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Search results 2501 to 2600 out of 4141 for Mtor

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Hits by Strain

Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:7596429
Assay Type: Western blot
Annotation Date: 2024-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7596446
Age: embryonic day 18.5
Image: 7
Specimen Label: 9
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:6171120
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190113
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Depdc6
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6171120
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190113
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Depdc6
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6171120
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190113
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Depdc6
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6171120
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190113
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Depdc6
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6171120
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190113
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Depdc6
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6171120
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190113
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Depdc6
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6171120
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190113
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Depdc6
Detected: true
Specimen Num: 7
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Publication
34793600 | J:317363
First Author: Ruiz-Serrano A
Year: 2021
Journal: FASEB J
Title: OTUB1 regulates lung development, adult lung tissue homeostasis, and respiratory control.
Volume: 35
Issue: 12
Pages: e22039
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Publication
31729420 | J:287326
First Author: Malik N
Year: 2019
Journal: Sci Rep
Title: mTORC1 activity is essential for erythropoiesis and B cell lineage commitment.
Volume: 9
Issue: 1
Pages: 16917
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Protein
Q8CAT8
Organism: Mus musculus/domesticus
Length: 161  
Fragment?: false
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Protein
Q8CB99
Organism: Mus musculus/domesticus
Length: 216  
Fragment?: false
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Protein
Q8C2V9
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: false
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Protein
Q9D2K3
Organism: Mus musculus/domesticus
Length: 255  
Fragment?: false
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Publication
24991833 | -
First Author: Cottam EM
Year: 2014
Journal: Autophagy
Title: Coronavirus NSP6 restricts autophagosome expansion.
Volume: 10
Issue: 8
Pages: 1426-41
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Publication
21799305 | -
First Author: Cottam EM
Year: 2011
Journal: Autophagy
Title: Coronavirus nsp6 proteins generate autophagosomes from the endoplasmic reticulum via an omegasome intermediate.
Volume: 7
Issue: 11
Pages: 1335-47
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Publication
34381067 | J:309451
First Author: Vinsland E
Year: 2021
Journal: Sci Rep
Title: The zinc finger/RING domain protein Unkempt regulates cognitive flexibility.
Volume: 11
Issue: 1
Pages: 16299
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Publication
27501247 | J:236614
First Author: Cho SH
Year: 2016
Journal: Nature
Title: Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system.
Volume: 537
Issue: 7619
Pages: 234-238
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HT Experiment
GSE176171 | A single cell atlas of human adipose tissue
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Protein Coding Gene
MGI:87986 | Akt1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P31750
Organism: Mus musculus/domesticus
Length: 480  
Fragment?: false
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Publication
35361962 | J:337771
First Author: El-Saafin F
Year: 2022
Journal: Cell Death Differ
Title: Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death.
Volume: 29
Issue: 5
Pages: 1013-1027
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Publication
29127155 | J:259136
First Author: Woodford MR
Year: 2017
Journal: EMBO J
Title: Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.
Volume: 36
Issue: 24
Pages: 3650-3665
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Publication
19211835 | J:153377
First Author: Hosokawa N
Year: 2009
Journal: Mol Biol Cell
Title: Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.
Volume: 20
Issue: 7
Pages: 1981-91
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Publication
25438055 | J:268220
First Author: Cianfanelli V
Year: 2015
Journal: Nat Cell Biol
Title: AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation.
Volume: 17
Issue: 1
Pages: 20-30
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Publication
28473584 | J:243289
First Author: Ip WKE
Year: 2017
Journal: Science
Title: Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages.
Volume: 356
Issue: 6337
Pages: 513-519
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Publication
18054316 | J:130403
First Author: Zhao J
Year: 2007
Journal: Cell Metab
Title: FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells.
Volume: 6
Issue: 6
Pages: 472-83
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Publication
25402684 | J:217746
First Author: Bowman CJ
Year: 2014
Journal: Nat Cell Biol
Title: Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs.
Volume: 16
Issue: 12
Pages: 1202-14
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Publication
20399730 | J:160624
First Author: Kim S
Year: 2010
Journal: Neuron
Title: The apical complex couples cell fate and cell survival to cerebral cortical development.
Volume: 66
Issue: 1
Pages: 69-84
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Publication
32930093 | J:296018
   
First Author: Kumar A
Year: 2020
Journal: Elife
Title: SWELL1 regulates skeletal muscle cell size, intracellular signaling, adiposity and glucose metabolism.
Volume: 9
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Publication
25238095 | J:278429
First Author: Kobayashi T
Year: 2014
Journal: Immunity
Title: The histidine transporter SLC15A4 coordinates mTOR-dependent inflammatory responses and pathogenic antibody production.
Volume: 41
Issue: 3
Pages: 375-388
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Publication
25498145 | J:219629
First Author: McEwan DG
Year: 2015
Journal: Mol Cell
Title: PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins.
Volume: 57
Issue: 1
Pages: 39-54
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Publication
25060689 | J:228103
First Author: Cassano S
Year: 2014
Journal: Metabolism
Title: Leptin modulates autophagy in human CD4+CD25- conventional T cells.
Volume: 63
Issue: 10
Pages: 1272-9
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Publication
28314591 | J:259425
First Author: Whang MI
Year: 2017
Journal: Immunity
Title: The Ubiquitin Binding Protein TAX1BP1 Mediates Autophagasome Induction and the Metabolic Transition of Activated T Cells.
Volume: 46
Issue: 3
Pages: 405-420
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Publication
35675353 | J:326081
First Author: Donnard E
Year: 2022
Journal: PLoS Genet
Title: Single cell transcriptomics reveals dysregulated cellular and molecular networks in a fragile X syndrome model.
Volume: 18
Issue: 6
Pages: e1010221
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Publication
28235195 | J:239668
First Author: Cheng CW
Year: 2017
Journal: Cell
Title: Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes.
Volume: 168
Issue: 5
Pages: 775-788.e12
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Publication
32814046 | J:300273
First Author: Egozi A
Year: 2020
Journal: Cell Rep
Title: Zonation of Pancreatic Acinar Cells in Diabetic Mice.
Volume: 32
Issue: 7
Pages: 108043
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Publication
26166562 | J:224840
First Author: Solloway MJ
Year: 2015
Journal: Cell Rep
Title: Glucagon Couples Hepatic Amino Acid Catabolism to mTOR-Dependent Regulation of α-Cell Mass.
Volume: 12
Issue: 3
Pages: 495-510
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Publication
35082964 | J:322480
 
First Author: Wang S
Year: 2022
Journal: Oxid Med Cell Longev
Title: Activation of Transcription Factor EB Alleviates Tubular Epithelial Cell Injury via Restoring Lysosomal Homeostasis in Diabetic Nephropathy.
Volume: 2022
Pages: 2812493
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Publication
36198696 | J:329452
First Author: Sasako T
Year: 2022
Journal: Nat Commun
Title: Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice.
Volume: 13
Issue: 1
Pages: 5655
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Publication
16904612 | J:112705
First Author: Sodhi A
Year: 2006
Journal: Cancer Cell
Title: The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor.
Volume: 10
Issue: 2
Pages: 133-43
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Publication
31365870 | J:293384
First Author: Ohata H
Year: 2019
Journal: Cell Rep
Title: NOX1-Dependent mTORC1 Activation via S100A9 Oxidation in Cancer Stem-like Cells Leads to Colon Cancer Progression.
Volume: 28
Issue: 5
Pages: 1282-1295.e8
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Publication
28591638 | J:256739
First Author: Dean ED
Year: 2017
Journal: Cell Metab
Title: Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation.
Volume: 25
Issue: 6
Pages: 1362-1373.e5
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Publication
30926899 | J:273850
First Author: Niogret C
Year: 2019
Journal: Nat Commun
Title: Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells.
Volume: 10
Issue: 1
Pages: 1444
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Publication
18691549 | J:139572
First Author: Majumder PK
Year: 2008
Journal: Cancer Cell
Title: A prostatic intraepithelial neoplasia-dependent p27 Kip1 checkpoint induces senescence and inhibits cell proliferation and cancer progression.
Volume: 14
Issue: 2
Pages: 146-55
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Publication
22500629 | J:214509
First Author: Michalon A
Year: 2012
Journal: Neuron
Title: Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice.
Volume: 74
Issue: 1
Pages: 49-56
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Publication
26123588 | J:236514
 
First Author: Lepoutre-Lussey C
Year: 2016
Journal: Mol Cell Endocrinol
Title: From Nf1 to Sdhb knockout: Successes and failures in the quest for animal models of pheochromocytoma.
Volume: 421
Pages: 40-8
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Publication
32213345 | J:297232
First Author: Kurniawan H
Year: 2020
Journal: Cell Metab
Title: Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function.
Volume: 31
Issue: 5
Pages: 920-936.e7
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Publication
38849535 | J:356252
     
First Author: Ortega-Molina A
Year: 2024
Journal: Nat Aging
Title: A mild increase in nutrient signaling to mTORC1 in mice leads to parenchymal damage, myeloid inflammation and shortened lifespan.
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Publication
22608497 | J:187318
First Author: Park H
Year: 2012
Journal: Immunity
Title: Disruption of Fnip1 reveals a metabolic checkpoint controlling B lymphocyte development.
Volume: 36
Issue: 5
Pages: 769-81
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Publication
28555668 | J:249557
 
First Author: Lawless SJ
Year: 2017
Journal: Nat Commun
Title: Glucose represses dendritic cell-induced T cell responses.
Volume: 8
Pages: 15620
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Publication
25624444 | J:295375
First Author: Yang M
Year: 2015
Journal: J Exp Med
Title: PDK1 orchestrates early NK cell development through induction of E4BP4 expression and maintenance of IL-15 responsiveness.
Volume: 212
Issue: 2
Pages: 253-65
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Publication
25344724 | J:258672
First Author: Backer RA
Year: 2014
Journal: Nat Immunol
Title: A central role for Notch in effector CD8(+) T cell differentiation.
Volume: 15
Issue: 12
Pages: 1143-51
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Publication
31668641 | J:282413
First Author: Shi H
Year: 2019
Journal: Immunity
Title: Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb.
Volume: 51
Issue: 6
Pages: 1012-1027.e7
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Publication
32049019 | J:288068
First Author: Shin B
Year: 2020
Journal: Cell Rep
Title: Mitochondrial Oxidative Phosphorylation Regulates the Fate Decision between Pathogenic Th17 and Regulatory T Cells.
Volume: 30
Issue: 6
Pages: 1898-1909.e4
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Publication
24886239 | J:316460
 
First Author: Hamilton A
Year: 2014
Journal: Mol Brain
Title: Metabotropic glutamate receptor 5 knockout reduces cognitive impairment and pathogenesis in a mouse model of Alzheimer's disease.
Volume: 7
Pages: 40
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Publication
30078553 | J:269111
First Author: Kong X
Year: 2018
Journal: Cell Metab
Title: Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin.
Volume: 28
Issue: 4
Pages: 631-643.e3
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Publication
25362851 | J:224256
First Author: Xu Y
Year: 2015
Journal: Oncogene
Title: Manganese superoxide dismutase deficiency triggers mitochondrial uncoupling and the Warburg effect.
Volume: 34
Issue: 32
Pages: 4229-37
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Publication
26110849 | J:233794
First Author: Zhou JX
Year: 2015
Journal: PLoS One
Title: TNFα signaling regulates cystic epithelial cell proliferation through Akt/mTOR and ERK/MAPK/Cdk2 mediated Id2 signaling.
Volume: 10
Issue: 6
Pages: e0131043
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Publication
30412050 | J:272206
   
First Author: Riahi Y
Year: 2018
Journal: Elife
Title: Inhibition of mTORC1 by ER stress impairs neonatal β-cell expansion and predisposes to diabetes in the Akita mouse.
Volume: 7
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Publication
24206664 | J:206172
First Author: Morita M
Year: 2013
Journal: Cell Metab
Title: mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation.
Volume: 18
Issue: 5
Pages: 698-711
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Publication
21962509 | J:177113
First Author: Zhu H
Year: 2011
Journal: Cell
Title: The Lin28/let-7 axis regulates glucose metabolism.
Volume: 147
Issue: 1
Pages: 81-94
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Publication
33899734 | J:306384
   
First Author: Terrey M
Year: 2021
Journal: Elife
Title: Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology.
Volume: 10
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Publication
25233189 | J:225344
 
First Author: Missios P
Year: 2014
Journal: Nat Commun
Title: Glucose substitution prolongs maintenance of energy homeostasis and lifespan of telomere dysfunctional mice.
Volume: 5
Pages: 4924
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Publication
31053533 | J:289647
First Author: Liang S
Year: 2019
Journal: Cell Host Microbe
Title: Nutrient Sensing by the Intestinal Epithelium Orchestrates Mucosal Antimicrobial Defense via Translational Control of Hes1.
Volume: 25
Issue: 5
Pages: 706-718.e7
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Publication
28746872 | J:271480
First Author: Lipton JO
Year: 2017
Journal: Cell Rep
Title: Aberrant Proteostasis of BMAL1 Underlies Circadian Abnormalities in a Paradigmatic mTOR-opathy.
Volume: 20
Issue: 4
Pages: 868-880
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Publication
25155956 | J:217829
First Author: Tang G
Year: 2014
Journal: Neuron
Title: Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits.
Volume: 83
Issue: 5
Pages: 1131-43
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Publication
20062052 | J:156683
First Author: Nie D
Year: 2010
Journal: Nat Neurosci
Title: Tsc2-Rheb signaling regulates EphA-mediated axon guidance.
Volume: 13
Issue: 2
Pages: 163-72
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Publication
24077282 | J:214354
First Author: Wang F
Year: 2014
Journal: Oncogene
Title: Pivotal role of augmented αB-crystallin in tumor development induced by deficient TSC1/2 complex.
Volume: 33
Issue: 34
Pages: 4352-8
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Publication
26913956 | J:269707
 
First Author: Ro SH
Year: 2016
Journal: Elife
Title: Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis.
Volume: 5
Pages: e12204
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Publication
32514619 | J:298320
First Author: Zheng M
Year: 2020
Journal: Cancer Immunol Immunother
Title: ADRB3 expression in tumor cells is a poor prognostic factor and promotes proliferation in non-small cell lung carcinoma.
Volume: 69
Issue: 11
Pages: 2345-2355
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Publication
28347403 | J:244871
   
First Author: Tomasoni R
Year: 2017
Journal: Elife
Title: Lack of IL-1R8 in neurons causes hyperactivation of IL-1 receptor pathway and induces MECP2-dependent synaptic defects.
Volume: 6
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Publication
23892607 | J:205308
First Author: Ma M
Year: 2013
Journal: Nat Genet
Title: Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease.
Volume: 45
Issue: 9
Pages: 1004-12
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Publication
28100467 | J:245033
First Author: Mohapatra B
Year: 2017
Journal: Development
Title: An essential role of CBL and CBL-B ubiquitin ligases in mammary stem cell maintenance.
Volume: 144
Issue: 6
Pages: 1072-1086
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Publication
19261747 | J:146760
First Author: Puzio-Kuter AM
Year: 2009
Journal: Genes Dev
Title: Inactivation of p53 and Pten promotes invasive bladder cancer.
Volume: 23
Issue: 6
Pages: 675-80
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Publication
31328154 | J:293620
First Author: Radu AG
Year: 2019
Journal: Sci Adv
Title: LKB1 specifies neural crest cell fates through pyruvate-alanine cycling.
Volume: 5
Issue: 7
Pages: eaau5106
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Publication
23361300 | J:196881
First Author: Khalaileh A
Year: 2013
Journal: Cancer Res
Title: Phosphorylation of ribosomal protein S6 attenuates DNA damage and tumor suppression during development of pancreatic cancer.
Volume: 73
Issue: 6
Pages: 1811-20
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Publication
23263555 | J:192613
First Author: Strainic MG
Year: 2013
Journal: Nat Immunol
Title: Absence of signaling into CD4⁺ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3⁺ regulatory T cells.
Volume: 14
Issue: 2
Pages: 162-71
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Publication
25730472 | J:274440
First Author: Fu NY
Year: 2015
Journal: Nat Cell Biol
Title: EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival.
Volume: 17
Issue: 4
Pages: 365-75
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Publication
26573296 | J:229018
First Author: Xia P
Year: 2015
Journal: J Exp Med
Title: Insulin-InsR signaling drives multipotent progenitor differentiation toward lymphoid lineages.
Volume: 212
Issue: 13
Pages: 2305-21
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Publication
22153375 | J:178913
First Author: Wang CC
Year: 2011
Journal: Neuron
Title: A critical role for GluN2B-containing NMDA receptors in cortical development and function.
Volume: 72
Issue: 5
Pages: 789-805
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Publication
33758188 | J:303833
First Author: Fujino T
Year: 2021
Journal: Nat Commun
Title: Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway.
Volume: 12
Issue: 1
Pages: 1826
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Publication
29763624 | J:261866
First Author: Momcilovic M
Year: 2018
Journal: Cancer Cell
Title: The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma.
Volume: 33
Issue: 5
Pages: 905-921.e5
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Publication
29745900 | J:356060
   
First Author: Chau KF
Year: 2018
Journal: Elife
Title: Downregulation of ribosome biogenesis during early forebrain development.
Volume: 7
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Publication
31089135 | J:275571
First Author: Liu J
Year: 2019
Journal: Nat Commun
Title: JNK1/2 represses Lkb1-deficiency-induced lung squamous cell carcinoma progression.
Volume: 10
Issue: 1
Pages: 2148
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Publication
25584893 | J:218894
First Author: Damsky W
Year: 2015
Journal: Cancer Cell
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