Type |
Details |
Score |
Publication |
First Author: |
Tortola L |
Year: |
2019 |
Journal: |
J Allergy Clin Immunol |
Title: |
IL-21 promotes allergic airway inflammation by driving apoptosis of FoxP3+ regulatory T cells. |
Volume: |
143 |
Issue: |
6 |
Pages: |
2178-2189.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gu AD |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Requirements of transcription factor Smad-dependent and -independent TGF-β signaling to control discrete T-cell functions. |
Volume: |
109 |
Issue: |
3 |
Pages: |
905-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andersen L |
Year: |
2019 |
Journal: |
Cell Rep |
Title: |
The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells. |
Volume: |
29 |
Issue: |
13 |
Pages: |
4447-4459.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Becker M |
Year: |
2023 |
Journal: |
Cell Metab |
Title: |
Regulatory T cells require IL6 receptor alpha signaling to control skeletal muscle function and regeneration. |
Volume: |
35 |
Issue: |
10 |
Pages: |
1736-1751.e7 |
|
•
•
•
•
•
|
Publication |
First Author: |
de Kouchkovsky D |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
microRNA-17-92 regulates IL-10 production by regulatory T cells and control of experimental autoimmune encephalomyelitis. |
Volume: |
191 |
Issue: |
4 |
Pages: |
1594-605 |
|
•
•
•
•
•
|
Publication |
First Author: |
Browning LM |
Year: |
2018 |
Journal: |
Sci Signal |
Title: |
TGF-β-mediated enhancement of TH17 cell generation is inhibited by bone morphogenetic protein receptor 1α signaling. |
Volume: |
11 |
Issue: |
545 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Q |
Year: |
2017 |
Journal: |
Sci Immunol |
Title: |
LAG3 limits regulatory T cell proliferation and function in autoimmune diabetes. |
Volume: |
2 |
Issue: |
9 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ryu S |
Year: |
2024 |
Journal: |
J Headache Pain |
Title: |
Regulatory T cells require peripheral CCL2-CCR2 signaling to facilitate the resolution of medication overuse headache-related behavioral sensitization. |
Volume: |
25 |
Issue: |
1 |
Pages: |
197 |
|
•
•
•
•
•
|
Publication |
First Author: |
Parsa R |
Year: |
2012 |
Journal: |
Diabetes |
Title: |
Adoptive transfer of immunomodulatory M2 macrophages prevents type 1 diabetes in NOD mice. |
Volume: |
61 |
Issue: |
11 |
Pages: |
2881-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bettini M |
Year: |
2014 |
Journal: |
J Immunol |
Title: |
TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential. |
Volume: |
193 |
Issue: |
2 |
Pages: |
571-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schwarz A |
Year: |
2012 |
Journal: |
J Invest Dermatol |
Title: |
1,25-dihydroxyvitamin D exerts similar immunosuppressive effects as UVR but is dispensable for local UVR-induced immunosuppression. |
Volume: |
132 |
Issue: |
12 |
Pages: |
2762-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mariño E |
Year: |
2017 |
Journal: |
Nat Immunol |
Title: |
Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes. |
Volume: |
18 |
Issue: |
5 |
Pages: |
552-562 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hall JA |
Year: |
2011 |
Journal: |
Immunity |
Title: |
Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alpha. |
Volume: |
34 |
Issue: |
3 |
Pages: |
435-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hand LE |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
Regulatory T cells confer a circadian signature on inflammatory arthritis. |
Volume: |
11 |
Issue: |
1 |
Pages: |
1658 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pabbisetty SK |
Year: |
2016 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Peripheral tolerance can be modified by altering KLF2-regulated Treg migration. |
Volume: |
113 |
Issue: |
32 |
Pages: |
E4662-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Neumann K |
Year: |
2015 |
Journal: |
Eur J Immunol |
Title: |
Liver sinusoidal endothelial cells induce immunosuppressive IL-10-producing Th1 cells via the Notch pathway. |
Volume: |
45 |
Issue: |
7 |
Pages: |
2008-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Khan AR |
Year: |
2015 |
Journal: |
Eur J Immunol |
Title: |
Ligation of TLR7 on CD19(+) CD1d(hi) B cells suppresses allergic lung inflammation via regulatory T cells. |
Volume: |
45 |
Issue: |
6 |
Pages: |
1842-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee AJ |
Year: |
2010 |
Journal: |
J Biol Chem |
Title: |
CARMA1 regulation of regulatory T cell development involves modulation of interleukin-2 receptor signaling. |
Volume: |
285 |
Issue: |
21 |
Pages: |
15696-703 |
|
•
•
•
•
•
|
Publication |
First Author: |
Axisa PP |
Year: |
2022 |
Journal: |
Sci Transl Med |
Title: |
A multiple sclerosis-protective coding variant reveals an essential role for HDAC7 in regulatory T cells. |
Volume: |
14 |
Issue: |
675 |
Pages: |
eabl3651 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cervantes-Barragán L |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
Regulatory T cells selectively preserve immune privilege of self-antigens during viral central nervous system infection. |
Volume: |
188 |
Issue: |
8 |
Pages: |
3678-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mittermüller D |
Year: |
2023 |
Journal: |
JCI Insight |
Title: |
Regulatory T cells suppress the motility of cytotoxic T cells in Friend retrovirus-infected mice. |
Volume: |
8 |
Issue: |
13 |
|
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, targeted mutation, transgenic, congenic |
|
•
•
•
•
•
|
Publication |
First Author: |
Sequeira I |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
Immunomodulatory role of Keratin 76 in oral and gastric cancer. |
Volume: |
9 |
Issue: |
1 |
Pages: |
3437 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Foxp3/Foxp3<+> B9d2/Tgfb1/Tgfb1 Tg(Cd4-cre)1Cwi/? |
Background: |
involves: 129S6/SvEvTac * C57BL/6 * DBA/2 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Dicer1/Dicer1 Tg(Foxp3-EGFP/icre)1aJbs/? |
Background: |
involves: 129 * NOD/ShiLt |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Lag3/Lag3 Tg(Foxp3-EGFP/cre)1cJbs/? |
Background: |
NOD.Cg-Lag3 Tg(Foxp3-EGFP/cre)1cJbs |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Lag3/Lag3<+> Tg(Foxp3-EGFP/cre)1cJbs/? |
Background: |
NOD.Cg-Lag3 Tg(Foxp3-EGFP/cre)1cJbs |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rag1/Rag1 Tg(Foxp3-EGFP/cre)1cJbs/? |
Background: |
NOD.Cg-Rag1 Tg(Foxp3-EGFP/cre)1cJbs/J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Feofanova NA |
Year: |
2022 |
Journal: |
PLoS One |
Title: |
L-fucose reduces gut inflammation due to T-regulatory response in Muc2 null mice. |
Volume: |
17 |
Issue: |
12 |
Pages: |
e0278714 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou Y |
Year: |
2015 |
Journal: |
Cardiovasc Res |
Title: |
Regulatory T cells in human and angiotensin II-induced mouse abdominal aortic aneurysms. |
Volume: |
107 |
Issue: |
1 |
Pages: |
98-107 |
|
•
•
•
•
•
|
Publication |
First Author: |
Canault M |
Year: |
2008 |
Journal: |
J Pathol |
Title: |
Progression of atherosclerosis in ApoE-deficient mice that express distinct molecular forms of TNF-alpha. |
Volume: |
214 |
Issue: |
5 |
Pages: |
574-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee CW |
Year: |
2007 |
Journal: |
Infect Immun |
Title: |
Wild-type and interleukin-10-deficient regulatory T cells reduce effector T-cell-mediated gastroduodenitis in Rag2-/- mice, but only wild-type regulatory T cells suppress Helicobacter pylori gastritis. |
Volume: |
75 |
Issue: |
6 |
Pages: |
2699-707 |
|
•
•
•
•
•
|
Publication |
First Author: |
Konkel JE |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Thymocyte apoptosis drives the intrathymic generation of regulatory T cells. |
Volume: |
111 |
Issue: |
4 |
Pages: |
E465-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hooper KM |
Year: |
2017 |
Journal: |
PLoS One |
Title: |
Prostaglandin E2 inhibits Tr1 cell differentiation through suppression of c-Maf. |
Volume: |
12 |
Issue: |
6 |
Pages: |
e0179184 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nair RE |
Year: |
2006 |
Journal: |
J Immunol |
Title: |
Chronic immune therapy induces a progressive increase in intratumoral T suppressor activity and a concurrent loss of tumor-specific CD8+ T effectors in her-2/neu transgenic mice bearing advanced spontaneous tumors. |
Volume: |
176 |
Issue: |
12 |
Pages: |
7325-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
DuBois JC |
Year: |
2019 |
Journal: |
Front Immunol |
Title: |
Akt3-Mediated Protection Against Inflammatory Demyelinating Disease. |
Volume: |
10 |
|
Pages: |
1738 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ragni MV |
Year: |
2009 |
Journal: |
Exp Hematol |
Title: |
Factor VIII-pulsed dendritic cells reduce anti-factor VIII antibody formation in the hemophilia A mouse model. |
Volume: |
37 |
Issue: |
6 |
Pages: |
744-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hamers AA |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Deficiency of Nuclear Receptor Nur77 Aggravates Mouse Experimental Colitis by Increased NFκB Activity in Macrophages. |
Volume: |
10 |
Issue: |
8 |
Pages: |
e0133598 |
|
•
•
•
•
•
|
Publication |
First Author: |
Graber DJ |
Year: |
2024 |
Journal: |
Cytotherapy |
Title: |
Human CD4+CD25+ T cells expressing a chimeric antigen receptor against aberrant superoxide dismutase 1 trigger antigen-specific immunomodulation. |
Volume: |
26 |
Issue: |
2 |
Pages: |
126-135 |
|
•
•
•
•
•
|
Publication |
First Author: |
Burger-van Paassen N |
Year: |
2011 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Colitis development during the suckling-weaning transition in mucin Muc2-deficient mice. |
Volume: |
301 |
Issue: |
4 |
Pages: |
G667-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ohtani M |
Year: |
2011 |
Journal: |
Carcinogenesis |
Title: |
17 β-estradiol suppresses Helicobacter pylori-induced gastric pathology in male hypergastrinemic INS-GAS mice. |
Volume: |
32 |
Issue: |
8 |
Pages: |
1244-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakajima-Adachi H |
Year: |
2017 |
Journal: |
PLoS One |
Title: |
Critical role of intestinal interleukin-4 modulating regulatory T cells for desensitization, tolerance, and inflammation of food allergy. |
Volume: |
12 |
Issue: |
2 |
Pages: |
e0172795 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shibata Y |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
The Role of Indoleamine 2,3-Dioxygenase in Diethylnitrosamine-Induced Liver Carcinogenesis. |
Volume: |
11 |
Issue: |
1 |
Pages: |
e0146279 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wandu WS |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Leucine-Rich Repeat Kinase 2 (Lrrk2) Deficiency Diminishes the Development of Experimental Autoimmune Uveitis (EAU) and the Adaptive Immune Response. |
Volume: |
10 |
Issue: |
6 |
Pages: |
e0128906 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takeda A |
Year: |
2014 |
Journal: |
Exp Eye Res |
Title: |
EBI3 is pivotal for the initiation of experimental autoimmune uveitis. |
Volume: |
125 |
|
Pages: |
107-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Akimova T |
Year: |
2024 |
Journal: |
Front Immunol |
Title: |
Antisense targeting of FOXP3+ Tregs to boost anti-tumor immunity. |
Volume: |
15 |
|
Pages: |
1426657 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu S |
Year: |
2023 |
Journal: |
Mol Immunol |
Title: |
3, 3'-diindolylmethane, a natural aryl hydrocarbon receptor agonist, alleviates ulcerative colitis by enhancing "glycolysis-lactate-STAT3″ and TIP60 signals-mediated Treg differentiation. |
Volume: |
163 |
|
Pages: |
147-162 |
|
•
•
•
•
•
|
Publication |
First Author: |
Han Y |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1. |
Volume: |
182 |
Issue: |
1 |
Pages: |
111-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gückel E |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
Cell-intrinsic NF-κB activation is critical for the development of natural regulatory T cells in mice. |
Volume: |
6 |
Issue: |
5 |
Pages: |
e20003 |
|
•
•
•
•
•
|
Publication |
First Author: |
McGee HS |
Year: |
2010 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Programmed Death-1 antibody blocks therapeutic effects of T-regulatory cells in cockroach antigen-induced allergic asthma. |
Volume: |
43 |
Issue: |
4 |
Pages: |
432-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tyagi AM |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Estrogen deficiency induces the differentiation of IL-17 secreting Th17 cells: a new candidate in the pathogenesis of osteoporosis. |
Volume: |
7 |
Issue: |
9 |
Pages: |
e44552 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim HR |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Attenuation of experimental colitis in glutathione peroxidase 1 and catalase double knockout mice through enhancing regulatory T cell function. |
Volume: |
9 |
Issue: |
4 |
Pages: |
e95332 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yasuma K |
Year: |
2016 |
Journal: |
PLoS Pathog |
Title: |
HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT). |
Volume: |
12 |
Issue: |
1 |
Pages: |
e1005372 |
|
•
•
•
•
•
|
Publication |
First Author: |
He C |
Year: |
2018 |
Journal: |
Immunol Lett |
Title: |
Effects of Toll-like receptor 4 on β2-glycoprotein I-induced splenic T cell subsets differentiation. |
Volume: |
198 |
|
Pages: |
17-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shi G |
Year: |
2023 |
Journal: |
Cancers (Basel) |
Title: |
TNFR1 and TNFR2, Which Link NF-κB Activation, Drive Lung Cancer Progression, Cell Dedifferentiation, and Metastasis. |
Volume: |
15 |
Issue: |
17 |
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
314
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Hassler T |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Inventories of naive and tolerant mouse CD4 T cell repertoires reveal a hierarchy of deleted and diverted T cell receptors. |
Volume: |
116 |
Issue: |
37 |
Pages: |
18537-18543 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tyagi AM |
Year: |
2018 |
Journal: |
Immunity |
Title: |
The Microbial Metabolite Butyrate Stimulates Bone Formation via T Regulatory Cell-Mediated Regulation of WNT10B Expression. |
Volume: |
49 |
Issue: |
6 |
Pages: |
1116-1131.e7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Littmann ER |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
Host immunity modulates the efficacy of microbiota transplantation for treatment of Clostridioides difficile infection. |
Volume: |
12 |
Issue: |
1 |
Pages: |
755 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang D |
Year: |
2017 |
Journal: |
Nat Med |
Title: |
D-mannose induces regulatory T cells and suppresses immunopathology. |
Volume: |
23 |
Issue: |
9 |
Pages: |
1036-1045 |
|
•
•
•
•
•
|
Publication |
First Author: |
Paul-Heng M |
Year: |
2018 |
Journal: |
JCI Insight |
Title: |
Direct recognition of hepatocyte-expressed MHC class I alloantigens is required for tolerance induction. |
Volume: |
3 |
Issue: |
15 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Guo Z |
Year: |
2020 |
Journal: |
J Clin Invest |
Title: |
DCAF1 regulates Treg senescence via the ROS axis during immunological aging. |
Volume: |
130 |
Issue: |
11 |
Pages: |
5893-5908 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hubert S |
Year: |
2010 |
Journal: |
J Exp Med |
Title: |
Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2-P2X7 pathway. |
Volume: |
207 |
Issue: |
12 |
Pages: |
2561-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shahneh F |
Year: |
2021 |
Journal: |
Blood |
Title: |
Specialized regulatory T cells control venous blood clot resolution through SPARC. |
Volume: |
137 |
Issue: |
11 |
Pages: |
1517-1526 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pellegrini M |
Year: |
2009 |
Journal: |
Nat Med |
Title: |
Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies. |
Volume: |
15 |
Issue: |
5 |
Pages: |
528-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gkountidi AO |
Year: |
2021 |
Journal: |
Cancer Immunol Res |
Title: |
MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell-Suppressive Functions. |
Volume: |
9 |
Issue: |
7 |
Pages: |
748-764 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ono N |
Year: |
2017 |
Journal: |
PLoS One |
Title: |
Exposure to sequestered self-antigens in vivo is not sufficient for the induction of autoimmune diabetes. |
Volume: |
12 |
Issue: |
3 |
Pages: |
e0173176 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okato A |
Year: |
2024 |
Journal: |
J Clin Invest |
Title: |
FGFR inhibition augments anti-PD-1 efficacy in murine FGFR3-mutant bladder cancer by abrogating immunosuppression. |
Volume: |
134 |
Issue: |
2 |
|
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tgfbr2/Tgfbr2 Tg(Foxp3-EGFP/cre)1cJbs/? Tg(TcraBDC2.5,TcrbBDC2.5)1Doi/? |
Background: |
involves: 129S6/SvEvTac * C57BL/6 * NOD * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
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