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Search results 2301 to 2400 out of 4306 for C3

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Type Details Score
Publication
15664190 | J:95513
First Author: Saci A
Year: 2005
Journal: Mol Cell
Title: RhoA GTPase regulates B cell receptor signaling.
Volume: 17
Issue: 2
Pages: 205-14
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Publication
17298982 | J:120754
First Author: Weston CA
Year: 2007
Journal: J Cell Sci
Title: Agrin and laminin induce acetylcholine receptor clustering by convergent, Rho GTPase-dependent signaling pathways.
Volume: 120
Issue: Pt 5
Pages: 868-75
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Publication
29497040 | J:282133
First Author: Lv Z
Year: 2018
Journal: Cell Death Dis
Title: Podocyte-specific Rac1 deficiency ameliorates podocyte damage and proteinuria in STZ-induced diabetic nephropathy in mice.
Volume: 9
Issue: 3
Pages: 342
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Publication
2649282 | J:281100
First Author: Yoshioka H
Year: 1989
Journal: Clin Exp Immunol
Title: Autoimmune abnormalities in a murine model of accelerated senescence.
Volume: 75
Issue: 1
Pages: 129-35
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Publication
38361607 | J:351642
First Author: Bose K
Year: 2024
Journal: iScience
Title: Sleep fragmentation induces heart failure in a hypertrophic cardiomyopathy mouse model by altering redox metabolism.
Volume: 27
Issue: 3
Pages: 109075
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Protein Coding Gene
MGI:1330346 | Sprr2e
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2684996 | Ccdc62
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
16002709 | J:100702
First Author: Chen Y
Year: 2005
Journal: J Immunol
Title: Several genes contribute to the production of autoreactive B and T cells in the murine lupus susceptibility locus Sle1c.
Volume: 175
Issue: 2
Pages: 1080-9
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Protein
A0A0G2JGY4
Organism: Mus musculus/domesticus
Length: 153  
Fragment?: true
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Publication
1551442 | -
First Author: Koonin EV
Year: 1992
Journal: FEBS Lett
Title: An insect picornavirus may have genome organization similar to that of caliciviruses.
Volume: 297
Issue: 1-2
Pages: 81-6
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Publication
8642693 | -
First Author: Liu B
Year: 1996
Journal: J Virol
Title: Polyprotein processing in Southampton virus: identification of 3C-like protease cleavage sites by in vitro mutagenesis.
Volume: 70
Issue: 4
Pages: 2605-10
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Publication
1840711 | -
First Author: Meyers G
Year: 1991
Journal: Virology
Title: Rabbit hemorrhagic disease virus--molecular cloning and nucleotide sequencing of a calicivirus genome.
Volume: 184
Issue: 2
Pages: 664-76
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Publication
22832194 | -
First Author: Hadders MA
Year: 2012
Journal: Cell Rep
Title: Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.
Volume: 1
Issue: 3
Pages: 200-7
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Protein Domain
IPR044067 | PCV_3C_PRO
Type: Domain
Description: Viruses in the order Picornavirales infect different vertebrate, invertebrate, and plant hosts and are responsible for a variety of human, animal, and plant diseases. These viruses have a single-stranded, positive sense RNA genome that generally translates a large precursor polyprotein which is proteolytically cleaved after translation to generate mature functional viral proteins. This process is usually mediated by (more than one) proteases, and a 3C (for the family Picornaviridae) or 3C-like (3CL) protease (for other families) plays a central role in the cleavage of the viral precursor polyprotein. In addition to this key role, 3C/3C-like protease is able to cleave a number of host proteins to remodel the cellular environment for virus reproduction [, , , , , ]. The Picornavirales 3C/3C-like protease domain forms the MEROPS peptidase family C3 (picornain family) of clan PA.The 3C/3CL protease domain adopts a chymotrypsin-like fold with a cysteine nucleophile in place of a commonly found serine which suggests that the cysteine and serine perform an analogous catalytic function. The catalytic triad is made of a histidine, an aspartate/glutamate and the conserved cysteine in this sequential order. The 3C/3CL protease domain folds into two antiparallel beta barrels that are linked by a loop with a short α-helix in its middle, and flanked by two other α-helices at the N- and C-terminal. The two barrels are topologically equivalent and are formed by six antiparallel beta strands with the first four organised into a Greek key motif. The active-site residues are located in the cleft between the two barrels with the nucleophilic Cys from the C-terminal barrel and the general acid base His-Glu/Asp from the N-terminal barrel [, , ].
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Protein
E1APH6
Organism: Mus musculus/domesticus
Length: 312  
Fragment?: true
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Protein
Q207D2
Organism: Mus musculus/domesticus
Length: 299  
Fragment?: true
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Protein
B5APU1
Organism: Mus musculus/domesticus
Length: 293  
Fragment?: true
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Publication
26816051 | J:250104
First Author: Flodby P
Year: 2016
Journal: Am J Respir Cell Mol Biol
Title: The 78-kD Glucose-Regulated Protein Regulates Endoplasmic Reticulum Homeostasis and Distal Epithelial Cell Survival during Lung Development.
Volume: 55
Issue: 1
Pages: 135-49
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Publication
7791626 | -
 
First Author: Neet KE
Year: 1995
Journal: Methods Enzymol
Title: Cooperativity in enzyme function: equilibrium and kinetic aspects.
Volume: 249
Pages: 519-67
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Publication
10600394 | -
First Author: Cunin R
Year: 1999
Journal: J Mol Biol
Title: Intramolecular signal transmission in enterobacterial aspartate transcarbamylases II. Engineering co-operativity and allosteric regulation in the aspartate transcarbamylase of Erwinia herbicola.
Volume: 294
Issue: 5
Pages: 1401-11
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Publication
10651286 | -
First Author: Jin L
Year: 1999
Journal: Proteins
Title: Insights into the mechanisms of catalysis and heterotropic regulation of Escherichia coli aspartate transcarbamoylase based upon a structure of the enzyme complexed with the bisubstrate analogue N-phosphonacetyl-L-aspartate at 2.1 A.
Volume: 37
Issue: 4
Pages: 729-42
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Publication
11323717 | -
First Author: Macol CP
Year: 2001
Journal: Nat Struct Biol
Title: Direct structural evidence for a concerted allosteric transition in Escherichia coli aspartate transcarbamoylase.
Volume: 8
Issue: 5
Pages: 423-6
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Publication
29662056 | J:261928
First Author: Lee JY
Year: 2018
Journal: Nat Commun
Title: Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease.
Volume: 9
Issue: 1
Pages: 1479
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Publication
29985482 | J:267431
First Author: Kotelevets L
Year: 2018
Journal: Oncogene
Title: The Rac1 splice form Rac1b favors mouse colonic mucosa regeneration and contributes to intestinal cancer progression.
Volume: 37
Issue: 46
Pages: 6054-6068
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Publication
11447257 | J:79298
First Author: Polic B
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: How alpha beta T cells deal with induced TCR alpha ablation.
Volume: 98
Issue: 15
Pages: 8744-9
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Publication
15888345 | J:100623
First Author: Shen Q
Year: 2005
Journal: Mutat Res
Title: Transgenic mouse models for the prevention of breast cancer.
Volume: 576
Issue: 1-2
Pages: 93-110
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Publication
21880986 | J:179327
First Author: Qui HZ
Year: 2011
Journal: J Immunol
Title: CD134 plus CD137 dual costimulation induces Eomesodermin in CD4 T cells to program cytotoxic Th1 differentiation.
Volume: 187
Issue: 7
Pages: 3555-64
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Publication
37963469 | J:343432
First Author: Liu Y
Year: 2023
Journal: Dev Cell
Title: A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression.
Volume: 58
Issue: 23
Pages: 2700-2717.e12
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Publication
22872574 | J:234392
First Author: Roberts PJ
Year: 2012
Journal: Clin Cancer Res
Title: Combined PI3K/mTOR and MEK inhibition provides broad antitumor activity in faithful murine cancer models.
Volume: 18
Issue: 19
Pages: 5290-303
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Publication
38510127 | J:346388
First Author: Kim U
Year: 2024
Journal: iScience
Title: ΔNp63 regulates MDSC survival and metabolism in triple-negative breast cancer.
Volume: 27
Issue: 4
Pages: 109366
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Publication
32665355 | J:296320
First Author: Bridges AE
Year: 2020
Journal: Cancer Res
Title: RAD51AP1 Deficiency Reduces Tumor Growth by Targeting Stem Cell Self-Renewal.
Volume: 80
Issue: 18
Pages: 3855-3866
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Publication
30526553 | J:308845
First Author: Homer-Bouthiette C
Year: 2018
Journal: BMC Cancer
Title: Deletion of the murine ortholog of the 8q24 gene desert has anti-cancer effects in transgenic mammary cancer models.
Volume: 18
Issue: 1
Pages: 1233
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Publication
36614200 | J:332518
 
First Author: Manna PR
Year: 2023
Journal: Int J Mol Sci
Title: Expression and Function of StAR in Cancerous and Non-Cancerous Human and Mouse Breast Tissues: New Insights into Diagnosis and Treatment of Hormone-Sensitive Breast Cancer.
Volume: 24
Issue: 1
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Publication
37943878 | J:342352
First Author: He A
Year: 2023
Journal: PLoS Biol
Title: Targeted inhibition of Wnt signaling with a Clostridioides difficile toxin B fragment suppresses breast cancer tumor growth.
Volume: 21
Issue: 11
Pages: e3002353
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Publication
24081141 | J:204993
First Author: Xiong Y
Year: 2013
Journal: J Biol Chem
Title: Sphingosine kinases are not required for inflammatory responses in macrophages.
Volume: 288
Issue: 45
Pages: 32563-73
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Publication
17909080 | J:130024
First Author: Zarek PE
Year: 2008
Journal: Blood
Title: A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells.
Volume: 111
Issue: 1
Pages: 251-9
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Publication
33964209 | J:307143
First Author: Cui C
Year: 2021
Journal: Cell
Title: Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis.
Volume: 184
Issue: 12
Pages: 3163-3177.e21
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Publication
37100836 | J:350043
First Author: Polzin A
Year: 2023
Journal: Nat Commun
Title: Revealing concealed cardioprotection by platelet Mfsd2b-released S1P in human and murine myocardial infarction.
Volume: 14
Issue: 1
Pages: 2404
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Publication
21852535 | J:174672
First Author: Ohhata T
Year: 2011
Journal: Genes Dev
Title: Lineage-specific function of the noncoding Tsix RNA for Xist repression and Xi reactivation in mice.
Volume: 25
Issue: 16
Pages: 1702-15
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Publication
38097610 | J:350044
First Author: Thomas N
Year: 2023
Journal: Nat Commun
Title: Sphingosine-1-phosphate suppresses GLUT activity through PP2A and counteracts hyperglycemia in diabetic red blood cells.
Volume: 14
Issue: 1
Pages: 8329
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Publication
32897877 | J:299980
First Author: Studstill CJ
Year: 2020
Journal: J Clin Invest
Title: Sphingosine kinase 2 restricts T cell immunopathology but permits viral persistence.
Volume: 130
Issue: 12
Pages: 6523-6538
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Publication
32645139 | J:312889
 
First Author: Chan IS
Year: 2020
Journal: J Cell Biol
Title: Cancer cells educate natural killer cells to a metastasis-promoting cell state.
Volume: 219
Issue: 9
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Publication
38039374 | J:343273
First Author: Cui J
Year: 2023
Journal: Sci Adv
Title: Targeting ABCA12-controlled ceramide homeostasis inhibits breast cancer stem cell function and chemoresistance.
Volume: 9
Issue: 48
Pages: eadh1891
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Publication
31676574 | J:283700
First Author: Georgess D
Year: 2020
Journal: Cancer Res
Title: Twist1-Induced Epithelial Dissemination Requires Prkd1 Signaling.
Volume: 80
Issue: 2
Pages: 204-218
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Publication
18614536 | J:142014
First Author: Ozawa Y
Year: 2008
Journal: J Biol Chem
Title: Roles of STAT3/SOCS3 pathway in regulating the visual function and ubiquitin-proteasome-dependent degradation of rhodopsin during retinal inflammation.
Volume: 283
Issue: 36
Pages: 24561-70
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Publication
25250575 | J:217617
First Author: Xiong Y
Year: 2014
Journal: J Clin Invest
Title: Erythrocyte-derived sphingosine 1-phosphate is essential for vascular development.
Volume: 124
Issue: 11
Pages: 4823-8
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Publication
32209471 | J:288320
First Author: Joshi JC
Year: 2020
Journal: Cell Rep
Title: SPHK2-Generated S1P in CD11b+ Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages.
Volume: 30
Issue: 12
Pages: 4096-4109.e5
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Publication
34544911 | J:335100
First Author: Hirata W
Year: 2022
Journal: Exp Anim
Title: Generation of the Y-chromosome linked red fluorescent protein transgenic mouse model and sexing at the preimplantation stage.
Volume: 71
Issue: 1
Pages: 82-89
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Genotype
Genotype
Symbol: C3/C3 Fcer1g/Fcer1g Tg(Ins2-TFRC/OVA)296Wehi/?
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: C3/C3 Fas/Fas
Background: involves: 129S4/SvJae * C57BL/6 * MRL
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: C3/C3 C4b/C4b Fas/Fas
Background: involves: 129S4/SvJae * C57BL/6 * MRL
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: C3/C3 Zbtb20/?
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Protein Coding Gene
MGI:104850 | Cd55
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0014552 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGI:88513 | Cr1l
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0015075 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGI:96208 | Hoxd4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0023674 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGI:1330832 | Masp2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0026804 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016434 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_129S1SvImJ_G0016968 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_129S1SvImJ_G0025852 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_129S1SvImJ_G0029128 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016417 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016947 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025830 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029093 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016382 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016912 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025798 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029041 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016377 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016905 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025824 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029109 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016203 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016729 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025584 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0028830 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_104850 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_88513 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_96208 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1330832 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0016837 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017368 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026271 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029558 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016312 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025048 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028243 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016175 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016703 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025565 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0028792 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016282 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016809 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025696 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0028941 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016281 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom