| Type |
Details |
Score |
| Publication |
| First Author: |
Dong F |
| Year: |
2023 |
| Journal: |
FASEB J |
| Title: |
Complex chemical signals dictate Ah receptor activation through the gut-lung axis. |
| Volume: |
37 |
| Issue: |
7 |
| Pages: |
e23010 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Noda K |
| Year: |
2023 |
| Journal: |
J Biol Chem |
| Title: |
Characterization of Rab32- and Rab38-positive lysosome-related organelles in osteoclasts and macrophages. |
| Volume: |
299 |
| Issue: |
10 |
| Pages: |
105191 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mencarelli C |
| Year: |
2012 |
| Journal: |
J Biol Chem |
| Title: |
Goodpasture antigen-binding protein/ceramide transporter binds to human serum amyloid P-component and is present in brain amyloid plaques. |
| Volume: |
287 |
| Issue: |
18 |
| Pages: |
14897-911 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Low MJ |
| Year: |
2001 |
| Journal: |
J Clin Invest |
| Title: |
Somatostatin is required for masculinization of growth hormone-regulated hepatic gene expression but not of somatic growth. |
| Volume: |
107 |
| Issue: |
12 |
| Pages: |
1571-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Córdoba-Chacón J |
| Year: |
2011 |
| Journal: |
Am J Physiol Endocrinol Metab |
| Title: |
Somatostatin and its receptors contribute in a tissue-specific manner to the sex-dependent metabolic (fed/fasting) control of growth hormone axis in mice. |
| Volume: |
300 |
| Issue: |
1 |
| Pages: |
E46-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Briliūtė J |
| Year: |
2019 |
| Journal: |
Nat Microbiol |
| Title: |
Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. |
| Volume: |
4 |
| Issue: |
9 |
| Pages: |
1571-1581 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
This entry represents a family of glycosyl hydrolases (GH) from CAZy family 18 that are mainly found in Bacteroidetes, including the endoglycosidase BT1044 from Bacteroides thetaiotaomicron (). This protein folds into the canonical (β/α)8 barrel (TIM barrel) fold common to many GH structures, with the N-terminal a discrete extended structure that would orientate the lipoprotein on the cell surface with the active site facing the extracellular environment []. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Weng T |
| Year: |
2010 |
| Journal: |
J Cell Sci |
| Title: |
Osteoblastic molecular scaffold Gab1 is required for maintaining bone homeostasis. |
| Volume: |
123 |
| Issue: |
Pt 5 |
| Pages: |
682-9 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, transgenic |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, transgenic |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Louridas M |
| Year: |
2009 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Galanin is highly expressed in bone marrow mesenchymal stem cells and facilitates migration of cells both in vitro and in vivo. |
| Volume: |
390 |
| Issue: |
3 |
| Pages: |
867-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lyubetska H |
| Year: |
2015 |
| Journal: |
Neuroscience |
| Title: |
An elevated level of circulating galanin promotes developmental expression of myelin basic protein in the mouse brain. |
| Volume: |
284 |
|
| Pages: |
581-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang L |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
Galanin transgenic mice with elevated circulating galanin levels alleviate demyelination in a cuprizone-induced MS mouse model. |
| Volume: |
7 |
| Issue: |
3 |
| Pages: |
e33901 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Poritsanos NJ |
| Year: |
2009 |
| Journal: |
Int J Obes (Lond) |
| Title: |
Chronic increase of circulating galanin levels induces obesity and marked alterations in lipid metabolism similar to metabolic syndrome. |
| Volume: |
33 |
| Issue: |
12 |
| Pages: |
1381-9 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
transgenic, mutant strain, coisogenic |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schiffner S |
| Year: |
2014 |
| Journal: |
Exp Eye Res |
| Title: |
Tg(Grm1) transgenic mice: a murine model that mimics spontaneous uveal melanoma in humans? |
| Volume: |
127 |
|
| Pages: |
59-68 |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 1a, Gabriel E DiMattia |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 1b, Gabriel E DiMattia |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 2, Gabriel E DiMattia |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, targeted mutation |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shaw MA |
| Year: |
2016 |
| Journal: |
Blood |
| Title: |
Limiting prothrombin activation to meizothrombin is compatible with survival but significantly alters hemostasis in mice. |
| Volume: |
128 |
| Issue: |
5 |
| Pages: |
721-31 |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion, Gabriel E DiMattia |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sher LB |
| Year: |
2004 |
| Journal: |
Endocrinology |
| Title: |
Transgenic expression of 11beta-hydroxysteroid dehydrogenase type 2 in osteoblasts reveals an anabolic role for endogenous glucocorticoids in bone. |
| Volume: |
145 |
| Issue: |
2 |
| Pages: |
922-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Henneicke H |
| Year: |
2017 |
| Journal: |
Endocrinology |
| Title: |
Chronic Mild Stress Causes Bone Loss via an Osteoblast-Specific Glucocorticoid-Dependent Mechanism. |
| Volume: |
158 |
| Issue: |
6 |
| Pages: |
1939-1950 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kalak R |
| Year: |
2009 |
| Journal: |
Bone |
| Title: |
Endogenous glucocorticoid signalling in osteoblasts is necessary to maintain normal bone structure in mice. |
| Volume: |
45 |
| Issue: |
1 |
| Pages: |
61-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Henneicke H |
| Year: |
2011 |
| Journal: |
Bone |
| Title: |
Corticosterone selectively targets endo-cortical surfaces by an osteoblast-dependent mechanism. |
| Volume: |
49 |
| Issue: |
4 |
| Pages: |
733-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tu J |
| Year: |
2016 |
| Journal: |
Am J Pathol |
| Title: |
Transgenic Disruption of Glucocorticoid Signaling in Osteoblasts Attenuates Joint Inflammation in Collagen Antibody-Induced Arthritis. |
| Volume: |
186 |
| Issue: |
5 |
| Pages: |
1293-301 |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 2, Teresa K Woodruff |
| Allele Type: |
Transgenic |
| Attribute String: |
Dominant negative, Inserted expressed sequence |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
transgenic, mutant strain, coisogenic |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, transgenic |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Saegusa H |
| Year: |
2014 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
N-type voltage-dependent Ca2+ channel in non-excitable microglial cells in mice is involved in the pathophysiology of neuropathic pain. |
| Volume: |
450 |
| Issue: |
1 |
| Pages: |
142-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang X |
| Year: |
2019 |
| Journal: |
Sci Rep |
| Title: |
Blockade of microglial Cav1.2 Ca2+ channel exacerbates the symptoms in a Parkinson's disease model. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
9138 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huntula S |
| Year: |
2019 |
| Journal: |
Cell Calcium |
| Title: |
Involvement of N-type Ca2+ channel in microglial activation and its implications to aging-induced exaggerated cytokine response. |
| Volume: |
82 |
|
| Pages: |
102059 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jardine JG |
| Year: |
2015 |
| Journal: |
Science |
| Title: |
HIV-1 VACCINES. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen. |
| Volume: |
349 |
| Issue: |
6244 |
| Pages: |
156-61 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Briney B |
| Year: |
2016 |
| Journal: |
Cell |
| Title: |
Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies. |
| Volume: |
166 |
| Issue: |
6 |
| Pages: |
1459-1470.e11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Medina-RamÃrez M |
| Year: |
2017 |
| Journal: |
J Exp Med |
| Title: |
Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo. |
| Volume: |
214 |
| Issue: |
9 |
| Pages: |
2573-2590 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Parks KR |
| Year: |
2019 |
| Journal: |
Cell Rep |
| Title: |
Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization. |
| Volume: |
29 |
| Issue: |
10 |
| Pages: |
3060-3072.e7 |
|
•
•
•
•
•
|
| Allele |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 6, Mouse Clinical Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
growth hormone; mutation 1, Bruce Beutler |
| Allele Type: |
Chemically induced (ENU) |
| Attribute String: |
Not Specified |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, chemically induced mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 2/1, Jeffrey Robbins |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 432, Sally A Camper |
| Allele Type: |
Transgenic |
| Attribute String: |
Recombinase |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion m-0.7+4, Vincent M Christoffels |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
hypoxanthine phosphoribosyltransferase 1; targeted mutation 2, Vincent M Christoffels |
| Allele Type: |
Targeted |
| Attribute String: |
Humanized sequence, Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion r-0.25, Vincent M Christoffels |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, congenic, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, transgenic |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, transgenic |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
targeted mutation, mutant stock |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mona B |
| Year: |
2016 |
| Journal: |
Dev Biol |
| Title: |
Regulating the dorsal neural tube expression of Ptf1a through a distal 3' enhancer. |
| Volume: |
418 |
| Issue: |
1 |
| Pages: |
216-225 |
|
•
•
•
•
•
|
| Allele |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 15, Mouse Clinical Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 17, Mouse Clinical Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Inserted expressed sequence |
|
•
•
•
•
•
|
| Allele |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 12, Mouse Clinical Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Altered localization, Conditional ready, Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 13, Mouse Clinical Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 18, Mouse Clinical Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 5, Mouse Clinical Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Epitope tag, Inserted expressed sequence |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Mt1a-GPHB5)1Sok/? |
| Background: |
involves: C57BL/6 |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
F2/F2 |
| Background: |
B6.129P2-F2 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(MMTV-cre)#Tfln/? |
| Background: |
involves: 129S6/SvEvTac |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Dct-Grm1)ESzc/? |
| Background: |
involves: C57BL/6J |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Amh-SMAD2*)#Jebu/? |
| Background: |
FVB/N-Tg(Amh-SMAD2*)#Jebu |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Gh-Gal)4599Vron/Tg(Gh-Gal)4599Vron |
| Background: |
B6.Cg-Tg(Gh-Gal)4599Vron |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Gh-Gal)4599Vron/? |
| Background: |
involves: C57BL/6 * CD-1 * SJL |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Itgam-cre/ERT2,U6-RNAi:Cacna1b)17Ttan/? |
| Background: |
C57BL/6J-Tg(Itgam-cre/ERT2,U6-RNAi:Cacna1b)17Ttan |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Dct-Grm1)ESzc/? |
| Background: |
C57BL/6J-Tg(Dct-Grm1)ESzc |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gh/Gh |
| Background: |
C57BL/6J-Gh |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Olig2/Olig2<+> |
| Background: |
involves: 129 * C57BL/6 * FVB/N |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
54
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
86
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hine C |
| Year: |
2017 |
| Journal: |
Cell Metab |
| Title: |
Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production. |
| Volume: |
25 |
| Issue: |
6 |
| Pages: |
1320-1333.e5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Romero MI |
| Year: |
1997 |
| Journal: |
Neuroendocrinology |
| Title: |
Identification of growth hormone-releasing hormone and somatostatin neurons projecting to the median eminence in normal and growth hormone-deficient Ames dwarf mice. |
| Volume: |
65 |
| Issue: |
2 |
| Pages: |
107-16 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hsieh CC |
| Year: |
2002 |
| Journal: |
Mech Ageing Dev |
| Title: |
Implications for the insulin signaling pathway in Snell dwarf mouse longevity: a similarity with the C. elegans longevity paradigm. |
| Volume: |
123 |
| Issue: |
9 |
| Pages: |
1229-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li X |
| Year: |
2022 |
| Journal: |
Aging Cell |
| Title: |
Cap-independent translation of GPLD1 enhances markers of brain health in long-lived mutant and drug-treated mice. |
| Volume: |
21 |
| Issue: |
9 |
| Pages: |
e13685 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Montecino-Rodriguez E |
| Year: |
1996 |
| Journal: |
J Immunol |
| Title: |
Defective B cell development in Snell dwarf (dw/dw) mice can be corrected by thyroxine treatment. |
| Volume: |
157 |
| Issue: |
8 |
| Pages: |
3334-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gala RR |
| Year: |
1993 |
| Journal: |
Proc Soc Exp Biol Med |
| Title: |
Influence of prolactin and growth hormone on the activation of dwarf mouse lymphocytes in vivo. |
| Volume: |
204 |
| Issue: |
2 |
| Pages: |
224-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stout MB |
| Year: |
2014 |
| Journal: |
Aging (Albany NY) |
| Title: |
Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice. |
| Volume: |
6 |
| Issue: |
7 |
| Pages: |
575-86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
van Buul-Offers SC |
| Year: |
1994 |
| Journal: |
J Endocrinol |
| Title: |
Insulin-like growth factors-I and -II and their binding proteins during postnatal development of dwarf Snell mice before and during growth hormone and thyroxine therapy. |
| Volume: |
143 |
| Issue: |
1 |
| Pages: |
191-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Slabaugh MB |
| Year: |
1981 |
| Journal: |
Endocrinology |
| Title: |
Growth hormone and prolactin synthesis in normal and homozygous Snell and Ames dwarf mice. |
| Volume: |
109 |
| Issue: |
4 |
| Pages: |
1040-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Koedam JA |
| Year: |
1998 |
| Journal: |
J Endocrinol |
| Title: |
Insulin-like growth factor-binding protein-3 protease activity in Snell normal and Pit-1 deficient dwarf mice. |
| Volume: |
157 |
| Issue: |
2 |
| Pages: |
295-303 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cheng TC |
| Year: |
1983 |
| Journal: |
Endocrinology |
| Title: |
Etiology of growth hormone deficiency in little, Ames, and Snell dwarf mice. |
| Volume: |
113 |
| Issue: |
5 |
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