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Search results 2601 to 2700 out of 3295 for Kras

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Type Details Score
Publication
15102471 | J:114108
First Author: Papin J
Year: 2004
Journal: Curr Opin Biotechnol
Title: Bioinformatics and cellular signaling.
Volume: 15
Issue: 1
Pages: 78-81
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Publication
9371744 | J:44483
First Author: Brady KP
Year: 1997
Journal: Genome Res
Title: Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.
Volume: 7
Issue: 11
Pages: 1085-93
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
21731673 | J:174767
First Author: Tang F
Year: 2011
Journal: PLoS One
Title: Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
Volume: 6
Issue: 6
Pages: e21208
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Publication
- | J:46439
     
First Author: Freeman TC
Year: 1998
Journal: MGI Direct Data Submission
Title: Expression Mapping of Mouse Genes
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Publication
- | J:15839
       
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
34531315 | J:323056
First Author: Hou P
Year: 2021
Journal: Genes Dev
Title: USP21 deubiquitinase elevates macropinocytosis to enable oncogenic KRAS bypass in pancreatic cancer.
Volume: 35
Issue: 19-20
Pages: 1327-1332
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Publication
28607485 | J:252219
First Author: Kamerkar S
Year: 2017
Journal: Nature
Title: Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer.
Volume: 546
Issue: 7659
Pages: 498-503
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Publication
30988000 | J:276866
 
First Author: Byun JK
Year: 2019
Journal: EMBO Rep
Title: Oncogenic KRAS signaling activates mTORC1 through COUP-TFII-mediated lactate production.
Volume: 20
Issue: 6
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Publication
37775182 | J:360543
First Author: Han J
Year: 2023
Journal: Genes Dev
Title: Stromal-derived NRG1 enables oncogenic KRAS bypass in pancreas cancer.
Volume: 37
Issue: 17-18
Pages: 818-828
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Allele
Kras<tm4.1Bbd> | MGI:5649285
Name: Kirsten rat sarcoma viral oncogene homolog; targeted mutation 4.1, Mariano Barbacid
Allele Type: Targeted
Attribute String: Humanized sequence
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Publication
31263025 | J:278961
First Author: Humpton TJ
Year: 2019
Journal: Cancer Discov
Title: Oncogenic KRAS Induces NIX-Mediated Mitophagy to Promote Pancreatic Cancer.
Volume: 9
Issue: 9
Pages: 1268-1287
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Publication
36369466 | J:332252
First Author: Won Y
Year: 2022
Journal: Exp Mol Med
Title: Mouse models of Kras activation in gastric cancer.
Volume: 54
Issue: 11
Pages: 1793-1798
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Publication
38975874 | J:357844
First Author: Dilly J
Year: 2024
Journal: Cancer Discov
Title: Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer.
Volume: 14
Issue: 11
Pages: 2135-2161
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Publication
39819877 | J:361448
First Author: Koo H
Year: 2025
Journal: Nat Commun
Title: Anti-proteolytic regulation of KRAS by USP9X/NDRG3 in KRAS-driven cancer development.
Volume: 16
Issue: 1
Pages: 628
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Publication
15894260 | J:98833
First Author: Siveke JT
Year: 2005
Journal: Cancer Cell
Title: Chromosomal instability in mouse metastatic pancreatic cancer--it's Kras and Tp53 after all.
Volume: 7
Issue: 5
Pages: 405-7
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Publication
31521603 | J:349043
First Author: Brubaker DK
Year: 2019
Journal: Cell Syst
Title: Proteogenomic Network Analysis of Context-Specific KRAS Signaling in Mouse-to-Human Cross-Species Translation.
Volume: 9
Issue: 3
Pages: 258-270.e6
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Publication
29263151 | J:253861
First Author: Dias Carvalho P
Year: 2018
Journal: Cancer Res
Title: KRAS Oncogenic Signaling Extends beyond Cancer Cells to Orchestrate the Microenvironment.
Volume: 78
Issue: 1
Pages: 7-14
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Publication
33082413 | J:298994
First Author: Ryu HH
Year: 2020
Journal: Sci Rep
Title: Neuron type-specific expression of a mutant KRAS impairs hippocampal-dependent learning and memory.
Volume: 10
Issue: 1
Pages: 17730
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Publication
31461438 | J:279455
First Author: Gao W
Year: 2019
Journal: PLoS Biol
Title: Targeting oxidative pentose phosphate pathway prevents recurrence in mutant Kras colorectal carcinomas.
Volume: 17
Issue: 8
Pages: e3000425
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Publication
31646336 | J:296247
First Author: O'Brien G
Year: 2020
Journal: Carcinogenesis
Title: Kras mutations and PU.1 promoter methylation are new pathways in murine radiation-induced AML.
Volume: 41
Issue: 8
Pages: 1104-1112
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Publication
34857889 | J:321217
First Author: Alhayyani S
Year: 2022
Journal: Oncogene
Title: Oncogenic dependency on STAT3 serine phosphorylation in KRAS mutant lung cancer.
Volume: 41
Issue: 6
Pages: 809-823
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Protein Coding Gene
MGI:1353511 | Sspn
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
29321164 | J:258681
First Author: Fujimura K
Year: 2018
Journal: Cancer Res
Title: KRAS Oncoprotein Expression Is Regulated by a Self-Governing eIF5A-PEAK1 Feed-Forward Regulatory Loop.
Volume: 78
Issue: 6
Pages: 1444-1456
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Publication
36451866 | J:331710
First Author: Luo YD
Year: 2022
Journal: Theranostics
Title: Mutant Kras and mTOR crosstalk drives hepatocellular carcinoma development via PEG3/STAT3/BEX2 signaling.
Volume: 12
Issue: 18
Pages: 7903-7919
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Publication
24576621 | J:210526
First Author: Roper J
Year: 2014
Journal: Cancer Lett
Title: Combination PI3K/MEK inhibition promotes tumor apoptosis and regression in PIK3CA wild-type, KRAS mutant colorectal cancer.
Volume: 347
Issue: 2
Pages: 204-11
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HT Experiment
E-GEOD-27656 | Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in ovary and testis
Series Id: GSE27656
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
30995478 | J:288496
First Author: Choi H
Year: 2019
Journal: Cell Rep
Title: Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer.
Volume: 27
Issue: 3
Pages: 806-819.e5
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Publication
28320962 | J:242037
First Author: Mou H
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Genetic disruption of oncogenic Kras sensitizes lung cancer cells to Fas receptor-mediated apoptosis.
Volume: 114
Issue: 14
Pages: 3648-3653
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Publication
30104206 | J:266078
First Author: Mackedenski S
Year: 2018
Journal: Biochem J
Title: Characterizing the interaction between insulin-like growth factor 2 mRNA-binding protein 1 (IMP1) and KRAS expression.
Volume: 475
Issue: 17
Pages: 2749-2767
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Publication
37277019 | J:336651
 
First Author: Liu ZY
Year: 2023
Journal: Cancer Lett
Title: FBXW10-S6K1 promotes ANXA2 polyubiquitination and KRAS activation to drive hepatocellular carcinoma development in males.
Volume: 566
Pages: 216257
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Publication
38975873 | J:357840
First Author: Singhal A
Year: 2024
Journal: Cancer Discov
Title: A Classical Epithelial State Drives Acute Resistance to KRAS Inhibition in Pancreatic Cancer.
Volume: 14
Issue: 11
Pages: 2122-2134
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Publication
37067057 | J:335421
First Author: Tomoshige K
Year: 2023
Journal: Cancer Res
Title: FOXA2 Cooperates with Mutant KRAS to Drive Invasive Mucinous Adenocarcinoma of the Lung.
Volume: 83
Issue: 9
Pages: 1443-1458
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Interaction Experiment
Liu ZY (2023)
Description: FBXW10-S6K1 promotes ANXA2 polyubiquitination and KRAS activation to drive hepatocellular carcinoma development in males.
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Publication
31390566 | J:288429
First Author: Campbell KM
Year: 2019
Journal: Cell Rep
Title: A Spontaneous Aggressive ERα+ Mammary Tumor Model Is Driven by Kras Activation.
Volume: 28
Issue: 6
Pages: 1526-1537.e4
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Publication
- | J:311938
     
First Author: de Carne Trecesson S
Year: 2020
Journal: bioRxiv
Title: APOBEC3B expression generates an immunogenetic model of Kras mutant lung cancer.
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Publication
26047463 | J:223771
 
First Author: Unni AM
Year: 2015
Journal: Elife
Title: Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma.
Volume: 4
Pages: e06907
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Publication
30853214 | J:275999
First Author: Hu CM
Year: 2019
Journal: Cell Metab
Title: High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells.
Volume: 29
Issue: 6
Pages: 1334-1349.e10
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Publication
36693323 | J:333004
First Author: Chatzeli L
Year: 2023
Journal: Dev Cell
Title: A cellular hierarchy of Notch and Kras signaling controls cell fate specification in the developing mouse salivary gland.
Volume: 58
Issue: 2
Pages: 94-109.e6
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Publication
39232498 | J:361502
First Author: Yang D
Year: 2024
Journal: Cell Rep Med
Title: Loss of p53 and SMAD4 induces adenosquamous subtype pancreatic cancer in the absence of an oncogenic KRAS mutation.
Volume: 5
Issue: 9
Pages: 101711
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Genotype
Genotype
Symbol: Kras/Kras
Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6J * FVB/N
Zygosity: hm
Has Mutant Allele: true
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Publication
8859779 | J:40417
First Author: Chiappetta G
Year: 1996
Journal: Oncol Res
Title: Transgenic mice carrying the human KRAS oncogene under the control of a thyroglobulin promoter: KRAS expression in thyroids analyzed by in situ hybridization.
Volume: 8
Issue: 2
Pages: 85-93
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Publication
35247892 | J:324782
First Author: Nagao M
Year: 2022
Journal: Cancer Res
Title: Concurrent Activation of Kras and Canonical Wnt Signaling Induces Premalignant Lesions That Progress to Extrahepatic Biliary Cancer in Mice.
Volume: 82
Issue: 9
Pages: 1803-1817
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Publication
17510423 | J:121738
First Author: Ji H
Year: 2007
Journal: Cancer Res
Title: Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models.
Volume: 67
Issue: 10
Pages: 4933-9
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Publication
29844447 | J:263205
First Author: Weng TY
Year: 2018
Journal: Sci Rep
Title: Homoharringtonine induced immune alteration for an Efficient Anti-tumor Response in Mouse Models of Non-small Cell Lung Adenocarcinoma Expressing Kras Mutation.
Volume: 8
Issue: 1
Pages: 8216
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Publication
19609923 | J:157052
First Author: Dwyer-Nield LD
Year: 2010
Journal: Int J Cancer
Title: Epistatic interactions govern chemically-induced lung tumor susceptibility and Kras mutation site in murine C57BL/6J-ChrA/J chromosome substitution strains.
Volume: 126
Issue: 1
Pages: 125-32
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Publication
39412982 | J:361617
First Author: Fey SK
Year: 2025
Journal: Cancer Res
Title: KRAS Loss of Heterozygosity Promotes MAPK-Dependent Pancreatic Ductal Adenocarcinoma Initiation and Induces Therapeutic Sensitivity to MEK Inhibition.
Volume: 85
Issue: 2
Pages: 251-262
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Publication
29912950 | J:263352
First Author: Dompe N
Year: 2018
Journal: PLoS One
Title: A CRISPR screen identifies MAPK7 as a target for combination with MEK inhibition in KRAS mutant NSCLC.
Volume: 13
Issue: 6
Pages: e0199264
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Publication
30353028 | J:268435
First Author: Mohamed AD
Year: 2018
Journal: Sci Rep
Title: Analysis of the relationship between the KRAS G12V oncogene and the Hippo effector YAP1 in embryonal rhabdomyosarcoma.
Volume: 8
Issue: 1
Pages: 15674
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Publication
26173780 | J:320864
 
First Author: Chakrabarti G
Year: 2015
Journal: Radiat Oncol
Title: Mutant KRAS associated malic enzyme 1 expression is a predictive marker for radiation therapy response in non-small cell lung cancer.
Volume: 10
Pages: 145
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Publication
28400509 | J:242240
First Author: Gouw AM
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Oncogene KRAS activates fatty acid synthase, resulting in specific ERK and lipid signatures associated with lung adenocarcinoma.
Volume: 114
Issue: 17
Pages: 4300-4305
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HT Experiment
E-GEOD-16114 | Transcription profiling of mouse 26-day-old K-ras conditional mutant mice and 3-month-old K-ras conditional mutant mice reveals cell-specific Kras and Pten mutations document proliferation arrest in granulosa cells vs. oncogenic insult to OSE cells
Series Id: GSE16114
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Transgene
MGI:3696798 | Tg(Fabp2-KRAS*Val12)#Jig
Type: transgene
Organism: mouse, laboratory
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HT Experiment
E-MTAB-3436 | RelA in pancreatic cancer
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
12359767 | J:79689
First Author: Uhrbom L
Year: 2002
Journal: Cancer Res
Title: Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt.
Volume: 62
Issue: 19
Pages: 5551-8
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Publication
34769463 | J:314700
 
First Author: Mickler EA
Year: 2021
Journal: Int J Mol Sci
Title: Low-Coverage Whole Genome Sequencing Using Laser Capture Microscopy with Combined Digital Droplet PCR: An Effective Tool to Study Copy Number and Kras Mutations in Early Lung Adenocarcinoma Development.
Volume: 22
Issue: 21
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Publication
22525269 | J:193362
First Author: Hollern DP
Year: 2013
Journal: Oncogene
Title: A mouse model with T58A mutations in Myc reduces the dependence on KRas mutations and has similarities to claudin-low human breast cancer.
Volume: 32
Issue: 10
Pages: 1296-304
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Publication
35646902 | J:324985
 
First Author: Ding L
Year: 2022
Journal: Front Cell Dev Biol
Title: Nuclear GSK-3β and Oncogenic KRas Lead to the Retention of Pancreatic Ductal Progenitor Cells Phenotypically Similar to Those Seen in IPMN.
Volume: 10
Pages: 853003
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Publication
23536778 | J:199528
First Author: König K
Year: 2013
Journal: PLoS One
Title: Loss of the keratin cytoskeleton is not sufficient to induce epithelial mesenchymal transition in a novel KRAS driven sporadic lung cancer mouse model.
Volume: 8
Issue: 3
Pages: e57996
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DO Term
DOID:0060581 | Noonan syndrome 3
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DO Term
DOID:0111461 | cardiofaciocutaneous syndrome 2
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DO Term
DOID:0110117 | autoimmune lymphoproliferative syndrome type 4
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Allele
Braf<tm1Bbd> | MGI:4946645
Name: Braf transforming gene; targeted mutation 1, Mariano Barbacid
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Hypomorph
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Allele
Braf<tm1Tumg> | MGI:5902220
Name: Braf transforming gene; targeted mutation 1, Yoko Aoki
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Map2k1<tm2.1Chrn> | MGI:6157680
Name: mitogen-activated protein kinase kinase 1; targeted mutation 2.1, M Jean Charron
Allele Type: Targeted
Attribute String: Humanized sequence
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DO Term
DOID:0111705 | oculoectodermal syndrome
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Publication
31406347 | -
First Author: Nissim S
Year: 2019
Journal: Nat Genet
Title: Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer.
Volume: 51
Issue: 9
Pages: 1308-1314
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Allele
Bhlha15<tm2(Kras)Skz> | MGI:3615274
 
Name: basic helix-loop-helix family, member a15; targeted mutation 2, Stephen F Konieczny
Allele Type: Targeted
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Allele
Stk11<tm1.2Rdp> | MGI:2387403
Name: serine/threonine kinase 11; targeted mutation 1.2, Ronald DePinho
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
32719131 | J:293934
First Author: Niitsu Y
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: A CRAF/glutathione-S-transferase P1 complex sustains autocrine growth of cancers with KRAS and BRAF mutations.
Volume: 117
Issue: 32
Pages: 19435-19445
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