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Search results 2201 to 2300 out of 3029 for Pdx1

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Type Details Score
Publication
32571902 | J:299302
 
First Author: Bangs FK
Year: 2020
Journal: Dis Model Mech
Title: Ciliogenesis and Hedgehog signalling are suppressed downstream of KRAS during acinar-ductal metaplasia in mouse.
Volume: 13
Issue: 7
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Publication
26477488 | J:231383
First Author: Vasseur R
Year: 2015
Journal: Biochim Biophys Acta
Title: The mucin MUC4 is a transcriptional and post-transcriptional target of K-ras oncogene in pancreatic cancer. Implication of MAPK/AP-1, NF-κB and RalB signaling pathways.
Volume: 1849
Issue: 12
Pages: 1375-84
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Publication
24909166 | J:221266
First Author: Kumar S
Year: 2015
Journal: Oncogene
Title: Smoking accelerates pancreatic cancer progression by promoting differentiation of MDSCs and inducing HB-EGF expression in macrophages.
Volume: 34
Issue: 16
Pages: 2052-60
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Publication
31923844 | J:311828
First Author: Gupta S
Year: 2020
Journal: Neoplasia
Title: Irreversible and sustained upregulation of endothelin axis during oncogene-associated pancreatic inflammation and cancer.
Volume: 22
Issue: 2
Pages: 98-110
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Publication
24209743 | J:205132
First Author: Jun S
Year: 2013
Journal: Cell Rep
Title: PAF-mediated MAPK signaling hyperactivation via LAMTOR3 induces pancreatic tumorigenesis.
Volume: 5
Issue: 2
Pages: 314-22
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Publication
21498546 | J:205226
First Author: Lee SH
Year: 2011
Journal: Mol Cancer Res
Title: The Id3/E47 axis mediates cell-cycle control in human pancreatic ducts and adenocarcinoma.
Volume: 9
Issue: 6
Pages: 782-90
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Publication
23828595 | J:199230
First Author: Lanza-Jacoby S
Year: 2013
Journal: Exp Biol Med (Maywood)
Title: Calorie restriction delays the progression of lesions to pancreatic cancer in the LSL-KrasG12D; Pdx-1/Cre mouse model of pancreatic cancer.
Volume: 238
Issue: 7
Pages: 787-97
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Publication
21159816 | J:166737
First Author: Kent OA
Year: 2010
Journal: Genes Dev
Title: Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway.
Volume: 24
Issue: 24
Pages: 2754-9
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Publication
22589274 | J:189307
First Author: Kelber JA
Year: 2012
Journal: Cancer Res
Title: KRas induces a Src/PEAK1/ErbB2 kinase amplification loop that drives metastatic growth and therapy resistance in pancreatic cancer.
Volume: 72
Issue: 10
Pages: 2554-64
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Publication
17652141 | J:123880
First Author: Funahashi H
Year: 2007
Journal: Cancer Res
Title: Delayed progression of pancreatic intraepithelial neoplasia in a conditional Kras(G12D) mouse model by a selective cyclooxygenase-2 inhibitor.
Volume: 67
Issue: 15
Pages: 7068-71
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Publication
27922049 | J:259562
 
First Author: Suh HN
Year: 2016
Journal: Sci Rep
Title: Identification of KIAA1199 as a Biomarker for Pancreatic Intraepithelial Neoplasia.
Volume: 6
Pages: 38273
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Publication
20484026 | J:160687
First Author: Hanlon L
Year: 2010
Journal: Cancer Res
Title: Notch1 functions as a tumor suppressor in a model of K-ras-induced pancreatic ductal adenocarcinoma.
Volume: 70
Issue: 11
Pages: 4280-6
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Publication
18589869 | J:140431
First Author: Gades NM
Year: 2008
Journal: Comp Med
Title: Spontaneous vulvar papillomas in a colony of mice used for pancreatic cancer research.
Volume: 58
Issue: 3
Pages: 271-5
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Publication
38265933 | J:346058
First Author: Lu P
Year: 2024
Journal: Cell Rep
Title: Spatiotemporal role of SETD2-H3K36me3 in murine pancreatic organogenesis.
Volume: 43
Issue: 2
Pages: 113703
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Publication
24140652 | J:346371
First Author: Lee YS
Year: 2014
Journal: Endocr J
Title: ATF3 expression is induced by low glucose in pancreatic α and β cells and regulates glucagon but not insulin gene transcription.
Volume: 61
Issue: 1
Pages: 85-90
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Publication
20622165 | J:169627
First Author: Zhao A
Year: 2010
Journal: Diabetes
Title: Gαo represses insulin secretion by reducing vesicular docking in pancreatic beta-cells.
Volume: 59
Issue: 10
Pages: 2522-9
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Publication
22814600 | J:187609
First Author: Goodyer WR
Year: 2012
Journal: Dev Cell
Title: Neonatal β cell development in mice and humans is regulated by calcineurin/NFAT.
Volume: 23
Issue: 1
Pages: 21-34
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Publication
24956127 | J:217005
First Author: Liu S
Year: 2014
Journal: Endocrinology
Title: Disruption of protein-tyrosine phosphatase 1B expression in the pancreas affects β-cell function.
Volume: 155
Issue: 9
Pages: 3329-38
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Publication
29378845 | J:262855
First Author: Zhou Z
Year: 2018
Journal: J Biol Chem
Title: Estrogen receptor α protects pancreatic β-cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress.
Volume: 293
Issue: 13
Pages: 4735-4751
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Publication
27461362 | J:235287
First Author: Bettaieb A
Year: 2016
Journal: Am J Pathol
Title: Pancreatic Protein Tyrosine Phosphatase 1B Deficiency Exacerbates Acute Pancreatitis in Mice.
Volume: 186
Issue: 8
Pages: 2043-2054
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Publication
23462798 | J:231262
First Author: Lee YS
Year: 2013
Journal: Diabetologia
Title: Hypothalamic ATF3 is involved in regulating glucose and energy metabolism in mice.
Volume: 56
Issue: 6
Pages: 1383-93
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Publication
24498408 | J:223186
First Author: Kilic G
Year: 2014
Journal: PLoS One
Title: The islet estrogen receptor-α is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes.
Volume: 9
Issue: 2
Pages: e87941
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Publication
16894357 | J:144402
First Author: Miralles F
Year: 2006
Journal: Lab Invest
Title: Conditional inactivation of the murine serum response factor in the pancreas leads to severe pancreatitis.
Volume: 86
Issue: 10
Pages: 1020-36
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Publication
25071151 | J:224344
First Author: Tersey SA
Year: 2014
Journal: Mol Cell Biol
Title: 12-lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets.
Volume: 34
Issue: 19
Pages: 3735-45
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Publication
20890745 | J:165651
First Author: Sadacca LA
Year: 2011
Journal: Diabetologia
Title: An intrinsic circadian clock of the pancreas is required for normal insulin release and glucose homeostasis in mice.
Volume: 54
Issue: 1
Pages: 120-4
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Publication
33510144 | J:300985
First Author: Liu J
Year: 2021
Journal: Nat Commun
Title: NUPR1 is a critical repressor of ferroptosis.
Volume: 12
Issue: 1
Pages: 647
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Publication
31340201 | J:353168
     
First Author: Scoville D
Year: 2019
Journal: J Endocrinol
Title: GLIS3 binds pancreatic beta cell regulatory regions alongside other islet transcription factors.
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Publication
30425062 | J:270096
First Author: Ding L
Year: 2019
Journal: Diabetes
Title: WASH Regulates Glucose Homeostasis by Facilitating Glut2 Receptor Recycling in Pancreatic β-Cells.
Volume: 68
Issue: 2
Pages: 377-386
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Publication
38007492 | J:343265
First Author: Moss ND
Year: 2023
Journal: Nat Commun
Title: Modulation of insulin secretion by RBFOX2-mediated alternative splicing.
Volume: 14
Issue: 1
Pages: 7732
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Publication
30831323 | J:294656
First Author: Kropp PA
Year: 2019
Journal: Cell Mol Gastroenterol Hepatol
Title: Regulation of the Pancreatic Exocrine Differentiation Program and Morphogenesis by Onecut 1/Hnf6.
Volume: 7
Issue: 4
Pages: 841-856
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Publication
37296979 | J:336633
 
First Author: Gaspar TB
Year: 2023
Journal: Cancers (Basel)
Title: Generation of an Obese Diabetic Mouse Model upon Conditional Atrx Disruption.
Volume: 15
Issue: 11
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Publication
25965959 | J:224613
First Author: Han S
Year: 2015
Journal: Endocrinology
Title: Pancreatic Islet APJ Deletion Reduces Islet Density and Glucose Tolerance in Mice.
Volume: 156
Issue: 7
Pages: 2451-60
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Publication
36166295 | J:331796
 
First Author: Ma N
Year: 2022
Journal: JCI Insight
Title: Interleukin-37 protects against acinar cell pyroptosis in acute pancreatitis.
Volume: 7
Issue: 21
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Publication
36654862 | J:332663
First Author: Kuo TL
Year: 2023
Journal: iScience
Title: ARID1A loss in pancreas leads to islet developmental defect and metabolic disturbance.
Volume: 26
Issue: 1
Pages: 105881
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Publication
38948355 | J:350944
 
First Author: Pollin G
Year: 2024
Journal: Front Genet
Title: Ehmt2 inactivation in pancreatic epithelial cells shapes the transcriptional landscape and inflammation response of the whole pancreas.
Volume: 15
Pages: 1412767
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Publication
28765528 | J:263577
First Author: Zhao M
Year: 2017
Journal: Sci Rep
Title: Pdx1-Cre-driven conditional gene depletion suggests PAK4 as dispensable for mouse pancreas development.
Volume: 7
Issue: 1
Pages: 7031
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Publication
34045505 | J:318055
First Author: Snyder J
Year: 2021
Journal: Sci Rep
Title: GRK2 contributes to glucose mediated calcium responses and insulin secretion in pancreatic islet cells.
Volume: 11
Issue: 1
Pages: 11129
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Publication
31831727 | J:286720
First Author: Volta F
Year: 2019
Journal: Nat Commun
Title: Glucose homeostasis is regulated by pancreatic β-cell cilia via endosomal EphA-processing.
Volume: 10
Issue: 1
Pages: 5686
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Genotype
Genotype
Symbol: Kras/Kras<+> Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S4/SvJae * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S4/SvJae * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Smad4/Smad4 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a<+> Smad4/Smad4 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S/SvEv * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Stk11/Stk11 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S6/SvEvTac * C57BL/6 * CBA * FVB/N * ICR
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S4/SvJae * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox17/Sox17 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smo/Smo Tg(Pdx1-cre)6Tuv/?
Background: involves: 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Onecut1/Onecut1 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdx1-cre/Esr1*)35.10Dam/?
Background: involves: 129S4/SvJae * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pten/Pten Tg(Pdx1-cre/Esr1*)35.10Dam/?
Background: involves: 129S4/SvJae * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Stat5a/Stat5a Stat5b/Stat5b Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S4/SvJae * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S/SvEv * C57BL/6 * C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Stard13/Stard13 Tg(Pdx1-cre)89.1Dam/?
Background: involves: C57BL/6 * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S4/SvJaeSor * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nkx2-2/Nkx2-2 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N * NTac:NIHBS * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sh2b1/Sh2b1 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bmal1/Bmal1 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129 * C57BL/6 * C57BL/6J * CBA * ICR
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdh1/Cdh1<+> Trp53/Trp53 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smad4/Smad4 Trp53/Trp53 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Alox15/Alox15 Tg(Pdx1-cre)89.1Dam/?
Background: involves: C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Atf3/Atf3 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Apc/Apc Tg(Pdx1-cre)6Tuv/?
Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Apc/Apc<+> Trp53/Trp53 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: 2610035D17Rik/2610035D17Rik Kras/Kras<+> Tg(Pdx1-cre)89.1Dam/?
Background: involves: C57BL/6JGpt * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tle3/Tle3 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Onecut1/Onecut1<+> Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdx1-cre)1Herr/?
Background: involves: 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-Bgeo/ALPP)1Lbe/? Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-Bgeo/ALPP)1Lbe/? Tg(Pdx1-cre/Esr1*)35.10Dam/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gata6/Gata6 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pdx1/Pdx1<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Onecut1/Onecut1<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1<+> Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mirc1/Mirc1 Mirc3/Mirc3 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rest/Rest Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S4/SvJae * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Neurog3/Neurog3<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ggcx/Ggcx Tg(Pdx1-cre)6Tuv/?
Background: involves: C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tff2/Tff2 Tg(Pdx1-cre)6Tuv/?
Background: involves: C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Protein
Q99LL2
Organism: Mus musculus/domesticus
Length: 122  
Fragment?: true
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Publication
11875061 | J:175106
First Author: Wang H
Year: 2002
Journal: J Biol Chem
Title: Foxa2 (HNF3beta ) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin release.
Volume: 277
Issue: 20
Pages: 17564-70
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Publication
27457971 | J:254113
 
First Author: Song MY
Year: 2016
Journal: Sci Rep
Title: Insulin secretion impairment in Sirt6 knockout pancreatic β cells is mediated by suppression of the FoxO1-Pdx1-Glut2 pathway.
Volume: 6
Pages: 30321
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Publication
10938085 | J:65512
First Author: Watada H
Year: 2000
Journal: J Biol Chem
Title: Transcriptional and translational regulation of beta-cell differentiation factor Nkx6.1.
Volume: 275
Issue: 44
Pages: 34224-30
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Publication
24645678 | J:214138
First Author: Chen Z
Year: 2014
Journal: Mol Endocrinol
Title: SH2B1 in β-cells promotes insulin expression and glucose metabolism in mice.
Volume: 28
Issue: 5
Pages: 696-705
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Publication
21614569 | J:173324
First Author: Ikeda N
Year: 2011
Journal: Diabetologia
Title: Biliverdin protects against the deterioration of glucose tolerance in db/db mice.
Volume: 54
Issue: 8
Pages: 2183-91
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Publication
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