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Search results 2201 to 2300 out of 2705 for Foxp3

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Type Details Score
Genotype
Genotype
Symbol: Foxp3/Foxp3<+> Il1r2/Il1r2
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * C57BL/6NTac
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pgd/Pgd Foxp3/Foxp3<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Foxp3/Foxp3<+>
Background: B6.129X1-Foxp3
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Foxp3/Foxp3<+>
Background: B6.Cg-Foxp3/J
Zygosity: ht
Has Mutant Allele: true
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Publication
33027660 | J:304323
First Author: Browning LM
Year: 2020
Journal: Cell Rep
Title: Bone Morphogenic Proteins Are Immunoregulatory Cytokines Controlling FOXP3+ Treg Cells.
Volume: 33
Issue: 1
Pages: 108219
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Publication
21712997 | J:174435
First Author: Schmutz I
Year: 2011
Journal: PLoS One
Title: Protein phosphatase 1 (PP1) is a post-translational regulator of the mammalian circadian clock.
Volume: 6
Issue: 6
Pages: e21325
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Publication
20516061 | J:168381
First Author: Lee JH
Year: 2010
Journal: J Biol Chem
Title: Identification and characterization of a novel human PP1 phosphatase complex.
Volume: 285
Issue: 32
Pages: 24466-76
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Publication
15124925 | -
First Author: Ito M
Year: 2004
Journal: Mol Cell Biochem
Title: Myosin phosphatase: structure, regulation and function.
Volume: 259
Issue: 1-2
Pages: 197-209
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Publication
20354225 | -
First Author: Zagórska A
Year: 2010
Journal: Sci Signal
Title: New roles for the LKB1-NUAK pathway in controlling myosin phosphatase complexes and cell adhesion.
Volume: 3
Issue: 115
Pages: ra25
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Publication
1651919 | -
First Author: Tang PM
Year: 1991
Journal: J Biol Chem
Title: Molecular cloning and expression of the regulatory (RG1) subunit of the glycogen-associated protein phosphatase.
Volume: 266
Issue: 24
Pages: 15782-9
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Publication
12226088 | -
First Author: Ceulemans H
Year: 2002
Journal: J Biol Chem
Title: Binding of the concave surface of the Sds22 superhelix to the alpha 4/alpha 5/alpha 6-triangle of protein phosphatase-1.
Volume: 277
Issue: 49
Pages: 47331-7
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Publication
11564868 | -
First Author: Connor JH
Year: 2001
Journal: Mol Cell Biol
Title: Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1.
Volume: 21
Issue: 20
Pages: 6841-50
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Publication
17283141 | -
First Author: Mi J
Year: 2007
Journal: Cancer Res
Title: Protein phosphatase-1alpha regulates centrosome splitting through Nek2.
Volume: 67
Issue: 3
Pages: 1082-9
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Publication
26083323 | -
First Author: Song H
Year: 2015
Journal: Autophagy
Title: ATG16L1 phosphorylation is oppositely regulated by CSNK2/casein kinase 2 and PPP1/protein phosphatase 1 which determines the fate of cardiomyocytes during hypoxia/reoxygenation.
Volume: 11
Issue: 8
Pages: 1308-25
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Publication
38499786 | J:348950
First Author: Wu Q
Year: 2024
Journal: EMBO J
Title: Ferritin heavy chain supports stability and function of the regulatory T cell lineage.
Volume: 43
Issue: 8
Pages: 1445-1483
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Publication
27062243 | J:246794
First Author: Edwards JP
Year: 2016
Journal: Eur J Immunol
Title: The GARP/Latent TGF-β1 complex on Treg cells modulates the induction of peripherally derived Treg cells during oral tolerance.
Volume: 46
Issue: 6
Pages: 1480-9
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Publication
32072192 | J:289539
First Author: Zhang J
Year: 2020
Journal: Diabetologia
Title: Extracellular HMGB1 exacerbates autoimmune progression and recurrence of type 1 diabetes by impairing regulatory T cell stability.
Volume: 63
Issue: 5
Pages: 987-1001
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Protein Domain
IPR037981 | PPP1CC
Type: Family
Description: Serine/threonine-protein phosphatase PP1 () is a complex of a catalytic subunit, either PPP1CA, PPP1CB or PPP1CC, with one or more regulatory or targeting subunits. Example targeting subunits are PPP1R12A and PPP1R12C, which mediate binding of PP1 to myosin [, , ]; PPP1R3A, which mediates binding to glycogen in the skeletal muscle []; PPP1R7, []; PPP1R15A, which mediates binding to EIF2S1 []. The phosphatase associates with any one of many other regulatory proteins to form a complex that dephosphorylates a specific target protein. For example, centrosome splitting is regulated by the association of NEK2 with PP1 via the PPP1CA subunit [], binding to ATG16L1 antagonizes casein kinase 2-mediated phosphorylation of ATG16L1 affecting the fate of cadiomyocytes []and association with TNF-a induces phosphorylation of FOXP3 which controls regulatory T cell function []. PP1 is required for the cell cycle [], cell division, glycogen metabolism [], muscle contraction []and protein synthesis. PPP1CA and PPP1CB are components of the PTW/PP1 phosphatase complex [].This entry includes the catalytic subunit gamma (PPP1CC) from mammals, Dis2 from fission yeasts and Glc7 from budding yeasts. Glc7 is also a component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB [].
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Protein Domain
IPR037979 | PPP1CA
Type: Family
Description: Serine/threonine-protein phosphatase PP1 () is a complex of a catalytic subunit, either PPP1CA, PPP1CB or PPP1CC, with one or more regulatory or targeting subunits. Example targeting subunits are PPP1R12A and PPP1R12C, which mediate binding of PP1 to myosin [, , ]; PPP1R3A, which mediates binding to glycogen in the skeletal muscle []; PPP1R7, []; PPP1R15A, which mediates binding to EIF2S1 []. The phosphatase associates with any one of many other regulatory proteins to form a complex that dephosphorylates a specific target protein. For example, centrosome splitting is regulated by the association of NEK2 with PP1 via the PPP1CA subunit [], binding to ATG16L1 antagonizes casein kinase 2-mediated phosphorylation of ATG16L1 affecting the fate of cadiomyocytes []and association with TNF-a induces phosphorylation of FOXP3 which controls regulatory T cell function []. PP1 is required for the cell cycle [], cell division, glycogen metabolism [], muscle contraction []and protein synthesis. PPP1CA and PPP1CB are components of the PTW/PP1 phosphatase complex [].This entry includes the catalytic subunits PP1-alpha (PPP1CA).
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Strain
MGI:6348331 | NOD.Cg-Ighm<tm1Cgn> H2<h4> Tg(Foxp3-HBEGF/EGFP)1Doi/HbmMmmh
Attribute String: targeted mutation, congenic, mutant strain, transgenic
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Publication
26573835 | J:336822
First Author: Ehrlich AK
Year: 2016
Journal: J Immunol
Title: Activation of the Aryl Hydrocarbon Receptor by 10-Cl-BBQ Prevents Insulitis and Effector T Cell Development Independently of Foxp3+ Regulatory T Cells in Nonobese Diabetic Mice.
Volume: 196
Issue: 1
Pages: 264-73
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Strain
MGI:6759400 | B6.Cg-Tnfrsf18<tm1.1(TNFRSF18)Geno> Foxp3<tm1Flv>/Geno
Attribute String: congenic, mutant strain, targeted mutation
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Allele
Foxp3<tm3Tch> | MGI:3707723
Name: forkhead box P3; targeted mutation 3, Talal A Chatila
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Strain
MGI:5545651 | C57BL/6-Tg(Foxp3-GFP)90Pkraj/J
Attribute String: coisogenic, mutant strain, transgenic
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Publication
30532264 | J:268086
First Author: Magallanes-Puebla A
Year: 2018
Journal: PLoS One
Title: Mycobacterial glycolipid Di-O-acyl trehalose promotes a tolerogenic profile in dendritic cells.
Volume: 13
Issue: 12
Pages: e0207202
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Publication
31776355 | J:287612
First Author: Kannan AK
Year: 2019
Journal: Sci Rep
Title: IL-23 induces regulatory T cell plasticity with implications for inflammatory skin diseases.
Volume: 9
Issue: 1
Pages: 17675
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Strain
MGI:6865880 | STOCK Foxp3<tm4(icre)Tch>/Mmjax
Attribute String: targeted mutation, mutant stock
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Genotype
Genotype
Symbol: Foxp3/?
Background: involves: BALB/c
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Foxp3/? Il6/Il6
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Foxp3/Foxp3<+> Gpr174/Gpr174<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Publication
11399775 | -
First Author: Tan I
Year: 2001
Journal: J Biol Chem
Title: Phosphorylation of a novel myosin binding subunit of protein phosphatase 1 reveals a conserved mechanism in the regulation of actin cytoskeleton.
Volume: 276
Issue: 24
Pages: 21209-16
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Publication
18505825 | J:137911
First Author: Hoser M
Year: 2008
Journal: Mol Cell Biol
Title: Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors.
Volume: 28
Issue: 15
Pages: 4675-87
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Publication
17641007 | J:149955
First Author: So T
Year: 2007
Journal: J Immunol
Title: Cutting edge: OX40 inhibits TGF-beta- and antigen-driven conversion of naive CD4 T cells into CD25+Foxp3+ T cells.
Volume: 179
Issue: 3
Pages: 1427-30
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Publication
30696265 | J:280008
First Author: Wang Y
Year: 2019
Journal: Circulation
Title: C-X-C Motif Chemokine Receptor 4 Blockade Promotes Tissue Repair After Myocardial Infarction by Enhancing Regulatory T Cell Mobilization and Immune-Regulatory Function.
Volume: 139
Issue: 15
Pages: 1798-1812
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Publication
21292811 | J:171004
First Author: Stagg J
Year: 2011
Journal: Cancer Res
Title: CD73-deficient mice have increased antitumor immunity and are resistant to experimental metastasis.
Volume: 71
Issue: 8
Pages: 2892-900
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Publication
29864157 | J:262840
First Author: Deshpande NR
Year: 2018
Journal: PLoS One
Title: A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice.
Volume: 13
Issue: 6
Pages: e0198354
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Strain
MGI:3708174 | C.129X1-Foxp3<tm3Tch>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5476697 | C.129X1-Foxp3<tm3Tch>/J
Attribute String: congenic, mutant strain, targeted mutation
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Allele
Tg(Foxp3-EGFP/cre)1cJbs | MGI:3809724
Name: transgene insertion 1c, Jeffrey Bluestone
Allele Type: Transgenic
Attribute String: Recombinase
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Strain
MGI:4843469 | C.B6-Tg(Foxp3-HBEGF/EGFP)23.2Spar/Mmjax
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:4429460 | C57BL/6-Tg(Foxp3-HBEGF/EGFP)23.2Spar/Mmjax
Attribute String: coisogenic, mutant strain, transgenic
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Publication
33452272 | J:300563
First Author: Hartmann W
Year: 2021
Journal: Sci Rep
Title: Elucidating different pattern of immunoregulation in BALB/c and C57BL/6 mice and their F1 progeny.
Volume: 11
Issue: 1
Pages: 1536
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Publication
30410119 | J:268102
First Author: Galdino NAL
Year: 2018
Journal: Sci Rep
Title: Depletion of regulatory T cells in ongoing paracoccidioidomycosis rescues protective Th1/Th17 immunity and prevents fatal disease outcome.
Volume: 8
Issue: 1
Pages: 16544
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Publication
23071726 | J:192084
First Author: Baru AM
Year: 2012
Journal: PLoS One
Title: Absence of Foxp3+ regulatory T cells during allergen provocation does not exacerbate murine allergic airway inflammation.
Volume: 7
Issue: 10
Pages: e47102
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Publication
31755554 | J:285761
First Author: Kehrmann J
Year: 2020
Journal: Immunology
Title: Depletion of Foxp3+ regulatory T cells is accompanied by an increase in the relative abundance of Firmicutes in the murine gut microbiome.
Volume: 159
Issue: 3
Pages: 344-353
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Publication
33826741 | J:348440
First Author: Clark PA
Year: 2021
Journal: Radiat Res
Title: Low-Dose Radiation Potentiates the Propagation of Anti-Tumor Immunity against Melanoma Tumor in the Brain after In Situ Vaccination at a Tumor outside the Brain.
Volume: 195
Issue: 6
Pages: 522-540
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Publication
25286182 | J:223468
First Author: Meyer zu Hörste G
Year: 2014
Journal: PLoS One
Title: FoxP3+ regulatory T cells determine disease severity in rodent models of inflammatory neuropathies.
Volume: 9
Issue: 10
Pages: e108756
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Publication
27834288 | J:350194
First Author: Heitmann RJ
Year: 2017
Journal: Reprod Sci
Title: Maternal T Regulatory Cell Depletion Impairs Embryo Implantation Which Can Be Corrected With Adoptive T Regulatory Cell Transfer.
Volume: 24
Issue: 7
Pages: 1014-1024
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Publication
19671923 | J:153544
First Author: Zelinskyy G
Year: 2009
Journal: Blood
Title: The regulatory T-cell response during acute retroviral infection is locally defined and controls the magnitude and duration of the virus-specific cytotoxic T-cell response.
Volume: 114
Issue: 15
Pages: 3199-207
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Publication
32778610 | J:354100
 
First Author: Siebers EM
Year: 2020
Journal: Infect Immun
Title: Regulatory T Cells Contribute to Resistance against Lyme Arthritis.
Volume: 88
Issue: 11
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Publication
32213566 | J:288581
First Author: Moyé S
Year: 2020
Journal: J Immunol
Title: Regulatory T Cells Limit Pneumococcus-Induced Exacerbation of Lung Fibrosis in Mice.
Volume: 204
Issue: 9
Pages: 2429-2438
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Publication
34675812 | J:348442
 
First Author: Kurelic R
Year: 2021
Journal: Front Pharmacol
Title: Upregulation of Phosphodiesterase 2A Augments T Cell Activation by Changing cGMP/cAMP Cross-Talk.
Volume: 12
Pages: 748798
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Publication
30651334 | J:275854
First Author: Duffy SS
Year: 2019
Journal: J Neurosci
Title: Regulatory T Cells and Their Derived Cytokine, Interleukin-35, Reduce Pain in Experimental Autoimmune Encephalomyelitis.
Volume: 39
Issue: 12
Pages: 2326-2346
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Publication
23007132 | J:190336
First Author: Goldwich A
Year: 2012
Journal: Lab Invest
Title: Impairment of podocyte function by diphtheria toxin--a new reversible proteinuria model in mice.
Volume: 92
Issue: 12
Pages: 1674-85
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Publication
38177096 | J:346008
First Author: Zamora A
Year: 2024
Journal: Nat Commun
Title: 15-Lipoxygenase promotes resolution of inflammation in lymphedema by controlling T(reg) cell function through IFN-β.
Volume: 15
Issue: 1
Pages: 221
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Publication
32690669 | J:348437
 
First Author: Clark PA
Year: 2020
Journal: J Immunother Cancer
Title: In situ vaccination at a peripheral tumor site augments response against melanoma brain metastases.
Volume: 8
Issue: 2
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Publication
26986976 | J:259762
First Author: Dietze KK
Year: 2016
Journal: PLoS One
Title: Characterization of the Treg Response in the Hepatitis B Virus Hydrodynamic Injection Mouse Model.
Volume: 11
Issue: 3
Pages: e0151717
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Publication
26711629 | J:246644
First Author: Win SJ
Year: 2016
Journal: Eur J Immunol
Title: In vivo activation of Treg cells with a CD28 superagonist prevents and ameliorates chronic destructive arthritis in mice.
Volume: 46
Issue: 5
Pages: 1193-202
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Publication
37092551 | J:347196
 
First Author: Sumii Y
Year: 2023
Journal: JCI Insight
Title: Hematopoietic stem cell-derived Tregs are essential for maintaining favorable B cell lymphopoiesis following posttransplant cyclophosphamide.
Volume: 8
Issue: 8
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Publication
30425092 | J:353128
First Author: Suryadevara CM
Year: 2019
Journal: Clin Cancer Res
Title: Preventing Lck Activation in CAR T Cells Confers Treg Resistance but Requires 4-1BB Signaling for Them to Persist and Treat Solid Tumors in Nonlymphodepleted Hosts.
Volume: 25
Issue: 1
Pages: 358-368
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Publication
31336883 | J:353148
 
First Author: Baek H
Year: 2019
Journal: Toxins (Basel)
Title: Prophylactic Effects of Bee Venom Phospholipase A2 in Lipopolysaccharide-Induced Pregnancy Loss.
Volume: 11
Issue: 7
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Publication
36839461 | J:353154
 
First Author: Santiago KN
Year: 2023
Journal: Pathogens
Title: Effects of Regulatory T Cell Depletion in BALB/c Mice Infected with Low Doses of Borrelia burgdorferi.
Volume: 12
Issue: 2
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Publication
21742969 | J:179166
First Author: Mattarollo SR
Year: 2011
Journal: J Immunol
Title: NKT cells inhibit antigen-specific effector CD8 T cell induction to skin viral proteins.
Volume: 187
Issue: 4
Pages: 1601-8
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Publication
35061693 | J:322519
First Author: Yu F
Year: 2022
Journal: PLoS One
Title: Rational construction of controllable autoimmune diabetes model depicting clinical features.
Volume: 17
Issue: 1
Pages: e0260100
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Publication
30782087 | J:353144
First Author: Royster GD
Year: 2019
Journal: Reprod Sci
Title: Rapamycin Corrects T Regulatory Cell Depletion and Improves Embryo Implantation and Live Birth Rates in a Murine Model.
Volume: 26
Issue: 12
Pages: 1545-1556
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Publication
31804466 | J:283920
First Author: Wang Z
Year: 2019
Journal: Nat Commun
Title: Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4.
Volume: 10
Issue: 1
Pages: 5546
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Publication
23129753 | J:190970
First Author: Veiga-Parga T
Year: 2012
Journal: J Immunol
Title: On the role of regulatory T cells during viral-induced inflammatory lesions.
Volume: 189
Issue: 12
Pages: 5924-33
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Publication
28035902 | J:239541
   
First Author: Fuhrmann F
Year: 2016
Journal: Elife
Title: Adequate immune response ensured by binary IL-2 and graded CD25 expression in a murine transfer model.
Volume: 5
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Publication
32156780 | J:289112
First Author: Ji L
Year: 2020
Journal: Cancer Res
Title: Blockade of β-Catenin-Induced CCL28 Suppresses Gastric Cancer Progression via Inhibition of Treg Cell Infiltration.
Volume: 80
Issue: 10
Pages: 2004-2016
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Publication
32939327 | J:349595
First Author: Wang C
Year: 2020
Journal: Oncoimmunology
Title: β-Catenin inhibition shapes tumor immunity and synergizes with immunotherapy in colorectal cancer.
Volume: 9
Issue: 1
Pages: 1809947
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Publication
29045819 | J:258434
First Author: Bruhs A
Year: 2018
Journal: J Invest Dermatol
Title: Disruption of the Epidermal Barrier Induces Regulatory T Cells via IL-33 in Mice.
Volume: 138
Issue: 3
Pages: 570-579
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Publication
24986517 | J:214243
First Author: Mittal D
Year: 2014
Journal: Cancer Res
Title: Antimetastatic effects of blocking PD-1 and the adenosine A2A receptor.
Volume: 74
Issue: 14
Pages: 3652-8
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Allele
Tg(Foxp3-EGFP/icre)1aJbs | MGI:4430213
Name: transgene insertion 1a, Jeffrey Bluestone
Allele Type: Transgenic
Attribute String: Recombinase
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Genotype
Genotype
Symbol: Foxp3/?
Background: C.129X1-Foxp3
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Foxp3/Foxp3<+>
Background: C.129X1-Foxp3
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctla4/Ctla4 Foxp3/?
Background: involves: BALB/c
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Foxp3-HBEGF/EGFP)23.2Spar/?
Background: involves: C57BL/6NCrl
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Foxp3/Foxp3<+> Tg(Zbtb20-EGFP)HZ275Gsat/?
Background: involves: C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
30513302 | J:306277
First Author: Becher J
Year: 2018
Journal: Dev Cell
Title: AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis.
Volume: 47
Issue: 5
Pages: 592-607.e6
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Publication
17307705 | J:118425
First Author: De Rosa V
Year: 2007
Journal: Immunity
Title: A key role of leptin in the control of regulatory T cell proliferation.
Volume: 26
Issue: 2
Pages: 241-55
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Publication
22942433 | J:190549
First Author: Koga T
Year: 2012
Journal: J Immunol
Title: Calcium/calmodulin-dependent protein kinase IV suppresses IL-2 production and regulatory T cell activity in lupus.
Volume: 189
Issue: 7
Pages: 3490-6
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Publication
28492364 | J:257150
   
First Author: Miao Y
Year: 2017
Journal: Elife
Title: Na+ influx via Orai1 inhibits intracellular ATP-induced mTORC2 signaling to disrupt CD4 T cell gene expression and differentiation.
Volume: 6
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Publication
28709804 | J:258941
First Author: Leonard JD
Year: 2017
Journal: Immunity
Title: Identification of Natural Regulatory T Cell Epitopes Reveals Convergence on a Dominant Autoantigen.
Volume: 47
Issue: 1
Pages: 107-117.e8
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Publication
38538608 | J:346725
First Author: Doglio M
Year: 2024
Journal: Nat Commun
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