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Search results 2301 to 2400 out of 3068 for Ret

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Type Details Score
Strain
Attribute String: congenic, mutant strain, targeted mutation
Allele
Name: ret proto-oncogene; targeted mutation 2, David D Ginty
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Genotype
Symbol: Ret/Ret
Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Zygosity: hm
Has Mutant Allele: true
Interaction Experiment
Description: A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor.
Allele  
Name: ret proto-oncogene; wild type
Allele Type: Not Specified
Publication
First Author: Bonnefont J
Year: 2008
Journal: Am J Hum Genet
Title: Evolutionary forces shape the human RFPL1,2,3 genes toward a role in neocortex development.
Volume: 83
Issue: 2
Pages: 208-18
Publication
First Author: Volakakis N
Year: 2015
Journal: J Neurosci
Title: Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene Expression.
Volume: 35
Issue: 42
Pages: 14370-85
Publication
First Author: Wills MK
Year: 2017
Journal: J Biol Chem
Title: Signaling adaptor ShcD suppresses extracellular signal-regulated kinase (Erk) phosphorylation distal to the Ret and Trk neurotrophic receptors.
Volume: 292
Issue: 14
Pages: 5748-5759
Publication
First Author: Jmaeff S
Year: 2020
Journal: J Biol Chem
Title: Small-molecule agonists of the RET receptor tyrosine kinase activate biased trophic signals that are influenced by the presence of GFRa1 co-receptors.
Volume: 295
Issue: 19
Pages: 6532-6542
Publication
First Author: Li Y
Year: 2015
Journal: Hum Mol Genet
Title: SRY interference of normal regulation of the RET gene suggests a potential role of the Y-chromosome gene in sexual dimorphism in Hirschsprung disease.
Volume: 24
Issue: 3
Pages: 685-97
Genotype
Symbol: Ret/Ret<+>
Background: involves: 129S1/Sv * C57BL/6J * FVB/N
Zygosity: ht
Has Mutant Allele: true
Regulatory Region
Type: enhancer
Organism: mouse, laboratory
Publication
First Author: Michiels FM
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Development of medullary thyroid carcinoma in transgenic mice expressing the RET protooncogene altered by a multiple endocrine neoplasia type 2A mutation.
Volume: 94
Issue: 7
Pages: 3330-5
Genotype
Symbol: Ret/Ret<+>
Background: involves: C57BL/6
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Goodman KM
Year: 2014
Journal: Cell Rep
Title: RET recognition of GDNF-GFRα1 ligand by a composite binding site promotes membrane-proximal self-association.
Volume: 8
Issue: 6
Pages: 1894-1904
Interaction Experiment
Description: The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells.
Allele
Name: ret proto-oncogene; targeted mutation 1, Frank Costantini
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: ret proto-oncogene; targeted mutation 2, Frank Costantini
Allele Type: Targeted
Attribute String: Humanized sequence
Allele
Name: ret proto-oncogene; targeted mutation 1, Vassilis Pachnis
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: ret proto-oncogene; targeted mutation 2, Vassilis Pachnis
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
Allele    
Name: ret finger protein-like 4; wild type
Allele
Name: ret proto-oncogene; targeted mutation 1, Jeffrey Milbrandt
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele  
Name: ret proto-oncogene; targeted mutation 1, Masahide Takahashi
Allele Type: Targeted
Allele
Name: ret proto-oncogene; targeted mutation 2, Jeffrey Milbrandt
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: ret proto-oncogene; targeted mutation 3.1, Jeffrey Milbrandt
Allele Type: Targeted
Attribute String: Dominant negative
Allele  
Name: ret proto-oncogene; targeted mutation 3, Jeffrey Milbrandt
Allele Type: Targeted
Allele
Name: ret proto-oncogene; targeted mutation 3, Vassilis Pachnis
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: ret proto-oncogene; targeted mutation 4, Vassilis Pachnis
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: ret proto-oncogene; targeted mutation 5, Vassilis Pachnis
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
Allele  
Name: ret proto-oncogene; targeted mutation 4, Jeffrey Milbrandt
Allele Type: Targeted
Allele
Name: ret proto-oncogene; targeted mutation 5, Jeffrey Milbrandt
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout
Allele
Name: ret proto-oncogene; targeted mutation 6, Jeffrey Milbrandt
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout
Allele  
Name: ret proto-oncogene; targeted mutation 7, Jeffrey Milbrandt
Allele Type: Targeted
Allele  
Name: ret proto-oncogene; targeted mutation 8, Jeffrey Milbrandt
Allele Type: Targeted
Allele  
Name: ret proto-oncogene; targeted mutation 9, Jeffrey Milbrandt
Allele Type: Targeted
Allele  
Name: ret proto-oncogene; targeted mutation 10, Jeffrey Milbrandt
Allele Type: Targeted
Allele  
Name: ret proto-oncogene; targeted mutation 11, Jeffrey Milbrandt
Allele Type: Targeted
Allele  
Name: ret proto-oncogene; targeted mutation 12, Jeffrey Milbrandt
Allele Type: Targeted
Allele
Name: ret proto-oncogene; targeted mutation 1, Cristiana Carniti
Allele Type: Targeted
Attribute String: Humanized sequence, Null/knockout
Allele
Name: ret proto-oncogene; targeted mutation 1.1, Rudiger Klein
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: ret proto-oncogene; targeted mutation 1, Rudiger Klein
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: ret proto-oncogene; targeted mutation 13, Jeffrey Milbrandt
Allele Type: Targeted
Attribute String: Inserted expressed sequence
Allele
Name: ret proto-oncogene; targeted mutation 3, Frank Costantini
Allele Type: Targeted
Attribute String: Not Specified
Allele  
Name: ret proto-oncogene; targeted mutation 14, Jeffrey Milbrandt
Allele Type: Targeted
Allele
Name: ret proto-oncogene; targeted mutation 1, Hideki Enomoto
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele  
Name: ret proto-oncogene; targeted mutation 1, Giovanni Romeo
Allele Type: Targeted
Allele  
Name: ret finger protein-like 4B; wild type
Allele Type: Not Specified
Allele
Name: ret proto-oncogene; targeted mutation 1.1, Patrik Ernfors
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: ret proto-oncogene; targeted mutation 1.2, Patrik Ernfors
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: ret proto-oncogene; targeted mutation 3.1, Hideki Enomoto
Allele Type: Targeted
Attribute String: Inserted expressed sequence
Allele
Name: ret proto-oncogene; targeted mutation 6.1, Vassilis Pachnis
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: ret proto-oncogene; targeted mutation 6.2, Vassilis Pachnis
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: ret proto-oncogene; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: ret proto-oncogene; endonuclease-mediated mutation 2, Hideki Enomoto
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
Allele
Name: ret proto-oncogene; endonuclease-mediated mutation 3, Hideki Enomoto
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
Allele
Name: ret proto-oncogene; endonuclease-mediated mutation 4, Hideki Enomoto
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
Allele
Name: ret proto-oncogene; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
GXD Expression  
Probe: MGI:7471444
Assay Type: RNA in situ
Annotation Date: 2023-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7481265
Age: postnatal day 14
Note: Segregation of neurons expressing TrkA from those expressing Ret nearly complete.
Specimen Label: 1A P14
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:7471446
Assay Type: RNA in situ
Annotation Date: 2023-05-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1666828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7481268
Age: postnatal day 14
Note: Weak expression in Gfra2 expressing neurons. Overlap with Ret expression in 18.2% of cells.
Specimen Label: 1B
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7471447
Assay Type: RNA in situ
Annotation Date: 2023-05-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1666828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7481271
Age: postnatal day 14
Note: Strong expression in Gfra2 expressing neurons. Overlap with Ret expression in 61.4% of cells.
Specimen Label: 1C
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7471448
Assay Type: RNA in situ
Annotation Date: 2023-05-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1666828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7481274
Age: postnatal day 14
Note: Weak expression in Gfra2 expressing neurons. Overlap with Ret expression in 13.9% of cells.
Specimen Label: 1D
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7471447
Assay Type: RNA in situ
Annotation Date: 2023-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666827
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7481273
Age: postnatal day 2
Note: Weak expression in Gfra2 expressing neurons. Overlap with Ret expression in 13.9% of cells.
Specimen Label: S6D
Detected: true
Specimen Num: 10
Genotype
Symbol: Ret/Ret<+>
Background: involves: 129/Sv * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 457  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 306  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 331  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 325  
Fragment?: false
Publication
First Author: Itier JM
Year: 1998
Journal: Nature
Title: Imprinted gene in postnatal growth role.
Volume: 393
Issue: 6681
Pages: 125-6
Protein
Organism: Mus musculus/domesticus
Length: 513  
Fragment?: false
Publication
First Author: Tezel G
Year: 1999
Journal: Pathol Int
Title: Different nuclear/cytoplasmic distributions of RET finger protein in different cell types.
Volume: 49
Issue: 10
Pages: 881-6
Publication
First Author: Tezel G
Year: 2002
Journal: Pathol Int
Title: Differential expression of RET finger protein in testicular germ cell tumors.
Volume: 52
Issue: 10
Pages: 623-7
Publication
First Author: Horio M
Year: 2012
Journal: Cancer Med
Title: Expression of RET finger protein predicts chemoresistance in epithelial ovarian cancer.
Volume: 1
Issue: 2
Pages: 218-29
Genotype
Symbol: Ret/Ret<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Ret/Ret
Background: involves: 129S/Sv * C57BL/6 * FVB/N
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Ret/Ret<+>
Background: involves: 129 * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Vargiolu M
Year: 2009
Journal: J Clin Endocrinol Metab
Title: The tyrosine kinase receptor RET interacts in vivo with aryl hydrocarbon receptor-interacting protein to alter survivin availability.
Volume: 94
Issue: 7
Pages: 2571-8
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Transgene
Type: transgene
Organism: mouse, laboratory
Strain
Attribute String: targeted mutation, mutant strain
Strain
Attribute String: targeted mutation, mutant strain, congenic
Strain
Attribute String: mutant strain, congenic, targeted mutation
Strain
Attribute String: Not specified
Strain
Attribute String: Not specified
Strain
Attribute String: mutant stock, targeted mutation
Strain
Attribute String: targeted mutation, mutant strain, congenic
Strain
Attribute String: targeted mutation, mutant stock
Strain
Attribute String: congenic, targeted mutation
Allele
Name: ret proto-oncogene; targeted mutation 1, David D Ginty
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: ret proto-oncogene; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Allele
Name: ret proto-oncogene; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: ret proto-oncogene; targeted mutation 1.2, David D Ginty
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: ret finger protein-like 4B; endonuclease-mediated mutation 12, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: ret proto-oncogene; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Allele
Name: ret proto-oncogene; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain