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Search results 2501 to 2600 out of 2672 for Mapt

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Type Details Score
Publication
24244584 | J:209696
First Author: Ding F
Year: 2013
Journal: PLoS One
Title: Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention.
Volume: 8
Issue: 11
Pages: e79977
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Publication
23683389 | J:284655
First Author: Giannopoulos PF
Year: 2013
Journal: Biol Psychiatry
Title: 5-lipoxygenase activating protein reduction ameliorates cognitive deficit, synaptic dysfunction, and neuropathology in a mouse model of Alzheimer's disease.
Volume: 74
Issue: 5
Pages: 348-56
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Publication
38941459 | J:350513
First Author: Li C
Year: 2024
Journal: Sci Adv
Title: TGR5 deficiency in excitatory neurons ameliorates Alzheimer's pathology by regulating APP processing.
Volume: 10
Issue: 26
Pages: eado1855
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Publication
- | J:343012
     
First Author: Edwards GA
Year: 2023
Journal: bioRxiv
Title: TMEM106B coding variant is protective and deletion detrimental in a mouse model of tauopathy
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Publication
30068389 | J:319825
First Author: Maziuk BF
Year: 2018
Journal: Acta Neuropathol Commun
Title: RNA binding proteins co-localize with small tau inclusions in tauopathy.
Volume: 6
Issue: 1
Pages: 71
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Publication
14642273 | J:104240
First Author: Cruz JC
Year: 2003
Journal: Neuron
Title: Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles.
Volume: 40
Issue: 3
Pages: 471-83
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Publication
37642942 | J:347913
 
First Author: Ralvenius WT
Year: 2023
Journal: J Exp Med
Title: A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation.
Volume: 220
Issue: 11
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Publication
36536457 | J:338954
First Author: Kim DW
Year: 2022
Journal: Mol Neurodegener
Title: Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes.
Volume: 17
Issue: 1
Pages: 83
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Publication
39096489 | J:353285
First Author: Zwang TJ
Year: 2024
Journal: Cell Rep
Title: Neurofibrillary tangle-bearing neurons have reduced risk of cell death in mice with Alzheimer's pathology.
Volume: 43
Issue: 8
Pages: 114574
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Publication
25231903 | J:217304
First Author: Tagawa K
Year: 2015
Journal: Hum Mol Genet
Title: Comprehensive phosphoproteome analysis unravels the core signaling network that initiates the earliest synapse pathology in preclinical Alzheimer's disease brain.
Volume: 24
Issue: 2
Pages: 540-58
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Publication
32557778 | J:311338
First Author: Ferreira S
Year: 2020
Journal: J Neurosci Res
Title: Amyloidosis is associated with thicker myelin and increased oligodendrogenesis in the adult mouse brain.
Volume: 98
Issue: 10
Pages: 1905-1932
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Publication
29346778 | J:324542
First Author: Friedman BA
Year: 2018
Journal: Cell Rep
Title: Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer's Disease Not Evident in Mouse Models.
Volume: 22
Issue: 3
Pages: 832-847
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Publication
39504519 | J:359514
     
First Author: Welikovitch LA
Year: 2024
Journal: Brain
Title: Tau, synapse loss and gliosis progress in an Alzheimer's mouse model after amyloid-β immunotherapy.
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Publication
37075107 | J:335302
First Author: Licht-Murava A
Year: 2023
Journal: Sci Adv
Title: Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines.
Volume: 9
Issue: 16
Pages: eade1282
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Publication
33289969 | J:355625
First Author: Morshed N
Year: 2020
Journal: Mol Syst Biol
Title: Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration.
Volume: 16
Issue: 12
Pages: e9819
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Publication
34148071 | J:311242
First Author: Ries M
Year: 2021
Journal: Brain
Title: Annexin A1 restores cerebrovascular integrity concomitant with reduced amyloid-β and tau pathology.
Volume: 144
Issue: 5
Pages: 1526-1541
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Publication
37287063 | J:337840
First Author: Bianchi C
Year: 2023
Journal: Alzheimers Res Ther
Title: P2X7 receptor inhibition ameliorates ubiquitin-proteasome system dysfunction associated with Alzheimer's disease.
Volume: 15
Issue: 1
Pages: 105
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Genotype
Genotype
Symbol: Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/Tg(APPSwe,tauP301L)1Lfa
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/?
Background: B6.Cg-Psen1 Tg(APPSwe,tauP301L)1Lfa
Zygosity: cx
Has Mutant Allele: true
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Publication
21673655 | J:196042
First Author: Yamagishi S
Year: 2011
Journal: EMBO J
Title: FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons.
Volume: 30
Issue: 14
Pages: 2920-33
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Publication
21835156 | J:176301
First Author: Montgomery SL
Year: 2011
Journal: Am J Pathol
Title: Ablation of TNF-RI/RII expression in Alzheimer's disease mice leads to an unexpected enhancement of pathology: implications for chronic pan-TNF-α suppressive therapeutic strategies in the brain.
Volume: 179
Issue: 4
Pages: 2053-70
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Publication
36170815 | J:329919
First Author: Rangan P
Year: 2022
Journal: Cell Rep
Title: Fasting-mimicking diet cycles reduce neuroinflammation to attenuate cognitive decline in Alzheimer's models.
Volume: 40
Issue: 13
Pages: 111417
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Publication
23147109 | J:203656
 
First Author: Waite MR
Year: 2013
Journal: Mol Cell Neurosci
Title: Pleiotropic and isoform-specific functions for Pitx2 in superior colliculus and hypothalamic neuronal development.
Volume: 52
Pages: 128-39
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Publication
25339759 | J:217151
First Author: Shibuya Y
Year: 2014
Journal: J Neurosci
Title: Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearance.
Volume: 34
Issue: 43
Pages: 14484-501
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Publication
20133765 | J:157545
First Author: Bryleva EY
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD.
Volume: 107
Issue: 7
Pages: 3081-6
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Publication
31004063 | J:274643
First Author: Xiang J
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Delta-secretase-cleaved Tau antagonizes TrkB neurotrophic signalings, mediating Alzheimer's disease pathologies.
Volume: 116
Issue: 18
Pages: 9094-9102
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Publication
38906984 | J:350176
First Author: Jong Huat T
Year: 2024
Journal: Sci Rep
Title: The impact of astrocytic NF-κB on healthy and Alzheimer's disease brains.
Volume: 14
Issue: 1
Pages: 14305
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Publication
30850634 | J:275633
First Author: Caberlotto L
Year: 2019
Journal: Sci Rep
Title: Cross-disease analysis of Alzheimer's disease and type-2 Diabetes highlights the role of autophagy in the pathophysiology of two highly comorbid diseases.
Volume: 9
Issue: 1
Pages: 3965
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Publication
18021291 | J:141555
First Author: Lopez JR
Year: 2008
Journal: J Neurochem
Title: Increased intraneuronal resting [Ca2+] in adult Alzheimer's disease mice.
Volume: 105
Issue: 1
Pages: 262-71
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Publication
29725016 | J:262986
First Author: Wang ZH
Year: 2018
Journal: Nat Commun
Title: C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer's disease.
Volume: 9
Issue: 1
Pages: 1784
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Publication
38555992 | J:351247
 
First Author: Wang J
Year: 2024
Journal: Brain Behav Immun
Title: A TrkB cleavage fragment in hippocampus promotes Depressive-Like behavior in mice.
Volume: 119
Pages: 56-83
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Publication
29018038 | J:248850
First Author: Pera M
Year: 2017
Journal: EMBO J
Title: Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease.
Volume: 36
Issue: 22
Pages: 3356-3371
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Publication
21704011 | J:174403
First Author: Medeiros R
Year: 2011
Journal: Am J Pathol
Title: Loss of muscarinic M1 receptor exacerbates Alzheimer's disease-like pathology and cognitive decline.
Volume: 179
Issue: 2
Pages: 980-91
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Publication
35902630 | J:351375
First Author: Yang Y
Year: 2023
Journal: Mol Psychiatry
Title: Adeno-associated virus (AAV) 9-mediated gene delivery of Nurr1 and Foxa2 ameliorates symptoms and pathologies of Alzheimer disease model mice by suppressing neuro-inflammation and glial pathology.
Volume: 28
Issue: 12
Pages: 5359-5374
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Publication
27155503 | J:242424
First Author: Hargis KE
Year: 2017
Journal: Behav Brain Res
Title: Transcriptional signatures of brain aging and Alzheimer's disease: What are our rodent models telling us?
Volume: 322
Issue: Pt B
Pages: 311-328
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Publication
31434879 | J:279495
First Author: Spangenberg E
Year: 2019
Journal: Nat Commun
Title: Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model.
Volume: 10
Issue: 1
Pages: 3758
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Publication
35198070 | J:327457
First Author: Cai CZ
Year: 2022
Journal: Theranostics
Title: Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease models.
Volume: 12
Issue: 4
Pages: 1738-1755
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Publication
37421950 | J:339320
First Author: Xiang J
Year: 2023
Journal: Cell
Title: Development of an α-synuclein positron emission tomography tracer for imaging synucleinopathies.
Volume: 186
Issue: 16
Pages: 3350-3367.e19
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Publication
39110781 | J:353793
First Author: Han J
Year: 2024
Journal: Sci Transl Med
Title: Engineered exosomes with a photoinducible protein delivery system enable CRISPR-Cas-based epigenome editing in Alzheimer's disease.
Volume: 16
Issue: 759
Pages: eadi4830
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Publication
21829458 | J:284814
First Author: Bianchi FT
Year: 2011
Journal: PLoS One
Title: The collagen chaperone HSP47 is a new interactor of APP that affects the levels of extracellular beta-amyloid peptides.
Volume: 6
Issue: 7
Pages: e22370
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Publication
25447943 | J:231418
 
First Author: Hohsfield LA
Year: 2014
Journal: Mol Cell Neurosci
Title: Vascular pathology of 20-month-old hypercholesterolemia mice in comparison to triple-transgenic and APPSwDI Alzheimer's disease mouse models.
Volume: 63
Pages: 83-95
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Publication
29501742 | J:273677
First Author: Li H
Year: 2018
Journal: Biochem Biophys Res Commun
Title: FTO is involved in Alzheimer's disease by targeting TSC1-mTOR-Tau signaling.
Volume: 498
Issue: 1
Pages: 234-239
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Publication
23955714 | J:202038
First Author: Pietri M
Year: 2013
Journal: Nat Med
Title: PDK1 decreases TACE-mediated α-secretase activity and promotes disease progression in prion and Alzheimer's diseases.
Volume: 19
Issue: 9
Pages: 1124-31
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Publication
22367970 | J:183771
First Author: Manczak M
Year: 2012
Journal: Hum Mol Genet
Title: Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage.
Volume: 21
Issue: 11
Pages: 2538-47
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Publication
22926141 | J:188922
First Author: Manczak M
Year: 2012
Journal: Hum Mol Genet
Title: Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease.
Volume: 21
Issue: 23
Pages: 5131-46
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Publication
34850492 | J:353175
First Author: Nguyen P
Year: 2022
Journal: Microsc Res Tech
Title: An easy brain thick-section-clearing protocol to observe antigens in the brains of neurological disease mouse models by conventional epifluorescence and confocal laser scanning microscopy.
Volume: 85
Issue: 4
Pages: 1618-1626
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Publication
36254251 | J:352636
First Author: Yu H
Year: 2022
Journal: MedComm (2020)
Title: Integrated analyses of brain and platelet omics reveal their common altered and driven molecules in Alzheimer's disease.
Volume: 3
Issue: 4
Pages: e180
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Publication
33893290 | J:304519
First Author: Baglietto-Vargas D
Year: 2021
Journal: Nat Commun
Title: Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology.
Volume: 12
Issue: 1
Pages: 2421
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Publication
32745992 | J:311234
 
First Author: Crapser JD
Year: 2020
Journal: EBioMedicine
Title: Microglia facilitate loss of perineuronal nets in the Alzheimer's disease brain.
Volume: 58
Pages: 102919
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Publication
38750512 | J:352622
First Author: Zhang N
Year: 2024
Journal: Alzheimers Res Ther
Title: Cholecystokinin B receptor agonists alleviates anterograde amnesia in cholecystokinin-deficient and aged Alzheimer's disease mice.
Volume: 16
Issue: 1
Pages: 109
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Publication
27470171 | J:236530
First Author: Höfling C
Year: 2016
Journal: Aging Cell
Title: Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein-specific antibodies.
Volume: 15
Issue: 5
Pages: 953-63
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Publication
37060096 | J:335721
First Author: Wu D
Year: 2023
Journal: Mol Neurodegener
Title: Targeting a vulnerable septum-hippocampus cholinergic circuit in a critical time window ameliorates tau-impaired memory consolidation.
Volume: 18
Issue: 1
Pages: 23
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Publication
34303222 | J:311302
 
First Author: Russo ML
Year: 2021
Journal: Neurobiol Aging
Title: Variability in sub-threshold signaling linked to Alzheimer's disease emerges with age and amyloid plaque deposition in mouse ventral CA1 pyramidal neurons.
Volume: 106
Pages: 207-222
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Publication
31858697 | J:358332
First Author: Song JX
Year: 2020
Journal: Aging Cell
Title: A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models.
Volume: 19
Issue: 2
Pages: e13069
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Publication
25947203 | J:351760
First Author: Plagg B
Year: 2015
Journal: Biogerontology
Title: Platelet dysfunction in hypercholesterolemia mice, two Alzheimer's disease mouse models and in human patients with Alzheimer's disease.
Volume: 16
Issue: 4
Pages: 543-58
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Publication
31164420 | J:279242
First Author: Bahn G
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer's models.
Volume: 116
Issue: 25
Pages: 12516-12523
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Publication
37409006 | J:346956
 
First Author: Weigel TK
Year: 2023
Journal: Front Aging Neurosci
Title: Altered circadian behavior and light sensing in mouse models of Alzheimer's disease.
Volume: 15
Pages: 1218193
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Publication
36843263 | J:338361
First Author: Kim SH
Year: 2023
Journal: Autophagy
Title: Endolysosomal impairment by binding of amyloid beta or MAPT/Tau to V-ATPase and rescue via the HYAL-CD44 axis in Alzheimer disease.
Volume: 19
Issue: 8
Pages: 2318-2337
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Publication
39394468 | J:358361
First Author: Guo Y
Year: 2024
Journal: EMBO Mol Med
Title: Targeting USP11 regulation by a novel lithium-organic coordination compound improves neuropathologies and cognitive functions in Alzheimer transgenic mice.
Volume: 16
Issue: 11
Pages: 2856-2881
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Publication
34522902 | J:359101
First Author: Hegedüs P
Year: 2021
Journal: STAR Protoc
Title: Training protocol for probabilistic Pavlovian conditioning in mice using an open-source head-fixed setup.
Volume: 2
Issue: 3
Pages: 100795
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Publication
37298502 | J:348455
 
First Author: Choi Y
Year: 2023
Journal: Int J Mol Sci
Title: Capacitive Electrode-Based Electric Field Treatments on Redox-Toxic Iron Deposits in Transgenic AD Mouse Models: The Electroceutical Targeting of Alzheimer's Disease Feasibility Study.
Volume: 24
Issue: 11
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Publication
32920368 | J:348446
 
First Author: Danielyan L
Year: 2020
Journal: EBioMedicine
Title: Cell motility and migration as determinants of stem cell efficacy.
Volume: 60
Pages: 102989
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Publication
36703981 | J:355400
 
First Author: Daini E
Year: 2022
Journal: Front Immunol
Title: Melanocortin receptor agonist NDP-α-MSH improves cognitive deficits and microgliosis but not amyloidosis in advanced stages of AD progression in 5XFAD and 3xTg mice.
Volume: 13
Pages: 1082036
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Publication
26159193 | J:264838
First Author: Plagg B
Year: 2015
Journal: Curr Alzheimer Res
Title: Increased Acetylation of Histone H4 at Lysine 12 (H4K12) in Monocytes of Transgenic Alzheimer's Mice and in Human Patients.
Volume: 12
Issue: 8
Pages: 752-60
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Publication
36451854 | J:348479
First Author: Yang H
Year: 2022
Journal: Theranostics
Title: Adoptive therapy with amyloid-β specific regulatory T cells alleviates Alzheimer's disease.
Volume: 12
Issue: 18
Pages: 7668-7680
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Publication
26969629 | J:351702
First Author: Roddick KM
Year: 2016
Journal: Chem Senses
Title: Sex and Genotype Differences in Odor Detection in the 3×Tg-AD and 5XFAD Mouse Models of Alzheimer's Disease at 6 Months of Age.
Volume: 41
Issue: 5
Pages: 433-40
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Publication
30525042 | J:268837
 
First Author: Sabbir MG
Year: 2018
Journal: Front Mol Biosci
Title: Loss of Ca2+/Calmodulin Dependent Protein Kinase Kinase 2 Leads to Aberrant Transferrin Phosphorylation and Trafficking: A Potential Biomarker for Alzheimer's Disease.
Volume: 5
Pages: 99
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Publication
33902708 | J:348523
First Author: Park JS
Year: 2021
Journal: Acta Neuropathol Commun
Title: Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer's disease.
Volume: 9
Issue: 1
Pages: 78
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Publication
38117656 | J:355509
First Author: Xiang J
Year: 2024
Journal: STAR Protoc
Title: Protocol for screening α-synuclein PET tracer candidates in vitro and ex vivo.
Volume: 5
Issue: 1
Pages: 102788
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Publication
24694184 | J:285067
 
First Author: Guzmán EA
Year: 2014
Journal: Mol Neurodegener
Title: Abundance of Aβ₅-x like immunoreactivity in transgenic 5XFAD, APP/PS1KI and 3xTG mice, sporadic and familial Alzheimer's disease.
Volume: 9
Pages: 13
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Publication
33287900 | J:313473
First Author: Bevan RJ
Year: 2020
Journal: Acta Neuropathol Commun
Title: Retinal ganglion cell degeneration correlates with hippocampal spine loss in experimental Alzheimer's disease.
Volume: 8
Issue: 1
Pages: 216
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Publication
33192524 | J:313486
 
First Author: Iyaswamy A
Year: 2020
Journal: Front Pharmacol
Title: Yuan-Hu Zhi Tong Prescription Mitigates Tau Pathology and Alleviates Memory Deficiency in the Preclinical Models of Alzheimer's Disease.
Volume: 11
Pages: 584770
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Publication
29024660 | J:253213
First Author: Zhao Y
Year: 2017
Journal: Neuron
Title: Amyloid Beta Peptides Block New Synapse Assembly by Nogo Receptor-Mediated Inhibition of T-Type Calcium Channels.
Volume: 96
Issue: 2
Pages: 355-372.e6
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Publication
26214837 | J:228830
First Author: Zenaro E
Year: 2015
Journal: Nat Med
Title: Neutrophils promote Alzheimer's disease-like pathology and cognitive decline via LFA-1 integrin.
Volume: 21
Issue: 8
Pages: 880-6
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Publication
32832679 | J:327386
First Author: Chen C
Year: 2020
Journal: Sci Adv
Title: Gut dysbiosis contributes to amyloid pathology, associated with C/EBPβ/AEP signaling activation in Alzheimer's disease mouse model.
Volume: 6
Issue: 31
Pages: eaba0466
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Publication
18800967 | J:141307
First Author: Ribe EM
Year: 2008
Journal: Biochem J
Title: Mechanisms of neuronal death in disease: defining the models and the players.
Volume: 415
Issue: 2
Pages: 165-82
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Publication
21235806 | J:194454
First Author: Fonseca MI
Year: 2011
Journal: J Neuroinflammation
Title: Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease.
Volume: 8
Issue: 1
Pages: 4
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Publication
37867176 | J:358195
First Author: Iyaswamy A
Year: 2023
Journal: Signal Transduct Target Ther
Title: Fe65-engineered neuronal exosomes encapsulating corynoxine-B ameliorate cognition and pathology of Alzheimer's disease.
Volume: 8
Issue: 1
Pages: 404
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Publication
20305648 | J:159680
First Author: Fuhrmann M
Year: 2010
Journal: Nat Neurosci
Title: Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease.
Volume: 13
Issue: 4
Pages: 411-3
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Publication
37308288 | J:337909
 
First Author: Sanna PP
Year: 2023
Journal: eNeuro
Title: A History of Repeated Alcohol Intoxication Promotes Cognitive Impairment and Gene Expression Signatures of Disease Progression in the 3xTg Mouse Model of Alzheimer's Disease.
Volume: 10
Issue: 7
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Publication
19664757 | J:281363
First Author: España J
Year: 2010
Journal: Biol Psychiatry
Title: Intraneuronal beta-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice.
Volume: 67
Issue: 6
Pages: 513-21
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Publication
29358916 | J:310530
 
First Author: Yang S
Year: 2017
Journal: Front Aging Neurosci
Title: Reducing the Levels of Akt Activation by PDK1 Knock-in Mutation Protects Neuronal Cultures against Synthetic Amyloid-Beta Peptides.
Volume: 9
Pages: 435
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Publication
38288580 | J:361050
First Author: Tapella L
Year: 2024
Journal: Glia
Title: Genetic deletion of astrocytic calcineurin B1 prevents cognitive impairment and neuropathology development in acute and chronic mouse models of Alzheimer's disease.
Volume: 72
Issue: 5
Pages: 899-915
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Publication
30635592 | J:275422
First Author: Creighton SD
Year: 2019
Journal: Sci Rep
Title: Dissociable cognitive impairments in two strains of transgenic Alzheimer's disease mice revealed by a battery of object-based tests.
Volume: 9
Issue: 1
Pages: 57
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Publication
28826672 | J:271996
First Author: Wang ZH
Year: 2017
Journal: Mol Cell
Title: Delta-Secretase Phosphorylation by SRPK2 Enhances Its Enzymatic Activity, Provoking Pathogenesis in Alzheimer's Disease.
Volume: 67
Issue: 5
Pages: 812-825.e5
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Publication
27605009 | J:353702
First Author: Qin Y
Year: 2016
Journal: J Immunol
Title: Stimulation of TLR4 Attenuates Alzheimer's Disease-Related Symptoms and Pathology in Tau-Transgenic Mice.
Volume: 197
Issue: 8
Pages: 3281-3292
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Publication
37117599 | J:339502
First Author: March-Diaz R
Year: 2021
Journal: Nat Aging
Title: Hypoxia compromises the mitochondrial metabolism of Alzheimer's disease microglia via HIF1.
Volume: 1
Issue: 4
Pages: 385-399
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Publication
31852801 | J:283511
 
First Author: Wheeler JM
Year: 2019
Journal: Sci Transl Med
Title: Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain.
Volume: 11
Issue: 523
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Publication
38526616 | J:347931
First Author: Edwards GA 3rd
Year: 2024
Journal: Acta Neuropathol
Title: TMEM106B coding variant is protective and deletion detrimental in a mouse model of tauopathy.
Volume: 147
Issue: 1
Pages: 61
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Publication
33891876 | J:306299
First Author: Bourdenx M
Year: 2021
Journal: Cell
Title: Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.
Volume: 184
Issue: 10
Pages: 2696-2714.e25
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Publication
31076275 | J:276144
First Author: Adaikkan C
Year: 2019
Journal: Neuron
Title: Gamma Entrainment Binds Higher-Order Brain Regions and Offers Neuroprotection.
Volume: 102
Issue: 5
Pages: 929-943.e8
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Publication
28814543 | J:250614
 
First Author: Le Pichon CE
Year: 2017
Journal: Sci Transl Med
Title: Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease.
Volume: 9
Issue: 403
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Publication
37315555 | J:339356
First Author: Sheehan PW
Year: 2023
Journal: Neuron
Title: An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology.
Volume: 111
Issue: 15
Pages: 2383-2398.e7
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Publication
37988169 | J:344400
 
First Author: Siew JJ
Year: 2024
Journal: J Clin Invest
Title: Galectin-3 aggravates microglial activation and tau transmission in tauopathy.
Volume: 134
Issue: 2
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Publication
37118504 | J:337860
First Author: Dejanovic B
Year: 2022
Journal: Nat Aging
Title: Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models.
Volume: 2
Issue: 9
Pages: 837-850
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Publication
36912451 | J:348477
 
First Author: Sai K
Year: 2023
Journal: J Cell Sci
Title: Aberrantly activated TAK1 links neuroinflammation and neuronal loss in Alzheimer's disease mouse models.
Volume: 136
Issue: 6
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Publication
35606145 | J:348877
First Author: Wang LH
Year: 2022
Journal: J Neurosci
Title: Calpain-2 Mediates MBNL2 Degradation and a Developmental RNA Processing Program in Neurodegeneration.
Volume: 42
Issue: 25
Pages: 5102-5114
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Publication
30879788 | J:352674
First Author: Martorell AJ
Year: 2019
Journal: Cell
Title: Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition.
Volume: 177
Issue: 2
Pages: 256-271.e22
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Genotype
Genotype
Symbol: Cx3cr1/Cx3cr1 Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/? Tg(Thy1-YFP)HJrs/?
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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