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Search results 2401 to 2500 out of 2731 for Akt1

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Type Details Score
Allele
Akt1s1<Gt(OST274185)Lex> | MGI:4259333
 
Name: AKT1 substrate 1; gene trap OST274185, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(OST433713)Lex> | MGI:4315644
 
Name: AKT1 substrate 1; gene trap OST433713, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(OST438786)Lex> | MGI:4317451
 
Name: AKT1 substrate 1; gene trap OST438786, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(W084E06)Wrst> | MGI:4337518
 
Name: AKT1 substrate 1; gene trap W084E06, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(E276D07)Wrst> | MGI:4352162
 
Name: AKT1 substrate 1; gene trap E276D07, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(EUCE00143a07)Hmgu> | MGI:4372209
 
Name: AKT1 substrate 1; gene trap EUCE00143a07, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(EUCE0199g07)Hmgu> | MGI:4374073
 
Name: AKT1 substrate 1; gene trap EUCE0199g07, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(EUCE00143b07)Hmgu> | MGI:4380526
 
Name: AKT1 substrate 1; gene trap EUCE00143b07, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(EUCE0247f01)Hmgu> | MGI:4387539
 
Name: AKT1 substrate 1; gene trap EUCE0247f01, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(EUCE0170e04)Hmgu> | MGI:4391969
 
Name: AKT1 substrate 1; gene trap EUCE0170e04, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(EUCE0244e07)Hmgu> | MGI:4394361
 
Name: AKT1 substrate 1; gene trap EUCE0244e07, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(EUCE00116c09)Hmgu> | MGI:4396250
 
Name: AKT1 substrate 1; gene trap EUCE00116c09, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Akt1s1<tm1a(EUCOMM)Wtsi> | MGI:4431959
Name: AKT1 substrate 1; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Akt1s1<tm1e(EUCOMM)Wtsi> | MGI:4434185
Name: AKT1 substrate 1; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Akt1s1<tm1b(EUCOMM)Wtsi> | MGI:5548546
Name: AKT1 substrate 1; targeted mutation 1b, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Akt1s1<tm1.1Rrth> | MGI:5769980
Name: AKT1 substrate 1; targeted mutation 1.1, Richard Roth
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Akt1s1<em1Smoc> | MGI:7288217
Name: AKT1 substrate 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Akt1s1<em1Gpt> | MGI:7482216
Name: AKT1 substrate 1; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
22798428 | J:205385
First Author: Menges CW
Year: 2012
Journal: Mol Cancer Res
Title: Group I p21-activated kinases (PAKs) promote tumor cell proliferation and survival through the AKT1 and Raf-MAPK pathways.
Volume: 10
Issue: 9
Pages: 1178-88
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Pathway
R-MMU-8849469 | PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1
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Publication
25688191 | J:242395
 
First Author: Huang CH
Year: 2014
Journal: Front Behav Neurosci
Title: Investigation of gene effects and epistatic interactions between Akt1 and neuregulin 1 in the regulation of behavioral phenotypes and social functions in genetic mouse models of schizophrenia.
Volume: 8
Pages: 455
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Allele
Akt1<em1Smoc> | MGI:7288215
Name: thymoma viral proto-oncogene 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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HT Experiment
E-MEXP-891 | Transcription profiling by array of mammary gland from Akt1 knock-out mice
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-39699 | gene expression signatures of Akt1 +/- mice at 8weeks and 35weeks
Series Id: GSE39699
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
21432781 | -
First Author: Heron-Milhavet L
Year: 2011
Journal: Histol Histopathol
Title: Akt1 and Akt2: differentiating the aktion.
Volume: 26
Issue: 5
Pages: 651-62
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Publication
12150925 | -
First Author: Kim DH
Year: 2002
Journal: Cell
Title: mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.
Volume: 110
Issue: 2
Pages: 163-75
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Publication
32268790 | J:317841
First Author: Huang J
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: Endothelial Scaffolding Protein ENH (Enigma Homolog Protein) Promotes PHLPP2 (Pleckstrin Homology Domain and Leucine-Rich Repeat Protein Phosphatase 2)-Mediated Dephosphorylation of AKT1 and eNOS (Endothelial NO Synthase) Promoting Vascular Remodeling.
Volume: 40
Issue: 7
Pages: 1705-1721
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Publication
20413648 | -
First Author: Pyo YJ
Year: 2010
Journal: Plant Physiol
Title: High-affinity K(+) transport in Arabidopsis: AtHAK5 and AKT1 are vital for seedling establishment and postgermination growth under low-potassium conditions.
Volume: 153
Issue: 2
Pages: 863-75
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Allele
Akt1s1<Gt(IST10040A6)Tigm> | MGI:3925780
 
Name: AKT1 substrate 1; gene trap IST10040A6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(IST12475G4)Tigm> | MGI:4072085
 
Name: AKT1 substrate 1; gene trap IST12475G4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(IST12479D7)Tigm> | MGI:4072088
 
Name: AKT1 substrate 1; gene trap IST12479D7, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(IST12477H3)Tigm> | MGI:4073222
 
Name: AKT1 substrate 1; gene trap IST12477H3, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(IST12477G3)Tigm> | MGI:4074420
 
Name: AKT1 substrate 1; gene trap IST12477G3, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Strain
MGI:5518846 | C57BL/6N-Akt1s1<tm1a(EUCOMM)Wtsi>/Mmucd
Attribute String: targeted mutation, mutant strain, coisogenic
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Strain
MGI:5557214 | C57BL/6NTac-Akt1s1<tm1a(EUCOMM)Wtsi>/WtsiH
Attribute String: coisogenic, targeted mutation, mutant strain
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Allele
Akt1s1<Gt(IST11565F5)Tigm> | MGI:5148657
 
Name: AKT1 substrate 1; gene trap IST11565F5, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(IST13324D5)Tigm> | MGI:5159372
 
Name: AKT1 substrate 1; gene trap IST13324D5, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(IST13324D6)Tigm> | MGI:5159373
 
Name: AKT1 substrate 1; gene trap IST13324D6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(IST13220D12)Tigm> | MGI:5162789
 
Name: AKT1 substrate 1; gene trap IST13220D12, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(IST13758D7)Tigm> | MGI:5191090
 
Name: AKT1 substrate 1; gene trap IST13758D7, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(IST14229D9)Tigm> | MGI:5217727
 
Name: AKT1 substrate 1; gene trap IST14229D9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(IST14520D7)Tigm> | MGI:5242766
 
Name: AKT1 substrate 1; gene trap IST14520D7, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(IST14641C6)Tigm> | MGI:5247794
 
Name: AKT1 substrate 1; gene trap IST14641C6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(IST14913E5)Tigm> | MGI:5266595
 
Name: AKT1 substrate 1; gene trap IST14913E5, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Allele
Akt1s1<Gt(IST14943D12)Tigm> | MGI:5271726
 
Name: AKT1 substrate 1; gene trap IST14943D12, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Strain
MGI:5769984 | B6(Cg)-Akt1s1<tm1.1Rrth>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:6428144 | C57BL/6JSmoc-Akt1S1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6766952 | C57BL/6JGpt-Akt1s1<em1Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Genotype
Genotype
Symbol: Akt1s1/Akt1s1
Background: B6(Cg)-Akt1s1
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:7623295 | C57BL/6JSmoc-Akt1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Akt1<em2Smoc> | MGI:7288216
Name: thymoma viral proto-oncogene 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
16780593 | -
 
First Author: Nacusi LP
Year: 2006
Journal: Cell Div
Title: Akt1 sequentially phosphorylates p27kip1 within a conserved but non-canonical region.
Volume: 1
Pages: 11
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GO Term
GO:0032996 | Bcl3-Bcl10 complex
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Strain
MGI:6428143 | C57BL/6J-Akt1<em2Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
21266573 | J:170949
First Author: Caccamo A
Year: 2011
Journal: J Biol Chem
Title: Naturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanism.
Volume: 286
Issue: 11
Pages: 8924-32
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Publication
18570920 | -
First Author: Kang ES
Year: 2008
Journal: Exp Cell Res
Title: O-GlcNAc modulation at Akt1 Ser473 correlates with apoptosis of murine pancreatic beta cells.
Volume: 314
Issue: 11-12
Pages: 2238-48
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Publication
24628780 | -
 
First Author: Schmidt JW
Year: 2014
Journal: BMC Cancer
Title: Novel transcripts from a distinct promoter that encode the full-length AKT1 in human breast cancer cells.
Volume: 14
Pages: 195
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Publication
9218788 | -
First Author: Daram P
Year: 1997
Journal: EMBO J
Title: Tetramerization of the AKT1 plant potassium channel involves its C-terminal cytoplasmic domain.
Volume: 16
Issue: 12
Pages: 3455-63
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Protein Coding Gene
MGI:893587 | Dok1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P97465
Organism: Mus musculus/domesticus
Length: 482  
Fragment?: false
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Publication
23727834 | -
First Author: Cardenas-Rodriguez M
Year: 2013
Journal: Hum Mol Genet
Title: The Bardet-Biedl syndrome-related protein CCDC28B modulates mTORC2 function and interacts with SIN1 to control cilia length independently of the mTOR complex.
Volume: 22
Issue: 20
Pages: 4031-42
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Protein
Q8CEG5
Organism: Mus musculus/domesticus
Length: 200  
Fragment?: false
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Protein
Q8CEI3
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: false
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Protein
G3UX80
Organism: Mus musculus/domesticus
Length: 130  
Fragment?: false
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Protein
G3UZ16
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: false
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Protein
E9Q567
Organism: Mus musculus/domesticus
Length: 149  
Fragment?: false
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Protein
Q8C8I4
Organism: Mus musculus/domesticus
Length: 124  
Fragment?: true
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Protein
G3UXW3
Organism: Mus musculus/domesticus
Length: 68  
Fragment?: true
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Protein
A2AE01
Organism: Mus musculus/domesticus
Length: 104  
Fragment?: true
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Protein
Q3UFK1
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: false
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Protein
Q9D1N8
Organism: Mus musculus/domesticus
Length: 205  
Fragment?: false
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Protein Domain
IPR025271 | CCDC28
Type: Family
Description: This entry includes CCDC28A and CCDC28B. CCDC28B modulates mTORC2 complex assembly and function, possibly enhances AKT1 phosphorylation [].
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Allele
Tg(Lck-Akt1)1Pnt | MGI:3803799
Name: transgene insertion 1, Philip N Tsichlis
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
27349859 | J:238146
First Author: Rho O
Year: 2016
Journal: J Invest Dermatol
Title: Overexpression of PRAS40(T246A) in the Proliferative Compartment Suppresses mTORC1 Signaling, Keratinocyte Migration, and Skin Tumor Development.
Volume: 136
Issue: 10
Pages: 2070-2079
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Allele
Tg(tetO-Akt1*)K8Lbjn | MGI:4437713
Name: transgene insertion K8, Laura E Benjamin
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
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HT Experiment
GSE77862 | RNA-seq data from livers of 6 month old Akt1F/F;Akt2-/- versus Akt1F/F;Akt2-/-;Alb-Cre mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
20068142 | J:164333
First Author: Chakrabarti P
Year: 2010
Journal: Diabetes
Title: Mammalian target of rapamycin complex 1 suppresses lipolysis, stimulates lipogenesis, and promotes fat storage.
Volume: 59
Issue: 4
Pages: 775-81
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Allele
Tg(Myh6-Akt1*T308D*S473D)1Siz | MGI:3639116
Name: transgene insertion 1, Seigo Izumo
Allele Type: Transgenic
Attribute String: Constitutively active, Inserted expressed sequence
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Allele
Tg(Myh6-Akt1)564Anr | MGI:3639127
Name: transgene insertion 564, Anthony Rosenzweig
Allele Type: Transgenic
Attribute String: Constitutively active, Inserted expressed sequence
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Allele
Tg(Myh6-Akt1)20Anr | MGI:3639137
Name: transgene insertion 20, Anthony Rosenzweig
Allele Type: Transgenic
Attribute String: Constitutively active, Inserted expressed sequence
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Allele
Tg(MMTV-Akt1*T308D*S473D)7Mul | MGI:3794053
Name: transgene insertion 7, William J Muller
Allele Type: Transgenic
Attribute String: Constitutively active, Inserted expressed sequence
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Allele
Tg(Lck-Akt1*E40K)E-3Pnt | MGI:3803797
Name: transgene insertion E-3, Philip N Tsichlis
Allele Type: Transgenic
Attribute String: Constitutively active, Inserted expressed sequence
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Strain
MGI:6502047 | STOCK Tg(tetO-Akt1*)K8Lbjn/J
Attribute String: mutant stock, transgenic
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Allele
Tg(Ins1-Akt*)138Perm | MGI:5318861
Name: transgene insertion 138, M Permutt
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Ins2-Akt1*)3Mbb | MGI:5829193
Name: transgene insertion 3, Morris J Birnbaum
Allele Type: Transgenic
Attribute String: Constitutively active, Inserted expressed sequence
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Allele
Gt(ROSA)26Sor<tm4(Akt1*E17K)Jrld> | MGI:7547005
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 4, Jurgen Ruland
Allele Type: Targeted
Attribute String: Conditional ready, Constitutively active, Epitope tag, Inserted expressed sequence
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Protein Coding Gene
MGI:1916960 | Arap1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q4LDD4
Organism: Mus musculus/domesticus
Length: 1452  
Fragment?: false
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Publication
22844460 | J:189579
First Author: Wang H
Year: 2012
Journal: PLoS One
Title: Doxycycline regulated induction of AKT in murine prostate drives proliferation independently of p27 cyclin dependent kinase inhibitor downregulation.
Volume: 7
Issue: 7
Pages: e41330
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Publication
11500563 | -
First Author: Mäser P
Year: 2001
Journal: Plant Physiol
Title: Phylogenetic relationships within cation transporter families of Arabidopsis.
Volume: 126
Issue: 4
Pages: 1646-67
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Publication
11598222 | -
First Author: Kwak JM
Year: 2001
Journal: Plant Physiol
Title: Dominant negative guard cell K+ channel mutants reduce inward-rectifying K+ currents and light-induced stomatal opening in arabidopsis.
Volume: 127
Issue: 2
Pages: 473-85
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Publication
11825875 | -
First Author: Mouline K
Year: 2002
Journal: Genes Dev
Title: Pollen tube development and competitive ability are impaired by disruption of a Shaker K(+) channel in Arabidopsis.
Volume: 16
Issue: 3
Pages: 339-50
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Publication
26829980 | -
First Author: Wang XP
Year: 2016
Journal: Plant Physiol
Title: AtKC1 and CIPK23 Synergistically Modulate AKT1-Mediated Low-Potassium Stress Responses in Arabidopsis.
Volume: 170
Issue: 4
Pages: 2264-77
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Publication
25096783 | -
First Author: Li J
Year: 2014
Journal: Plant Cell
Title: The Os-AKT1 channel is critical for K+ uptake in rice roots and is modulated by the rice CBL1-CIPK23 complex.
Volume: 26
Issue: 8
Pages: 3387-402
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Publication
9741629 | -
First Author: Gaymard F
Year: 1998
Journal: Cell
Title: Identification and disruption of a plant shaker-like outward channel involved in K+ release into the xylem sap.
Volume: 94
Issue: 5
Pages: 647-55
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Publication
12671068 | -
First Author: Hosy E
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: The Arabidopsis outward K+ channel GORK is involved in regulation of stomatal movements and plant transpiration.
Volume: 100
Issue: 9
Pages: 5549-54
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Protein Domain
IPR045319 | KAT/AKT
Type: Family
Description: Potassium (K+) is an essential nutrient for plant growth and development. This entry represents a group of potassium channel proteins from plants, including KAT1-3, SKOR, GORK and AKT1/2/5/6 from Arabidopsis []. Together with AtHAK5, AKT1 mediates high-affinity K+ uptake into roots during seedling establishment and post-germination growth []. KAT1 is required for guard cell K+ uptake during light-induced stomatal opening []. AKT6, also known as SPIK, plays a role in K+ uptake in the growing pollen tube []. AKT1 has been shown to be regulated by the CBL1-CIPK23 complex [, ]. SKOR and GORK are both outward-rectifying potassium channels [, ].
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Allele
Tg(Lck-Akt1*)M-1Pnt | MGI:3803798
Name: transgene insertion M-1, Philip N Tsichlis
Allele Type: Transgenic
Attribute String: Constitutively active, Inserted expressed sequence
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Allele
Tg(CAG-lacZ,-Akt1*,-EGFP)56Ebm | MGI:3811006
Name: transgene insertion 56, Ernesto Bernal-Mizrachi
Allele Type: Transgenic
Attribute String: Conditional ready, Constitutively active, Inserted expressed sequence, Reporter
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Publication
11733558 | J:73141
First Author: Bernal-Mizrachi E
Year: 2001
Journal: J Clin Invest
Title: Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia.
Volume: 108
Issue: 11
Pages: 1631-8
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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