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Search results 2401 to 2498 out of 2498 for Arpp21

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Type Details Score
Publication
35106851 | J:349998
First Author: Lee J
Year: 2022
Journal: Glia
Title: Longitudinal intravital imaging of cerebral microinfarction reveals a dynamic astrocyte reaction leading to glial scar formation.
Volume: 70
Issue: 5
Pages: 975-988
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Publication
24742670 | J:215945
First Author: Sullivan SE
Year: 2014
Journal: J Biol Chem
Title: Mint proteins are required for synaptic activity-dependent amyloid precursor protein (APP) trafficking and amyloid ? generation.
Volume: 289
Issue: 22
Pages: 15374-83
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Publication
41295893 | J:379851
First Author: Aguado C
Year: 2026
Journal: J Alzheimers Dis
Title: Disruption of Ca(V)2.3 channels in the brain of the 5xFAD mice.
Volume: 109
Issue: 2
Pages: 699-717
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Genotype
Genotype
Symbol: Apmap/Apmap Tg(APPswe,PSEN1dE9)85Dbo/?
Background: involves: C57BL/6J * C57BL/6N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tafa5/Tafa5<+> Tg(APPswe,PSEN1dE9)85Dbo/?
Background: B6.Cg-Tg(APPswe,PSEN1dE9)85Dbo Tafa5
Zygosity: cx
Has Mutant Allele: true
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Publication
29295920 | J:348411
First Author: Han KH
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Migration-based selections of antibodies that convert bone marrow into trafficking microglia-like cells that reduce brain amyloid ?.
Volume: 115
Issue: 3
Pages: E372-E381
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Publication
35915180 | J:335653
First Author: Liu CC
Year: 2022
Journal: Nat Neurosci
Title: Peripheral apoE4 enhances Alzheimer's pathology and impairs cognition by compromising cerebrovascular function.
Volume: 25
Issue: 8
Pages: 1020-1033
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Publication
31878951 | J:341565
First Author: Pandey RS
Year: 2019
Journal: Mol Neurodegener
Title: Genetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer's disease.
Volume: 14
Issue: 1
Pages: 50
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Publication
25331900 | J:216662
First Author: Chow HM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: CDK5 activator protein p25 preferentially binds and activates GSK3?.
Volume: 111
Issue: 45
Pages: E4887-95
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Publication
26758846 | J:228864
First Author: Lian H
Year: 2016
Journal: J Neurosci
Title: Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease.
Volume: 36
Issue: 2
Pages: 577-89
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Publication
33846335 | J:311263
First Author: Kim K
Year: 2021
Journal: Nat Commun
Title: Therapeutic B-cell depletion reverses progression of Alzheimer's disease.
Volume: 12
Issue: 1
Pages: 2185
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Publication
25002035 | J:218071
First Author: Orre M
Year: 2014
Journal: Neurobiol Aging
Title: Isolation of glia from Alzheimer's mice reveals inflammation and?dysfunction.
Volume: 35
Issue: 12
Pages: 2746-2760
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Publication
35787714 | J:368199
First Author: Karaahmet B
Year: 2022
Journal: J Neuroinflammation
Title: Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathology.
Volume: 19
Issue: 1
Pages: 173
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Publication
30742114 | J:277544
First Author: Fang EF
Year: 2019
Journal: Nat Neurosci
Title: Mitophagy inhibits amyloid-? and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
Volume: 22
Issue: 3
Pages: 401-412
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Publication
42180652 | J:388165
 
First Author: Sauv?? F
Year: 2026
Journal: Cell Press Blue
Title: Tanycytic degeneration impairs tau clearance and contributes to Alzheimer's disease pathology.
Volume: 1
Issue: 1
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Publication
21980472 | J:368227
First Author: Tran HT
Year: 2011
Journal: PLoS One
Title: Distinct temporal and anatomical distributions of amyloid-? and tau abnormalities following controlled cortical impact in transgenic mice.
Volume: 6
Issue: 9
Pages: e25475
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Publication
33922642 | J:386849
 
First Author: Delgado-Peraza F
Year: 2021
Journal: Cells
Title: Neuronal and Astrocytic Extracellular Vesicle Biomarkers in Blood Reflect Brain Pathology in Mouse Models of Alzheimer's Disease.
Volume: 10
Issue: 5
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Publication
28683325 | J:254503
First Author: Haas LT
Year: 2017
Journal: Cell Rep
Title: Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer's Mouse Phenotypes.
Volume: 20
Issue: 1
Pages: 76-88
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Publication
35236988 | J:338102
First Author: Xiong J
Year: 2022
Journal: Nature
Title: FSH blockade improves cognition in mice with Alzheimer's disease.
Volume: 603
Issue: 7901
Pages: 470-476
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Publication
38476461 | J:346241
 
First Author: Devadoss D
Year: 2024
Journal: Front Mol Neurosci
Title: LRRC25 expression during physiological aging and in mouse models of Alzheimer's disease and iPSC-derived neurons.
Volume: 17
Pages: 1365752
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Publication
30867420 | J:273276
First Author: He Y
Year: 2019
Journal: Nat Commun
Title: Amyloid ? oligomers suppress excitatory transmitter release via presynaptic depletion of phosphatidylinositol-4,5-bisphosphate.
Volume: 10
Issue: 1
Pages: 1193
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Publication
27210751 | J:235961
First Author: Hamilton A
Year: 2016
Journal: Cell Rep
Title: Chronic Pharmacological mGluR5 Inhibition Prevents Cognitive Impairment and Reduces Pathogenesis in an Alzheimer Disease Mouse Model.
Volume: 15
Issue: 9
Pages: 1859-65
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Publication
24684630 | J:214689
First Author: Kuwabara Y
Year: 2014
Journal: J Neurochem
Title: Impairments of long-term depression induction and motor coordination precede A? accumulation in the cerebellum of APPswe/PS1dE9 double transgenic mice.
Volume: 130
Issue: 3
Pages: 432-43
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Publication
29113959 | J:260831
 
First Author: Lardenoije R
Year: 2018
Journal: Mol Cell Neurosci
Title: Age-related epigenetic changes in hippocampal subregions of four animal models of Alzheimer's disease.
Volume: 86
Pages: 1-15
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Publication
33663578 | J:311283
First Author: Chen M
Year: 2021
Journal: Mol Neurodegener
Title: Enhancing GABAergic signaling ameliorates aberrant gamma oscillations of olfactory bulb in AD mouse models.
Volume: 16
Issue: 1
Pages: 14
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Publication
41061696 | J:377422
First Author: Mao Y
Year: 2026
Journal: Cell Metab
Title: AMPK?2 signals amino acid insufficiency to inhibit protein synthesis.
Volume: 38
Issue: 1
Pages: 192-207.e8
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Publication
38502413 | J:350687
First Author: Kong Y
Year: 2024
Journal: Mol Neurobiol
Title: Relationship Between Reactive Astrocytes, by [(18)F]SMBT-1 Imaging, with Amyloid-Beta, Tau, Glucose Metabolism, and TSPO in Mouse Models of Alzheimer's Disease.
Volume: 61
Issue: 10
Pages: 8387-8401
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Publication
33955647 | J:311343
First Author: Wu L
Year: 2021
Journal: Aging Cell
Title: Therapeutic efficacy of novel memantine nitrate MN-08 in animal models of Alzheimer's disease.
Volume: 20
Issue: 6
Pages: e13371
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Publication
27752775 | J:311368
First Author: Jan A
Year: 2017
Journal: Acta Neuropathol
Title: eEF2K inhibition blocks A?42 neurotoxicity by promoting an NRF2 antioxidant response.
Volume: 133
Issue: 1
Pages: 101-119
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Publication
40373772 | J:369611
First Author: Liu J
Year: 2025
Journal: Immunity
Title: Microglial TMEM119 binds to amyloid-? to promote its clearance in an A?-depositing mouse model of Alzheimer's disease.
Volume: 58
Issue: 7
Pages: 1830-1846.e7
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Publication
22912745 | J:189978
First Author: Kamphuis W
Year: 2012
Journal: PLoS One
Title: GFAP isoforms in adult mouse brain with a focus on neurogenic astrocytes and reactive astrogliosis in mouse models of Alzheimer disease.
Volume: 7
Issue: 8
Pages: e42823
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Publication
26280122 | J:228804
First Author: Ceglia I
Year: 2015
Journal: Nat Med
Title: APP intracellular domain-WAVE1 pathway reduces amyloid-? production.
Volume: 21
Issue: 9
Pages: 1054-9
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Publication
32849642 | J:319606
 
First Author: Zhao J
Year: 2020
Journal: Front Immunol
Title: Administration of Amyloid Precursor Protein Gene Deleted Mouse ESC-Derived Thymic Epithelial Progenitors Attenuates Alzheimer's Pathology.
Volume: 11
Pages: 1781
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Publication
41488470 | J:385505
First Author: Cho Y
Year: 2026
Journal: MedComm (2020)
Title: Ramalin Ameliorates Alzheimer's Disease Pathology by Targeting BACE1, HDAC6, and MAPK Pathways.
Volume: 7
Issue: 1
Pages: e70518
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Publication
23432034 | J:199628
First Author: Chakravarthy B
Year: 2013
Journal: J Neurochem
Title: A synthetic peptide corresponding to a region of the human pericentriolar material 1 (PCM-1) protein binds ?-amyloid (A?1-42 ) oligomers.
Volume: 126
Issue: 3
Pages: 415-24
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Publication
27425620 | J:238659
First Author: Liebmann T
Year: 2016
Journal: Cell Rep
Title: Three-Dimensional Study of Alzheimer's Disease Hallmarks Using the iDISCO Clearing Method.
Volume: 16
Issue: 4
Pages: 1138-1152
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Publication
25617315 | J:232678
First Author: Clarke JR
Year: 2015
Journal: EMBO Mol Med
Title: Alzheimer-associated A? oligomers impact the central nervous system to induce peripheral metabolic deregulation.
Volume: 7
Issue: 2
Pages: 190-210
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Publication
23534431 | J:352629
First Author: Stargardt A
Year: 2013
Journal: Aging Cell
Title: Reduced amyloid-? degradation in early Alzheimer's disease but not in the APPswePS1dE9 and 3xTg-AD mouse models.
Volume: 12
Issue: 3
Pages: 499-507
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Publication
35961653 | J:352637
First Author: Israel LL
Year: 2022
Journal: ACS Nano
Title: Signature Effects of Vector-Guided Systemic Nano Bioconjugate Delivery Across Blood-Brain Barrier of Normal, Alzheimer's, and Tumor Mouse Models.
Volume: 16
Issue: 8
Pages: 11815-11832
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Publication
33791294 | J:318609
 
First Author: Huang X
Year: 2021
Journal: Front Cell Dev Biol
Title: Tetramethylpyrazine Improves Cognitive Impairment and Modifies the Hippocampal Proteome in Two Mouse Models of Alzheimer's Disease.
Volume: 9
Pages: 632843
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Publication
33672482 | J:352640
 
First Author: Drews HJ
Year: 2021
Journal: Pharmaceuticals (Basel)
Title: Losartan Improves Memory, Neurogenesis and Cell Motility in Transgenic Alzheimer's Mice.
Volume: 14
Issue: 2
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Publication
35775150 | J:349319
First Author: Vande Vyver M
Year: 2022
Journal: Epilepsia
Title: Higher susceptibility to 6?Hz corneal kindling and lower responsiveness to antiseizure drugs in mouse models of Alzheimer's disease.
Volume: 63
Issue: 10
Pages: 2703-2715
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Publication
26982728 | J:232713
First Author: Roy DS
Year: 2016
Journal: Nature
Title: Memory retrieval by activating engram cells in mouse models of early Alzheimer's disease.
Volume: 531
Issue: 7595
Pages: 508-12
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Publication
31737743 | J:352853
First Author: Wang S
Year: 2019
Journal: Neurophotonics
Title: Label-free multiphoton imaging of ?-amyloid plaques in Alzheimer's disease mouse models.
Volume: 6
Issue: 4
Pages: 045008
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Publication
29211722 | J:274288
First Author: Sorrentino V
Year: 2017
Journal: Nature
Title: Enhancing mitochondrial proteostasis reduces amyloid-? proteotoxicity.
Volume: 552
Issue: 7684
Pages: 187-193
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Publication
33863723 | J:358337
 
First Author: Chen G
Year: 2021
Journal: Sci Adv
Title: Netrin-1 receptor UNC5C cleavage by active ?-secretase enhances neurodegeneration, promoting Alzheimer's disease pathologies.
Volume: 7
Issue: 16
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Publication
37358017 | J:339350
First Author: Marinho D
Year: 2023
Journal: Aging Cell
Title: Reduction of class I histone deacetylases ameliorates ER-mitochondria cross-talk in Alzheimer's disease.
Volume: 22
Issue: 8
Pages: e13895
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Publication
32404941 | J:348427
First Author: Song G
Year: 2020
Journal: Sci Rep
Title: Multimodal Coherent Imaging of Retinal Biomarkers of Alzheimer's Disease in a Mouse Model.
Volume: 10
Issue: 1
Pages: 7912
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Publication
41480410 | J:385742
First Author: Tang S
Year: 2026
Journal: Genes Dis
Title: Hippocampus-targeted BDNF gene therapy to rescue cognitive impairments of Alzheimer's disease in multiple mouse models.
Volume: 13
Issue: 2
Pages: 101649
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Publication
35339896 | J:322782
 
First Author: Zhou Q
Year: 2022
Journal: EBioMedicine
Title: Human tau accumulation promotes glycogen synthase kinase-3? acetylation and thus upregulates the kinase: A vicious cycle in Alzheimer neurodegeneration.
Volume: 78
Pages: 103970
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Publication
25673868 | J:219873
First Author: Ben Haim L
Year: 2015
Journal: J Neurosci
Title: The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer's and Huntington's diseases.
Volume: 35
Issue: 6
Pages: 2817-29
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Publication
30322407 | J:368485
First Author: Ceyz?riat K
Year: 2018
Journal: Acta Neuropathol Commun
Title: Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer's disease.
Volume: 6
Issue: 1
Pages: 104
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Publication
34099706 | J:322192
First Author: Fitz NF
Year: 2021
Journal: Nat Commun
Title: Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer's disease.
Volume: 12
Issue: 1
Pages: 3416
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Publication
39904338 | J:365465
First Author: McManus RM
Year: 2025
Journal: Immunity
Title: NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression.
Volume: 58
Issue: 2
Pages: 326-343.e11
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Publication
30506549 | J:327646
First Author: De Rossi P
Year: 2019
Journal: Brain Pathol
Title: Aberrant accrual of BIN1 near Alzheimer's disease amyloid deposits in transgenic models.
Volume: 29
Issue: 4
Pages: 485-501
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Publication
25622143 | J:274055
First Author: Orr AG
Year: 2015
Journal: Nat Neurosci
Title: Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory.
Volume: 18
Issue: 3
Pages: 423-34
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Publication
28591834 | J:277756
First Author: Lu NN
Year: 2018
Journal: Cereb Cortex
Title: Cholinergic Grb2-Associated-Binding Protein 1 Regulates Cognitive Function.
Volume: 28
Issue: 7
Pages: 2391-2404
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Publication
17556372 | J:124804
First Author: Jankowsky JL
Year: 2007
Journal: J Biol Chem
Title: Rodent A beta modulates the solubility and distribution of amyloid deposits in transgenic mice.
Volume: 282
Issue: 31
Pages: 22707-20
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Publication
27569580 | J:258151
 
First Author: Melnikova T
Year: 2016
Journal: Neurobiol Dis
Title: Sex-related dimorphism in dentate gyrus atrophy and behavioral phenotypes in an inducible tTa:APPsi transgenic model of Alzheimer's disease.
Volume: 96
Pages: 171-185
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Publication
41916281 | J:384241
     
First Author: Ellingford R
Year: 2026
Journal: Neuron
Title: Alzheimer's disease pathology degrades an NMDA receptor-dependent spontaneous activity pattern in cortico-hippocampal circuits.
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Publication
25878292 | J:221673
First Author: Hall AM
Year: 2015
Journal: J Neurosci
Title: Tau-dependent Kv4.2 depletion and dendritic hyperexcitability in a mouse model of Alzheimer's disease.
Volume: 35
Issue: 15
Pages: 6221-30
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Publication
40435260 | J:367447
First Author: Sanchez-Garcia MA
Year: 2025
Journal: Sci Adv
Title: Inactivation of the PHD3-FOXO3 axis blunts the type I interferon response in microglia and ameliorates Alzheimer's disease progression.
Volume: 11
Issue: 22
Pages: eadu2244
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Publication
18753367 | J:138796
First Author: Matsuda S
Year: 2008
Journal: J Neurosci
Title: BRI2 inhibits amyloid beta-peptide precursor protein processing by interfering with the docking of secretases to the substrate.
Volume: 28
Issue: 35
Pages: 8668-76
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Publication
37973869 | J:348885
First Author: Zielinski M
Year: 2023
Journal: Nat Neurosci
Title: Cryo-EM of A? fibrils from mouse models find tg-APP(ArcSwe) fibrils resemble those found in patients with sporadic Alzheimer's disease.
Volume: 26
Issue: 12
Pages: 2073-2080
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Publication
40495448 | J:369898
First Author: Peralta Reyes FS
Year: 2025
Journal: Neuropathol Appl Neurobiol
Title: Lecanemab Binds to Transgenic Mouse Model-Derived Amyloid-? Fibril Structures Resembling Alzheimer's Disease Type I, Type II and Arctic Folds.
Volume: 51
Issue: 3
Pages: e70022
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Publication
30414727 | J:272048
 
First Author: Midani-Kur?ak JS
Year: 2019
Journal: Brain Res
Title: Effect of tau-pathology on charged multivesicular body protein 2b (CHMP2B).
Volume: 1706
Pages: 224-236
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Publication
16753269 | J:111748
First Author: Melnikova T
Year: 2006
Journal: Neuroscience
Title: Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer's disease in a sex-dimorphic pattern.
Volume: 141
Issue: 3
Pages: 1149-62
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Publication
34102111 | J:325335
First Author: Chen JF
Year: 2021
Journal: Neuron
Title: Enhancing myelin renewal reverses cognitive dysfunction in a murine model of Alzheimer's disease.
Volume: 109
Issue: 14
Pages: 2292-2307.e5
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Publication
29186695 | J:255230
First Author: Savas JN
Year: 2017
Journal: Cell Rep
Title: Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology.
Volume: 21
Issue: 9
Pages: 2614-2627
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Publication
39087029 | J:358640
 
First Author: Antila S
Year: 2024
Journal: Nat Cardiovasc Res
Title: Sustained meningeal lymphatic vessel atrophy or expansion does not alter Alzheimer's disease-related amyloid pathology.
Volume: 3
Pages: 474-491
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Publication
23839581 | J:353499
First Author: Pooler AM
Year: 2013
Journal: J Comp Neurol
Title: Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology.
Volume: 521
Issue: 18
Pages: 4236-48
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Publication
41419665 | J:386200
First Author: He A
Year: 2026
Journal: Nat Aging
Title: Allosteric activation of a cell-type-specific GPR120 inhibits amyloid pathology of Alzheimer's disease.
Volume: 6
Issue: 1
Pages: 181-199
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Publication
32392471 | J:301449
First Author: Sauerbeck AD
Year: 2020
Journal: Neuron
Title: SEQUIN Multiscale Imaging of Mammalian Central Synapses Reveals Loss of Synaptic Connectivity Resulting from Diffuse Traumatic Brain Injury.
Volume: 107
Issue: 2
Pages: 257-273.e5
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Publication
39994425 | J:373293
First Author: Liang Z
Year: 2025
Journal: Mol Psychiatry
Title: Dual recombinase-mediated intersectional genetics defines the functional heterogeneity of neural stem cells in adult hippocampus.
Volume: 30
Issue: 8
Pages: 3516-3532
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Publication
36736651 | J:353713
 
First Author: Wu SL
Year: 2023
Journal: Exp Neurol
Title: Brain region-specific myelinogenesis is not directly linked to amyloid-? in APP/PS1 transgenic mice.
Volume: 362
Pages: 114344
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Publication
34480901 | J:310638
First Author: Nies SH
Year: 2021
Journal: J Biol Chem
Title: Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-?.
Volume: 297
Issue: 4
Pages: 101159
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Publication
27022623 | J:240236
 
First Author: Shen X
Year: 2016
Journal: eNeuro
Title: Neurons in Vulnerable Regions of the Alzheimer's Disease Brain Display Reduced ATM Signaling.
Volume: 3
Issue: 1
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Publication
38776461 | J:360710
First Author: Kong Y
Year: 2024
Journal: ACS Chem Neurosci
Title: Increased Cerebral Level of P2X7R in a Tauopathy Mouse Model by PET Using [(18)F]GSK1482160.
Volume: 15
Issue: 11
Pages: 2112-2120
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Publication
40604342 | J:369197
First Author: Akkaoui J
Year: 2025
Journal: J Cell Mol Med
Title: Robust Increase in IQCK Protein Expression in Mouse Models of Alzheimer's Disease and iPSC-Derived Neurons.
Volume: 29
Issue: 13
Pages: e70686
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Publication
24305500 | J:286212
First Author: Reinert J
Year: 2014
Journal: J Alzheimers Dis
Title: A?38 in the brains of patients with sporadic and familial Alzheimer's disease and transgenic mouse models.
Volume: 39
Issue: 4
Pages: 871-81
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Publication
31213067 | J:277676
 
First Author: Findley CA
Year: 2019
Journal: ASN Neuro
Title: Amyloid Beta-Related Alterations to Glutamate Signaling Dynamics During Alzheimer's Disease Progression.
Volume: 11
Pages: 1759091419855541
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Publication
32727580 | J:311717
First Author: Kumar S
Year: 2020
Journal: Acta Neuropathol Commun
Title: Phosphorylated A? peptides in human Down syndrome brain and different Alzheimer's-like mouse models.
Volume: 8
Issue: 1
Pages: 118
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Publication
28694463 | J:249724
First Author: Dudeffant C
Year: 2017
Journal: Sci Rep
Title: Contrast-enhanced MR microscopy of amyloid plaques in five mouse models of amyloidosis and in human Alzheimer's disease brains.
Volume: 7
Issue: 1
Pages: 4955
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Publication
37463212 | J:344394
First Author: Cazzaro S
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Slingshot homolog-1-mediated Nrf2 sequestration tips the balance from neuroprotection to neurodegeneration in Alzheimer's disease.
Volume: 120
Issue: 30
Pages: e2217128120
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