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Search results 2601 to 2700 out of 3210 for Lepr

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Type Details Score
Publication
24516131 | J:206823
First Author: Hoshino A
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of p53 preserves Parkin-mediated mitophagy and pancreatic β-cell function in diabetes.
Volume: 111
Issue: 8
Pages: 3116-21
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25249008 | J:324511
First Author: Mohamed R
Year: 2014
Journal: J Mol Med (Berl)
Title: Urinary semaphorin 3A correlates with diabetic proteinuria and mediates diabetic nephropathy and associated inflammation in mice.
Volume: 92
Issue: 12
Pages: 1245-56
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Publication
34031386 | J:337333
First Author: Deng J
Year: 2021
Journal: Nat Commun
Title: The metabolic hormone leptin promotes the function of T(FH) cells and supports vaccine responses.
Volume: 12
Issue: 1
Pages: 3073
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Publication
15181014 | J:121205
First Author: Shi H
Year: 2004
Journal: J Biol Chem
Title: Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling.
Volume: 279
Issue: 33
Pages: 34733-40
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Publication
21081500 | J:268787
First Author: Im SS
Year: 2011
Journal: J Biol Chem
Title: Peroxisome proliferator-activated receptor {alpha} is responsible for the up-regulation of hepatic glucose-6-phosphatase gene expression in fasting and db/db Mice.
Volume: 286
Issue: 2
Pages: 1157-64
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Publication
23447682 | J:194839
First Author: Yu Y
Year: 2013
Journal: J Immunol
Title: Cutting edge: Leptin-induced RORγt expression in CD4+ T cells promotes Th17 responses in systemic lupus erythematosus.
Volume: 190
Issue: 7
Pages: 3054-8
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Publication
31978605 | J:292718
 
First Author: Thebeau C
Year: 2020
Journal: Neurobiol Dis
Title: Light deprivation reduces the severity of experimental diabetic retinopathy.
Volume: 137
Pages: 104754
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Publication
19036876 | J:158084
First Author: Gerin I
Year: 2009
Journal: Endocrinology
Title: Hyperphagia and obesity in female mice lacking tissue inhibitor of metalloproteinase-1.
Volume: 150
Issue: 4
Pages: 1697-704
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Publication
30785802 | J:292059
First Author: Wang M
Year: 2019
Journal: FASEB J
Title: High glucose-induced ubiquitination of G6PD leads to the injury of podocytes.
Volume: 33
Issue: 5
Pages: 6296-6310
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Publication
17595213 | J:125421
First Author: Iwakura H
Year: 2007
Journal: Am J Physiol Endocrinol Metab
Title: Effects of ghrelin administration on decreased growth hormone status in obese animals.
Volume: 293
Issue: 3
Pages: E819-25
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Publication
25249578 | J:252880
First Author: Tsuneki H
Year: 2015
Journal: Diabetes
Title: Hypothalamic orexin prevents hepatic insulin resistance via daily bidirectional regulation of autonomic nervous system in mice.
Volume: 64
Issue: 2
Pages: 459-70
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Publication
28270521 | J:246071
First Author: Chen Q
Year: 2017
Journal: Diabetes
Title: Pathogenic Role of microRNA-21 in Diabetic Retinopathy Through Downregulation of PPARα.
Volume: 66
Issue: 6
Pages: 1671-1682
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Publication
17202473 | J:117213
First Author: Münzberg H
Year: 2007
Journal: J Neurosci
Title: Appropriate inhibition of orexigenic hypothalamic arcuate nucleus neurons independently of leptin receptor/STAT3 signaling.
Volume: 27
Issue: 1
Pages: 69-74
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Publication
28377411 | J:259091
 
First Author: Marcel N
Year: 2017
Journal: Sci Signal
Title: The lysine deacetylase Sirtuin 1 modulates the localization and function of the Notch1 receptor in regulatory T cells.
Volume: 10
Issue: 473
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Publication
27188441 | J:259060
First Author: Xiao F
Year: 2016
Journal: Sci Signal
Title: BTG1 ameliorates liver steatosis by decreasing stearoyl-CoA desaturase 1 (SCD1) abundance and altering hepatic lipid metabolism.
Volume: 9
Issue: 428
Pages: ra50
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Publication
26647385 | J:246081
First Author: Soares MA
Year: 2016
Journal: Diabetes
Title: Restoration of Nrf2 Signaling Normalizes the Regenerative Niche.
Volume: 65
Issue: 3
Pages: 633-46
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Publication
27938665 | J:239449
   
First Author: Gomez JA
Year: 2016
Journal: Elife
Title: Experimental reconstitution of chronic ER stress in the liver reveals feedback suppression of BiP mRNA expression.
Volume: 5
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30135249 | J:266281
 
First Author: Mazor R
Year: 2018
Journal: Sci Transl Med
Title: Cleavage of the leptin receptor by matrix metalloproteinase-2 promotes leptin resistance and obesity in mice.
Volume: 10
Issue: 455
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18583460 | J:141913
First Author: Zyromski NJ
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: A murine model of obesity implicates the adipokine milieu in the pathogenesis of severe acute pancreatitis.
Volume: 295
Issue: 3
Pages: G552-8
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Publication
20647313 | J:166388
First Author: Gao D
Year: 2010
Journal: J Biol Chem
Title: The effects of palmitate on hepatic insulin resistance are mediated by NADPH Oxidase 3-derived reactive oxygen species through JNK and p38MAPK pathways.
Volume: 285
Issue: 39
Pages: 29965-73
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24166765 | J:203061
First Author: Gao Y
Year: 2014
Journal: Glia
Title: Hormones and diet, but not body weight, control hypothalamic microglial activity.
Volume: 62
Issue: 1
Pages: 17-25
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Publication
26324179 | J:246165
First Author: Liu Y
Year: 2015
Journal: Diabetes
Title: Protein Inhibitor of Activated STAT 1 (PIAS1) Protects Against Obesity-Induced Insulin Resistance by Inhibiting Inflammation Cascade in Adipose Tissue.
Volume: 64
Issue: 12
Pages: 4061-74
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Publication
15616008 | J:105084
First Author: Liu Y
Year: 2005
Journal: Diabetes
Title: Increased glucocorticoid receptor and 11{beta}-hydroxysteroid dehydrogenase type 1 expression in hepatocytes may contribute to the phenotype of type 2 diabetes in db/db mice.
Volume: 54
Issue: 1
Pages: 32-40
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Publication
24273001 | J:207097
First Author: Saucillo DC
Year: 2014
Journal: J Immunol
Title: Leptin metabolically licenses T cells for activation to link nutrition and immunity.
Volume: 192
Issue: 1
Pages: 136-44
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34913989 | J:322738
First Author: Yang S
Year: 2022
Journal: Diabetologia
Title: MicroRNA-193b impairs muscle growth in mouse models of type 2 diabetes by targeting the PDK1/Akt signalling pathway.
Volume: 65
Issue: 3
Pages: 563-581
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12438645 | J:125584
First Author: Picard F
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Progesterone receptor knockout mice have an improved glucose homeostasis secondary to beta -cell proliferation.
Volume: 99
Issue: 24
Pages: 15644-8
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19666844 | J:154217
First Author: Yang J
Year: 2009
Journal: Am J Physiol Heart Circ Physiol
Title: Role of MCP-1 in tumor necrosis factor-alpha-induced endothelial dysfunction in type 2 diabetic mice.
Volume: 297
Issue: 4
Pages: H1208-16
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Publication
20829391 | J:182821
First Author: Soeda Y
Year: 2010
Journal: Mol Endocrinol
Title: The inositol phosphatase SHIP2 negatively regulates insulin/IGF-I actions implicated in neuroprotection and memory function in mouse brain.
Volume: 24
Issue: 10
Pages: 1965-77
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Publication
26941017 | J:246383
First Author: Reddy MA
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Regulation of Vascular Smooth Muscle Cell Dysfunction Under Diabetic Conditions by miR-504.
Volume: 36
Issue: 5
Pages: 864-73
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Publication
31738412 | J:313801
First Author: Samidurai A
Year: 2020
Journal: Cardiovasc Res
Title: STAT3-miR-17/20 signalling axis plays a critical role in attenuating myocardial infarction following rapamycin treatment in diabetic mice.
Volume: 116
Issue: 13
Pages: 2103-2115
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19734360 | J:154317
First Author: Sartoretto JL
Year: 2009
Journal: Am J Physiol Heart Circ Physiol
Title: Regulation of VASP phosphorylation in cardiac myocytes: differential regulation by cyclic nucleotides and modulation of protein expression in diabetic and hypertrophic heart.
Volume: 297
Issue: 5
Pages: H1697-710
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Publication
23736543 | J:203210
First Author: Nakahara K
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Characterization of a novel genetically obese mouse model demonstrating early onset hyperphagia and hyperleptinemia.
Volume: 305
Issue: 3
Pages: E451-63
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Publication
30024858 | J:266922
First Author: Liles JT
Year: 2018
Journal: J Clin Invest
Title: ASK1 contributes to fibrosis and dysfunction in models of kidney disease.
Volume: 128
Issue: 10
Pages: 4485-4500
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Publication
35586340 | J:355366
 
First Author: Pelletier RM
Year: 2022
Journal: Front Cell Dev Biol
Title: PCSK9 Contributes to the Cholesterol, Glucose, and Insulin2 Homeostasis in Seminiferous Tubules and Maintenance of Immunotolerance in Testis.
Volume: 10
Pages: 889972
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17347480 | J:133914
First Author: Zhang LL
Year: 2007
Journal: Circ Res
Title: Activation of transient receptor potential vanilloid type-1 channel prevents adipogenesis and obesity.
Volume: 100
Issue: 7
Pages: 1063-70
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Publication
26769046 | J:246378
First Author: Hu W
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Bone Morphogenic Protein 4-Smad-Induced Upregulation of Platelet-Derived Growth Factor AA Impairs Endothelial Function.
Volume: 36
Issue: 3
Pages: 553-60
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Publication
19651810 | J:154390
First Author: Su D
Year: 2009
Journal: Diabetes
Title: FoxO1 links insulin resistance to proinflammatory cytokine IL-1beta production in macrophages.
Volume: 58
Issue: 11
Pages: 2624-33
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15793261 | J:109430
First Author: Davis RC
Year: 2005
Journal: Diabetes
Title: Ultrafine mapping of SNPs from mouse strains C57BL/6J, DBA/2J, and C57BLKS/J for loci contributing to diabetes and atherosclerosis susceptibility.
Volume: 54
Issue: 4
Pages: 1191-9
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Publication
21521693 | J:174820
First Author: Flach RJ
Year: 2011
Journal: J Biol Chem
Title: Loss of mitogen-activated protein kinase phosphatase-1 protects from hepatic steatosis by repression of cell death-inducing DNA fragmentation factor A (DFFA)-like effector C (CIDEC)/fat-specific protein 27.
Volume: 286
Issue: 25
Pages: 22195-202
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Publication
21586559 | J:174883
First Author: Peier AM
Year: 2011
Journal: Endocrinology
Title: Effects of peripherally administered neuromedin U on energy and glucose homeostasis.
Volume: 152
Issue: 7
Pages: 2644-54
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Publication
38582490 | J:347881
 
First Author: Pan X
Year: 2024
Journal: Metabolism
Title: Krüppel-like factor 10 protects against metabolic dysfunction-associated steatohepatitis by regulating HNF4α-mediated metabolic pathways.
Volume: 155
Pages: 155909
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Publication
25264246 | J:215526
First Author: Kim-Muller JY
Year: 2014
Journal: Cell Metab
Title: Metabolic inflexibility impairs insulin secretion and results in MODY-like diabetes in triple FoxO-deficient mice.
Volume: 20
Issue: 4
Pages: 593-602
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Publication
23715558 | J:219478
First Author: Velmurugan GV
Year: 2013
Journal: Cardiovasc Res
Title: Defective Nrf2-dependent redox signalling contributes to microvascular dysfunction in type 2 diabetes.
Volume: 100
Issue: 1
Pages: 143-50
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Publication
38538784 | J:349903
First Author: Lu YZ
Year: 2024
Journal: Nature
Title: CGRP sensory neurons promote tissue healing via neutrophils and macrophages.
Volume: 628
Issue: 8008
Pages: 604-611
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Publication
24916066 | J:310292
 
First Author: Niedowicz DM
Year: 2014
Journal: Acta Neuropathol Commun
Title: Obesity and diabetes cause cognitive dysfunction in the absence of accelerated β-amyloid deposition in a novel murine model of mixed or vascular dementia.
Volume: 2
Pages: 64
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Publication
37989315 | J:347516
First Author: Sundaram VK
Year: 2023
Journal: Cell Metab
Title: Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration.
Volume: 35
Issue: 12
Pages: 2136-2152.e9
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Publication
25576055 | J:249436
First Author: Chen Y
Year: 2015
Journal: Diabetes
Title: Enhancement of hypothalamic STAT3 acetylation by nuclear receptor Nur77 dictates leptin sensitivity.
Volume: 64
Issue: 6
Pages: 2069-81
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Publication
26483413 | J:235828
First Author: Ijuin T
Year: 2016
Journal: Mol Cell Biol
Title: Phosphatidylinositol 3,4,5-Trisphosphate Phosphatase SKIP Links Endoplasmic Reticulum Stress in Skeletal Muscle to Insulin Resistance.
Volume: 36
Issue: 1
Pages: 108-18
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Publication
33237428 | J:355607
First Author: Hegyi B
Year: 2020
Journal: Basic Res Cardiol
Title: Hyperglycemia regulates cardiac K(+) channels via O-GlcNAc-CaMKII and NOX2-ROS-PKC pathways.
Volume: 115
Issue: 6
Pages: 71
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Publication
30243722 | J:270296
First Author: Xu L
Year: 2018
Journal: Biochem Biophys Res Commun
Title: DNA-binding activity of STAT3 increased in hypothalamus of DIO mice; the reduction of STAT3 phosphorylation may facilitate leptin signaling.
Volume: 505
Issue: 1
Pages: 229-235
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Publication
34675215 | J:316739
First Author: Qin Y
Year: 2021
Journal: Nat Commun
Title: Macrophage deletion of Noc4l triggers endosomal TLR4/TRIF signal and leads to insulin resistance.
Volume: 12
Issue: 1
Pages: 6121
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Publication
26470784 | J:246551
First Author: Ni R
Year: 2016
Journal: Diabetes
Title: Mitochondrial Calpain-1 Disrupts ATP Synthase and Induces Superoxide Generation in Type 1 Diabetic Hearts: A Novel Mechanism Contributing to Diabetic Cardiomyopathy.
Volume: 65
Issue: 1
Pages: 255-68
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Publication
27039902 | J:235869
First Author: Bensellam M
Year: 2016
Journal: Diabetologia
Title: Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells.
Volume: 59
Issue: 7
Pages: 1492-1502
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Publication
19202066 | J:146455
First Author: Kawauchi K
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Loss of p53 enhances catalytic activity of IKKbeta through O-linked beta-N-acetyl glucosamine modification.
Volume: 106
Issue: 9
Pages: 3431-6
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Publication
25205222 | J:219690
First Author: Kim DK
Year: 2014
Journal: Diabetologia
Title: PKB/Akt phosphorylation of ERRγ contributes to insulin-mediated inhibition of hepatic gluconeogenesis.
Volume: 57
Issue: 12
Pages: 2576-85
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Publication
34622154 | J:314446
First Author: Yau B
Year: 2021
Journal: iScience
Title: Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet.
Volume: 24
Issue: 10
Pages: 103099
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16716264 | J:109651
First Author: Oh KS
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Liver PPARalpha and UCP2 are involved in the regulation of obesity and lipid metabolism by swim training in genetically obese db/db mice.
Volume: 345
Issue: 3
Pages: 1232-9
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18971923 | J:162711
First Author: Ijaz A
Year: 2009
Journal: Kidney Int
Title: Inhibition of C-jun N-terminal kinase improves insulin sensitivity but worsens albuminuria in experimental diabetes.
Volume: 75
Issue: 4
Pages: 381-8
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Publication
25485909 | J:227947
First Author: Finan B
Year: 2015
Journal: Nat Med
Title: A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents.
Volume: 21
Issue: 1
Pages: 27-36
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17267571 | J:117904
First Author: Johnson DR
Year: 2007
Journal: J Neurosci
Title: Acute hypoxia activates the neuroimmune system, which diabetes exacerbates.
Volume: 27
Issue: 5
Pages: 1161-6
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22581287 | J:187458
First Author: Sheng L
Year: 2012
Journal: Nat Med
Title: NF-κB–inducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon action.
Volume: 18
Issue: 6
Pages: 943-9
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Publication
22124464 | J:191536
First Author: Kimura K
Year: 2012
Journal: Diabetes
Title: Endoplasmic reticulum stress inhibits STAT3-dependent suppression of hepatic gluconeogenesis via dephosphorylation and deacetylation.
Volume: 61
Issue: 1
Pages: 61-73
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Publication
15820311 | J:97535
First Author: Yaguchi H
Year: 2005
Journal: Genomics
Title: Identification of candidate genes in the type 2 diabetes modifier locus using expression QTL.
Volume: 85
Issue: 5
Pages: 591-9
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26552046 | J:228070
First Author: Dominguez Rieg JA
Year: 2016
Journal: Lab Invest
Title: Regulation of intestinal SGLT1 by catestatin in hyperleptinemic type 2 diabetic mice.
Volume: 96
Issue: 1
Pages: 98-111
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24813890 | J:211797
First Author: Gonçalves GH
Year: 2014
Journal: Cell Rep
Title: Hypothalamic agouti-related peptide neurons and the central melanocortin system are crucial mediators of leptin's antidiabetic actions.
Volume: 7
Issue: 4
Pages: 1093-103
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Publication
11713466 | J:109860
First Author: Gonzalez A
Year: 2001
Journal: Nat Immunol
Title: Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes.
Volume: 2
Issue: 12
Pages: 1117-25
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Publication
21737546 | J:179350
First Author: Cheng H
Year: 2011
Journal: J Am Soc Nephrol
Title: Podocyte COX-2 exacerbates diabetic nephropathy by increasing podocyte (pro)renin receptor expression.
Volume: 22
Issue: 7
Pages: 1240-51
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Publication
27044864 | J:236187
First Author: Uruno A
Year: 2016
Journal: Mol Cell Biol
Title: Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism.
Volume: 36
Issue: 11
Pages: 1655-72
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Publication
38630048 | J:358643
First Author: Stickel KC
Year: 2024
Journal: Am J Physiol Endocrinol Metab
Title: Mechanisms of spinophilin-dependent pancreas dysregulation in obesity.
Volume: 327
Issue: 2
Pages: E155-E171
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Publication
27358174 | J:249807
First Author: Arab JP
Year: 2017
Journal: Hepatology
Title: Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives.
Volume: 65
Issue: 1
Pages: 350-362
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16339484 | J:118064
First Author: Barouch LA
Year: 2006
Journal: Circ Res
Title: Cardiac myocyte apoptosis is associated with increased DNA damage and decreased survival in murine models of obesity.
Volume: 98
Issue: 1
Pages: 119-24
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17202326 | J:142637
First Author: Sherry CL
Year: 2007
Journal: J Immunol
Title: Augmented lipopolysaccharide-induced TNF-alpha production by peritoneal macrophages in type 2 diabetic mice is dependent on elevated glucose and requires p38 MAPK.
Volume: 178
Issue: 2
Pages: 663-70
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19363130 | J:150876
First Author: Yang J
Year: 2009
Journal: Am J Physiol Heart Circ Physiol
Title: Feed-forward signaling of TNF-alpha and NF-kappaB via IKK-beta pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice.
Volume: 296
Issue: 6
Pages: H1850-8
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31150422 | J:276464
First Author: Sakurai A
Year: 2019
Journal: PLoS One
Title: Involvement of Elf3 on Smad3 activation-dependent injuries in podocytes and excretion of urinary exosome in diabetic nephropathy.
Volume: 14
Issue: 5
Pages: e0216788
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Publication
33456576 | J:331219
First Author: Sheng J
Year: 2021
Journal: Theranostics
Title: Smad3 deficiency promotes beta cell proliferation and function in db/db mice via restoring Pax6 expression.
Volume: 11
Issue: 6
Pages: 2845-2859
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Publication
24394757 | J:211951
First Author: Crépin D
Year: 2014
Journal: Mol Cell Endocrinol
Title: The over-expression of miR-200a in the hypothalamus of ob/ob mice is linked to leptin and insulin signaling impairment.
Volume: 384
Issue: 1-2
Pages: 1-11
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Publication
29089371 | J:292948
First Author: Wang XX
Year: 2018
Journal: J Am Soc Nephrol
Title: FXR/TGR5 Dual Agonist Prevents Progression of Nephropathy in Diabetes and Obesity.
Volume: 29
Issue: 1
Pages: 118-137
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Publication
27528615 | J:236304
First Author: Chen Q
Year: 2016
Journal: Mol Cell Biol
Title: Functional Differences of Very-Low-Density Lipoprotein Receptor Splice Variants in Regulating Wnt Signaling.
Volume: 36
Issue: 20
Pages: 2645-54
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Publication
16794074 | J:110012
First Author: Qi L
Year: 2006
Journal: Science
Title: TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism.
Volume: 312
Issue: 5781
Pages: 1763-6
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Publication
27932386 | J:247019
First Author: Liu B
Year: 2017
Journal: Diabetes
Title: Aberrant Expression of FBXO2 Disrupts Glucose Homeostasis Through Ubiquitin-Mediated Degradation of Insulin Receptor in Obese Mice.
Volume: 66
Issue: 3
Pages: 689-698
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Publication
26340929 | J:247018
First Author: Lee JM
Year: 2016
Journal: Diabetes
Title: Insulin-Inducible SMILE Inhibits Hepatic Gluconeogenesis.
Volume: 65
Issue: 1
Pages: 62-73
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Publication
31296846 | J:285944
First Author: Pham DD
Year: 2019
Journal: Cell Death Dis
Title: Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells.
Volume: 10
Issue: 7
Pages: 537
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Publication
25658689 | J:242398
First Author: Pourhoseini S
Year: 2015
Journal: PLoS One
Title: Upregulation of miR21 and repression of Grhl3 by leptin mediates sinusoidal endothelial injury in experimental nonalcoholic steatohepatitis.
Volume: 10
Issue: 2
Pages: e0116780
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Publication
30171034 | J:265187
 
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