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Search results 22601 to 22700 out of 2418182 for a

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Type Details Score
Allele
Eloa<tm1Aso> | MGI:3701319
Name: elongin A; targeted mutation 1, T Aso
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
10508511 | J:57881
First Author: Persons DA
Year: 1999
Journal: Nat Genet
Title: Fv2 encodes a truncated form of the Stk receptor tyrosine kinase.
Volume: 23
Issue: 2
Pages: 159-65
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Publication
31828288 | J:293410
First Author: Kannan A
Year: 2020
Journal: Brain
Title: ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy.
Volume: 143
Issue: 1
Pages: 69-93
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Publication
18852040 | J:143291
First Author: Asami DK
Year: 2008
Journal: Exp Gerontol
Title: Effect of aging, caloric restriction, and uncoupling protein 3 (UCP3) on mitochondrial proton leak in mice.
Volume: 43
Issue: 12
Pages: 1069-76
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Publication
7984047 | J:20051
First Author: Soosaar A
Year: 1994
Journal: Brain Res Mol Brain Res
Title: Expression of basic-helix-loop-helix transcription factor ME2 during brain development and in the regions of neuronal plasticity in the adult brain.
Volume: 25
Issue: 1-2
Pages: 176-80
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Publication
31810491 | J:290810
First Author: Montoya A
Year: 2019
Journal: J Neuroinflammation
Title: Dopamine receptor D3 signalling in astrocytes promotes neuroinflammation.
Volume: 16
Issue: 1
Pages: 258
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Publication
35619220 | J:326605
First Author: Nacarino-Palma A
Year: 2022
Journal: Aging (Albany NY)
Title: Aryl hydrocarbon receptor blocks aging-induced senescence in the liver and fibroblast cells.
Volume: 14
Issue: 10
Pages: 4281-4304
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Publication
23998933 | J:211369
First Author: Kim Y
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Generation and characterization of a conditional deletion allele for Lmna in mice.
Volume: 440
Issue: 1
Pages: 8-13
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Publication
12837776 | -
First Author: Teplyakov A
Year: 2003
Journal: J Bacteriol
Title: Crystal structure of the YchF protein reveals binding sites for GTP and nucleic acid.
Volume: 185
Issue: 14
Pages: 4031-7
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Publication
29311329 | J:260599
First Author: Bélanger C
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Dysregulation of cotranscriptional alternative splicing underlies CHARGE syndrome.
Volume: 115
Issue: 4
Pages: E620-E629
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Publication
22456507 | J:197801
First Author: Orsi A
Year: 2012
Journal: Mol Biol Cell
Title: Dynamic and transient interactions of Atg9 with autophagosomes, but not membrane integration, are required for autophagy.
Volume: 23
Issue: 10
Pages: 1860-73
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Publication
20053268 | J:158428
 
First Author: Arora A
Year: 2010
Journal: BMC Dev Biol
Title: Prediction of microRNAs affecting mRNA expression during retinal development.
Volume: 10
Pages: 1
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Publication
30822685 | J:347218
 
First Author: Zhang SM
Year: 2019
Journal: Atherosclerosis
Title: A disintegrin and metalloprotease 22 accelerates neointima formation by activating ERK signaling.
Volume: 283
Pages: 92-99
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Publication
28948621 | J:354410
First Author: Hagemann A
Year: 2017
Journal: FEBS Lett
Title: Exploring the putative self-binding property of the human farnesyltransferase alpha-subunit.
Volume: 591
Issue: 21
Pages: 3637-3648
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Publication
22982048 | J:229367
First Author: Höhn A
Year: 2012
Journal: Free Radic Biol Med
Title: Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts.
Volume: 53
Issue: 9
Pages: 1760-9
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Publication
33441438 | J:306133
First Author: Bianchi A
Year: 2021
Journal: J Immunol
Title: Moderate Exercise Inhibits Age-Related Inflammation, Liver Steatosis, Senescence, and Tumorigenesis.
Volume: 206
Issue: 4
Pages: 904-916
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Publication
25348714 | J:224312
First Author: Qiu Z
Year: 2015
Journal: Mol Cell Biol
Title: Functional interactions between NURF and Ctcf regulate gene expression.
Volume: 35
Issue: 1
Pages: 224-37
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Publication
10648716 | J:59968
First Author: Mallamaci A
Year: 2000
Journal: J Neurosci
Title: The lack of Emx2 causes impairment of Reelin signaling and defects of neuronal migration in the developing cerebral cortex.
Volume: 20
Issue: 3
Pages: 1109-18
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Publication
12079357 | J:77610
First Author: Whitby FG
Year: 2002
Journal: J Mol Biol
Title: Crystal structure of a biliverdin IXalpha reductase enzyme-cofactor complex.
Volume: 319
Issue: 5
Pages: 1199-210
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Publication
57640 | J:31041
First Author: Westermark P
Year: 1976
Journal: Scand J Immunol
Title: Coexistence of protein AA and immunoglobulin light-chain fragments in amyloid fibrils.
Volume: 5
Issue: 1-2
Pages: 31-6
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Publication
35887068 | J:326841
 
First Author: Scagliola A
Year: 2022
Journal: Int J Mol Sci
Title: Inhibition of eIF6 Activity Reduces Hepatocellular Carcinoma Growth: An In Vivo and In Vitro Study.
Volume: 23
Issue: 14
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Publication
10611283 | J:59088
First Author: Zhu H
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Identification of a cytochrome b-type NAD(P)H oxidoreductase ubiquitously expressed in human cells.
Volume: 96
Issue: 26
Pages: 14742-7
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Publication
28752643 | J:247935
First Author: Sophocleous A
Year: 2017
Journal: Aging Cell
Title: Combined deficiency of the Cnr1 and Cnr2 receptors protects against age-related bone loss by osteoclast inhibition.
Volume: 16
Issue: 5
Pages: 1051-1061
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Publication
19457069 | J:152822
First Author: Chan A
Year: 2009
Journal: J Neurochem
Title: Dietary deficiency increases presenilin expression, gamma-secretase activity, and Abeta levels: potentiation by ApoE genotype and alleviation by S-adenosyl methionine.
Volume: 110
Issue: 3
Pages: 831-6
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Publication
21678127 | J:197592
First Author: Kyono A
Year: 2012
Journal: J Bone Miner Metab
Title: FGF and ERK signaling coordinately regulate mineralization-related genes and play essential roles in osteocyte differentiation.
Volume: 30
Issue: 1
Pages: 19-30
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Publication
24913981 | J:307280
First Author: Allam A
Year: 2014
Journal: J Immunol
Title: Dual function of CD70 in viral infection: modulator of early cytokine responses and activator of adaptive responses.
Volume: 193
Issue: 2
Pages: 871-8
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Publication
11983912 | J:76332
First Author: Weber BH
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Inactivation of the murine X-linked juvenile retinoschisis gene, Rs1h, suggests a role of retinoschisin in retinal cell layer organization and synaptic structure.
Volume: 99
Issue: 9
Pages: 6222-7
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Publication
31364453 | J:285433
First Author: Peter AK
Year: 2019
Journal: J Am Heart Assoc
Title: Expression of Normally Repressed Myosin Heavy Chain 7b in the Mammalian Heart Induces Dilated Cardiomyopathy.
Volume: 8
Issue: 15
Pages: e013318
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Publication
16049178 | J:100025
First Author: Niewmierzycka A
Year: 2005
Journal: J Neurosci
Title: Integrin-linked kinase deletion from mouse cortex results in cortical lamination defects resembling cobblestone lissencephaly.
Volume: 25
Issue: 30
Pages: 7022-31
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Publication
6166005 | J:32658
First Author: Parnes JR
Year: 1981
Journal: Proc Natl Acad Sci U S A
Title: Mouse beta 2-microglobulin cDNA clones: a screening procedure for cDNA clones corresponding to rare mRNAs.
Volume: 78
Issue: 4
Pages: 2253-7
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Publication
26116663 | J:224146
First Author: O'Shaughnessy-Kirwan A
Year: 2015
Journal: Development
Title: Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification.
Volume: 142
Issue: 15
Pages: 2586-97
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SO Term
SO:0001152 | beta_turn_type_six_a_one
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SO Term
SO:0001153 | beta_turn_type_six_a_two
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Publication
9524576 | J:46683
First Author: Matin A
Year: 1998
Journal: APMIS
Title: Testicular teratocarcinogenesis in mice--a review.
Volume: 106
Issue: 1
Pages: 174-82
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Publication
21884699 | J:178378
First Author: Mazarati A
Year: 2011
Journal: Exp Neurol
Title: High-mobility group box-1 impairs memory in mice through both toll-like receptor 4 and Receptor for Advanced Glycation End Products.
Volume: 232
Issue: 2
Pages: 143-8
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Publication
20139986 | J:158628
First Author: Stadinski BD
Year: 2010
Journal: Nat Immunol
Title: Chromogranin A is an autoantigen in type 1 diabetes.
Volume: 11
Issue: 3
Pages: 225-31
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Publication
24391210 | J:207299
First Author: Fujita Y
Year: 2014
Journal: J Immunol
Title: Deficient leptin signaling ameliorates systemic lupus erythematosus lesions in MRL/Mp-Fas lpr mice.
Volume: 192
Issue: 3
Pages: 979-84
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Publication
38265933 | J:346058
First Author: Lu P
Year: 2024
Journal: Cell Rep
Title: Spatiotemporal role of SETD2-H3K36me3 in murine pancreatic organogenesis.
Volume: 43
Issue: 2
Pages: 113703
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Publication
7854413 | -
First Author: Volbeda A
Year: 1995
Journal: Nature
Title: Crystal structure of the nickel-iron hydrogenase from Desulfovibrio gigas.
Volume: 373
Issue: 6515
Pages: 580-7
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Publication
23149942 | J:194102
First Author: Huh JY
Year: 2013
Journal: Mol Cell Biol
Title: A novel function of adipocytes in lipid antigen presentation to iNKT cells.
Volume: 33
Issue: 2
Pages: 328-39
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Publication
15181014 | J:121205
First Author: Shi H
Year: 2004
Journal: J Biol Chem
Title: Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling.
Volume: 279
Issue: 33
Pages: 34733-40
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Publication
24585709 | J:233235
First Author: Fajardo RJ
Year: 2014
Journal: J Bone Miner Res
Title: A review of rodent models of type 2 diabetic skeletal fragility.
Volume: 29
Issue: 5
Pages: 1025-40
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Publication
23478020 | J:270364
First Author: Kaushansky A
Year: 2013
Journal: Cell Rep
Title: Suppression of host p53 is critical for Plasmodium liver-stage infection.
Volume: 3
Issue: 3
Pages: 630-7
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Publication
29282321 | J:260593
First Author: Carrette LLG
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: A mixed modality approach towards Xi reactivation for Rett syndrome and other X-linked disorders.
Volume: 115
Issue: 4
Pages: E668-E675
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Publication
36445254 | J:333622
First Author: Ko A
Year: 2023
Journal: Cancer Discov
Title: LZTR1 Mutation Mediates Oncogenesis through Stabilization of EGFR and AXL.
Volume: 13
Issue: 3
Pages: 702-723
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Publication
11438547 | J:120510
First Author: Mukhopadhyay A
Year: 2001
Journal: J Biol Chem
Title: Genetic deletion of the tumor necrosis factor receptor p60 or p80 abrogates ligand-mediated activation of nuclear factor-kappa B and of mitogen-activated protein kinases in macrophages.
Volume: 276
Issue: 34
Pages: 31906-12
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Publication
10023815 | J:53687
First Author: Rau A
Year: 1999
Journal: J Comp Neurol
Title: Tectorin mRNA expression is spatially and temporally restricted during mouse inner ear development.
Volume: 405
Issue: 2
Pages: 271-80
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Publication
18555800 | J:137370
First Author: Seebahn A
Year: 2008
Journal: FEBS Lett
Title: RanBPM is expressed in synaptic layers of the mammalian retina and binds to metabotropic glutamate receptors.
Volume: 582
Issue: 16
Pages: 2453-7
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Publication
19666503 | J:151965
First Author: Liem KF Jr
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling.
Volume: 106
Issue: 32
Pages: 13377-82
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Publication
31895747 | J:295180
First Author: Terauchi A
Year: 2020
Journal: Neuroreport
Title: Neuronal fibroblast growth factor 22 signaling during development, but not in adults, is involved in anhedonia.
Volume: 31
Issue: 2
Pages: 125-130
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Publication
16766661 | J:111034
First Author: Risueño RM
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: A conformational change senses the strength of T cell receptor-ligand interaction during thymic selection.
Volume: 103
Issue: 25
Pages: 9625-30
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Publication
22308431 | J:182612
First Author: Zhou HF
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Antibody directs properdin-dependent activation of the complement alternative pathway in a mouse model of abdominal aortic aneurysm.
Volume: 109
Issue: 7
Pages: E415-22
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Publication
19720760 | J:154191
First Author: Fortier A
Year: 2009
Journal: Infect Immun
Title: Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4.
Volume: 77
Issue: 11
Pages: 4794-805
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Protein Domain
IPR023536 | CoA_disulphide_reductase_staph
Type: Family
Description: Coenzyme A disulphide reductase () has been characterised in Staphylococcus aureus, Pyrococcus horikoshii, and Borrelia burgdorferi (Lyme disease spirochete), and inferred in several other species on the basis of high levels of CoA and an absence of glutathione as a protective thiol. Coenzyme A disulphide reductase specifically catalyses the NAD(P)H-dependent reduction of coenzyme A disulphide using FAD and NAD(P)H [, , ]. In some species the enzymes show a distinct preference for NADH or NADPH, while others can use either substrate equally well. The reduction of disulphides occurs by a thiol-disulphide exchange reaction, but involves only a single catalytic cysteine residue that forms a stable mixed disulphide with CoA during catalysis. This enzyme contains 2 FAD binding domains and a single NAD(P)H binding domain [].This entryrepresents a distinct subgroup of coenzyme A disulphide reductases, so far found only in Staphylococcus species. These enzymes are specific for NADPH [].
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Publication
28652369 | J:244961
First Author: Gocheva V
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival.
Volume: 114
Issue: 28
Pages: E5625-E5634
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Publication
30218791 | J:267714
 
First Author: Karvande A
Year: 2018
Journal: Bone
Title: Glucose dependent miR-451a expression contributes to parathyroid hormone mediated osteoblast differentiation.
Volume: 117
Pages: 98-115
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Publication
31125592 | J:289308
First Author: Saku A
Year: 2019
Journal: J Allergy Clin Immunol
Title: Fucosyltransferase 2 induces lung epithelial fucosylation and exacerbates house dust mite-induced airway inflammation.
Volume: 144
Issue: 3
Pages: 698-709.e9
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Publication
20080688 | J:156532
First Author: Hung KE
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment.
Volume: 107
Issue: 4
Pages: 1565-70
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Protein Domain
IPR012274 | Alpha-crystallin_A
Type: Family
Description: The crystallins are water-soluble structural proteins that occur in high concentration in the cytoplasm of eye lens fibre cells. Four major groups of crystallin have been distinguished on the basis of size, charge and immunological properties: alpha-, beta- and gamma-crystallins occur in all vertebrate classes (though gamma-crystallins are low or absent in avian lenses); and delta-crystallin is found exclusively in reptiles and birds [, ].Alpha-crystallin occurs as large aggregates, comprising two types of related subunits or chains (A and B) that are highly similar to the small (15-30kDa) heat shock proteins (HSPs), particularly in their C-terminal halves. The relationship between these families is one of classic gene duplication and divergence, from the small HSP family, allowing adaptation to novel functions. Divergence probably occurred prior to evolution of the eye lens, alpha-crystallin being found in small amounts in tissues outside the lens [].Alpha-crystallin has chaperone-like properties including the ability to prevent the precipitation of denatured proteins and to increase cellular tolerance to stress []. It has been suggested that these functions are important for the maintenance of lens transparency and the prevention of cataracts. This is supported by the observation that alpha-crystallin mutations show an association with cataract formation.This group represents the A subunit (or chain) of alpha-crystallin.
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Publication
15668387 | J:96103
First Author: Champion HC
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Phosphodiesterase-5A dysregulation in penile erectile tissue is a mechanism of priapism.
Volume: 102
Issue: 5
Pages: 1661-6
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Publication
15677329 | J:96506
First Author: Letts VA
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: A targeted mutation in Cacng4 exacerbates spike-wave seizures in stargazer (Cacng2) mice.
Volume: 102
Issue: 6
Pages: 2123-8
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Publication
18245377 | J:131932
First Author: Klezovitch O
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: A causal role for ERG in neoplastic transformation of prostate epithelium.
Volume: 105
Issue: 6
Pages: 2105-10
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Publication
18498746 | J:137061
First Author: Hübner A
Year: 2008
Journal: Mol Cell
Title: Multisite phosphorylation regulates Bim stability and apoptotic activity.
Volume: 30
Issue: 4
Pages: 415-25
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Publication
10973493 | J:64483
First Author: Lahvis GP
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice.
Volume: 97
Issue: 19
Pages: 10442-7
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Publication
23836658 | J:198789
First Author: Shin JH
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Modulation of natural killer cell antitumor activity by the aryl hydrocarbon receptor.
Volume: 110
Issue: 30
Pages: 12391-6
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Publication
18227284 | J:196096
First Author: Millon-Frémillon A
Year: 2008
Journal: J Cell Biol
Title: Cell adaptive response to extracellular matrix density is controlled by ICAP-1-dependent beta1-integrin affinity.
Volume: 180
Issue: 2
Pages: 427-41
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Publication
17962413 | J:127160
First Author: Pimanda JE
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development.
Volume: 104
Issue: 45
Pages: 17692-7
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Publication
34983562 | J:318729
First Author: Bedolla A
Year: 2022
Journal: J Neuroinflammation
Title: Diphtheria toxin induced but not CSF1R inhibitor mediated microglia ablation model leads to the loss of CSF/ventricular spaces in vivo that is independent of cytokine upregulation.
Volume: 19
Issue: 1
Pages: 3
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Publication
11461925 | J:71660
First Author: Miyazaki T
Year: 2001
Journal: J Biol Chem
Title: Fatal propionic acidemia in mice lacking propionyl-CoA carboxylase and its rescue by postnatal, liver-specific supplementation via a transgene.
Volume: 276
Issue: 38
Pages: 35995-9
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Publication
22550175 | J:184789
First Author: Lee MJ
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Hedgehog pathway inhibitor saridegib (IPI-926) increases lifespan in a mouse medulloblastoma model.
Volume: 109
Issue: 20
Pages: 7859-64
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Protein Coding Gene
MGI:1917135 | Aunip
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
22152679 | J:191534
First Author: Bloch-Zupan A
Year: 2011
Journal: Am J Hum Genet
Title: Homozygosity mapping and candidate prioritization identify mutations, missed by whole-exome sequencing, in SMOC2, causing major dental developmental defects.
Volume: 89
Issue: 6
Pages: 773-81
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Protein
F6V4U2
Organism: Mus musculus/domesticus
Length: 216  
Fragment?: true
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Protein
F6XLJ8
Organism: Mus musculus/domesticus
Length: 163  
Fragment?: true
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Publication
22157680 | J:180794
First Author: Schneider A
Year: 2011
Journal: Nat Med
Title: Successful prenatal mannose treatment for congenital disorder of glycosylation-Ia in mice.
Volume: 18
Issue: 1
Pages: 71-3
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Publication
37371067 | J:351122
 
First Author: Lee-Gosselin A
Year: 2023
Journal: Cells
Title: TREM2-Deficient Microglia Attenuate Tau Spreading In Vivo.
Volume: 12
Issue: 12
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Publication
27466285 | J:235134
First Author: Banerjee A
Year: 2016
Journal: Cancer Res
Title: Lack of p53 Augments Antitumor Functions in Cytolytic T Cells.
Volume: 76
Issue: 18
Pages: 5229-5240
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Publication
20498066 | J:161290
First Author: Chizhikov VV
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Lmx1a regulates fates and location of cells originating from the cerebellar rhombic lip and telencephalic cortical hem.
Volume: 107
Issue: 23
Pages: 10725-30
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Publication
10430869 | J:230398
First Author: Traub LM
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly.
Volume: 96
Issue: 16
Pages: 8907-12
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Publication
33195211 | J:313588
 
First Author: Taghizadeh S
Year: 2020
Journal: Front Cell Dev Biol
Title: Fgf10 Signaling-Based Evidence for the Existence of an Embryonic Stage Distinct From the Pseudoglandular Stage During Mouse Lung Development.
Volume: 8
Pages: 576604
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Publication
22865884 | J:315490
First Author: Arriola DJ
Year: 2012
Journal: J Biol Chem
Title: FOXO1 transcription factor inhibits luteinizing hormone β gene expression in pituitary gonadotrope cells.
Volume: 287
Issue: 40
Pages: 33424-35
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Publication
32664967 | J:306208
First Author: Wu J
Year: 2020
Journal: BMC Biol
Title: FAM20B-catalyzed glycosaminoglycans control murine tooth number by restricting FGFR2b signaling.
Volume: 18
Issue: 1
Pages: 87
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Publication
22386268 | J:187337
First Author: Moseman EA
Year: 2012
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