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Search results 2301 to 2400 out of 4514 for Cdc42

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Type Details Score
Publication
17663722 | J:132626
First Author: Hayashi T
Year: 2007
Journal: Genes Cells
Title: PX-RICS, a novel splicing variant of RICS, is a main isoform expressed during neural development.
Volume: 12
Issue: 8
Pages: 929-39
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Protein Coding Gene
MGI:88049 | Apoa1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
15289607 | J:91783
First Author: Caenepeel S
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: The mouse kinome: discovery and comparative genomics of all mouse protein kinases.
Volume: 101
Issue: 32
Pages: 11707-12
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Publication
22103416 | J:184159
First Author: Antypa M
Year: 2011
Journal: Eur J Neurosci
Title: Differential gene expression in migratory streams of cortical interneurons.
Volume: 34
Issue: 10
Pages: 1584-94
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Publication
11867214 | J:75291
First Author: Witherden AS
Year: 2002
Journal: Gene
Title: An integrated genetic, radiation hybrid, physical and transcription map of a region of distal mouse chromosome 12, including an imprinted locus and the 'Legs at odd angles' (Loa) mutation.
Volume: 283
Issue: 1-2
Pages: 71-82
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Protein
Q0KL02
Organism: Mus musculus/domesticus
Length: 3102  
Fragment?: false
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Publication
9135144 | J:39300
First Author: Su YC
Year: 1997
Journal: EMBO J
Title: NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain.
Volume: 16
Issue: 6
Pages: 1279-90
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GO Term
GO:0043547 | positive regulation of GTPase activity
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Protein
Q60992
Organism: Mus musculus/domesticus
Length: 868  
Fragment?: false
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Protein Coding Gene
MGI:2138281 | Lbr
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1927230 | Trio
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1929494 | Arhgap35
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1920591 | Arhgef6
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q3U9G9
Organism: Mus musculus/domesticus
Length: 626  
Fragment?: false
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Protein
Q91YM2
Organism: Mus musculus/domesticus
Length: 1499  
Fragment?: false
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Publication
17314132 | -
First Author: Luo T
Year: 2007
Journal: Development
Title: Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development.
Volume: 134
Issue: 7
Pages: 1279-89
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Protein
Q80VY2
Organism: Mus musculus/domesticus
Length: 300  
Fragment?: false
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Protein
Q9CX62
Organism: Mus musculus/domesticus
Length: 282  
Fragment?: false
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Protein
A0A0K2S4W3
Organism: Mus musculus/domesticus
Length: 169  
Fragment?: true
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Publication
26607847 | -
 
First Author: Baskaran Y
Year: 2015
Journal: Nat Commun
Title: An in cellulo-derived structure of PAK4 in complex with its inhibitor Inka1.
Volume: 6
Pages: 8681
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Publication
12900578 | -
First Author: Kutsche K
Year: 2002
Journal: Cytogenet Genome Res
Title: Microphthalmia with linear skin defects syndrome (MLS): a male with a mosaic paracentric inversion of Xp.
Volume: 99
Issue: 1-4
Pages: 297-302
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Publication
27713425 | -
 
First Author: Eccles RL
Year: 2016
Journal: Nat Commun
Title: Bimodal antagonism of PKA signalling by ARHGAP36.
Volume: 7
Pages: 12963
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Publication
12522145 | J:177167
First Author: Tomsig JL
Year: 2003
Journal: J Biol Chem
Title: Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.
Volume: 278
Issue: 12
Pages: 10048-54
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Publication
17430976 | J:124016
First Author: Millard TH
Year: 2007
Journal: J Cell Sci
Title: Characterisation of IRTKS, a novel IRSp53/MIM family actin regulator with distinct filament bundling properties.
Volume: 120
Issue: Pt 9
Pages: 1663-72
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Protein Coding Gene
MGI:106206 | Nrp1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q9R0C8
Organism: Mus musculus/domesticus
Length: 847  
Fragment?: false
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Protein
H3BJG7
Organism: Mus musculus/domesticus
Length: 163  
Fragment?: true
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Protein
A0A1W2P841
Organism: Mus musculus/domesticus
Length: 262  
Fragment?: true
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Protein
A0A1W2P7Y0
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
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Publication
23509069 | -
First Author: Zhu M
Year: 2013
Journal: J Cell Biol
Title: MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progression.
Volume: 200
Issue: 6
Pages: 773-87
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Publication
29679050 | -
First Author: Vodicska B
Year: 2018
Journal: Sci Rep
Title: MISP regulates the IQGAP1/Cdc42 complex to collectively orchestrate spindle orientation and mitotic progression.
Volume: 8
Issue: 1
Pages: 6330
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Protein Domain
IPR033360 | Tiam1
Type: Family
Description: T-lymphoma invasion and metastasis-inducing protein 1 (Tiam1) is a guanine exchange factor (GEF) for CDC42 and the Rho-family GTPase Rac1, which plays an important role in cell-matrix adhesion and in cell migration [, ]. Tiam1 is involved in multiple steps of tumorigenesis [].
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Protein Domain
IPR041852 | ARHGAP6_RhoGAP
Type: Domain
Description: This entry represent the RhoGAP domain found in ARHGAP6 and ARHGAP36.Rho GTPase activating protein 6 (ARHGAP6/RHOGAP6) shows GAP activity towards RhoA, but not towards Cdc42 and Rac1 []. ARHGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS); MLS is a severe X-linked developmental disorder []. ARHGAP36 is a potent antagonist of PKAsignalling [].
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Protein Domain
IPR031205 | PPP1R12C
Type: Family
Description: Protein phosphatase 1 regulatory subunit 12C (PPP1R12C, also known as p85) is a myotonic dystrophy kinase-related Cdc42 binding kinase (MRCK) substrate. It is associated with protein phosphatase 1delta (PP1delta) through its N terminus. This association is required for the regulation of both the catalytic activities and the assembly of actin cytoskeleton. Its C terminus is involved in dimerisation and interaction with other proteins [].
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Protein Domain
IPR029267 | FAM212
Type: Domain
Description: This entry represents a domain found in the Inka proteins, including Inka1 and Inka2. They are inhibitors of PAK4, a metazoan-specific kinase acting downstream of Cdc42 [, ]. Danio rerio (Zebrafish) Inka1 is required for the proper migration of neural crest cells during embryonic development [].
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Protein Domain
IPR039201 | Inka
Type: Family
Description: This entry includes INKA1 and INKA2. They are inhibitors of PAK4, a metazoan-specific kinase acting downstream of Cdc42 [, ]. Danio rerio (Zebrafish) Inka1 is required for the proper migration of neural crest cells during embryonic development []. Homologues are known only from chordates and contain a FAM212 domain.
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Protein Domain
IPR037863 | RHOGAP6/36
Type: Family
Description: Rho GTPase activating protein 6 (ArhGAP6/RHOGAP6) shows GAP activity towards RhoA, but not towards Cdc42 and Rac1 []. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS); MLS is a severe X-linked developmental disorder [].This family also includes ARHGAP36, which is a potent antagonist of PKA signalling [].
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Protein Domain
IPR042779 | MISP/MISP3
Type: Family
Description: This entry includes MISP/MISP3 from animals. MISP is an actin-binding protein that functions in spindle orientation probably by linking the astral microtubules (MTs) to the actin cytoskeleton [, ]. It has been shown to regulate IQGAP1 and Cdc42 to ensure proper mitotic progression and correct spindle orientation []. The function of MISP3 is not clear.
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Protein Domain
IPR035469 | DNMBP
Type: Family
Description: Dynamin-binding protein (DNMBP, also known as Tuba) is a scaffold protein that links dynamin with actin-regulating proteins. It binds a variety of actin regulatory proteins, including N-WASP, CR16, WAVE1, WIRE, PIR121, NAP1, and Ena/VASP proteins, via a C-terminal SH3 domain []. It plays a critical role in ciliogenesis and nephrogenesis, most likely via Cdc42 activation [].
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Protein Domain
IPR033235 | MRCK_gamma
Type: Family
Description: Serine/threonine-protein kinase MRCK (myotonic dystrophy kinase-related CDC42-binding kinase) is an serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in actin-myosin regulation and activities including cell adhesion, motility and invasion [, ]. Three isoforms have been described in mammals: alpha, beta and gamma [, ]. This entry represents the serine/threonine-protein kinase MRCK gamma [].
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Publication
18363964 | J:141607
First Author: Hayakawa M
Year: 2008
Journal: Genes Cells
Title: Novel insights into FGD3, a putative GEF for Cdc42, that undergoes SCF(FWD1/beta-TrCP)-mediated proteasomal degradation analogous to that of its homologue FGD1 but regulates cell morphology and motility differently from FGD1.
Volume: 13
Issue: 4
Pages: 329-42
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Protein Coding Gene
MGP_CAROLIEiJ_G0022060 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGI:2444227 | Rhov
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0024140 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0024211 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_129S1SvImJ_G0026339 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0024176 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026300 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0024145 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026279 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0024176 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026313 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023944 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026059 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_108054 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2444227 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024618 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026760 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023418 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025521 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023912 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026035 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0024044 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026174 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0024010 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026136 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0024125 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026275 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0024038 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026155 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024666 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026815 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0023162 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025257 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023482 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025590 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018794 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_PahariEiJ_G0025583 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0022971 | -
Type: protein_coding_gene
Organism: Mus spretus
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Protein Coding Gene
MGP_SPRETEiJ_G0025056 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10545207 | J:161040
First Author: Shao H
Year: 1999
Journal: Arch Biochem Biophys
Title: Biochemical characterization of the Ras-related GTPases Rit and Rin.
Volume: 371
Issue: 2
Pages: 207-19
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Publication
14662747 | J:233584
First Author: Hoshino M
Year: 2003
Journal: J Cell Biol
Title: Small GTPase Rin induces neurite outgrowth through Rac/Cdc42 and calmodulin in PC12 cells.
Volume: 163
Issue: 5
Pages: 1067-76
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GXD Expression
GXD Expression
 
Probe: MGI:1631136
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827750
Age: embryonic day 14.5
Image: euxassay_007060_02
Specimen Label: euxassay_007060_02
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1631136
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827750
Age: embryonic day 14.5
Image: euxassay_007060_03
Specimen Label: euxassay_007060_03
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:1631136
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827750
Age: embryonic day 14.5
Image: euxassay_007060_04
Specimen Label: euxassay_007060_04
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:1631136
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827750
Age: embryonic day 14.5
Image: euxassay_007060_05
Specimen Label: euxassay_007060_05
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:1631136
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827750
Age: embryonic day 14.5
Image: euxassay_007060_06
Specimen Label: euxassay_007060_06
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:1631136
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827750
Age: embryonic day 14.5
Image: euxassay_007060_07
Specimen Label: euxassay_007060_07
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:1631136
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827750
Age: embryonic day 14.5
Image: euxassay_007060_08
Specimen Label: euxassay_007060_08
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:1631136
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827750
Age: embryonic day 14.5
Image: euxassay_007060_09
Specimen Label: euxassay_007060_09
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:1631136
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827750
Age: embryonic day 14.5
Image: euxassay_007060_10
Specimen Label: euxassay_007060_10
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:1631136
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827750
Age: embryonic day 14.5
Image: euxassay_007060_11
Specimen Label: euxassay_007060_11
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:1631136
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827750
Age: embryonic day 14.5
Image: euxassay_007060_12
Specimen Label: euxassay_007060_12
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:1631136
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827750
Age: embryonic day 14.5
Image: euxassay_007060_13
Specimen Label: euxassay_007060_13
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:1631136
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827750
Age: embryonic day 14.5
Image: euxassay_007060_14
Specimen Label: euxassay_007060_14
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
 
Probe: MGI:1631136
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827750
Age: embryonic day 14.5
Image: euxassay_007060_15
Specimen Label: euxassay_007060_15
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:1631136
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827750
Age: embryonic day 14.5
Image: euxassay_007060_16
Specimen Label: euxassay_007060_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1631136
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827750
Age: embryonic day 14.5
Image: euxassay_007060_17
Specimen Label: euxassay_007060_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1631136
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827750
Age: embryonic day 14.5
Image: euxassay_007060_18
Specimen Label: euxassay_007060_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1631136
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827750
Age: embryonic day 14.5
Image: euxassay_007060_19
Specimen Label: euxassay_007060_19
Detected: true
Specimen Num: 19
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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