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Search results 2401 to 2500 out of 6467 for Myc

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Type Details Score
Allele
Mycbp<Gt(OST220957)Lex> | MGI:4238808
 
Name: MYC binding protein; gene trap OST220957, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Mycbp<Gt(OST359643)Lex> | MGI:4293557
 
Name: MYC binding protein; gene trap OST359643, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Mycbp<Gt(OST369921)Lex> | MGI:4296899
 
Name: MYC binding protein; gene trap OST369921, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Mycbp<Gt(OST404115)Lex> | MGI:4306838
 
Name: MYC binding protein; gene trap OST404115, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Mycbp<Gt(OST404116)Lex> | MGI:4306839
 
Name: MYC binding protein; gene trap OST404116, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Mycbp<Gt(AA0029)Wtsi> | MGI:4331030
 
Name: MYC binding protein; gene trap AA0029, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Myct1<Gt(b5p6c4)Rul> | MGI:4833075
 
Name: myc target 1; gene trap b5p6c4, H Earl Ruley
Allele Type: Gene trapped
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Allele
Mycbp<tm1e(KOMP)Wtsi> | MGI:4939712
Name: MYC binding protein; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Myct1<tm1a(EUCOMM)Wtsi> | MGI:5286392
Name: myc target 1; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Myct1<em1Choi> | MGI:6696430
Name: myc target 1; endonuclease-mediated mutation 1, Kyunghee Choi
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Myct1<tm1.1Cya> | MGI:6696431
Name: myc target 1; targeted mutation 1.1, Cyagen Biosciences
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Myct1<em2Cya> | MGI:7585196
Name: myc target 1; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Mycbp<em1(IMPC)Kmpc> | MGI:7761815
Name: MYC binding protein; endonuclease-mediated mutation 1, Korea Mouse Phenotyping Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
34085047 | J:309100
First Author: Arriaga JM
Year: 2020
Journal: Nat Cancer
Title: A MYC and RAS co-activation signature in localized prostate cancer drives bone metastasis and castration resistance.
Volume: 1
Issue: 11
Pages: 1082-1096
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Publication
28089889 | J:239378
First Author: Mollaoglu G
Year: 2017
Journal: Cancer Cell
Title: MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition.
Volume: 31
Issue: 2
Pages: 270-285
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Publication
10616903 | J:59100
First Author: Quéva C
Year: 1999
Journal: Cell Growth Differ
Title: Dwarfism and dysregulated proliferation in mice overexpressing the MYC antagonist MAD1.
Volume: 10
Issue: 12
Pages: 785-96
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Publication
15576399 | J:94513
First Author: Hu MC
Year: 2005
Journal: Development
Title: Smad1, beta-catenin and Tcf4 associate in a molecular complex with the Myc promoter in dysplastic renal tissue and cooperate to control Myc transcription.
Volume: 132
Issue: 1
Pages: 215-25
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Publication
15994934 | J:99526
First Author: Osthus RC
Year: 2005
Journal: Cancer Res
Title: The Myc target gene JPO1/CDCA7 is frequently overexpressed in human tumors and has limited transforming activity in vivo.
Volume: 65
Issue: 13
Pages: 5620-7
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Publication
22326754 | J:181991
First Author: Vincent-Fabert C
Year: 2012
Journal: Am J Pathol
Title: A defect of the INK4-Cdk4 checkpoint and Myc collaborate in blastoid mantle cell lymphoma-like lymphoma formation in mice.
Volume: 180
Issue: 4
Pages: 1688-701
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Publication
27589562 | J:314638
First Author: Jhan JR
Year: 2016
Journal: Oncotarget
Title: Stat3 accelerates Myc induced tumor formation while reducing growth rate in a mouse model of breast cancer.
Volume: 7
Issue: 40
Pages: 65797-65807
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Publication
35933014 | J:339504
First Author: Takada I
Year: 2022
Journal: J Biol Chem
Title: Transcriptional coregulator Ess2 controls survival of post-thymic CD4(+) T cells through the Myc and IL-7 signaling pathways.
Volume: 298
Issue: 9
Pages: 102342
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Publication
31662451 | J:284232
First Author: Dey S
Year: 2020
Journal: Mol Cancer Res
Title: miR-29a Is Repressed by MYC in Pancreatic Cancer and Its Restoration Drives Tumor-Suppressive Effects via Downregulation of LOXL2.
Volume: 18
Issue: 2
Pages: 311-323
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Publication
21803744 | J:175757
First Author: Allen TD
Year: 2011
Journal: Cancer Res
Title: Activated Notch1 induces lung adenomas in mice and cooperates with Myc in the generation of lung adenocarcinoma.
Volume: 71
Issue: 18
Pages: 6010-8
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Publication
23552735 | J:298317
 
First Author: Boudreaux SP
Year: 2012
Journal: Oncogenesis
Title: Genome-wide profiling reveals transcriptional repression of MYC as a core component of NR4A tumor suppression in acute myeloid leukemia.
Volume: 1
Pages: e19
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Publication
36150502 | J:353963
First Author: Murach KA
Year: 2022
Journal: J Biol Chem
Title: Multi-transcriptome analysis following an acute skeletal muscle growth stimulus yields tools for discerning global and MYC regulatory networks.
Volume: 298
Issue: 11
Pages: 102515
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Publication
34417556 | J:319627
First Author: Öztürk S
Year: 2022
Journal: Leukemia
Title: Longitudinal analyses of CLL in mice identify leukemia-related clonal changes including a Myc gain predicting poor outcome in patients.
Volume: 36
Issue: 2
Pages: 464-475
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Publication
9178772 | J:40998
First Author: Colley SM
Year: 1997
Journal: Oncogene
Title: Increased transcription of the E mu-myc transgene and mRNA stabilisation produce only a modest elevation in Myc protein.
Volume: 14
Issue: 22
Pages: 2735-9
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Publication
12736221 | J:83340
First Author: Frye M
Year: 2003
Journal: Development
Title: Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment.
Volume: 130
Issue: 12
Pages: 2793-808
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Publication
22030621 | J:316428
First Author: Höglund A
Year: 2011
Journal: Cell Cycle
Title: Chk2 deficiency in Myc overexpressing lymphoma cells elicits a synergistic lethal response in combination with PARP inhibition.
Volume: 10
Issue: 20
Pages: 3598-607
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Publication
35666804 | J:326990
First Author: Thege FI
Year: 2022
Journal: Cancer Res
Title: A Programmable In Vivo CRISPR Activation Model Elucidates the Oncogenic and Immunosuppressive Functions of MYC in Lung Adenocarcinoma.
Volume: 82
Issue: 15
Pages: 2761-2776
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Publication
17056717 | J:115637
First Author: Giuriato S
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch.
Volume: 103
Issue: 44
Pages: 16266-71
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Publication
18003922 | J:127626
First Author: Liu T
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis.
Volume: 104
Issue: 47
Pages: 18682-7
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Interaction Experiment
Wu M (2013)
Description: The ciliary protein cystin forms a regulatory complex with necdin to modulate Myc expression.
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Interaction Experiment
Laskowski AI (2013)
Description: Myc binds the pluripotency factor Utf1 through the basic-helix-loop-helix leucine zipper domain.
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Interaction Experiment
Guo A (2022)
Description: cBAF complex components and MYC cooperate early in CD8+ T cell fate.
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Allele
Tg(MMTV-Myc)164-4Led | MGI:2447518
Name: transgene insertion 164-4, Philip Leder
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
30650356 | J:277340
First Author: Santoro A
Year: 2019
Journal: Cell Rep
Title: p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value.
Volume: 26
Issue: 3
Pages: 624-638.e8
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Protein
P10166
Organism: Mus musculus/domesticus
Length: 368  
Fragment?: false
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Protein
Q9Z304
Organism: Mus musculus/domesticus
Length: 431  
Fragment?: false
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Protein
P03966
Organism: Mus musculus/domesticus
Length: 462  
Fragment?: false
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Protein
Q810L7
Organism: Mus musculus/domesticus
Length: 454  
Fragment?: false
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Protein
L0CUZ4
Organism: Mus musculus/domesticus
Length: 464  
Fragment?: false
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Protein
Q3UIE0
Organism: Mus musculus/domesticus
Length: 368  
Fragment?: false
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Protein
Q923F4
Organism: Mus musculus/domesticus
Length: 462  
Fragment?: false
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Protein
Q3UII1
Organism: Mus musculus/domesticus
Length: 462  
Fragment?: false
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GXD Expression
GXD Expression
 
Probe: MGI:1201966
Assay Type: RNA in situ
Annotation Date: 2020-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270125
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6400730
Age: embryonic day 17.5
Note: Expressed in a fraction of undifferentiated proliferating chondrocytes and overlapped with a subpopulation of Myc expressing cells.
Specimen Label: 3E
Detected: true
Specimen Num: 4
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Publication
16170382 | J:104078
First Author: Egler RA
Year: 2005
Journal: Oncogene
Title: Regulation of reactive oxygen species, DNA damage, and c-Myc function by peroxiredoxin 1.
Volume: 24
Issue: 54
Pages: 8038-50
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Publication
9182529 | J:41089
First Author: Leprince C
Year: 1997
Journal: J Biol Chem
Title: A new member of the amphiphysin family connecting endocytosis and signal transduction pathways.
Volume: 272
Issue: 24
Pages: 15101-5
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Publication
12183633 | J:78444
First Author: Lee E
Year: 2002
Journal: Science
Title: Amphiphysin 2 (Bin1) and T-tubule biogenesis in muscle.
Volume: 297
Issue: 5584
Pages: 1193-6
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Publication
12668730 | J:83477
First Author: Leprince C
Year: 2003
Journal: J Cell Sci
Title: Sorting nexin 4 and amphiphysin 2, a new partnership between endocytosis and intracellular trafficking.
Volume: 116
Issue: Pt 10
Pages: 1937-48
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Publication
27179792 | J:237310
First Author: Miyagawa T
Year: 2016
Journal: Hum Mol Genet
Title: BIN1 regulates BACE1 intracellular trafficking and amyloid-β production.
Volume: 25
Issue: 14
Pages: 2948-2958
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Publication
11154258 | J:77649
First Author: Quéva C
Year: 2001
Journal: Mol Cell Biol
Title: Targeted deletion of the S-phase-specific Myc antagonist Mad3 sensitizes neuronal and lymphoid cells to radiation-induced apoptosis.
Volume: 21
Issue: 3
Pages: 703-12
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Publication
35045331 | J:329125
First Author: Muto T
Year: 2022
Journal: Cell Stem Cell
Title: TRAF6 functions as a tumor suppressor in myeloid malignancies by directly targeting MYC oncogenic activity.
Volume: 29
Issue: 2
Pages: 298-314.e9
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Publication
1988138 | J:101629
First Author: Breuer M
Year: 1991
Journal: Cancer Res
Title: Carcinogen-induced lymphomagenesis in pim-1 transgenic mice: dose dependence and involvement of myc and ras.
Volume: 51
Issue: 3
Pages: 958-63
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Publication
9308245 | J:46020
 
First Author: Harris AW
Year: 1997
Journal: Curr Top Microbiol Immunol
Title: Lymphomas and plasmacytomas in transgenic mice involving bcl2, myc and v-abl.
Volume: 224
Pages: 221-30
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Publication
27773673 | J:249255
First Author: Xiao D
Year: 2016
Journal: Mol Cell
Title: Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feedforward Circuit Promoting Tumor Cell Survival.
Volume: 64
Issue: 3
Pages: 493-506
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Publication
8700908 | J:264356
First Author: Riu E
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Prevention of diabetic alterations in transgenic mice overexpressing Myc in the liver.
Volume: 93
Issue: 5
Pages: 2198-202
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Publication
2108842 | J:10411
First Author: Threadgill DW
Year: 1990
Journal: Cytogenet Cell Genet
Title: The thyroglobulin gene is syntenic with the MYC and MOS protooncogenes and carbonic anhydrase II and maps to chromosome 14 in cattle.
Volume: 53
Issue: 1
Pages: 32-6
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Publication
- | J:14088
 
First Author: Elliott RW
Year: 1986
Journal: Mouse News Lett
Title: A mouse "minisatellite".
Volume: 74
Pages: 115-7
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Publication
21098484 | J:168745
First Author: Holland S
Year: 2011
Journal: J Biol Chem
Title: The ubiquitin ligase MYCBP2 regulates transient receptor potential vanilloid receptor 1 (TRPV1) internalization through inhibition of p38 MAPK signaling.
Volume: 286
Issue: 5
Pages: 3671-80
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Publication
9238031 | J:42678
First Author: Stewart M
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): evidence for a new myc collaborating oncogene.
Volume: 94
Issue: 16
Pages: 8646-51
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Allele
Tg(MMTV-Myc)#Led | MGI:3621200
Name: transgene insertion, Philip Leder
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
38125876 | J:348410
 
First Author: Harafuji N
Year: 2023
Journal: Front Cell Dev Biol
Title: Differential regulation of MYC expression by PKHD1/Pkhd1 in human and mouse kidneys: phenotypic implications for recessive polycystic kidney disease.
Volume: 11
Pages: 1270980
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Publication
9362445 | J:43653
First Author: Jäger R
Year: 1997
Journal: Oncogene
Title: Overexpression of Bcl-2 inhibits alveolar cell apoptosis during involution and accelerates c-myc-induced tumorigenesis of the mammary gland in transgenic mice.
Volume: 15
Issue: 15
Pages: 1787-95
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Regulatory Region
MGI:7407300 | Rr331
Type: enhancer
Organism: mouse, laboratory
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Regulatory Region
MGI:7195550 | Rr307328
Type: enhancer
Organism: mouse, laboratory
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Publication
3261346 | J:9289
First Author: Baumbach WR
Year: 1988
Journal: J Virol
Title: Integration of the BALB/c ecotropic provirus into the colony-stimulating factor-1 growth factor locus in a myc retrovirus-induced murine monocyte tumor.
Volume: 62
Issue: 9
Pages: 3151-5
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Publication
9840930 | J:51319
First Author: Schmidt T
Year: 1998
Journal: Oncogene
Title: Zinc finger protein GFI-1 has low oncogenic potential but cooperates strongly with pim and myc genes in T-cell lymphomagenesis.
Volume: 17
Issue: 20
Pages: 2661-7
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Publication
15645495 | J:95921
First Author: Silva S
Year: 2005
Journal: Genes Chromosomes Cancer
Title: Location of Myc, Igh, and Igk on Robertsonian fusion chromosomes is inconsequential for Myc translocations and plasmacytoma development in mice, but Rb(6.15)-carrying tumors prefer Igk-Myc inversions over translocations.
Volume: 42
Issue: 4
Pages: 416-26
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Publication
34675406 | J:317029
First Author: Chen J
Year: 2022
Journal: Oncogene
Title: Lineage-restricted neoplasia driven by Myc defaults to small cell lung cancer when combined with loss of p53 and Rb in the airway epithelium.
Volume: 41
Issue: 1
Pages: 138-145
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Publication
37041291 | J:335164
   
First Author: Yang K
Year: 2023
Journal: Cell Death Differ
Title: Long non-coding RNA HIF1A-As2 and MYC form a double-positive feedback loop to promote cell proliferation and metastasis in KRAS-driven non-small cell lung cancer.
Pages: 1-17
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Allele
Mycbp2<tm1Adia> | MGI:3760639
Name: MYC binding protein 2, E3 ubiquitin protein ligase; targeted mutation 1, Aaron DiAntonio
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Mycbp2<tm1.1Adia> | MGI:3760640
Name: MYC binding protein 2, E3 ubiquitin protein ligase; targeted mutation 1.1, Aaron DiAntonio
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Mycbp2<magsp> | MGI:3777465
 
Name: MYC binding protein 2, E3 ubiquitin protein ligase; Magellum splicing defective
Allele Type: Chemically induced (ENU)
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Allele
Mycbp2<m274-4Tpo> | MGI:3849603
 
Name: MYC binding protein 2, E3 ubiquitin protein ligase; mutation 274-4, Timothy P O'Brien
Allele Type: Chemically induced (ENU)
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Allele
Mycbp2<Gt(CSI367)Byg> | MGI:3879221
 
Name: MYC binding protein 2, E3 ubiquitin protein ligase; gene trap CSI367, BayGenomics
Allele Type: Gene trapped
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Allele
Mycbp2<Gt(XC692)Byg> | MGI:4124736
 
Name: MYC binding protein 2, E3 ubiquitin protein ligase; gene trap XC692, BayGenomics
Allele Type: Gene trapped
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Allele
Mycbp2<Gt(RRT219)Byg> | MGI:4340597
 
Name: MYC binding protein 2, E3 ubiquitin protein ligase; gene trap RRT219, BayGenomics
Allele Type: Gene trapped
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Allele
Mycbp2<tm1.1Klsc> | MGI:4939601
Name: MYC binding protein 2, E3 ubiquitin protein ligase; targeted mutation 1.1, Klaus Scholich
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Mycbp2<m7Bei> | MGI:5505462
 
Name: MYC binding protein 2, E3 ubiquitin protein ligase; mutation 7 David R Beier
Allele Type: Chemically induced (ENU)
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Allele
Myct1<em1(IMPC)Mbp> | MGI:6152520
Name: myc target 1; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Mycbp2<em1Cya> | MGI:7585194
Name: MYC binding protein 2, E3 ubiquitin protein ligase; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:7590066 | C57BL/6J-Myct1<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Mycbp2<em2Cya> | MGI:7794784
Name: MYC binding protein 2, E3 ubiquitin protein ligase; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Genotype
Genotype
Symbol: Myct1/Myct1
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
2473006 | J:29010
First Author: Edmondson DG
Year: 1989
Journal: Genes Dev
Title: A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program.
Volume: 3
Issue: 5
Pages: 628-40
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Publication
11896625 | J:75563
First Author: Yu D
Year: 2002
Journal: Oncogene
Title: A non-transgenic mouse model for B-cell lymphoma: in vivo infection of p53-null bone marrow progenitors by a Myc retrovirus is sufficient for tumorigenesis.
Volume: 21
Issue: 12
Pages: 1922-7
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Publication
18031680 | J:132726
First Author: Lewcock JW
Year: 2007
Journal: Neuron
Title: The ubiquitin ligase Phr1 regulates axon outgrowth through modulation of microtubule dynamics.
Volume: 56
Issue: 4
Pages: 604-20
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Publication
27926480 | -
First Author: Raffeiner P
Year: 2017
Journal: Oncotarget
Title: Calcium-dependent binding of Myc to calmodulin.
Volume: 8
Issue: 2
Pages: 3327-3343
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Publication
19391113 | J:149893
First Author: Hagarman JA
Year: 2009
Journal: Genesis
Title: An essential gene mutagenesis screen across the highly conserved piebald deletion region of mouse chromosome 14.
Volume: 47
Issue: 6
Pages: 392-403
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Protein
Q7TPH6
Organism: Mus musculus/domesticus
Length: 4749  
Fragment?: false
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Publication
26474282 | J:312573
First Author: Yuwanita I
Year: 2015
Journal: Oncotarget
Title: Increased metastasis with loss of E2F2 in Myc-driven tumors.
Volume: 6
Issue: 35
Pages: 38210-24
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Protein
Q9WU28
Organism: Mus musculus/domesticus
Length: 154  
Fragment?: false
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Protein
Q7TPH6-2
Organism: Mus musculus/domesticus
Length: 4746  
Fragment?: false
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Protein
P24452
Organism: Mus musculus/domesticus
Length: 352  
Fragment?: false
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Regulatory Region
MGI:5750929 | Rr38
Type: enhancer
Organism: mouse, laboratory
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Regulatory Region
MGI:7643475 | Rr478
Type: enhancer
Organism: mouse, laboratory
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Regulatory Region
MGI:7643396 | Rr477
Type: enhancer
Organism: mouse, laboratory
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Publication
2832150 | J:46455
First Author: Suda Y
Year: 1987
Journal: EMBO J
Title: Driven by the same Ig enhancer and SV40 T promoter ras induced lung adenomatous tumors, myc induced pre-B cell lymphomas and SV40 large T gene a variety of tumors in transgenic mice.
Volume: 6
Issue: 13
Pages: 4055-65
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Publication
16904174 | -
First Author: Takahashi K
Year: 2006
Journal: Cell
Title: Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.
Volume: 126
Issue: 4
Pages: 663-76
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