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Search results 2501 to 2600 out of 3113 for Rac1

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Hits by Pathway

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Hits by Strain

Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:6185137
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191477
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Tiam1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6185137
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191477
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Tiam1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6185137
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191477
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Tiam1
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:2662993
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1796222
Stage: TS22
Assay Id: MGI:2666222
Age: embryonic day 14.5
Image: Tiam1 14.5dpc
Specimen Label: Tiam1 14.5dpc
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:2662995
Assay Type: RNA in situ
Annotation Date: 2003-07-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1796222
Stage: TS22
Assay Id: MGI:2666223
Age: embryonic day 14.5
Image: Tiam1 14.5dpc
Specimen Label: Tiam1 14.5dpc
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5001661
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5542215
Age: embryonic day 15.5
Image: GUDMAP:8443
Specimen Label: GUDMAP:8443
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4422222
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828714
Age: embryonic day 14.5
Image: euxassay_006321_12
Specimen Label: euxassay_006321_12
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:4422222
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828714
Age: embryonic day 14.5
Image: euxassay_006321_16
Specimen Label: euxassay_006321_16
Detected: true
Specimen Num: 16
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Publication
- | J:200814
     
First Author: Toronto Centre for Phenogenomics
Year: 2013
Journal: MGI Direct Data Submission
Title: Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051).
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Protein Coding Gene
MGI:1924307 | Ston1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:107929 | Pip5k1a
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1914634 | Bag4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2153093 | Cspg4
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
23453624 | J:197054
First Author: Eser S
Year: 2013
Journal: Cancer Cell
Title: Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer.
Volume: 23
Issue: 3
Pages: 406-20
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Publication
19879843 | J:157297
First Author: Srinivasan L
Year: 2009
Journal: Cell
Title: PI3 kinase signals BCR-dependent mature B cell survival.
Volume: 139
Issue: 3
Pages: 573-86
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Protein Coding Gene
MGI:1098772 | Pik3r2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P63001
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: false
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Protein
O08908
Organism: Mus musculus/domesticus
Length: 722  
Fragment?: false
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Protein
Q61223
Organism: Mus musculus/domesticus
Length: 46  
Fragment?: true
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Protein
A0A2I3BRJ9
Organism: Mus musculus/domesticus
Length: 177  
Fragment?: true
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Publication
9428629 | J:44758
First Author: Haffner C
Year: 1997
Journal: FEBS Lett
Title: Synaptojanin 1: localization on coated endocytic intermediates in nerve terminals and interaction of its 170 kDa isoform with Eps15.
Volume: 419
Issue: 2-3
Pages: 175-80
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Publication
10542231 | -
First Author: Cestra G
Year: 1999
Journal: J Biol Chem
Title: The SH3 domains of endophilin and amphiphysin bind to the proline-rich region of synaptojanin 1 at distinct sites that display an unconventional binding specificity.
Volume: 274
Issue: 45
Pages: 32001-7
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Publication
21932368 | -
First Author: Takaichi R
Year: 2012
Journal: J Neurosci Res
Title: Inhibitory effect of NAP-22 on the phosphatase activity of synaptojanin-1.
Volume: 90
Issue: 1
Pages: 21-7
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Publication
21316588 | -
First Author: Chang-Ileto B
Year: 2011
Journal: Dev Cell
Title: Synaptojanin 1-mediated PI(4,5)P2 hydrolysis is modulated by membrane curvature and facilitates membrane fission.
Volume: 20
Issue: 2
Pages: 206-18
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Protein
Q3V1U8
Organism: Mus musculus/domesticus
Length: 326  
Fragment?: false
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Protein
Q8BGF6
Organism: Mus musculus/domesticus
Length: 293  
Fragment?: false
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Protein
Q91YP6
Organism: Mus musculus/domesticus
Length: 381  
Fragment?: false
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Protein
P84096
Organism: Mus musculus/domesticus
Length: 191  
Fragment?: false
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Protein
Q3UDZ1
Organism: Mus musculus/domesticus
Length: 191  
Fragment?: false
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Protein
Q8C8B2
Organism: Mus musculus/domesticus
Length: 294  
Fragment?: false
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Protein
Q3TPW1
Organism: Mus musculus/domesticus
Length: 164  
Fragment?: true
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Protein
H3BK10
Organism: Mus musculus/domesticus
Length: 167  
Fragment?: true
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Protein
Q8BHN8
Organism: Mus musculus/domesticus
Length: 216  
Fragment?: false
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Protein
B7ZN22
Organism: Mus musculus/domesticus
Length: 269  
Fragment?: false
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Protein
B7ZN20
Organism: Mus musculus/domesticus
Length: 295  
Fragment?: true
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Protein
H3BIZ5
Organism: Mus musculus/domesticus
Length: 174  
Fragment?: true
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Protein
Z4YMR3
Organism: Mus musculus/domesticus
Length: 262  
Fragment?: true
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Protein
A0A0U1RPA9
Organism: Mus musculus/domesticus
Length: 213  
Fragment?: true
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Protein
E9Q0K9
Organism: Mus musculus/domesticus
Length: 326  
Fragment?: false
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Protein
Q0P556
Organism: Mus musculus/domesticus
Length: 295  
Fragment?: true
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Protein
H3BIW1
Organism: Mus musculus/domesticus
Length: 181  
Fragment?: true
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Protein
A0A1B0GS53
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: true
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Protein
A0A1B0GRZ8
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: true
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Protein
Q3TMS1
Organism: Mus musculus/domesticus
Length: 295  
Fragment?: false
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Protein
H3BL29
Organism: Mus musculus/domesticus
Length: 188  
Fragment?: true
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Protein
E9Q4H6
Organism: Mus musculus/domesticus
Length: 57  
Fragment?: true
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Protein
Q8BHP4
Organism: Mus musculus/domesticus
Length: 164  
Fragment?: false
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Protein
A2ALX7
Organism: Mus musculus/domesticus
Length: 385  
Fragment?: false
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Protein
A2ALX6
Organism: Mus musculus/domesticus
Length: 294  
Fragment?: false
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Protein
Q6P9S0
Organism: Mus musculus/domesticus
Length: 715  
Fragment?: false
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Protein
F6S054
Organism: Mus musculus/domesticus
Length: 289  
Fragment?: true
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Protein
F7D291
Organism: Mus musculus/domesticus
Length: 364  
Fragment?: true
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Protein
D3YWC9
Organism: Mus musculus/domesticus
Length: 653  
Fragment?: false
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Publication
21093245 | -
First Author: Zhao H
Year: 2011
Journal: Curr Opin Cell Biol
Title: I-BAR domain proteins: linking actin and plasma membrane dynamics.
Volume: 23
Issue: 1
Pages: 14-21
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Publication
11058585 | J:114700
First Author: van Horck FP
Year: 2001
Journal: J Biol Chem
Title: Characterization of p190RhoGEF, a RhoA-specific guanine nucleotide exchange factor that interacts with microtubules.
Volume: 276
Issue: 7
Pages: 4948-56
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Publication
23595754 | J:196966
First Author: Duman JG
Year: 2013
Journal: J Neurosci
Title: The adhesion-GPCR BAI1 regulates synaptogenesis by controlling the recruitment of the Par3/Tiam1 polarity complex to synaptic sites.
Volume: 33
Issue: 16
Pages: 6964-78
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Publication
23628982 | J:222140
First Author: Lanoue V
Year: 2013
Journal: Mol Psychiatry
Title: The adhesion-GPCR BAI3, a gene linked to psychiatric disorders, regulates dendrite morphogenesis in neurons.
Volume: 18
Issue: 8
Pages: 943-50
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Publication
15546919 | J:94300
First Author: I ST
Year: 2004
Journal: J Cell Sci
Title: ARAP3 is transiently tyrosine phosphorylated in cells attaching to fibronectin and inhibits cell spreading in a RhoGAP-dependent manner.
Volume: 117
Issue: Pt 25
Pages: 6071-84
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Publication
24297929 | J:205503
First Author: Fiuza M
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: GluN3A expression restricts spine maturation via inhibition of GIT1/Rac1 signaling.
Volume: 110
Issue: 51
Pages: 20807-12
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Publication
26969129 | J:238439
 
First Author: Sarowar T
Year: 2016
Journal: Mol Brain
Title: Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2.
Volume: 9
Pages: 28
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Publication
14765121 | J:88449
First Author: Steffen A
Year: 2004
Journal: EMBO J
Title: Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation.
Volume: 23
Issue: 4
Pages: 749-59
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Publication
19153220 | J:146157
First Author: Mao YS
Year: 2009
Journal: J Cell Biol
Title: Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis.
Volume: 184
Issue: 2
Pages: 281-96
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Publication
21984824 | J:354166
First Author: Tortosa E
Year: 2011
Journal: J Biol Chem
Title: Microtubule-associated protein 1B (MAP1B) is required for dendritic spine development and synaptic maturation.
Volume: 286
Issue: 47
Pages: 40638-48
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Publication
15345511 | J:103925
First Author: Sakata Y
Year: 2004
Journal: Arterioscler Thromb Vasc Biol
Title: Transcription factor CHF1/Hey2 regulates neointimal formation in vivo and vascular smooth muscle proliferation and migration in vitro.
Volume: 24
Issue: 11
Pages: 2069-74
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Publication
11744688 | J:74670
First Author: Jenna S
Year: 2002
Journal: J Biol Chem
Title: The activity of the GTPase-activating protein CdGAP is regulated by the endocytic protein intersectin.
Volume: 277
Issue: 8
Pages: 6366-73
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Publication
20702777 | J:166376
First Author: Takegahara N
Year: 2010
Journal: FASEB J
Title: Integral roles of a guanine nucleotide exchange factor, FARP2, in osteoclast podosome rearrangements.
Volume: 24
Issue: 12
Pages: 4782-92
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Publication
27328625 | J:241464
 
First Author: Kim B
Year: 2016
Journal: Sci Rep
Title: Roles of the mitochondrial Na(+)-Ca(2+) exchanger, NCLX, in B lymphocyte chemotaxis.
Volume: 6
Pages: 28378
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Publication
17698736 | J:139849
First Author: Matsui A
Year: 2007
Journal: Circulation
Title: Central role of calcium-dependent tyrosine kinase PYK2 in endothelial nitric oxide synthase-mediated angiogenic response and vascular function.
Volume: 116
Issue: 9
Pages: 1041-51
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Publication
16782872 | J:110334
First Author: Hunter SG
Year: 2006
Journal: Mol Cell Biol
Title: Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis.
Volume: 26
Issue: 13
Pages: 4830-42
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Publication
18387945 | J:137566
First Author: Fang WB
Year: 2008
Journal: J Biol Chem
Title: Identification and functional analysis of phosphorylated tyrosine residues within EphA2 receptor tyrosine kinase.
Volume: 283
Issue: 23
Pages: 16017-26
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Publication
17537723 | J:124615
First Author: Kreis P
Year: 2007
Journal: J Biol Chem
Title: The p21-activated kinase 3 implicated in mental retardation regulates spine morphogenesis through a Cdc42-dependent pathway.
Volume: 282
Issue: 29
Pages: 21497-506
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Publication
21820096 | J:189271
First Author: Shaheen R
Year: 2011
Journal: Am J Hum Genet
Title: Recessive mutations in DOCK6, encoding the guanidine nucleotide exchange factor DOCK6, lead to abnormal actin cytoskeleton organization and Adams-Oliver syndrome.
Volume: 89
Issue: 2
Pages: 328-33
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Publication
8939998 | J:36812
First Author: Zalcman G
Year: 1996
Journal: J Biol Chem
Title: RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG.
Volume: 271
Issue: 48
Pages: 30366-74
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Publication
12547822 | J:82956
First Author: Guo X
Year: 2003
Journal: J Biol Chem
Title: A Rac/Cdc42-specific exchange factor, GEFT, induces cell proliferation, transformation, and migration.
Volume: 278
Issue: 15
Pages: 13207-15
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Publication
18541910 | J:161106
First Author: Smith TK
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Bves directly interacts with GEFT, and controls cell shape and movement through regulation of Rac1/Cdc42 activity.
Volume: 105
Issue: 24
Pages: 8298-303
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Publication
19897731 | J:154749
First Author: Quinn BJ
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Erythrocyte scaffolding protein p55/MPP1 functions as an essential regulator of neutrophil polarity.
Volume: 106
Issue: 47
Pages: 19842-7
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Publication
8662891 | J:33389
First Author: Reid T
Year: 1996
Journal: J Biol Chem
Title: Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain.
Volume: 271
Issue: 23
Pages: 13556-60
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Publication
12819203 | J:85269
First Author: Zhao C
Year: 2003
Journal: J Biol Chem
Title: GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2.
Volume: 278
Issue: 36
Pages: 34641-53
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Publication
12454018 | J:81674
First Author: Moon SY
Year: 2003
Journal: J Biol Chem
Title: Characterization of a brain-specific Rho GTPase-activating protein, p200RhoGAP.
Volume: 278
Issue: 6
Pages: 4151-9
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Publication
10967094 | J:65771
First Author: Vignal E
Year: 2000
Journal: J Biol Chem
Title: Characterization of TCL, a new GTPase of the rho family related to TC10 andCcdc42.
Volume: 275
Issue: 46
Pages: 36457-64
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Publication
16243036 | J:102213
First Author: Dong X
Year: 2005
Journal: Curr Biol
Title: P-Rex1 is a primary Rac2 guanine nucleotide exchange factor in mouse neutrophils.
Volume: 15
Issue: 20
Pages: 1874-9
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Publication
10669753 | J:60268
First Author: Vartiainen M
Year: 2000
Journal: Mol Cell Biol
Title: Mouse A6/twinfilin is an actin monomer-binding protein that localizes to the regions of rapid actin dynamics.
Volume: 20
Issue: 5
Pages: 1772-83
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Publication
31685899 | J:287299
First Author: Palese F
Year: 2019
Journal: Sci Rep
Title: A protective role for N-acylphosphatidylethanolamine phospholipase D in 6-OHDA-induced neurodegeneration.
Volume: 9
Issue: 1
Pages: 15927
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Publication
13679059 | J:85986
First Author: Komai K
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Characterization of novel splicing variants of the mouse MCF-2 (DBL) proto-oncogene.
Volume: 309
Issue: 4
Pages: 906-9
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Publication
22349825 | J:244534
First Author: Kikuchi K
Year: 2013
Journal: Oncogene
Title: Protein kinase C iota as a therapeutic target in alveolar rhabdomyosarcoma.
Volume: 32
Issue: 3
Pages: 286-95
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Publication
23383154 | J:195783
First Author: Ali WH
Year: 2013
Journal: PLoS One
Title: Deficiencies of the lipid-signaling enzymes phospholipase D1 and D2 alter cytoskeletal organization, macrophage phagocytosis, and cytokine-stimulated neutrophil recruitment.
Volume: 8
Issue: 1
Pages: e55325
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Publication
16873721 | J:125071
First Author: Ikeda K
Year: 2006
Journal: Circ Res
Title: Glia maturation factor-gamma is preferentially expressed in microvascular endothelial and inflammatory cells and modulates actin cytoskeleton reorganization.
Volume: 99
Issue: 4
Pages: 424-33
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Publication
21989057 | J:179026
First Author: Ramakers GJ
Year: 2012
Journal: Hum Mol Genet
Title: Dysregulation of Rho GTPases in the αPix/Arhgef6 mouse model of X-linked intellectual disability is paralleled by impaired structural and synaptic plasticity and cognitive deficits.
Volume: 21
Issue: 2
Pages: 268-86
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Publication
21098092 | J:176870
First Author: Wen H
Year: 2010
Journal: J Exp Med
Title: Plexin-A4-semaphorin 3A signaling is required for Toll-like receptor- and sepsis-induced cytokine storm.
Volume: 207
Issue: 13
Pages: 2943-57
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Publication
24333420 | J:211863
First Author: Ko SH
Year: 2014
Journal: Biochem Biophys Res Commun
Title: 8-Oxo-2'-deoxyguanosine ameliorates features of metabolic syndrome in obese mice.
Volume: 443
Issue: 2
Pages: 610-6
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Publication
27655131 | J:237852
First Author: Cheerathodi M
Year: 2016
Journal: Mol Cancer Res
Title: The Cytoskeletal Adapter Protein Spinophilin Regulates Invadopodia Dynamics and Tumor Cell Invasion in Glioblastoma.
Volume: 14
Issue: 12
Pages: 1277-1287
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Publication
29985166 | J:264704
First Author: Maeda K
Year: 2018
Journal: J Clin Invest
Title: CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease.
Volume: 128
Issue: 8
Pages: 3445-3459
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Publication
22128240 | J:179662
 
First Author: Heynen SR
Year: 2011
Journal: Mol Vis
Title: Retinal degeneration modulates intracellular localization of CDC42 in photoreceptors.
Volume: 17
Pages: 2934-46
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Publication
26224570 | J:258556
First Author: Madrigal-Matute J
Year: 2015
Journal: Cardiovasc Res
Title: TWEAK/Fn14 interaction promotes oxidative stress through NADPH oxidase activation in macrophages.
Volume: 108
Issue: 1
Pages: 139-47
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Publication
15692095 | J:110022
First Author: Laufs U
Year: 2005
Journal: Arterioscler Thromb Vasc Biol
Title: Physical inactivity increases oxidative stress, endothelial dysfunction, and atherosclerosis.
Volume: 25
Issue: 4
Pages: 809-14
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Publication
27634010 | J:240513
First Author: Schierwagen R
Year: 2016
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Statins improve NASH via inhibition of RhoA and Ras.
Volume: 311
Issue: 4
Pages: G724-G733
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Publication
37255534 | J:346322
 
First Author: Carbonell AU
Year: 2023
Journal: Front Aging Neurosci
Title: Comparing synaptic proteomes across five mouse models for autism reveals converging molecular similarities including deficits in oxidative phosphorylation and Rho GTPase signaling.
Volume: 15
Pages: 1152562
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Publication
23334894 | J:210275
First Author: Khan OM
Year: 2013
Journal: Circulation
Title: Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice.
Volume: 127
Issue: 7
Pages: 782-90
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27525442 | J:237240
First Author: Miyazaki T
Year: 2016
Journal: J Clin Invest
Title: Calpain-6 confers atherogenicity to macrophages by dysregulating pre-mRNA splicing.
Volume: 126
Issue: 9
Pages: 3417-32
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26705735 | J:231931
 
First Author: Orefice LL
Year: 2016
Journal: Mol Cell Neurosci
Title: Control of spine maturation and pruning through proBDNF synthesized and released in dendrites.
Volume: 71
Pages: 66-79
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