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Search results 2301 to 2400 out of 2720 for Runx2

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Type Details Score
Publication
35270044 | J:327471
 
First Author: Steppe L
Year: 2022
Journal: Int J Mol Sci
Title: Bone Mass and Osteoblast Activity Are Sex-Dependent in Mice Lacking the Estrogen Receptor α in Chondrocytes and Osteoblast Progenitor Cells.
Volume: 23
Issue: 5
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Genotype
Genotype
Symbol: Phox2b/Phox2b<+> Twist1/Twist1
Background: involves: C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Phox2b/Phox2b Twist1/Twist1
Background: involves: C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Protein Coding Gene
MGI:1891731 | Stub1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:894293 | Smad4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:88313 | Ccnd1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:88064 | Ar
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P25322
Organism: Mus musculus/domesticus
Length: 295  
Fragment?: false
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Protein
Q9WUD1
Organism: Mus musculus/domesticus
Length: 304  
Fragment?: false
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Protein
P19091
Organism: Mus musculus/domesticus
Length: 899  
Fragment?: false
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Protein
P97471
Organism: Mus musculus/domesticus
Length: 551  
Fragment?: false
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Publication
33180356 | J:360243
First Author: Hendrickx G
Year: 2021
Journal: J Bone Miner Res
Title: Piezo1 Inactivation in Chondrocytes Impairs Trabecular Bone Formation.
Volume: 36
Issue: 2
Pages: 369-384
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HT Experiment
GSE149869 | Transient and lineage-restricted requirement of Ebf3 for sternum ossification
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE196628 | Deletion of Tfam in Prx1-Cre expressing limb mesenchyme results in spontaneous bone fractures
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
34793446 | J:314704
First Author: Liao N
Year: 2021
Journal: PLoS One
Title: Osteoblast-specific inactivation of p53 results in locally increased bone formation.
Volume: 16
Issue: 11
Pages: e0249894
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Publication
29949664 | J:359760
First Author: Scholtysek C
Year: 2018
Journal: J Bone Miner Res
Title: NR4A1 Regulates Motility of Osteoclast Precursors and Serves as Target for the Modulation of Systemic Bone Turnover.
Volume: 33
Issue: 11
Pages: 2035-2047
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Publication
27102824 | J:235524
 
First Author: Yorgan T
Year: 2016
Journal: Bone
Title: Osteoblast-specific Notch2 inactivation causes increased trabecular bone mass at specific sites of the appendicular skeleton.
Volume: 87
Pages: 136-46
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Publication
36246887 | J:335314
 
First Author: Bülow JM
Year: 2022
Journal: Front Endocrinol (Lausanne)
Title: Complement receptor C5aR1 on osteoblasts regulates osteoclastogenesis in experimental postmenopausal osteoporosis.
Volume: 13
Pages: 1016057
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Publication
32439961 | J:292608
First Author: Müller DIH
Year: 2020
Journal: Sci Rep
Title: PPARδ-mediated mitochondrial rewiring of osteoblasts determines bone mass.
Volume: 10
Issue: 1
Pages: 8428
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Publication
37178987 | J:338934
 
First Author: Besio R
Year: 2023
Journal: Matrix Biol
Title: CaMKII inhibition due to TRIC-B loss-of-function dysregulates SMAD signaling in osteogenesis imperfecta.
Volume: 120
Pages: 43-59
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Publication
35068191 | J:337389
First Author: Nilsson KH
Year: 2022
Journal: Am J Physiol Endocrinol Metab
Title: Estradiol and RSPO3 regulate vertebral trabecular bone mass independent of each other.
Volume: 322
Issue: 3
Pages: E211-E218
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(Runx2-icre)1Jtuc/?
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nr3c1/Nr3c1 Tg(Runx2-icre)1Jtuc/?
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Runx2-icre)1Jtuc/?
Background: involves: FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dicer1/Dicer1 Tg(Runx2-icre)1Jtuc/?
Background: involves: FVB/N
Zygosity: cn
Has Mutant Allele: true
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Protein Coding Gene
MGI:88357 | Cdk4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1351663 | Skp2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q08024
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: false
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Protein
P30285
Organism: Mus musculus/domesticus
Length: 303  
Fragment?: false
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Protein
Q9Z0Z3
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: false
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Publication
16298332 | J:103985
First Author: Naganawa T
Year: 2006
Journal: Biochem Biophys Res Commun
Title: In vivo and in vitro comparison of the effects of FGF-2 null and haplo-insufficiency on bone formation in mice.
Volume: 339
Issue: 2
Pages: 490-8
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Publication
24444608 | J:206440
First Author: Kokabu S
Year: 2014
Journal: FEBS Lett
Title: Expression of TLE3 by bone marrow stromal cells is regulated by canonical Wnt signaling.
Volume: 588
Issue: 4
Pages: 614-9
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Protein
Q5NCY0
Organism: Mus musculus/domesticus
Length: 1641  
Fragment?: false
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Publication
29621230 | J:261326
First Author: Hendrickx G
Year: 2018
Journal: PLoS Genet
Title: Conditional mouse models support the role of SLC39A14 (ZIP14) in Hyperostosis Cranialis Interna and in bone homeostasis.
Volume: 14
Issue: 4
Pages: e1007321
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Publication
30361264 | J:295148
 
First Author: Linder M
Year: 2018
Journal: EMBO Mol Med
Title: EGFR is required for FOS-dependent bone tumor development via RSK2/CREB signaling.
Volume: 10
Issue: 11
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Publication
20732316 | J:165721
First Author: Krawchuk D
Year: 2010
Journal: Dev Biol
Title: Twist1 activity thresholds define multiple functions in limb development.
Volume: 347
Issue: 1
Pages: 133-46
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Publication
31675485 | J:298636
First Author: Conaway HH
Year: 2019
Journal: FASEB J
Title: Glucocorticoids employ the monomeric glucocorticoid receptor to potentiate vitamin D3 and parathyroid hormone-induced osteoclastogenesis.
Volume: 33
Issue: 12
Pages: 14394-14409
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Publication
29445126 | J:268761
First Author: Linder M
Year: 2018
Journal: Cell Death Differ
Title: EGFR controls bone development by negatively regulating mTOR-signaling during osteoblast differentiation.
Volume: 25
Issue: 6
Pages: 1094-1106
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Publication
34389713 | J:314349
First Author: Nilsson KH
Year: 2021
Journal: Nat Commun
Title: RSPO3 is important for trabecular bone and fracture risk in mice and humans.
Volume: 12
Issue: 1
Pages: 4923
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Publication
28991228 | J:257886
First Author: Lee S
Year: 2018
Journal: Oncogene
Title: Deletion of Menin in craniofacial osteogenic cells in mice elicits development of mandibular ossifying fibroma.
Volume: 37
Issue: 5
Pages: 616-626
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Publication
29561836 | J:261043
First Author: Chan WL
Year: 2018
Journal: PLoS Genet
Title: Impaired proteoglycan glycosylation, elevated TGF-β signaling, and abnormal osteoblast differentiation as the basis for bone fragility in a mouse model for gerodermia osteodysplastica.
Volume: 14
Issue: 3
Pages: e1007242
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Publication
25306233 | J:227816
First Author: Movérare-Skrtic S
Year: 2014
Journal: Nat Med
Title: Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures.
Volume: 20
Issue: 11
Pages: 1279-88
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Publication
36321691 | J:331417
   
First Author: Nagano K
Year: 2022
Journal: Elife
Title: R-spondin 3 deletion induces Erk phosphorylation to enhance Wnt signaling and promote bone formation in the appendicular skeleton.
Volume: 11
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Runx2-icre)1Jtuc/?
Background: involves: 129S4/SvJaeSor * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Protein Coding Gene
MGI:88302 | Ccnb1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P24860
Organism: Mus musculus/domesticus
Length: 430  
Fragment?: false
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Publication
31307226 | J:291735
First Author: Movérare-Skrtic S
Year: 2019
Journal: FASEB J
Title: Osteoblast-derived NOTUM reduces cortical bone mass in mice and the NOTUM locus is associated with bone mineral density in humans.
Volume: 33
Issue: 10
Pages: 11163-11179
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Publication
20826535 | J:165810
First Author: Zhang Z
Year: 2010
Journal: Development
Title: Preaxial polydactyly: interactions among ETV, TWIST1 and HAND2 control anterior-posterior patterning of the limb.
Volume: 137
Issue: 20
Pages: 3417-26
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Publication
24934156 | J:215793
First Author: Obri A
Year: 2014
Journal: J Cell Biol
Title: HDAC4 integrates PTH and sympathetic signaling in osteoblasts.
Volume: 205
Issue: 6
Pages: 771-80
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Publication
18430783 | J:139790
First Author: Sakamoto K
Year: 2008
Journal: J Cell Sci
Title: Zfp64 participates in Notch signaling and regulates differentiation in mesenchymal cells.
Volume: 121
Issue: Pt 10
Pages: 1613-23
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Publication
22421045 | J:183084
First Author: Dy P
Year: 2012
Journal: Dev Cell
Title: Sox9 directs hypertrophic maturation and blocks osteoblast differentiation of growth plate chondrocytes.
Volume: 22
Issue: 3
Pages: 597-609
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Publication
20643353 | J:162626
First Author: Zhou Z
Year: 2010
Journal: Dev Cell
Title: Neogenin regulation of BMP-induced canonical Smad signaling and endochondral bone formation.
Volume: 19
Issue: 1
Pages: 90-102
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Publication
29858571 | J:266313
First Author: Yang R
Year: 2018
Journal: Nat Commun
Title: Tet1 and Tet2 maintain mesenchymal stem cell homeostasis via demethylation of the P2rX7 promoter.
Volume: 9
Issue: 1
Pages: 2143
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Publication
27193062 | J:262503
 
First Author: Adhikari K
Year: 2016
Journal: Nat Commun
Title: A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation.
Volume: 7
Pages: 11616
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Publication
18477452 | J:135169
First Author: Ohba S
Year: 2008
Journal: Dev Cell
Title: Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity.
Volume: 14
Issue: 5
Pages: 689-99
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Publication
16533949 | J:107915
First Author: Lengner CJ
Year: 2006
Journal: J Cell Biol
Title: Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling.
Volume: 172
Issue: 6
Pages: 909-21
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Publication
18297084 | J:133658
First Author: Engin F
Year: 2008
Journal: Nat Med
Title: Dimorphic effects of Notch signaling in bone homeostasis.
Volume: 14
Issue: 3
Pages: 299-305
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Publication
14769860 | J:88126
First Author: Kenner L
Year: 2004
Journal: J Cell Biol
Title: Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects.
Volume: 164
Issue: 4
Pages: 613-23
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Publication
31253842 | J:276908
First Author: Huang J
Year: 2019
Journal: Nat Commun
Title: The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression.
Volume: 10
Issue: 1
Pages: 2876
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Publication
25389289 | J:218396
First Author: Bradley EW
Year: 2015
Journal: J Biol Chem
Title: Histone deacetylase 7 (Hdac7) suppresses chondrocyte proliferation and β-catenin activity during endochondral ossification.
Volume: 290
Issue: 1
Pages: 118-26
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Publication
27800612 | J:330666
First Author: Kim WJ
Year: 2017
Journal: J Cell Physiol
Title: Direct Delivery of Recombinant Pin1 Protein Rescued Osteoblast Differentiation of Pin1-Deficient Cells.
Volume: 232
Issue: 10
Pages: 2798-2805
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Publication
24616223 | J:215814
First Author: Kim JH
Year: 2014
Journal: J Cell Biol
Title: Kruppel-like factor 4 attenuates osteoblast formation, function, and cross talk with osteoclasts.
Volume: 204
Issue: 6
Pages: 1063-74
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Publication
27479603 | J:238565
First Author: Tang Y
Year: 2016
Journal: Nat Cell Biol
Title: Snail/Slug binding interactions with YAP/TAZ control skeletal stem cell self-renewal and differentiation.
Volume: 18
Issue: 9
Pages: 917-29
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Publication
24823376 | J:213582
First Author: Ono N
Year: 2014
Journal: Dev Cell
Title: Vasculature-associated cells expressing nestin in developing bones encompass early cells in the osteoblast and endothelial lineage.
Volume: 29
Issue: 3
Pages: 330-9
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Publication
30181118 | J:266454
 
First Author: Guo YC
Year: 2018
Journal: EMBO J
Title: Ubiquitin-specific protease USP34 controls osteogenic differentiation and bone formation by regulating BMP2 signaling.
Volume: 37
Issue: 20
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Publication
31968603 | J:297869
 
First Author: Takebe H
Year: 2020
Journal: Int J Mol Sci
Title: Sonic Hedgehog Regulates Bone Fracture Healing.
Volume: 21
Issue: 2
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Publication
21873211 | J:175218
First Author: Xie X
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Nuclear receptor chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) modulates mesenchymal cell commitment and differentiation.
Volume: 108
Issue: 36
Pages: 14843-8
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Publication
20951345 | J:166058
First Author: Correa D
Year: 2010
Journal: Dev Cell
Title: Zfp521 is a target gene and key effector of parathyroid hormone-related peptide signaling in growth plate chondrocytes.
Volume: 19
Issue: 4
Pages: 533-46
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Publication
35788130 | J:338744
First Author: Lai Y
Year: 2022
Journal: Int J Oral Sci
Title: Kindlin-2 loss in condylar chondrocytes causes spontaneous osteoarthritic lesions in the temporomandibular joint in mice.
Volume: 14
Issue: 1
Pages: 33
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Publication
30718470 | J:294975
First Author: Shin Y
Year: 2019
Journal: Cell Death Dis
Title: CYTL1 regulates bone homeostasis in mice by modulating osteogenesis of mesenchymal stem cells and osteoclastogenesis of bone marrow-derived macrophages.
Volume: 10
Issue: 2
Pages: 47
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Publication
33417921 | J:306698
First Author: Kerr BA
Year: 2021
Journal: Exp Cell Res
Title: Kindlin-3 mutation in mesenchymal stem cells results in enhanced chondrogenesis.
Volume: 399
Issue: 2
Pages: 112456
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Publication
35803931 | J:326767
First Author: Kim P
Year: 2022
Journal: Nat Commun
Title: Mast4 determines the cell fate of MSCs for bone and cartilage development.
Volume: 13
Issue: 1
Pages: 3960
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Publication
22065775 | J:180172
First Author: Goloudina AR
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Wip1 promotes RUNX2-dependent apoptosis in p53-negative tumors and protects normal tissues during treatment with anticancer agents.
Volume: 109
Issue: 2
Pages: E68-75
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Publication
22484461 | J:189443
First Author: Yoshida K
Year: 2012
Journal: Mol Cell Endocrinol
Title: PKR plays a positive role in osteoblast differentiation by regulating GSK-3β activity through a β-catenin-independent pathway.
Volume: 361
Issue: 1-2
Pages: 99-105
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Publication
25727319 | J:219944
First Author: Sun SS
Year: 2015
Journal: Cancer Lett
Title: Role of runt-related transcription factor 2 in signal network of tumors as an inter-mediator.
Volume: 361
Issue: 1
Pages: 1-7
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Publication
25514036 | J:220365
First Author: Fujioka K
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Inhibition of osteoclastogenesis by osteoblast-like cells genetically engineered to produce interleukin-10.
Volume: 456
Issue: 3
Pages: 785-91
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Publication
26302267 | J:229423
First Author: Koyama T
Year: 2015
Journal: Exp Cell Res
Title: Global increase in O-linked N-acetylglucosamine modification promotes osteoblast differentiation.
Volume: 338
Issue: 2
Pages: 194-202
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Publication
25447540 | J:234391
First Author: Zhou J
Year: 2015
Journal: Biochim Biophys Acta
Title: Mitogen-activated protein kinase p38 induces HDAC4 degradation in hypertrophic chondrocytes.
Volume: 1853
Issue: 2
Pages: 370-376
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Publication
31160553 | J:277820
First Author: Mokuda S
Year: 2019
Journal: Nat Commun
Title: Wwp2 maintains cartilage homeostasis through regulation of Adamts5.
Volume: 10
Issue: 1
Pages: 2429
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Publication
32111827 | J:286749
First Author: Wang X
Year: 2020
Journal: Nat Commun
Title: Targeting the CK1α/CBX4 axis for metastasis in osteosarcoma.
Volume: 11
Issue: 1
Pages: 1141
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Publication
31924749 | J:297868
First Author: Li P
Year: 2020
Journal: Cell Death Dis
Title: Loss of PARP-1 attenuates diabetic arteriosclerotic calcification via Stat1/Runx2 axis.
Volume: 11
Issue: 1
Pages: 22
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Publication
36914141 | J:334479
     
First Author: Wietecha MS
Year: 2023
Journal: Matrix Biol
Title: Phase-specific signatures of wound fibroblasts and matrix patterns define cancer-associated fibroblast subtypes.
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Protein Coding Gene
MGI:88351 | Cdk1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1891829 | Rbx1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P11440
Organism: Mus musculus/domesticus
Length: 297  
Fragment?: false
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Protein
P62878
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: false
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Publication
23555309 | J:195264
First Author: Vincentz JW
Year: 2013
Journal: PLoS Genet
Title: Twist1 controls a cell-specification switch governing cell fate decisions within the cardiac neural crest.
Volume: 9
Issue: 3
Pages: e1003405
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Publication
20519123 | J:160669
First Author: Rauch A
Year: 2010
Journal: Cell Metab
Title: Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor.
Volume: 11
Issue: 6
Pages: 517-31
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Publication
28106886 | J:258533
First Author: Liu P
Year: 2017
Journal: Cell Death Differ
Title: Loss of menin in osteoblast lineage affects osteocyte-osteoclast crosstalk causing osteoporosis.
Volume: 24
Issue: 4
Pages: 672-682
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Publication
30404864 | J:267451
 
First Author: Luther J
Year: 2018
Journal: Sci Transl Med
Title: Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand.
Volume: 10
Issue: 466
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Publication
31202927 | J:281175
 
First Author: Yorgan TA
Year: 2019
Journal: Bone
Title: Osteoblast-specific expression of Panx3 is dispensable for postnatal bone remodeling.
Volume: 127
Pages: 155-163
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Protein Coding Gene
MGI:102672 | Runx3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:103575 | Skp1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1349658 | Cul1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q9WTX6
Organism: Mus musculus/domesticus
Length: 776  
Fragment?: false
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Protein
Q9WTX5
Organism: Mus musculus/domesticus
Length: 163  
Fragment?: false
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Publication
19232401 | J:148804
First Author: Yu VW
Year: 2009
Journal: Gene Expr Patterns
Title: FIAT is co-expressed with its dimerization target ATF4 in early osteoblasts, but not in osteocytes.
Volume: 9
Issue: 5
Pages: 335-40
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Publication
25892096 | J:231357
First Author: Koide H
Year: 2015
Journal: J Bone Miner Res
Title: Mice Deficient in AKAP13 (BRX) Are Osteoporotic and Have Impaired Osteogenesis.
Volume: 30
Issue: 10
Pages: 1887-95
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Publication
15383550 | J:94905
First Author: Kim YJ
Year: 2004
Journal: J Biol Chem
Title: Bone morphogenetic protein-2-induced alkaline phosphatase expression is stimulated by Dlx5 and repressed by Msx2.
Volume: 279
Issue: 49
Pages: 50773-80
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Publication
16421188 | J:105923
First Author: Provot S
Year: 2006
Journal: Development
Title: Nkx3.2/Bapx1 acts as a negative regulator of chondrocyte maturation.
Volume: 133
Issue: 4
Pages: 651-62
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