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Search results 2501 to 2600 out of 5471 for Tyr

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Type Details Score
Publication
32321760 | J:293245
First Author: Corliss BA
Year: 2020
Journal: Diabetes
Title: Pericyte Bridges in Homeostasis and Hyperglycemia.
Volume: 69
Issue: 7
Pages: 1503-1517
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Publication
37562406 | J:358369
First Author: Ji X
Year: 2023
Journal: Cell Chem Biol
Title: Genetic activation of glycolysis in osteoblasts preserves bone mass in type I diabetes.
Volume: 30
Issue: 9
Pages: 1053-1063.e5
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Publication
31217360 | J:290189
 
First Author: Kakoki M
Year: 2019
Journal: JCI Insight
Title: Engulfment and cell motility protein 1 potentiates diabetic cardiomyopathy via Rac-dependent and Rac-independent ROS production.
Volume: 4
Issue: 12
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Publication
28490532 | J:263915
First Author: Wang L
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: Podocyte-specific knockout of cyclooxygenase 2 exacerbates diabetic kidney disease.
Volume: 313
Issue: 2
Pages: F430-F439
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Publication
35608871 | J:330885
First Author: Li K
Year: 2022
Journal: FASEB J
Title: Impaired glucose metabolism underlies articular cartilage degeneration in osteoarthritis.
Volume: 36
Issue: 6
Pages: e22377
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Publication
32726619 | J:314400
First Author: Kogot-Levin A
Year: 2020
Journal: Cell Rep
Title: Proximal Tubule mTORC1 Is a Central Player in the Pathophysiology of Diabetic Nephropathy and Its Correction by SGLT2 Inhibitors.
Volume: 32
Issue: 4
Pages: 107954
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Publication
25705882 | J:221902
First Author: Kwong LN
Year: 2015
Journal: J Clin Invest
Title: Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma.
Volume: 125
Issue: 4
Pages: 1459-70
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Publication
26206884 | J:329611
First Author: Fufa TD
Year: 2015
Journal: Hum Mol Genet
Title: Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes.
Volume: 24
Issue: 19
Pages: 5433-50
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Publication
20048081 | J:155731
First Author: Held MA
Year: 2010
Journal: Cancer Res
Title: Characterization of melanoma cells capable of propagating tumors from a single cell.
Volume: 70
Issue: 1
Pages: 388-97
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Publication
18006687 | J:127315
First Author: Delmas V
Year: 2007
Journal: Genes Dev
Title: Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development.
Volume: 21
Issue: 22
Pages: 2923-35
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Publication
30355677 | J:271155
First Author: Hill KS
Year: 2019
Journal: Mol Cancer Res
Title: PTPN11 Plays Oncogenic Roles and Is a Therapeutic Target for BRAF Wild-Type Melanomas.
Volume: 17
Issue: 2
Pages: 583-593
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Publication
35311644 | J:349119
   
First Author: Reinitz F
Year: 2022
Journal: Elife
Title: Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer's model.
Volume: 11
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Publication
32238882 | J:335346
First Author: Uka R
Year: 2020
Journal: Oncogene
Title: Temporal activation of WNT/β-catenin signaling is sufficient to inhibit SOX10 expression and block melanoma growth.
Volume: 39
Issue: 20
Pages: 4132-4154
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Publication
22698401 | J:189285
First Author: Liu W
Year: 2012
Journal: Cancer Cell
Title: LKB1/STK11 inactivation leads to expansion of a prometastatic tumor subpopulation in melanoma.
Volume: 21
Issue: 6
Pages: 751-64
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Publication
28368416 | J:247693
First Author: Schaefer SM
Year: 2017
Journal: Oncogene
Title: Sox2 is dispensable for primary melanoma and metastasis formation.
Volume: 36
Issue: 31
Pages: 4516-4524
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Publication
25609585 | J:219707
 
First Author: Zingg D
Year: 2015
Journal: Nat Commun
Title: The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors.
Volume: 6
Pages: 6051
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Publication
26450788 | J:231490
First Author: Rai K
Year: 2015
Journal: Cancer Discov
Title: Dual Roles of RNF2 in Melanoma Progression.
Volume: 5
Issue: 12
Pages: 1314-27
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Strain
MGI:6792067 | STOCK Tg(Tyr-cre/ERT2)13Bos Gt(ROSA)26Sor<tm1(GNAQ*)Cvrk>/Gt(ROSA)26Sor<tm1Sor>/Cvrk
Attribute String: mutant stock, targeted mutation, transgenic
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Publication
23935512 | J:213046
First Author: Harris ML
Year: 2013
Journal: PLoS Genet
Title: A dual role for SOX10 in the maintenance of the postnatal melanocyte lineage and the differentiation of melanocyte stem cell progenitors.
Volume: 9
Issue: 7
Pages: e1003644
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Publication
26113083 | J:225597
First Author: Huang JL
Year: 2015
Journal: Cancer Res
Title: Oncogenic G Protein GNAQ Induces Uveal Melanoma and Intravasation in Mice.
Volume: 75
Issue: 16
Pages: 3384-97
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Publication
25584893 | J:218894
First Author: Damsky W
Year: 2015
Journal: Cancer Cell
Title: mTORC1 activation blocks BrafV600E-induced growth arrest but is insufficient for melanoma formation.
Volume: 27
Issue: 1
Pages: 41-56
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Publication
28192409 | J:243383
First Author: Tonks ID
Year: 2017
Journal: Oncogene
Title: Melanocyte transformation requires complete loss of all pocket protein function via a mechanism that mitigates the need for MAPK pathway activation.
Volume: 36
Issue: 26
Pages: 3789-3795
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Publication
29438700 | J:257785
First Author: Yu Y
Year: 2018
Journal: Cancer Cell
Title: Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.
Volume: 33
Issue: 2
Pages: 322-336.e8
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Strain
MGI:4948437 | B6.Cg-Tg(Tyr-cre/ERT2)13Bos Braf<tm1Mmcm> Pten<tm1Hwu>/BosJ
Attribute String: transgenic, targeted mutation, mutant strain, congenic
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Publication
34689087 | J:312866
 
First Author: Le HH
Year: 2021
Journal: EBioMedicine
Title: Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells.
Volume: 73
Pages: 103646
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Publication
28376192 | J:245620
 
First Author: Bonet C
Year: 2017
Journal: J Natl Cancer Inst
Title: Deciphering the Role of Oncogenic MITFE318K in Senescence Delay and Melanoma Progression.
Volume: 109
Issue: 8
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Publication
31449725 | J:309201
First Author: Zhai Y
Year: 2020
Journal: Pigment Cell Melanoma Res
Title: Differences in tumor initiation and progression of melanoma in the BrafCA ;Tyr-CreERT2;Ptenf/f model between male and female mice.
Volume: 33
Issue: 1
Pages: 119-121
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Publication
30209062 | J:286512
First Author: Zhao F
Year: 2018
Journal: Cancer Immunol Res
Title: Stromal Fibroblasts Mediate Anti-PD-1 Resistance via MMP-9 and Dictate TGFβ Inhibitor Sequencing in Melanoma.
Volume: 6
Issue: 12
Pages: 1459-1471
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Publication
34597611 | J:333928
First Author: Chhabra G
Year: 2022
Journal: J Invest Dermatol
Title: Antimelanoma Effects of Concomitant Inhibition of SIRT1 and SIRT3 in Braf(V600E)/Pten(NULL) Mice.
Volume: 142
Issue: 4
Pages: 1145-1157.e7
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Publication
32620791 | J:293364
First Author: Ishak Gabra MB
Year: 2020
Journal: Nat Commun
Title: Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth.
Volume: 11
Issue: 1
Pages: 3326
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Publication
29179997 | J:253811
 
First Author: Rodríguez CI
Year: 2018
Journal: Cancer Lett
Title: Elevated cyclic AMP levels promote BRAFCA/Pten-/- mouse melanoma growth but pCREB is negatively correlated with human melanoma progression.
Volume: 414
Pages: 268-277
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Publication
28111070 | J:239513
First Author: Spitzer MH
Year: 2017
Journal: Cell
Title: Systemic Immunity Is Required for Effective Cancer Immunotherapy.
Volume: 168
Issue: 3
Pages: 487-502.e15
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Publication
38640236 | J:348259
First Author: Niu L
Year: 2024
Journal: Sci Adv
Title: Noncovalently particle-anchored cytokines with prolonged tumor retention safely elicit potent antitumor immunity.
Volume: 10
Issue: 16
Pages: eadk7695
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Publication
26679841 | J:227690
First Author: Ferretti R
Year: 2016
Journal: Genes Dev
Title: BMI1 induces an invasive signature in melanoma that promotes metastasis and chemoresistance.
Volume: 30
Issue: 1
Pages: 18-33
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Publication
28851815 | J:249476
First Author: Rodríguez CI
Year: 2017
Journal: Mol Cancer Res
Title: EPAC-RAP1 Axis-Mediated Switch in the Response of Primary and Metastatic Melanoma to Cyclic AMP.
Volume: 15
Issue: 12
Pages: 1792-1802
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Publication
36672468 | J:332804
 
First Author: Mikheil D
Year: 2023
Journal: Cancers (Basel)
Title: Notch Signaling Suppresses Melanoma Tumor Development in BRAF/Pten Mice.
Volume: 15
Issue: 2
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Publication
35385746 | J:328646
First Author: Jahid S
Year: 2022
Journal: Cell Rep
Title: Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer.
Volume: 39
Issue: 1
Pages: 110641
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Publication
30664687 | J:295160
First Author: Bagati A
Year: 2019
Journal: Oncogene
Title: KLF9-dependent ROS regulate melanoma progression in stage-specific manner.
Volume: 38
Issue: 19
Pages: 3585-3597
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Publication
29643229 | J:352709
 
First Author: Neubert NJ
Year: 2018
Journal: Sci Transl Med
Title: T cell-induced CSF1 promotes melanoma resistance to PD1 blockade.
Volume: 10
Issue: 436
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Publication
23563312 | J:201460
First Author: Hanna SC
Year: 2013
Journal: J Clin Invest
Title: HIF1α and HIF2α independently activate SRC to promote melanoma metastases.
Volume: 123
Issue: 5
Pages: 2078-93
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Publication
35561684 | J:325979
First Author: Choi YS
Year: 2022
Journal: Cell
Title: Topical therapy for regression and melanoma prevention of congenital giant nevi.
Volume: 185
Issue: 12
Pages: 2071-2085.e12
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Strain
MGI:5752238 | B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Nras<tm1.1Nesh> Cdkn2a<tm2.1Nesh> Stk11<tm1.1Rdp>
Attribute String: transgenic, targeted mutation, mutant strain, congenic
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Publication
24003131 | J:201160
First Author: Ni TK
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Low-copy piggyBac transposon mutagenesis in mice identifies genes driving melanoma.
Volume: 110
Issue: 38
Pages: E3640-9
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Publication
35768444 | J:326521
First Author: Vittoria MA
Year: 2022
Journal: Nat Commun
Title: Inactivation of the Hippo tumor suppressor pathway promotes melanoma.
Volume: 13
Issue: 1
Pages: 3732
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Publication
24200692 | J:207627
First Author: Marsh Durban V
Year: 2013
Journal: J Clin Invest
Title: Differential AKT dependency displayed by mouse models of BRAFV600E-initiated melanoma.
Volume: 123
Issue: 12
Pages: 5104-18
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Publication
36368445 | J:332391
     
First Author: Dong B
Year: 2022
Journal: J Invest Dermatol
Title: FZD6 Promotes Melanoma Cell Invasion but Not Proliferation by Regulating Canonical Wnt Signaling and Epithelial‒Mesenchymal Transition.
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Publication
29180473 | J:256302
First Author: Brighton HE
Year: 2018
Journal: Cancer Res
Title: New Mechanisms of Resistance to MEK Inhibitors in Melanoma Revealed by Intravital Imaging.
Volume: 78
Issue: 2
Pages: 542-557
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Publication
25472943 | J:221978
First Author: Deuker MM
Year: 2015
Journal: Cancer Discov
Title: PI3'-kinase inhibition forestalls the onset of MEK1/2 inhibitor resistance in BRAF-mutated melanoma.
Volume: 5
Issue: 2
Pages: 143-53
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Publication
24736544 | J:212454
First Author: Ho PC
Year: 2014
Journal: Cancer Res
Title: Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNγ.
Volume: 74
Issue: 12
Pages: 3205-17
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Publication
38743908 | J:349161
     
First Author: Nozawa A
Year: 2024
Journal: Hum Mol Genet
Title: Lymphatic endothelial cell-specific NRAS p.Q61R mutant embryos show abnormal lymphatic vessel morphogenesis.
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Publication
31679174 | J:282623
     
First Author: Aktary Z
Year: 2019
Journal: Pigment Cell Melanoma Res
Title: Sequencing two Tyr::CreERT2 transgenic mouse lines.
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Publication
29855541 | J:280263
First Author: Vial J
Year: 2019
Journal: Cell Death Differ
Title: The Ectodysplasin receptor EDAR acts as a tumor suppressor in melanoma by conditionally inducing cell death.
Volume: 26
Issue: 3
Pages: 443-454
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Publication
26923591 | J:234363
First Author: Micevic G
Year: 2016
Journal: Cell Rep
Title: DNMT3b Modulates Melanoma Growth by Controlling Levels of mTORC2 Component RICTOR.
Volume: 14
Issue: 9
Pages: 2180-2192
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Publication
27236105 | J:235072
First Author: Halaban R
Year: 2016
Journal: J Invest Dermatol
Title: RASopathy Gene Mutations in Melanoma.
Volume: 136
Issue: 9
Pages: 1755-9
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Publication
35422482 | J:324042
First Author: Martens S
Year: 2022
Journal: Cell Death Dis
Title: MLKL deficiency in BrafV600EPten-/- melanoma model results in a modest delay of nevi development and reduced lymph node dissemination in male mice.
Volume: 13
Issue: 4
Pages: 347
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Publication
21305688 | J:171522
First Author: Sandell LL
Year: 2011
Journal: Genesis
Title: A phenotype-driven ENU mutagenesis screen identifies novel alleles with functional roles in early mouse craniofacial development.
Volume: 49
Issue: 4
Pages: 342-59
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pten/Pten Tg(tetO-BRAF*V600E)29Lc/? Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129/Sv * C57BL/6J * FVB * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a Nras/Nras Stk11/Stk11 Tg(Tyr-cre/ERT2)13Bos/?
Background: B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Nras Cdkn2a Stk11
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(KRT14-rtTA)F42Efu/? Tg(tetO-EDN1,-lacZ)9Mhus/? Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mc1r/Mc1r Tg(KRT14-rtTA)F42Efu/? Tg(tetO-EDN1,-lacZ)9Mhus/? Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf<+> Ezh2/Ezh2<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ezh2/Ezh2<+> Nras/Nras<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(Tyr-cre/ERT2)13Bos/?
Background: STOCK Tg(Tyr-cre/ERT2)13Bos Gt(ROSA)26Sor/Gt(ROSA)26Sor/Cvrk
Zygosity: cn
Has Mutant Allele: true
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Publication
19903482 | J:155307
First Author: Baruzzi A
Year: 2010
Journal: FEBS Lett
Title: c-Abl and Src-family kinases cross-talk in regulation of myeloid cell migration.
Volume: 584
Issue: 1
Pages: 15-21
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Publication
9488481 | J:45936
First Author: Kawai T
Year: 1998
Journal: Mol Cell Biol
Title: ZIP kinase, a novel serine/threonine kinase which mediates apoptosis.
Volume: 18
Issue: 3
Pages: 1642-51
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Publication
10376525 | J:55856
First Author: Kawai T
Year: 1999
Journal: Oncogene
Title: Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity.
Volume: 18
Issue: 23
Pages: 3471-80
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Publication
11485996 | J:72366
First Author: Jin Y
Year: 2001
Journal: J Biol Chem
Title: Identification of a new form of death-associated protein kinase that promotes cell survival.
Volume: 276
Issue: 43
Pages: 39667-78
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Protein
Q8K2T1
Organism: Mus musculus/domesticus
Length: 309  
Fragment?: false
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Publication
15471878 | J:95160
First Author: Haegebarth A
Year: 2004
Journal: J Biol Chem
Title: The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2.
Volume: 279
Issue: 52
Pages: 54398-404
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Protein
Q9DC69
Organism: Mus musculus/domesticus
Length: 377  
Fragment?: false
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Protein
Q9ESV4
Organism: Mus musculus/domesticus
Length: 38  
Fragment?: true
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Protein
Q9CU43
Organism: Mus musculus/domesticus
Length: 52  
Fragment?: true
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Protein
D3YU12
Organism: Mus musculus/domesticus
Length: 299  
Fragment?: false
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Protein
A0A0R3P9C8
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: false
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Protein
Q3TT74
Organism: Mus musculus/domesticus
Length: 41  
Fragment?: true
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Protein
G5E8S7
Organism: Mus musculus/domesticus
Length: 291  
Fragment?: false
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Protein
G3UX71
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: false
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Protein
Q3UU38
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: false
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Protein
Q8BJM4
Organism: Mus musculus/domesticus
Length: 44  
Fragment?: true
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Publication
7780827 | -
First Author: Attwood PV
Year: 1995
Journal: Int J Biochem Cell Biol
Title: The structure and the mechanism of action of pyruvate carboxylase.
Volume: 27
Issue: 3
Pages: 231-49
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Publication
10229653 | -
 
First Author: Jitrapakdee S
Year: 1999
Journal: Biochem J
Title: Structure, function and regulation of pyruvate carboxylase.
Volume: 340 ( Pt 1)
Pages: 1-16
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Publication
23698000 | -
First Author: Lietzan AD
Year: 2013
Journal: J Biol Chem
Title: A substrate-induced biotin binding pocket in the carboxyltransferase domain of pyruvate carboxylase.
Volume: 288
Issue: 27
Pages: 19915-25
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Publication
9642265 | -
First Author: Schnappauf G
Year: 1998
Journal: J Biol Chem
Title: Tyrosine and tryptophan act through the same binding site at the dimer interface of yeast chorismate mutase.
Volume: 273
Issue: 27
Pages: 17012-7
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Publication
1826034 | -
First Author: Klein C
Year: 1991
Journal: J Mol Biol
Title: Structure of cyclodextrin glycosyltransferase refined at 2.0 A resolution.
Volume: 217
Issue: 4
Pages: 737-50
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Publication
8378335 | -
First Author: Chook YM
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Crystal structures of the monofunctional chorismate mutase from Bacillus subtilis and its complex with a transition state analog.
Volume: 90
Issue: 18
Pages: 8600-3
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Publication
31498992 | -
First Author: Gorman SD
Year: 2019
Journal: Biochemistry
Title: Energy and Enzyme Activity Landscapes of Yeast Chorismate Mutase at Cellular Concentrations of Allosteric Effectors.
Volume: 58
Issue: 39
Pages: 4058-4069
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Publication
14993460 | -
First Author: Griffith LC
Year: 2003
Journal: Mol Interv
Title: CaMKII, an enzyme on the move: regulation of temporospatial localization.
Volume: 3
Issue: 7
Pages: 386-403
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Publication
12603201 | -
First Author: Gangopadhyay SS
Year: 2003
Journal: Biochem J
Title: Differential functional properties of calmodulin-dependent protein kinase IIgamma variants isolated from smooth muscle.
Volume: 372
Issue: Pt 2
Pages: 347-57
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Publication
12829240 | -
First Author: Rykx A
Year: 2003
Journal: FEBS Lett
Title: Protein kinase D: a family affair.
Volume: 546
Issue: 1
Pages: 81-6
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Publication
12168951 | -
First Author: Kamei A
Year: 2002
Journal: DNA Res
Title: Biochemical examination of the potential eukaryotic-type protein kinase genes in the complete genome of the unicellular Cyanobacterium synechocystis sp. PCC 6803.
Volume: 9
Issue: 3
Pages: 71-8
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Publication
8331722 | -
First Author: Baylis SA
Year: 1993
Journal: J Virol
Title: African swine fever virus encodes a serine protein kinase which is packaged into virions.
Volume: 67
Issue: 8
Pages: 4549-56
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First Author: Yethon JA
Year: 2001
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First Author: Shani G
Year: 2001
Journal: EMBO J
Title: Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization and calmodulin binding.
Volume: 20
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First Author: Marcotte DJ
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Title: A novel mutation leading to a deletion in the SH3 domain of Bruton's tyrosine kinase.
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Year: 2000
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First Author: Brunner C
Year: 2005
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Title: Bruton's Tyrosine Kinase is involved in innate and adaptive immunity.
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First Author: Contreras CM
Year: 2007
Journal: Mol Immunol
Title: Btk regulates multiple stages in the development and survival of B-1 cells.
Volume: 44
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First Author: Kang SW
Year: 2001
Journal: EMBO J
Title: PKCbeta modulates antigen receptor signaling via regulation of Btk membrane localization.
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