| Type |
Details |
Score |
| Publication |
| First Author: |
Rutledge EA |
| Year: |
2017 |
| Journal: |
Development |
| Title: |
Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. |
| Volume: |
144 |
| Issue: |
17 |
| Pages: |
3177-3188 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ahuja N |
| Year: |
2022 |
| Journal: |
Dev Biol |
| Title: |
Endothelial Cyp26b1 restrains murine heart valve growth during development. |
| Volume: |
486 |
|
| Pages: |
81-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Jackson Laboratory |
| Year: |
2005 |
| Journal: |
Unpublished |
| Title: |
Information obtained from The Jackson Laboratory, Bar Harbor, ME |
|
|
|
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7356050 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2022-10-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3281327 |
| Pattern: |
Regionally restricted |
| Stage: |
TS27 |
| Assay Id: |
MGI:7356304 |
| Age: |
postnatal day 1 |
| Image: |
S7 P1 |
| Note: |
Co-expression with Ret in ganglia |
| Specimen Label: |
S7 P1 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Memic F |
| Year: |
2018 |
| Journal: |
Gastroenterology |
| Title: |
Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. |
| Volume: |
154 |
| Issue: |
3 |
| Pages: |
624-636 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Freeman TC |
| Year: |
1998 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Expression Mapping of Mouse Genes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang H |
| Year: |
2019 |
| Journal: |
Dev Cell |
| Title: |
FAT4 Fine-Tunes Kidney Development by Regulating RET Signaling. |
| Volume: |
48 |
| Issue: |
6 |
| Pages: |
780-792.e4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shanghai Model Organisms Center |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators, MGI curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gray PA |
| Year: |
2004 |
| Journal: |
Science |
| Title: |
Mouse brain organization revealed through direct genome-scale TF expression analysis. |
| Volume: |
306 |
| Issue: |
5705 |
| Pages: |
2255-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thompson CL |
| Year: |
2014 |
| Journal: |
Neuron |
| Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
| Volume: |
83 |
| Issue: |
2 |
| Pages: |
309-323 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Helmholtz Zentrum Muenchen GmbH |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2016 |
|
| Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
|
|
|
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GUDMAP Consortium |
| Year: |
2004 |
| Journal: |
www.gudmap.org |
| Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
|
| Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2014 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Magdaleno S |
| Year: |
2006 |
| Journal: |
PLoS Biol |
| Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
| Volume: |
4 |
| Issue: |
4 |
| Pages: |
e86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators |
| Year: |
2016 |
|
| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
|
| Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Amit M |
| Year: |
2017 |
| Journal: |
Oncogene |
| Title: |
Upregulation of RET induces perineurial invasion of pancreatic adenocarcinoma. |
| Volume: |
36 |
| Issue: |
23 |
| Pages: |
3232-3239 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Iwamoto T |
| Year: |
1990 |
| Journal: |
Oncogene |
| Title: |
Oncogenicity of the ret transforming gene in MMTV/ret transgenic mice. |
| Volume: |
5 |
| Issue: |
4 |
| Pages: |
535-42 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4415216 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2010-01-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716827 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:4415217 |
| Age: |
postnatal day 0 |
|
|
| Specimen Label: |
P0 ret cyto |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4415216 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2010-01-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716827 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:4415217 |
| Age: |
postnatal day 0 |
|
|
| Specimen Label: |
P0 ret nuc |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Flores-Guzmán F |
| Year: |
2020 |
| Journal: |
Cancer Lett |
| Title: |
Dormant tumor cells interact with memory CD8+ T cells in RET transgenic mouse melanoma model. |
| Volume: |
474 |
|
| Pages: |
74-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Drosten M |
| Year: |
2004 |
| Journal: |
J Natl Cancer Inst |
| Title: |
Role of MEN2A-derived RET in maintenance and proliferation of medullary thyroid carcinoma. |
| Volume: |
96 |
| Issue: |
16 |
| Pages: |
1231-9 |
|
•
•
•
•
•
|
| Allele |
| Name: |
ret proto-oncogene; targeted mutation 2.1, Hideki Enomoto |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
The RFPL defining motif (RDM) is a domain found on RFPL (Ret finger protein like) proteins. In humans, RFPL transcripts can be detected at the onset of neurogenesis in differentiating human embryonic stem cells, and in the developing human neocortex []. The RDM domain is thought to have emerged from a neofunctionalisation event. It is found N-terminal to the SPRY domain (). |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dragani TA |
| Year: |
2000 |
| Journal: |
Jpn J Cancer Res |
| Title: |
Mapping of melanoma modifier loci in RET transgenic mice. |
| Volume: |
91 |
| Issue: |
11 |
| Pages: |
1142-7 |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 3, Bruce AJ Ponder |
| Allele Type: |
Transgenic |
| Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cranston AN |
| Year: |
2003 |
| Journal: |
Cancer Res |
| Title: |
Modulation of medullary thyroid carcinoma penetrance suggests the presence of modifier genes in a RET transgenic mouse model. |
| Volume: |
63 |
| Issue: |
16 |
| Pages: |
4777-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pandey A |
| Year: |
1996 |
| Journal: |
J Biol Chem |
| Title: |
Direct association between the Ret receptor tyrosine kinase and the Src homology 2-containing adapter protein Grb7. |
| Volume: |
271 |
| Issue: |
18 |
| Pages: |
10607-10 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1073
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zeng J |
| Year: |
2009 |
| Journal: |
Cancer Res |
| Title: |
Prevention of spontaneous tumor development in a ret transgenic mouse model by ret peptide vaccination with indoleamine 2,3-dioxygenase inhibitor 1-methyl tryptophan. |
| Volume: |
69 |
| Issue: |
9 |
| Pages: |
3963-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kimpfler S |
| Year: |
2009 |
| Journal: |
J Immunol |
| Title: |
Skin melanoma development in ret transgenic mice despite the depletion of CD25+Foxp3+ regulatory T cells in lymphoid organs. |
| Volume: |
183 |
| Issue: |
10 |
| Pages: |
6330-7 |
|
•
•
•
•
•
|
| Allele |
| Name: |
ret proto-oncogene; targeted mutation 2.1, Frank Costantini |
| Allele Type: |
Targeted |
| Attribute String: |
Humanized sequence |
|
•
•
•
•
•
|
| Component |
| Name: |
Extracellular cell-membrane anchored RET cadherin 120 kDa fragment |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Allele |
| Name: |
ret proto-oncogene; targeted mutation 6.1, Hideki Enomoto |
| Allele Type: |
Targeted |
| Attribute String: |
Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guo Q |
| Year: |
2023 |
| Journal: |
Cell Rep |
| Title: |
TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation. |
| Volume: |
42 |
| Issue: |
9 |
| Pages: |
113070 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sanicola M |
| Year: |
1997 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins. |
| Volume: |
94 |
| Issue: |
12 |
| Pages: |
6238-43 |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
RET finger protein enhances MBD2- and MBD4-dependent transcriptional repression. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kato M |
| Year: |
2000 |
| Journal: |
J Invest Dermatol |
| Title: |
Ultraviolet radiation induces both full activation of ret kinase and malignant melanocytic tumor promotion in RFP-RET-transgenic mice. |
| Volume: |
115 |
| Issue: |
6 |
| Pages: |
1157-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Klein RD |
| Year: |
1997 |
| Journal: |
Nature |
| Title: |
A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor. |
| Volume: |
387 |
| Issue: |
6634 |
| Pages: |
717-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Biau S |
| Year: |
2013 |
| Journal: |
Biol Open |
| Title: |
Gastrointestinal defects of the Gas1 mutant involve dysregulated Hedgehog and Ret signaling. |
| Volume: |
2 |
| Issue: |
2 |
| Pages: |
144-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Barker SA |
| Year: |
2001 |
| Journal: |
Genomics |
| Title: |
RGSZ1 and Ret RGS: two of several splice variants from the gene RGS20. |
| Volume: |
78 |
| Issue: |
3 |
| Pages: |
223-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Garcia-Rendueles AR |
| Year: |
2021 |
| Journal: |
Oncogene |
| Title: |
RET signalling provides tumorigenic mechanism and tissue specificity for AIP-related somatotrophinomas. |
| Volume: |
40 |
| Issue: |
45 |
| Pages: |
6354-6368 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Joung H |
| Year: |
2014 |
| Journal: |
Cell Signal |
| Title: |
Ret finger protein mediates Pax7-induced ubiquitination of MyoD in skeletal muscle atrophy. |
| Volume: |
26 |
| Issue: |
10 |
| Pages: |
2240-8 |
|
•
•
•
•
•
|
| Allele |
| Name: |
ret proto-oncogene; targeted mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Allele |
| Name: |
ret proto-oncogene; targeted mutation 13.1, Jeffrey Milbrandt |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
ret proto-oncogene; targeted mutation 4.1, Hideki Enomoto |
| Allele Type: |
Targeted |
| Attribute String: |
Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bonnefont J |
| Year: |
2011 |
| Journal: |
Cell Death Differ |
| Title: |
Primate-specific RFPL1 gene controls cell-cycle progression through cyclin B1/Cdc2 degradation. |
| Volume: |
18 |
| Issue: |
2 |
| Pages: |
293-303 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Grey W |
| Year: |
2020 |
| Journal: |
Blood |
| Title: |
Activation of the receptor tyrosine kinase RET improves long-term hematopoietic stem cell outgrowth and potency. |
| Volume: |
136 |
| Issue: |
22 |
| Pages: |
2535-2547 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Moyle LA |
| Year: |
2016 |
| Journal: |
Elife |
| Title: |
Ret function in muscle stem cells points to tyrosine kinase inhibitor therapy for facioscapulohumeral muscular dystrophy. |
| Volume: |
5 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Coxon AB |
| Year: |
1998 |
| Journal: |
Oncogene |
| Title: |
RET cooperates with RB/p53 inactivation in a somatic multi-step model for murine thyroid cancer. |
| Volume: |
17 |
| Issue: |
12 |
| Pages: |
1625-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schubert L |
| Year: |
2023 |
| Journal: |
Biol Open |
| Title: |
A functional sgRNA-CRISPR screening method for generating murine RET and NTRK1 rearranged oncogenes. |
| Volume: |
12 |
| Issue: |
8 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cazes A |
| Year: |
2014 |
| Journal: |
Oncotarget |
| Title: |
Activated Alk triggers prolonged neurogenesis and Ret upregulation providing a therapeutic target in ALK-mutated neuroblastoma. |
| Volume: |
5 |
| Issue: |
9 |
| Pages: |
2688-702 |
|
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•
•
•
•
|
| Publication |
| First Author: |
Kee HJ |
| Year: |
2012 |
| Journal: |
Cell Death Differ |
| Title: |
Ret finger protein inhibits muscle differentiation by modulating serum response factor and enhancer of polycomb1. |
| Volume: |
19 |
| Issue: |
1 |
| Pages: |
121-31 |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
29 |
| Description: |
Extracellular cell-membrane anchored RET cadherin 120 kDa fragment |
| Type: |
chain |
| End: |
708 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ret/Ret |
| Background: |
involves: C57BL/6 * FVB/N * SJL |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ret/Ret |
| Background: |
involves: 129S/Sv * C57BL/6 * FVB/N |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ret/Ret |
| Background: |
involves: C57BL/6 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ret/Ret |
| Background: |
involves: C57BL/6J |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ret/Ret |
| Background: |
B6.Cg-Ret |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang J |
| Year: |
2004 |
| Journal: |
FEBS Lett |
| Title: |
PSPN/GFRalpha4 has a significantly weaker capacity than GDNF/GFRalpha1 to recruit RET to rafts, but promotes neuronal survival and neurite outgrowth. |
| Volume: |
569 |
| Issue: |
1-3 |
| Pages: |
267-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Muzyka VV |
| Year: |
2021 |
| Journal: |
Neural Dev |
| Title: |
Genetic interplay between transcription factor Pou4f1/Brn3a and neurotrophin receptor Ret in retinal ganglion cell type specification. |
| Volume: |
16 |
| Issue: |
1 |
| Pages: |
5 |
|
•
•
•
•
•
|
| Allele |
| Name: |
ret proto-oncogene; targeted mutation 2, Hideki Enomoto |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Allele |
| Name: |
ret proto-oncogene; targeted mutation 1, Patrik Ernfors |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
| Allele |
| Name: |
ret proto-oncogene; targeted mutation 5.1, Hideki Enomoto |
| Allele Type: |
Targeted |
| Attribute String: |
Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ret/Ret |
| Background: |
involves: 129S1/Sv * C57BL/6J * FVB/N |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Regulatory Region |
| Type: |
enhancer |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nguyen Ho-Bouldoires TH |
| Year: |
2022 |
| Journal: |
Commun Biol |
| Title: |
Ret kinase-mediated mechanical induction of colon stem cells by tumor growth pressure stimulates cancer progression in vivo. |
| Volume: |
5 |
| Issue: |
1 |
| Pages: |
137 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cavel O |
| Year: |
2012 |
| Journal: |
Cancer Res |
| Title: |
Endoneurial macrophages induce perineural invasion of pancreatic cancer cells by secretion of GDNF and activation of RET tyrosine kinase receptor. |
| Volume: |
72 |
| Issue: |
22 |
| Pages: |
5733-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shimono Y |
| Year: |
2000 |
| Journal: |
J Biol Chem |
| Title: |
RET finger protein is a transcriptional repressor and interacts with enhancer of polycomb that has dual transcriptional functions. |
| Volume: |
275 |
| Issue: |
50 |
| Pages: |
39411-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Acton DS |
| Year: |
2000 |
| Journal: |
Oncogene |
| Title: |
Multiple endocrine neoplasia type 2B mutation in human RET oncogene induces medullary thyroid carcinoma in transgenic mice. |
| Volume: |
19 |
| Issue: |
27 |
| Pages: |
3121-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawai K |
| Year: |
2003 |
| Journal: |
Cancer Sci |
| Title: |
Establishment and characterization of mouse mammary carcinoma cell lines expressing RET with a multiple endocrine neoplasia 2A mutation. |
| Volume: |
94 |
| Issue: |
11 |
| Pages: |
992-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
He Z |
| Year: |
2007 |
| Journal: |
Biol Reprod |
| Title: |
Gfra1 silencing in mouse spermatogonial stem cells results in their differentiation via the inactivation of RET tyrosine kinase. |
| Volume: |
77 |
| Issue: |
4 |
| Pages: |
723-33 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ret/Ret |
| Background: |
involves: 129/Sv * C57BL/6 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen S |
| Year: |
1996 |
| Journal: |
J Biol Chem |
| Title: |
Ret 4, a positive acting rhodopsin regulatory element identified using a bovine retina in vitro transcription system. |
| Volume: |
271 |
| Issue: |
45 |
| Pages: |
28549-57 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cao T |
| Year: |
1996 |
| Journal: |
Dev Genet |
| Title: |
Mouse ret finger protein (rfp) proto-oncogene is expressed at specific stages of mouse spermatogenesis. |
| Volume: |
19 |
| Issue: |
4 |
| Pages: |
309-20 |
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•
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