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Search results 2501 to 2600 out of 2847 for Fgfr2

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Genotype
Genotype
Symbol: Fgfr1/Fgfr1
Background: involves: 129S4/SvJae * NIH Black Swiss
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgfr1/Fgfr1<+>
Background: D2.129S6(Cg)-Fgfr1
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:14705 | Pfeiffer syndrome
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HT Experiment
GSE197369 | Transcripts identified by microarray analysis that were deregulated in E14.5 Tbx18(cre/+);FGFR1(fl/fl);FGFR2(fl/fl) (Fgfr1/2cDKO) ureters
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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Protein Coding Gene
MGI:1099809 | Fgf10
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:95522 | Fgfr1
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Bey | MGI:1889298
   
Name: bulgy-eye
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Allele
Fgfr2<tm4Lni> | MGI:3053095
Name: fibroblast growth factor receptor 2; targeted mutation 4, Peter Lonai
Allele Type: Targeted
Attribute String: Humanized sequence
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Allele
Fgfr2<tm1Schl> | MGI:3699313
Name: fibroblast growth factor receptor 2; targeted mutation 1, Joseph Schlessinger
Allele Type: Targeted
Attribute String: Humanized sequence
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Genotype
Genotype
Symbol: Fgfr2/Fgfr2<+>
Background: involves: 129 * C57BL/6 * FVB/N
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:0050660 | Beare-Stevenson cutis gyrata syndrome
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DO Term
DOID:0111337 | Jackson-Weiss syndrome
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Allele
Gt(ROSA)26Sor<em63(CAG-FGFR2,-luc,-EGFP)Smoc> | MGI:7290072
Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 63, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Heritable Phenotypic Marker
MGI:1276118 | Bey
Type: heritable_phenotypic_marker
Organism: mouse, laboratory
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Allele
Fgf10<tm1Wss> | MGI:1927833
Name: fibroblast growth factor 10; targeted mutation 1, W Scott Simonet
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Bey/Bey<+>
Background: 129S/SvEv-Bey
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgfr2/Fgfr2<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgfr2/Fgfr2<+>
Background: involves: 129S1/Sv
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:2339 | Crouzon syndrome
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DO Term
DOID:0050462 | Antley-Bixler syndrome with disordered steroidogenesis
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DO Term
DOID:0060992 | bent bone dysplasia syndrome 1
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HT Experiment
GSE178093 | Transcripts identified by microarray analysis that were deregulated in E13.5 Pax-2cre;Fgfr1(fl/?);Fgfr2(fl/fl) (Fgfr2cKO) ureters.
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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Allele
Tg(Pbsn-FGFR2_iiib*)#Ng | MGI:2448655
Name: transgene insertion, Norman M Greenberg
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence, Modified isoform(s)
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Allele
Col1a1<tm4(CAG-FGFR2_iIIIb*K660N)Kkw> | MGI:5661319
Name: collagen, type I, alpha 1; targeted mutation 4, Kwok-Kin Wong
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
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Allele
Col1a1<tm5(CAG-FGFR2_iIIIb*W290C)Kkw> | MGI:5661327
Name: collagen, type I, alpha 1; targeted mutation 5, Kwok-Kin Wong
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
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Strain
MGI:6354837 | C57BL/6JSmoc-Gt(ROSA)26Sor<em63(CAG-FGFR2,-luc,-EGFP)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Protein Coding Gene
MGI:1919764 | Fgfbp3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1096350 | Fgfbp1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
O70514
Organism: Mus musculus/domesticus
Length: 251  
Fragment?: false
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Protein
Q1HCM0
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: false
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HT Experiment
E-GEOD-41260 | Expression Profiles of E11.5 Mouse Optic Fissure
Series Id: GSE41260
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-54801 | Gene regulation by Ffr2 in the conjunctival epithelium
Series Id: GSE54801
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Protein Coding Gene
MGI:97791 | Ptbp1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:104820 | Hnrnpa1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P49312
Organism: Mus musculus/domesticus
Length: 320  
Fragment?: false
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Protein
P17225
Organism: Mus musculus/domesticus
Length: 527  
Fragment?: false
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Genotype
Genotype
Symbol: Fgf10/Fgf10<+>
Background: involves: 129X1/SvJ
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:0050331 | lacrimoauriculodentodigital syndrome 1
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Gene
5447 | POR
Type: gene
Organism: human
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Strain
MGI:5451086 | B6.129-Fgfr2<tm3Ewj>
Attribute String: congenic, mutant strain, targeted mutation
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Allele
Fgfr2<tm2.1Sor> | MGI:5903019
Name: fibroblast growth factor receptor 2; targeted mutation 2.1, Philippe Soriano
Allele Type: Targeted
Attribute String: No functional change, Reporter
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Genotype
Genotype
Symbol: Tg(Pbsn-FGFR2_iiib*)#Ng/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Col1a1/Col1a1<+>
Background: involves: 129S4/SvJae * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Col1a1/Col1a1<+> Trp53/Trp53
Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Col1a1/Col1a1<+> Trp53/Trp53
Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
GSE121780 | Mandibular dysmorphogenesis due to abnormal osteogenic activity in FGFR2-related craniosynostosis mouse models
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Gene
2260 | FGFR1
Type: gene
Organism: human
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Strain
MGI:6716927 | 129S4/SvJaeSor-Fgfr2<tm2.1Sor>
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:5903020 | 129S4/SvJae-Fgfr2<tm2.1Sor>/J
Attribute String: targeted mutation, mutant strain, coisogenic
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Genotype
Genotype
Symbol: Fgfr2/Fgfr2<+>
Background: 129S4/SvJaeSor-Fgfr2
Zygosity: ht
Has Mutant Allele: true
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Protein Coding Gene
MGI:1345138 | Spry2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:894316 | Mknk1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
O08605
Organism: Mus musculus/domesticus
Length: 427  
Fragment?: false
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Protein
Q9QXV8
Organism: Mus musculus/domesticus
Length: 315  
Fragment?: false
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Protein
P36363
Organism: Mus musculus/domesticus
Length: 194  
Fragment?: false
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Publication
12492503 | J:80821
First Author: Foster BA
Year: 2002
Journal: Differentiation
Title: Enforced expression of FGF-7 promotes epithelial hyperplasia whereas a dominant negative FGFR2iiib promotes the emergence of neuroendocrine phenotype in prostate glands of transgenic mice.
Volume: 70
Issue: 9-10
Pages: 624-32
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Genotype
Genotype
Symbol: Tg(Arr2/Pbsn-FGFR1K656E)1Wmck/? Tg(Pbsn-FGFR2_iiib*)#Ng/?
Background: involves: FVB
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgfr2/Fgfr2<+> Pdgfra/Pdgfra<+>
Background: involves: 129S4/SvJaeSor
Zygosity: cx
Has Mutant Allele: true
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Protein
P21803
Organism: Mus musculus/domesticus
Length: 821  
Fragment?: false
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Protein
O35565
Organism: Mus musculus/domesticus
Length: 209  
Fragment?: false
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Protein Domain
IPR034431 | ESRP2
Type: Family
Description: ESRP2 has been identified as an epithelial cell type-specific regulator of fibroblast growth factor receptor 2 (FGFR2) splicing []. It is required for expression of epithelial FGFR2-IIIb and the regulation of CD44, CTNND1 (also termed p120-Catenin) and ENAH (also termed hMena) splicing. It enhances epithelial-specific exons of CD44 and ENAH, silences mesenchymal exons of CTNND1, or both within FGFR2 []. ESRP2 contains three RNA recognition motifs (RRMs).
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Protein
P15656
Organism: Mus musculus/domesticus
Length: 264  
Fragment?: false
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Protein
P15655
Organism: Mus musculus/domesticus
Length: 154  
Fragment?: false
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Protein
P21658
Organism: Mus musculus/domesticus
Length: 208  
Fragment?: false
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Publication
8576175 | J:30894
First Author: Santos-Ocampo S
Year: 1996
Journal: J Biol Chem
Title: Expression and biological activity of mouse fibroblast growth factor-9.
Volume: 271
Issue: 3
Pages: 1726-31
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HT Experiment
GSE90821 | ESRP1 mutations cause hearing loss due to defects in alternative splicing that disrupt cochlear development
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE143217 | Epithelial expressions of Gata4 and Sox2 regulate murine specification of the squamous-columnar junction via MAPK/ERK signaling
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Genotype
Genotype
Symbol: Tg(Pbsn-FGFR1*K656E)#Wmck/? Tg(Pbsn-FGFR2_iiib*)#Ng/?
Background: involves: FVB
Zygosity: cx
Has Mutant Allele: true
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Protein Coding Gene
MGI:2135965 | Frs3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:95521 | Fgf7
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:88190 | Braf
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P28028
Organism: Mus musculus/domesticus
Length: 751  
Fragment?: false
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Protein
Q91WJ0
Organism: Mus musculus/domesticus
Length: 492  
Fragment?: false
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Publication
19829082 | -
First Author: Warzecha CC
Year: 2009
Journal: RNA Biol
Title: The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events.
Volume: 6
Issue: 5
Pages: 546-62
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Protein Coding Gene
MGI:1914362 | Fgf22
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:98086 | Polr2a
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1915955 | Gtf2f2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1923848 | Gtf2f1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1916491 | Polr2d
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1914960 | Polr2g
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2388280 | Polr2b
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:109582 | Polr2j
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1917170 | Polr2i
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:95517 | Fgf3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:108088 | Gab1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:109299 | Polr2c
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:88279 | Cbl
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P22682
Organism: Mus musculus/domesticus
Length: 913  
Fragment?: false
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Protein
Q9ESS2
Organism: Mus musculus/domesticus
Length: 162  
Fragment?: false
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Protein
Q9QYY0
Organism: Mus musculus/domesticus
Length: 695  
Fragment?: false
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Protein
Q3THK3
Organism: Mus musculus/domesticus
Length: 508  
Fragment?: false
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Protein
Q8R0A0
Organism: Mus musculus/domesticus
Length: 249  
Fragment?: false
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Protein
Q9D7M8
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: false
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Protein
P62488
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: false
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Protein
O08740
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: false
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Protein
P08775
Organism: Mus musculus/domesticus
Length: 1970  
Fragment?: false
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Protein
Q8CFI7
Organism: Mus musculus/domesticus
Length: 1174  
Fragment?: false
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Protein
P97760
Organism: Mus musculus/domesticus
Length: 275  
Fragment?: false
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Protein
P05524
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: false
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Protein
P60898
Organism: Mus musculus/domesticus
Length: 125  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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