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Search results 2601 to 2700 out of 3085 for Myd88

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Protein Coding Gene
MGI:1346347 | Mapk7
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1346870 | Map2k6
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1346861 | Mapk8
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1913763 | Tab1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1338024 | Mapk11
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:88059 | App
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1342290 | Rps6ka2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1099800 | Nfkb2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:101835 | Traf2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1913839 | Ube2v1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1891456 | Ripk2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1346877 | Map3k7
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:104558 | Rps6ka1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:104752 | Nfkbib
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:107420 | Irak1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1913974 | Tab3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:104557 | Rps6ka3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q60778
Organism: Mus musculus/domesticus
Length: 359  
Fragment?: false
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Protein
P49138
Organism: Mus musculus/domesticus
Length: 386  
Fragment?: false
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Protein
P18654
Organism: Mus musculus/domesticus
Length: 740  
Fragment?: false
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Protein
Q9WUI1
Organism: Mus musculus/domesticus
Length: 364  
Fragment?: false
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Protein
Q62073
Organism: Mus musculus/domesticus
Length: 579  
Fragment?: false
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Protein
Q91Y86
Organism: Mus musculus/domesticus
Length: 384  
Fragment?: false
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Protein
Q9WUT3
Organism: Mus musculus/domesticus
Length: 733  
Fragment?: false
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Protein
P18653
Organism: Mus musculus/domesticus
Length: 724  
Fragment?: false
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Protein
Q5SRY7
Organism: Mus musculus/domesticus
Length: 542  
Fragment?: false
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Protein
O89110
Organism: Mus musculus/domesticus
Length: 480  
Fragment?: false
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Protein
Q01147
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
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Protein
P70236
Organism: Mus musculus/domesticus
Length: 334  
Fragment?: false
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Protein
Q9WVS8
Organism: Mus musculus/domesticus
Length: 806  
Fragment?: false
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Protein
Q571K4
Organism: Mus musculus/domesticus
Length: 716  
Fragment?: false
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Protein
Q8CF89
Organism: Mus musculus/domesticus
Length: 502  
Fragment?: false
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Protein
Q99K90
Organism: Mus musculus/domesticus
Length: 693  
Fragment?: false
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Protein
P12023
Organism: Mus musculus/domesticus
Length: 770  
Fragment?: false
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Protein
Q9CZY3
Organism: Mus musculus/domesticus
Length: 147  
Fragment?: false
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Protein
P58801
Organism: Mus musculus/domesticus
Length: 539  
Fragment?: false
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Protein
P39429
Organism: Mus musculus/domesticus
Length: 501  
Fragment?: false
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Strain
MGI:3809701 | B6.Cg-Myd88<tm1Defr> Tg(Itgax-cre)1-1Reiz
Attribute String: congenic, targeted mutation, transgenic
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Genotype
Genotype
Symbol: Myd88/Myd88 Tg(Itgax-cre)1-1Reiz/?
Background: B6.Cg-Myd88 Tg(Itgax-cre)1-1Reiz
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Myd88/Myd88 Tg(Vil1-cre)997Gum/?
Background: involves: 129P2/OlaHsd * C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Myd88/Myd88 Tnip1/Tnip1 Tg(Itgax-cre)1-1Reiz/?
Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lyn/Lyn Myd88/Myd88 Tg(Itgax-cre)1-1Reiz/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Myd88/Myd88 Tg(Ccl19-cre)489Biat/?
Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Myd88/Myd88 Nkx3-2/Nkx3-2<+>
Background: involves: 129 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Publication
10426995 | -
First Author: Brightbill HD
Year: 1999
Journal: Science
Title: Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors.
Volume: 285
Issue: 5428
Pages: 732-6
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Publication
12150927 | J:78189
First Author: Kobayashi K
Year: 2002
Journal: Cell
Title: IRAK-M is a negative regulator of Toll-like receptor signaling.
Volume: 110
Issue: 2
Pages: 191-202
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Publication
30332431 | J:266821
First Author: Dong D
Year: 2018
Journal: PLoS One
Title: GPR108, an NF-κB activator suppressed by TIRAP, negatively regulates TLR-triggered immune responses.
Volume: 13
Issue: 10
Pages: e0205303
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Publication
11607032 | J:72167
First Author: Alexopoulou L
Year: 2001
Journal: Nature
Title: Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3.
Volume: 413
Issue: 6857
Pages: 732-8
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Publication
25736436 | J:224712
First Author: Hu YH
Year: 2015
Journal: EMBO Rep
Title: WDFY1 mediates TLR3/4 signaling by recruiting TRIF.
Volume: 16
Issue: 4
Pages: 447-55
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Publication
17486091 | J:122395
First Author: Pathak SK
Year: 2007
Journal: Nat Immunol
Title: Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages.
Volume: 8
Issue: 6
Pages: 610-8
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Publication
14556004 | J:86256
First Author: Yamamoto M
Year: 2003
Journal: Nat Immunol
Title: TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway.
Volume: 4
Issue: 11
Pages: 1144-50
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Publication
22312129 | J:181861
First Author: De Arras L
Year: 2012
Journal: J Immunol
Title: Spatiotemporal inhibition of innate immunity signaling by the Tbc1d23 RAB-GAP.
Volume: 188
Issue: 6
Pages: 2905-13
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Publication
16757566 | J:111048
First Author: McGettrick AF
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling.
Volume: 103
Issue: 24
Pages: 9196-201
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Publication
12471095 | J:341401
First Author: Yamamoto M
Year: 2002
Journal: J Immunol
Title: Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling.
Volume: 169
Issue: 12
Pages: 6668-72
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Publication
32191633 | J:338775
First Author: Tilstra JS
Year: 2020
Journal: J Clin Invest
Title: B cell-intrinsic TLR9 expression is protective in murine lupus.
Volume: 130
Issue: 6
Pages: 3172-3187
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Publication
21037088 | J:166145
First Author: Ribot JC
Year: 2010
Journal: J Immunol
Title: Cutting edge: adaptive versus innate receptor signals selectively control the pool sizes of murine IFN-γ- or IL-17-producing γδ T cells upon infection.
Volume: 185
Issue: 11
Pages: 6421-6425
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Publication
19946272 | J:158464
First Author: Sheedy FJ
Year: 2010
Journal: Nat Immunol
Title: Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21.
Volume: 11
Issue: 2
Pages: 141-7
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Publication
18190779 | J:131296
First Author: Rekhter M
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Genetic ablation of IRAK4 kinase activity inhibits vascular lesion formation.
Volume: 367
Issue: 3
Pages: 642-8
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Publication
28137874 | J:240936
First Author: Choi JH
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice.
Volume: 114
Issue: 7
Pages: E1196-E1204
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Publication
28552327 | J:242566
First Author: Lionakis MS
Year: 2017
Journal: Cancer Cell
Title: Inhibition of B Cell Receptor Signaling by Ibrutinib in Primary CNS Lymphoma.
Volume: 31
Issue: 6
Pages: 833-843.e5
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Publication
19050234 | J:142082
First Author: Eigenbrod T
Year: 2008
Journal: J Immunol
Title: Cutting edge: critical role for mesothelial cells in necrosis-induced inflammation through the recognition of IL-1 alpha released from dying cells.
Volume: 181
Issue: 12
Pages: 8194-8
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Publication
21248260 | J:169140
First Author: Andris F
Year: 2011
Journal: J Immunol
Title: Metabolic stress boosts humoral responses in vivo independently of inflammasome and inflammatory reaction.
Volume: 186
Issue: 4
Pages: 2245-53
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Publication
17273999 | J:117901
First Author: Schmitz F
Year: 2007
Journal: Eur J Immunol
Title: Interferon-regulatory-factor 1 controls Toll-like receptor 9-mediated IFN-beta production in myeloid dendritic cells.
Volume: 37
Issue: 2
Pages: 315-27
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Publication
16604075 | J:112559
First Author: Shinohara ML
Year: 2006
Journal: Nat Immunol
Title: Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells.
Volume: 7
Issue: 5
Pages: 498-506
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Publication
17004992 | J:135842
First Author: Albiger B
Year: 2007
Journal: Cell Microbiol
Title: Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection.
Volume: 9
Issue: 3
Pages: 633-44
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Publication
21646294 | J:176180
First Author: Wang S
Year: 2011
Journal: J Immunol
Title: MyD88-dependent TLR1/2 signals educate dendritic cells with gut-specific imprinting properties.
Volume: 187
Issue: 1
Pages: 141-50
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Publication
35769880 | J:359993
First Author: Chen F
Year: 2022
Journal: iScience
Title: The STING1-MYD88 complex drives ACOD1/IRG1 expression and function in lethal innate immunity.
Volume: 25
Issue: 7
Pages: 104561
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Publication
38697117 | J:348311
First Author: Gitlin AD
Year: 2024
Journal: Immunity
Title: N4BP1 coordinates ubiquitin-dependent crosstalk within the IκB kinase family to limit Toll-like receptor signaling and inflammation.
Volume: 57
Issue: 5
Pages: 973-986.e7
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Publication
32438408 | J:294933
 
First Author: Lim TJF
Year: 2020
Journal: J Exp Med
Title: Talin1 controls dendritic cell activation by regulating TLR complex assembly and signaling.
Volume: 217
Issue: 8
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Publication
32133012 | J:307557
 
First Author: Miao Y
Year: 2020
Journal: Front Immunol
Title: BCAP Regulates Dendritic Cell Maturation Through the Dual-Regulation of NF-κB and PI3K/AKT Signaling During Infection.
Volume: 11
Pages: 250
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Publication
24696448 | J:229884
First Author: Tan Q
Year: 2014
Journal: Diabetes
Title: IRAK-M deficiency promotes the development of type 1 diabetes in NOD mice.
Volume: 63
Issue: 8
Pages: 2761-75
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Publication
38367238 | J:347749
First Author: Pereira M
Year: 2024
Journal: Cell Rep
Title: The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection.
Volume: 43
Issue: 2
Pages: 113795
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Publication
28701369 | J:244451
First Author: Wang JQ
Year: 2017
Journal: J Exp Med
Title: Synergistic cooperation and crosstalk between MYD88L265P and mutations that dysregulate CD79B and surface IgM.
Volume: 214
Issue: 9
Pages: 2759-2776
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Publication
15004556 | J:89209
First Author: Brint EK
Year: 2004
Journal: Nat Immunol
Title: ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance.
Volume: 5
Issue: 4
Pages: 373-9
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Publication
18758466 | J:140990
First Author: Cao W
Year: 2008
Journal: Nat Immunol
Title: Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway.
Volume: 9
Issue: 10
Pages: 1157-64
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Publication
35857476 | J:327552
First Author: Tawaratsumida K
Year: 2022
Journal: Sci Adv
Title: A phospho-tyrosine-based signaling module using SPOP, CSK, and LYN controls TLR-induced IRF activity.
Volume: 8
Issue: 27
Pages: eabq0084
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Publication
35963236 | J:328359
First Author: Ryu S
Year: 2022
Journal: Immunity
Title: The matricellular protein SPARC induces inflammatory interferon-response in macrophages during aging.
Volume: 55
Issue: 9
Pages: 1609-1626.e7
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Publication
35044826 | J:319632
First Author: Rodriguez S
Year: 2022
Journal: Sci Adv
Title: Preneoplastic somatic mutations including MYD88L265P in lymphoplasmacytic lymphoma.
Volume: 8
Issue: 3
Pages: eabl4644
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Publication
16365431 | J:126269
First Author: Sekine Y
Year: 2006
Journal: J Immunol
Title: Modulation of TLR4 signaling by a novel adaptor protein signal-transducing adaptor protein-2 in macrophages.
Volume: 176
Issue: 1
Pages: 380-9
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Publication
34508096 | J:314207
First Author: Dutta D
Year: 2021
Journal: Nat Commun
Title: Selective targeting of the TLR2/MyD88/NF-κB pathway reduces α-synuclein spreading in vitro and in vivo.
Volume: 12
Issue: 1
Pages: 5382
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Publication
19272591 | J:148548
First Author: Vecchiarelli A
Year: 2009
Journal: Cell Immunol
Title: The GITRL-GITR system alters TLR-4 expression on DC during fungal infection.
Volume: 257
Issue: 1-2
Pages: 13-22
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Publication
31273097 | J:276778
 
First Author: Abdel-Nour M
Year: 2019
Journal: Science
Title: The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling.
Volume: 365
Issue: 6448
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Publication
20083674 | J:159476
First Author: Martino A
Year: 2010
Journal: J Immunol
Title: Mycobacterium bovis bacillus Calmette-Guérin vaccination mobilizes innate myeloid-derived suppressor cells restraining in vivo T cell priming via IL-1R-dependent nitric oxide production.
Volume: 184
Issue: 4
Pages: 2038-47
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Publication
26173179 | J:226080
 
First Author: Ito A
Year: 2015
Journal: Elife
Title: LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling.
Volume: 4
Pages: e08009
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Publication
30842236 | J:275201
First Author: Zhu C
Year: 2019
Journal: J Exp Med
Title: SARM1 deficiency up-regulates XAF1, promotes neuronal apoptosis, and accelerates prion disease.
Volume: 216
Issue: 4
Pages: 743-756
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Publication
36172386 | J:336030
 
First Author: Loh JT
Year: 2022
Journal: Front Immunol
Title: Dok3 restrains neutrophil production of calprotectin during TLR4 sensing of SARS-CoV-2 spike protein.
Volume: 13
Pages: 996637
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Publication
21829704 | J:263374
First Author: Sakaguchi M
Year: 2011
Journal: PLoS One
Title: TIRAP, an adaptor protein for TLR2/4, transduces a signal from RAGE phosphorylated upon ligand binding.
Volume: 6
Issue: 8
Pages: e23132
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Publication
15064760 | J:89807
First Author: Meylan E
Year: 2004
Journal: Nat Immunol
Title: RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation.
Volume: 5
Issue: 5
Pages: 503-7
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Publication
17512498 | J:122454
First Author: Ikeda O
Year: 2007
Journal: Biochem Biophys Res Commun
Title: STAP-2 regulates c-Fms/M-CSF receptor signaling in murine macrophage Raw 264.7 cells.
Volume: 358
Issue: 3
Pages: 931-7
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Publication
16424162 | J:126432
First Author: Wang T
Year: 2006
Journal: J Immunol
Title: Flightless I homolog negatively modulates the TLR pathway.
Volume: 176
Issue: 3
Pages: 1355-62
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Publication
18222170 | J:136811
First Author: Tanimura N
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signaling.
Volume: 368
Issue: 1
Pages: 94-9
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Publication
19535142 | J:151719
First Author: Tross D
Year: 2009
Journal: Mol Immunol
Title: Global changes in gene expression and synergistic interactions induced by TLR9 and TLR3.
Volume: 46
Issue: 13
Pages: 2557-64
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Publication
26322579 | J:228919
First Author: Liu X
Year: 2015
Journal: Nat Med
Title: CD47 blockade triggers T cell-mediated destruction of immunogenic tumors.
Volume: 21
Issue: 10
Pages: 1209-15
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Publication
27311859 | J:236490
First Author: Li W
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Brucella TIR-like protein TcpB/Btp1 specifically targets the host adaptor protein MAL/TIRAP to promote infection.
Volume: 477
Issue: 3
Pages: 509-14
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Publication
27780729 | J:240806
First Author: Yang Y
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Looped limulus anti-lipopolysaccharide derived peptide CLP-19 induces endotoxin tolerance involved inhibition of NF-κB activation.
Volume: 480
Issue: 3
Pages: 486-491
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Publication
30630901 | J:295155
 
First Author: Akilesh HM
Year: 2019
Journal: Science
Title: Chronic TLR7 and TLR9 signaling drives anemia via differentiation of specialized hemophagocytes.
Volume: 363
Issue: 6423
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Publication
32778760 | J:301131
First Author: Zhou H
Year: 2020
Journal: Nat Immunol
Title: IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes.
Volume: 21
Issue: 10
Pages: 1219-1231
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Publication
39060650 | J:358400
First Author: Medhavy A
Year: 2024
Journal: Nat Immunol
Title: A TNIP1-driven systemic autoimmune disorder with elevated IgG4.
Volume: 25
Issue: 9
Pages: 1678-1691
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Protein Coding Gene
MGI:1934835 | Ube2n
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:104741 | Nfkbia
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom