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Search results 2301 to 2400 out of 2731 for Akt1

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Type Details Score
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication  
First Author: Meuser M
Year: 2022
Journal: Development
Title: FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development.
Volume: 149
Issue: 1
Publication  
First Author: Koutelou E
Year: 2019
Journal: Development
Title: USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta.
Volume: 146
Issue: 4
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
Publication      
First Author: Freeman TC
Year: 1998
Journal: MGI Direct Data Submission
Title: Expression Mapping of Mouse Genes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Alliouachene S
Year: 2008
Journal: J Clin Invest
Title: Constitutively active Akt1 expression in mouse pancreas requires S6 kinase 1 for insulinoma formation.
Volume: 118
Issue: 11
Pages: 3629-38
Allele    
Name: AKT1 substrate 1; wild type
HT Experiment
Series Id: GSE28664
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
HT Experiment
Series Id: GSE30671
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Jo J
Year: 2011
Journal: Nat Neurosci
Title: Aβ(1-42) inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3β.
Volume: 14
Issue: 5
Pages: 545-7
Publication
First Author: Priolo C
Year: 2014
Journal: Cancer Res
Title: AKT1 and MYC induce distinctive metabolic fingerprints in human prostate cancer.
Volume: 74
Issue: 24
Pages: 7198-204
Interaction Experiment
Description: Akt1 sequentially phosphorylates p27kip1 within a conserved but non-canonical region.
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Chern JJ
Year: 2002
Journal: Development
Title: Lobe mediates Notch signaling to control domain-specific growth in the Drosophila eye disc.
Volume: 129
Issue: 17
Pages: 4005-13
Publication
First Author: Völkers M
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Pathological hypertrophy amelioration by PRAS40-mediated inhibition of mTORC1.
Volume: 110
Issue: 31
Pages: 12661-6
Publication
First Author: Völkers M
Year: 2014
Journal: EMBO Mol Med
Title: PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity.
Volume: 6
Issue: 1
Pages: 57-65
GXD Expression      
Probe: MGI:7529179
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7529190
Age: embryonic day 15.5
Specimen Label: E15.5 WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7529179
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7529190
Age: embryonic day 15.5
Specimen Label: E15.5 WT
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7529179
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7529190
Age: embryonic day 15.5
Specimen Label: E15.5 K465E
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7529179
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7529190
Age: embryonic day 15.5
Specimen Label: E15.5 K465E
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7529179
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7529190
Age: postnatal adult
Specimen Label: ADULT WT
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7529179
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7529190
Age: postnatal adult
Specimen Label: ADULT WT
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7529179
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7529190
Age: postnatal adult
Specimen Label: ADULT K465E
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7529179
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7529190
Age: postnatal adult
Specimen Label: ADULT K465E
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:7529180
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7529191
Age: embryonic day 15.5
Specimen Label: E15.5 WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7529180
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7529191
Age: embryonic day 15.5
Specimen Label: E15.5 WT
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7529180
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7529191
Age: embryonic day 15.5
Specimen Label: E15.5 K465E
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7529180
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7529191
Age: embryonic day 15.5
Specimen Label: E15.5 K465E
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7529180
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7529191
Age: postnatal adult
Specimen Label: ADULT WT
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7529180
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7529191
Age: postnatal adult
Specimen Label: ADULT WT
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7529180
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7529191
Age: postnatal adult
Specimen Label: ADULT K465E
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7529180
Assay Type: Western blot
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7529191
Age: postnatal adult
Specimen Label: ADULT K465E
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:6167237
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189760
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Akt1s1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6167237
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6189760
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Akt1s1
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6167237
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6189760
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Akt1s1
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6167237
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6189760
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Akt1s1
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:6167237
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6189760
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Akt1s1
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:6167237
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6189760
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Akt1s1
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:6167237
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6189760
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Akt1s1
Detected: false
Specimen Num: 7
Publication
First Author: Barthel A
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Protein kinase C modulates the insulin-stimulated increase in Akt1 and Akt3 activity in 3T3-L1 adipocytes.
Volume: 243
Issue: 2
Pages: 509-13
Publication
First Author: Limesand KH
Year: 2006
Journal: Mol Cell Biol
Title: MDM2 is required for suppression of apoptosis by activated Akt1 in salivary acinar cells.
Volume: 26
Issue: 23
Pages: 8840-56
Publication
First Author: Chen T
Year: 2024
Journal: Nat Commun
Title: AKT1 phosphorylation of cytoplasmic ME2 induces a metabolic switch to glycolysis for tumorigenesis.
Volume: 15
Issue: 1
Pages: 686
Allele  
Name: AKT1 substrate 1; gene trap CSI571, BayGenomics
Allele Type: Gene trapped
Allele
Name: AKT1 substrate 1; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Publication
First Author: Staal SP
Year: 1987
Journal: Proc Natl Acad Sci U S A
Title: Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma.
Volume: 84
Issue: 14
Pages: 5034-7
Publication
First Author: Durham KK
Year: 2018
Journal: Biochem J
Title: High-density lipoprotein protects cardiomyocytes against necrosis induced by oxygen and glucose deprivation through SR-B1, PI3K, and AKT1 and 2.
Volume: 475
Issue: 7
Pages: 1253-1265
Publication
First Author: Sharma N
Year: 2016
Journal: Development
Title: Tpbpa-Cre-mediated deletion of TFAP2C leads to deregulation of Cdkn1a, Akt1 and the ERK pathway, causing placental growth arrest.
Volume: 143
Issue: 5
Pages: 787-98
Publication
First Author: Tang Y
Year: 2015
Journal: Exp Hematol
Title: Coexpression of hyperactivated AKT1 with additional genes activated in leukemia drives hematopoietic progenitor cells to cell cycle block and apoptosis.
Volume: 43
Issue: 7
Pages: 554-64
DO Term
Interaction Experiment
Description: Akt1 mediates the posterior Hoxc gene expression through epigenetic modifications in mouse embryonic fibroblasts.
Allele  
Name: AKT1 substrate 1; gene trap D080H12, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: AKT1 substrate 1; gene trap D084C06, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: AKT1 substrate 1; gene trap D160A07, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: AKT1 substrate 1; gene trap OST169856, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: AKT1 substrate 1; gene trap OST197518, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: AKT1 substrate 1; gene trap OST258537, Lexicon Genetics
Allele Type: Gene trapped