 7415-25
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Publication
16033914 | J:200890
First Author: Basel-Vanagaite L
Year: 2006
Journal: J Med Genet
Title: The CC2D1A, a member of a new gene family with C2 domains, is involved in autosomal recessive non-syndromic mental retardation.
Volume: 43
Issue: 3
Pages: 203-10
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Protein
Q3V2Z9
Organism: Mus musculus/domesticus
Length: 70  
Fragment?: true
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Protein
Q3V475
Organism: Mus musculus/domesticus
Length: 94  
Fragment?: true
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Publication
17535813 | J:124603
First Author: Rogaeva A
Year: 2007
Journal: J Biol Chem
Title: Differential repression by freud-1/CC2D1A at a polymorphic site in the dopamine-D2 receptor gene.
Volume: 282
Issue: 29
Pages: 20897-905
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Publication
17394259 | -
First Author: Rogaeva A
Year: 2007
Journal: J Neurosci Res
Title: The Freud-1/CC2D1A family: transcriptional regulators implicated in mental retardation.
Volume: 85
Issue: 13
Pages: 2833-8
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Publication
27013495 | J:235307
First Author: Weber A
Year: 2016
Journal: EMBO Rep
Title: The deubiquitinase Usp27x stabilizes the BH3-only protein Bim and enhances apoptosis.
Volume: 17
Issue: 5
Pages: 724-38
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Publication
17182860 | J:123889
First Author: Shen F
Year: 2007
Journal: Mol Biol Cell
Title: Activated Cdc42-associated kinase 1 is a component of EGF receptor signaling complex and regulates EGF receptor degradation.
Volume: 18
Issue: 3
Pages: 732-42
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Publication
20086093 | J:170793
First Author: Lin Q
Year: 2010
Journal: Mol Cell Biol
Title: HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACK.
Volume: 30
Issue: 6
Pages: 1541-54
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Publication
19725050 | J:160043
First Author: Ng EL
Year: 2009
Journal: J Cell Physiol
Title: Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells.
Volume: 221
Issue: 3
Pages: 716-28
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Publication
12802020 | J:224743
First Author: Lu Q
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation.
Volume: 100
Issue: 13
Pages: 7626-31
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Publication
1765103 | J:2328
First Author: Mizuno K
Year: 1991
Journal: Eur J Biochem
Title: Structure and properties of a ubiquitously expressed protein kinase C, nPKC delta.
Volume: 202
Issue: 3
Pages: 931-40
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Publication
23418353 | J:213100
First Author: Smith CJ
Year: 2013
Journal: J Cell Sci
Title: The E3 ubiquitin ligases RNF126 and Rabring7 regulate endosomal sorting of the epidermal growth factor receptor.
Volume: 126
Issue: Pt 6
Pages: 1366-80
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Publication
12890790 | J:84682
First Author: Li SH
Year: 2003
Journal: J Neurosci
Title: Lack of huntingtin-associated protein-1 causes neuronal death resembling hypothalamic degeneration in Huntington's disease.
Volume: 23
Issue: 17
Pages: 6956-64
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Publication
7689153 | J:29845
First Author: Fazioli F
Year: 1993
Journal: Mol Cell Biol
Title: eps15, a novel tyrosine kinase substrate, exhibits transforming activity.
Volume: 13
Issue: 9
Pages: 5814-28
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Publication
8404850 | J:34029
First Author: Fazioli F
Year: 1993
Journal: EMBO J
Title: Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals.
Volume: 12
Issue: 10
Pages: 3799-808
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Publication
19956733 | J:161749
First Author: Mill P
Year: 2009
Journal: PLoS Genet
Title: Palmitoylation regulates epidermal homeostasis and hair follicle differentiation.
Volume: 5
Issue: 11
Pages: e1000748
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Publication
21419809 | J:175007
First Author: Woller B
Year: 2011
Journal: Biochim Biophys Acta
Title: Rin-like, a novel regulator of endocytosis, acts as guanine nucleotide exchange factor for Rab5a and Rab22.
Volume: 1813
Issue: 6
Pages: 1198-210
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Publication
20361963 | J:162344
First Author: Kioka N
Year: 2010
Journal: Exp Cell Res
Title: Crucial role of vinexin for keratinocyte migration in vitro and epidermal wound healing in vivo.
Volume: 316
Issue: 10
Pages: 1728-38
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Publication
24691449 | J:215040
First Author: Fullár A
Year: 2014
Journal: PLoS One
Title: Lack of Matrilin-2 favors liver tumor development via Erk1/2 and GSK-3β pathways in vivo.
Volume: 9
Issue: 4
Pages: e93469
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Publication
21406403 | J:169919
First Author: Hafeez BB
Year: 2011
Journal: Cancer Res
Title: Genetic ablation of PKC epsilon inhibits prostate cancer development and metastasis in transgenic mouse model of prostate adenocarcinoma.
Volume: 71
Issue: 6
Pages: 2318-27
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Publication
28655773 | J:245821
First Author: Li S
Year: 2017
Journal: J Biol Chem
Title: Ectodysplasin A protein promotes corneal epithelial cell proliferation.
Volume: 292
Issue: 32
Pages: 13391-13401
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Publication
36874012 | J:345155
 
First Author: Li X
Year: 2023
Journal: Front Pharmacol
Title: YY1-induced upregulation of LncRNA-ARAP1-AS2 and ARAP1 promotes diabetic kidney fibrosis via aberrant glycolysis associated with EGFR/PKM2/HIF-1α pathway.
Volume: 14
Pages: 1069348
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Publication
37288304 | J:346923
 
First Author: Schürfeld R
Year: 2023
Journal: Front Endocrinol (Lausanne)
Title: Renal function is a major predictor of circulating acyl-CoA-binding protein/diazepam-binding inhibitor.
Volume: 14
Pages: 1152444
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Publication
28319060 | J:243362
First Author: Zhou M
Year: 2017
Journal: Oncogene
Title: The anti-diabetic drug exenatide, a glucagon-like peptide-1 receptor agonist, counteracts hepatocarcinogenesis through cAMP-PKA-EGFR-STAT3 axis.
Volume: 36
Issue: 29
Pages: 4135-4149
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Publication
29182680 | J:254176
First Author: Ahrens JM
Year: 2017
Journal: PLoS One
Title: Differential activity of 2-methylene-19-nor vitamin D analogs on growth factor gene expression in rhino mouse skin and comparison to all-trans retinoic acid.
Volume: 12
Issue: 11
Pages: e0188887
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Publication
26038598 | J:260210
First Author: Mancini M
Year: 2015
Journal: Sci Signal
Title: Combining three antibodies nullifies feedback-mediated resistance to erlotinib in lung cancer.
Volume: 8
Issue: 379
Pages: ra53
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Publication
28096505 | J:260292
 
First Author: Gemmill RM
Year: 2017
Journal: Sci Signal
Title: The neuropilin 2 isoform NRP2b uniquely supports TGFβ-mediated progression in lung cancer.
Volume: 10
Issue: 462
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Publication
15292206 | J:93986
First Author: Zhao L
Year: 2004
Journal: J Biol Chem
Title: Mammary gland remodeling depends on gp130 signaling through Stat3 and MAPK.
Volume: 279
Issue: 42
Pages: 44093-100
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Publication
24708244 | J:214266
First Author: Collin de l'Hortet A
Year: 2014
Journal: Endocrinology
Title: GH administration rescues fatty liver regeneration impairment by restoring GH/EGFR pathway deficiency.
Volume: 155
Issue: 7
Pages: 2545-54
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Publication
35478031 | J:341603
First Author: Pellegrinelli V
Year: 2022
Journal: Nat Metab
Title: Dysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance.
Volume: 4
Issue: 4
Pages: 476-494
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Publication
30111646 | J:264376
 
First Author: Shipman WD
Year: 2018
Journal: Sci Transl Med
Title: A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivity.
Volume: 10
Issue: 454
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Publication
29312533 | J:309223
First Author: Dombernowsky SL
Year: 2017
Journal: Oncotarget
Title: Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the ApcMin model of colorectal cancer.
Volume: 8
Issue: 65
Pages: 108303-108315
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Publication
20473900 | J:167346
First Author: Nautiyal J
Year: 2011
Journal: Int J Cancer
Title: Curcumin enhances dasatinib-induced inhibition of growth and transformation of colon cancer cells.
Volume: 128
Issue: 4
Pages: 951-61
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Publication
26503053 | J:226759
First Author: Gregorieff A
Year: 2015
Journal: Nature
Title: Yap-dependent reprogramming of Lgr5(+) stem cells drives intestinal regeneration and cancer.
Volume: 526
Issue: 7575
Pages: 715-8
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Publication
27207671 | J:232780
First Author: Tao Y
Year: 2016
Journal: Carcinogenesis
Title: Hsp70 exerts oncogenic activity in the Apc mutant Min mouse model.
Volume: 37
Issue: 7
Pages: 731-739
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Publication
30022999 | J:275895
 
First Author: Hosur V
Year: 2018
Journal: Front Genet
Title: RHBDF2-Regulated Growth Factor Signaling in a Rare Human Disease, Tylosis With Esophageal Cancer: What Can We Learn From Murine Models?
Volume: 9
Pages: 233
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Publication
31237864 | J:297143
   
First Author: Gbenedio OM
Year: 2019
Journal: JCI Insight
Title: RasGRP1 is a potential biomarker to stratify anti-EGFR therapy response in colorectal cancer.
Volume: 5
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Publication
24788409 | J:211668
First Author: Cordero JB
Year: 2014
Journal: EMBO J
Title: c-Src drives intestinal regeneration and transformation.
Volume: 33
Issue: 13
Pages: 1474-91
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Publication
19690388 | J:152703
First Author: Lee D
Year: 2009
Journal: J Clin Invest
Title: Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium.
Volume: 119
Issue: 9
Pages: 2702-13
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Publication
31036568 | J:291744
 
First Author: Cramer ML
Year: 2019
Journal: Mol Cell Biol
Title: Soluble Heparin Binding Epidermal Growth Factor-Like Growth Factor Is a Regulator of GALGT2 Expression and GALGT2-Dependent Muscle and Neuromuscular Phenotypes.
Volume: 39
Issue: 14
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Publication
37758009 | J:342144
 
First Author: Zhang H
Year: 2023
Journal: Dev Biol
Title: Tenascin-C-EGFR activation induces functional human satellite cell proliferation and promotes wound-healing of skeletal muscles via oleanic acid.
Volume: 504
Pages: 86-97
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Publication
15994019 | J:104427
First Author: Koshibu K
Year: 2005
Journal: Neuroscience
Title: Sex differences in expression of transforming growth factor-alpha and epidermal growth factor receptor mRNA in Waved-1 and C57Bl6 mice.
Volume: 134
Issue: 3
Pages: 877-87
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Publication
16857964 | J:124859
First Author: Lemarié CA
Year: 2006
Journal: Circ Res
Title: Transforming growth factor-alpha mediates nuclear factor kappaB activation in strained arteries.
Volume: 99
Issue: 4
Pages: 434-41
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Publication
20921623 | J:166941
First Author: Viau A
Year: 2010
Journal: J Clin Invest
Title: Lipocalin 2 is essential for chronic kidney disease progression in mice and humans.
Volume: 120
Issue: 11
Pages: 4065-76
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Publication
25573952 | J:220187
First Author: Yallowitz AR
Year: 2015
Journal: Mol Cancer Res
Title: Mutant p53 Amplifies Epidermal Growth Factor Receptor Family Signaling to Promote Mammary Tumorigenesis.
Volume: 13
Issue: 4
Pages: 743-54
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Publication
20861192 | J:166081
First Author: Hochgräfe F
Year: 2010
Journal: Cancer Res
Title: Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells.
Volume: 70
Issue: 22
Pages: 9391-401
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Publication
35923856 | J:327152
 
First Author: Sano M
Year: 2022
Journal: Front Cell Dev Biol
Title: Neutrophil extracellular traps-mediated Beclin-1 suppression aggravates atherosclerosis by inhibiting macrophage autophagy.
Volume: 10
Pages: 876147
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Publication
22573379 | J:187019
First Author: Blaes N
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Bradykinin inhibits high glucose- and growth factor-induced collagen synthesis in mesangial cells through the B2-kinin receptor.
Volume: 303
Issue: 2
Pages: F293-303
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Publication
17827153 | J:126817
First Author: Li T
Year: 2007
Journal: J Biol Chem
Title: Epidermal growth factor receptor and notch pathways participate in the tumor suppressor function of gamma-secretase.
Volume: 282
Issue: 44
Pages: 32264-73
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Publication
34088769 | J:321743
First Author: Dustin CM
Year: 2021
Journal: J Immunol
Title: Oxidation-Dependent Activation of Src Kinase Mediates Epithelial IL-33 Production and Signaling during Acute Airway Allergen Challenge.
Volume: 206
Issue: 12
Pages: 2989-2999
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Publication
28446616 | J:242217
First Author: Harder JM
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective.
Volume: 114
Issue: 19
Pages: E3839-E3848
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Publication
36241718 | J:339253
First Author: Cheng R
Year: 2023
Journal: Cell Res
Title: A novel protein RASON encoded by a lncRNA controls oncogenic RAS signaling in KRAS mutant cancers.
Volume: 33
Issue: 1
Pages: 30-45
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Publication
9851974 | J:52161
First Author: Holland EC
Year: 1998
Journal: Genes Dev
Title: A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice.
Volume: 12
Issue: 23
Pages: 3675-85
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Publication
21566664 | J:201800
First Author: Liu B
Year: 2011
Journal: Cell Death Differ
Title: IKKα represses a network of inflammation and proliferation pathways and elevates c-Myc antagonists and differentiation in a dose-dependent manner in the skin.
Volume: 18
Issue: 12
Pages: 1854-64
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Publication
22891331 | J:188576
First Author: Fenton TR
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240.
Volume: 109
Issue: 35
Pages: 14164-9
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Publication
21975932 | J:178004
First Author: Jin X
Year: 2011
Journal: Cancer Res
Title: EGFR-AKT-Smad signaling promotes formation of glioma stem-like cells and tumor angiogenesis by ID3-driven cytokine induction.
Volume: 71
Issue: 22
Pages: 7125-34
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Publication
10669005 | J:60497
First Author: Holland EC
Year: 2000
Journal: Toxicol Pathol
Title: A mouse model for glioma: biology, pathology, and therapeutic opportunities.
Volume: 28
Issue: 1
Pages: 171-7
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Publication
22792392 | J:189640
First Author: Trierweiler C
Year: 2012
Journal: PLoS One
Title: The transcription factor c-Jun protects against liver damage following activated β-Catenin signaling.
Volume: 7
Issue: 7
Pages: e40638
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Publication
17079736 | J:121009
First Author: Horiuchi K
Year: 2007
Journal: Mol Biol Cell
Title: Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx.
Volume: 18
Issue: 1
Pages: 176-88
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Publication
21454669 | J:172250
First Author: Yoon S
Year: 2011
Journal: J Biol Chem
Title: Wnt5a-dopamine D2 receptor interactions regulate dopamine neuron development via extracellular signal-regulated kinase (ERK) activation.
Volume: 286
Issue: 18
Pages: 15641-51
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Publication
18054559 | J:135620
First Author: Fukata M
Year: 2007
Journal: Gastroenterology
Title: Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors.
Volume: 133
Issue: 6
Pages: 1869-81
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Publication
17369357 | J:120116
First Author: Ciarloni L
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Amphiregulin is an essential mediator of estrogen receptor alpha function in mammary gland development.
Volume: 104
Issue: 13
Pages: 5455-60
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Publication
20675406 | J:163257
First Author: Benhamouche S
Year: 2010
Journal: Genes Dev
Title: Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver.
Volume: 24
Issue: 16
Pages: 1718-30
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Publication
16020518 | J:169659
First Author: Means AL
Year: 2005
Journal: Development
Title: Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates.
Volume: 132
Issue: 16
Pages: 3767-76
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Publication
23867472 | J:204282
First Author: Yin Y
Year: 2013
Journal: Cancer Res
Title: Rapid induction of lung adenocarcinoma by fibroblast growth factor 9 signaling through FGF receptor 3.
Volume: 73
Issue: 18
Pages: 5730-41
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Publication
37344586 | J:340082
First Author: Gallini S
Year: 2023
Journal: Nature
Title: Injury prevents Ras mutant cell expansion in mosaic skin.
Volume: 619
Issue: 7968
Pages: 167-175
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Publication
24177178 | J:206603
First Author: Lee CY
Year: 2014
Journal: Cancer Res
Title: Neuregulin autocrine signaling promotes self-renewal of breast tumor-initiating cells by triggering HER2/HER3 activation.
Volume: 74
Issue: 1
Pages: 341-52
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Publication
10331984 | J:54980
First Author: Luetteke NC
Year: 1999
Journal: Development
Title: Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development.
Volume: 126
Issue: 12
Pages: 2739-50
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Publication
21097655 | J:186821
First Author: Shiomi T
Year: 2011
Journal: Am J Respir Cell Mol Biol
Title: TNF-α-converting enzyme/a disintegrin and metalloprotease-17 mediates mechanotransduction in murine tracheal epithelial cells.
Volume: 45
Issue: 2
Pages: 376-85
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Publication
17484876 | J:128324
First Author: Nam KT
Year: 2007
Journal: Gastroenterology
Title: Potentiation of oxyntic atrophy-induced gastric metaplasia in amphiregulin-deficient mice.
Volume: 132
Issue: 5
Pages: 1804-19
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Publication
10931950 | J:64071
First Author: Lenferink AE
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu + MMTV/TGF-alpha bigenic mice.
Volume: 97
Issue: 17
Pages: 9609-14
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Publication
25772240 | J:314977
First Author: Park JM
Year: 2015
Journal: Oncogene
Title: The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis.
Volume: 34
Issue: 50
Pages: 6105-14
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Publication
22347416 | J:185233
First Author: Kim S
Year: 2012
Journal: PLoS One
Title: A phenotypic mouse model of basaloid breast tumors.
Volume: 7
Issue: 2
Pages: e30979
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Publication
8816486 | J:35344
First Author: Muller WJ
Year: 1996
Journal: Mol Cell Biol
Title: Synergistic interaction of the Neu proto-oncogene product and transforming growth factor alpha in the mammary epithelium of transgenic mice.
Volume: 16
Issue: 10
Pages: 5726-36
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Publication
32672423 | J:336897
First Author: Zecchin D
Year: 2020
Journal: EMBO Mol Med
Title: Combined targeting of G protein-coupled receptor and EGF receptor signaling overcomes resistance to PI3K pathway inhibitors in PTEN-null triple negative breast cancer.
Volume: 12
Issue: 8
Pages: e11987
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Publication
30733286 | J:272888
First Author: Kubli SP
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer.
Volume: 116
Issue: 9
Pages: 3604-3613
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Publication
27888617 | J:316145
First Author: Lee SH
Year: 2016
Journal: Oncotarget
Title: Suppression of osteopontin inhibits chemically induced hepatic carcinogenesis by induction of apoptosis in mice.
Volume: 7
Issue: 52
Pages: 87219-87231
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Publication
23348744 | J:194483
First Author: Issuree PD
Year: 2013
Journal: J Clin Invest
Title: iRHOM2 is a critical pathogenic mediator of inflammatory arthritis.
Volume: 123
Issue: 2
Pages: 928-32
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Publication
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