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Search results 2601 to 2700 out of 2874 for Nes

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:7639665
Assay Type: RNA in situ
Annotation Date: 2024-05-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7639678
Age: embryonic day 14.5
Note: Expression in Nes expressing zones, relatively dispersed throughout ventricular zone and subventricular zone in cortex.
Specimen Label: 3e
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
 
Probe: MGI:7639665
Assay Type: RNA in situ
Annotation Date: 2024-05-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7639678
Age: embryonic day 12.5
Note: Expression in Nes expressing zones, relatively dispersed throughout ventricular zone and subventricular zone in cganglionic eminence.
Specimen Label: 3c
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
 
Probe: MGI:7639665
Assay Type: RNA in situ
Annotation Date: 2024-05-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7639678
Age: embryonic day 14.5
Note: Expression in Nes expressing zones, relatively dispersed throughout ventricular zone and subventricular zone in ganglionic eminence.
Specimen Label: 3f
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
 
Probe: MGI:7545541
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7545551
Age: embryonic day 14.0
Note: Expression co-localized with Nes in neural stem cells in ventricular zone.
Specimen Label: 2C TOX3 (lower)
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6436314
Assay Type: Immunohistochemistry
Annotation Date: 2020-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3671628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6436562
Age: postnatal adult
Image: 3D
Note: Co-localization of expression with Nes within subventricular zone of lateral ventricles.
Specimen Label: 3D
Detected: true
Specimen Num: 18
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Publication
31439353 | J:294126
 
First Author: Egaña-Gorroño L
Year: 2019
Journal: Atherosclerosis
Title: Allograft inflammatory factor-1 supports macrophage survival and efferocytosis and limits necrosis in atherosclerotic plaques.
Volume: 289
Pages: 184-194
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Publication
28302627 | J:263668
First Author: Riascos-Bernal DF
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Inhibition of Smooth Muscle β-Catenin Hinders Neointima Formation After Vascular Injury.
Volume: 37
Issue: 5
Pages: 879-888
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GXD Expression
GXD Expression
 
Probe: MGI:7258504
Assay Type: Immunohistochemistry
Annotation Date: 2022-04-05
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3270420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7259771
Age: embryonic day 12.0
Note: Predominately cytoplasmic with a small amount of nuclear expression. Co-expressed with Nes in cell bodies of neural precursor cells.
Specimen Label: 3Aiii-vii
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7258504
Assay Type: Immunohistochemistry
Annotation Date: 2022-04-05
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3270426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7259771
Age: embryonic day 18.0
Note: Predominately cytoplasmic with a small amount of nuclear expression. Co-expressed with Nes in cell bodies of neural precursor cells.
Specimen Label: 3Biii-vii
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7258504
Assay Type: Immunohistochemistry
Annotation Date: 2022-04-05
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7259771
Age: embryonic day 12.0
Note: Predominately cytoplasmic with a small amount of nuclear expression. Co-expressed with Nes in cell bodies of neural precursor cells.
Specimen Label: 3Aiii-vii
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7258504
Assay Type: Immunohistochemistry
Annotation Date: 2022-04-05
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7259771
Age: embryonic day 18.0
Note: Predominately cytoplasmic with a small amount of nuclear expression. Co-expressed with Nes in cell bodies of neural precursor cells.
Specimen Label: 3Biii-vii
Detected: true
Specimen Num: 3
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Publication
31914850 | J:307032
First Author: Becher T
Year: 2020
Journal: Circ Res
Title: Three-Dimensional Imaging Provides Detailed Atherosclerotic Plaque Morphology and Reveals Angiogenesis After Carotid Artery Ligation.
Volume: 126
Issue: 5
Pages: 619-632
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Publication
38478616 | J:360920
First Author: Oliveira-Paula GH
Year: 2024
Journal: Sci Adv
Title: The β-catenin C terminus links Wnt and sphingosine-1-phosphate signaling pathways to promote vascular remodeling and atherosclerosis.
Volume: 10
Issue: 11
Pages: eadg9278
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Allele
Tg(Nes-cre)2472Pick | MGI:3528493
Name: transgene insertion 2472, David J Picketts
Allele Type: Transgenic
Attribute String: Recombinase
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GXD Expression
GXD Expression
 
Probe: MGI:6432319
Assay Type: Immunohistochemistry
Annotation Date: 2020-06-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6432399
Age: embryonic day 14.5
Note: Most prominent expression. Expressed in radially oriented processes. Colocalized with Nes in radial glial processes. Strong expression in tangentially oriented axonal processes.
Specimen Label: 1B/D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757926
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7488687
Age: embryonic day 18.5
Note: Coexpressed with Nes in a subset of cells with small narrow nuclei. LacZ positive cells in the medial and lateral ventral columns did not express glial marker Nes.
Specimen Label: not shown
Detected: true
Specimen Num: 32
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GO Term
GO:0042565 | RNA nuclear export complex
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Genotype
Genotype
Symbol: Nes/Nes<+> Srsf10/Srsf10
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
19853565 | J:154781
First Author: Young T
Year: 2009
Journal: Dev Cell
Title: Cdx and Hox genes differentially regulate posterior axial growth in mammalian embryos.
Volume: 17
Issue: 4
Pages: 516-26
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Publication
25651181 | J:219777
First Author: Santori FR
Year: 2015
Journal: Cell Metab
Title: Identification of natural RORγ ligands that regulate the development of lymphoid cells.
Volume: 21
Issue: 2
Pages: 286-97
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Publication
36596796 | J:351490
First Author: Chinnasamy P
Year: 2023
Journal: Nat Commun
Title: Increased adipose catecholamine levels and protection from obesity with loss of Allograft Inflammatory Factor-1.
Volume: 14
Issue: 1
Pages: 38
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Publication
28526706 | J:244257
First Author: Dal-Secco D
Year: 2017
Journal: Am J Physiol Heart Circ Physiol
Title: Cardiac hyporesponsiveness in severe sepsis is associated with nitric oxide-dependent activation of G protein receptor kinase.
Volume: 313
Issue: 1
Pages: H149-H163
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Allele
Tg(Nes-cre/ERT2)3Imayo | MGI:7520010
Name: transgene insertion 3, Itaru Imayoshi
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Allele
Tg(Nes-cre/ERT2)5-2Imayo | MGI:7520012
Name: transgene insertion 5-2, Itaru Imayoshi
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Allele
Tg(Nes-cre/ERT2)6Imayo | MGI:7520014
Name: transgene insertion 6, Itaru Imayoshi
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Publication
23359708 | -
First Author: Edwards JS
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Molecular basis of antibiotic multiresistance transfer in Staphylococcus aureus.
Volume: 110
Issue: 8
Pages: 2804-9
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Protein Domain
IPR040834 | NES_C_h
Type: Domain
Description: This domain is found in nicking enzyme in S. aureus. NES initiates and terminates the transfer of plasmids that variously confer resistance to a range of drugs, including vancomycin and gentamicin. This domain is found in the C-terminal region of NES. The C-terminal region is required for conjugation and significantly impacts the catalytic activity of the N-terminal relaxase [].
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Publication
23042116 | J:241988
First Author: Molenaar JJ
Year: 2012
Journal: Nat Genet
Title: LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression.
Volume: 44
Issue: 11
Pages: 1199-206
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Publication
38905335 | J:350094
First Author: Fredlund E
Year: 2024
Journal: Sci Adv
Title: MOXD1 is a lineage-specific gene and a tumor suppressor in neuroblastoma.
Volume: 10
Issue: 25
Pages: eado1583
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Allele
Tg(Nes-cre)1Wmz | MGI:2429684
Name: transgene insertion 1, Weimin Zhong
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Nes-CFP)1Enik | MGI:6368174
Name: transgene insertion 1, Grigori Enikolopov
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Nes-cre/ERT2)62.33Ics | MGI:7346222
Name: transgene insertion 62.33, Mouse Clinical Institute
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Strain
MGI:6146523 | C57BL/6-Tg(Nes-cre/ERT2)3Imayo/Imayo
Attribute String: mutant strain, coisogenic, transgenic
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Strain
MGI:6146526 | C57BL/6-Tg(Nes-cre/ERT2)5-2Imayo/Imayo
Attribute String: mutant strain, coisogenic, transgenic
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Strain
MGI:6146527 | C57BL/6-Tg(Nes-cre/ERT2)6Imayo/Imayo
Attribute String: mutant strain, coisogenic, transgenic
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Publication
15318225 | -
First Author: Wood MJ
Year: 2004
Journal: Nature
Title: Structural basis for redox regulation of Yap1 transcription factor localization.
Volume: 430
Issue: 7002
Pages: 917-21
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Publication
12466024 | -
 
First Author: Yi C
Year: 2002
Journal: BMC Cell Biol
Title: An initial biochemical and cell biological characterization of the mammalian homologue of a central plant developmental switch, COP1.
Volume: 3
Pages: 30
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Publication
27121162 | -
First Author: Sanchez-Barcelo EJ
Year: 2016
Journal: J Pineal Res
Title: Constitutive photomorphogenesis protein 1 (COP1) and COP9 signalosome, evolutionarily conserved photomorphogenic proteins as possible targets of melatonin.
Volume: 61
Issue: 1
Pages: 41-51
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Publication
21625211 | -
First Author: Choi HH
Year: 2011
Journal: Oncogene
Title: COP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σ.
Volume: 30
Issue: 48
Pages: 4791-801
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Protein Domain
IPR014877 | XPO1_C_dom
Type: Domain
Description: CRM1 (also known as exportin1) mediates the nuclear export of proteins bearing a leucine-rich nuclear export signal (NES). CRM1 forms a complex with the NES containing protein and the small GTPase Ran.This entry represents the C-terminal domain of CRM1. It forms an alpha helical structure formed by six helical hairpin motifs that are structurally similar to the HEAT repeat, but share little sequence similarity to the HEAT repeat [].
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Protein Domain
IPR042755 | COP1
Type: Family
Description: COP1 is a RING finger-type ubiquitin E3 ligase. In Arabidopsis, it is a central switch for the transition from plant growth underground in darkness (etiolation) to growth under light exposure (photomorphogenesis) []. In mammals, it functions as an E3 ubiquitin-protein ligase involved in tumorigenesis, gluconeogenesis, and lipid metabolism. It is regulated by the COP9 signalosome []and is involved in 14-3-3 delta ubiquitin-mediated degradation []. COP1 contains a classic leucine-rich NES and a novel bipartite NLS bridged by a RING finger domain [].
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Protein Domain
IPR023167 | Yap1_redox_dom_sf
Type: Homologous_superfamily
Description: The transcription factor Yap1 is a central regulator of the response to oxidative stress in Saccharomyces cerevisiae. In the active oxidized form, a nuclear export signal (NES) in the carboxy-terminal cysteine-rich domain is masked by disulphide-bond-mediated interactions with a conserved amino-terminal α-helix. Upon reduction of the disulphide bonds, Yap1 undergoes a change that exposes the NES and allows redistribution to the cytoplasm []. This entry represents a redox-regulated domain superfamily of Yap1.
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Publication
22357134 | J:196735
First Author: Malone CD
Year: 2012
Journal: Mol Cell Neurosci
Title: Mcl-1 regulates the survival of adult neural precursor cells.
Volume: 49
Issue: 4
Pages: 439-47
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Publication
36682400 | J:333042
 
First Author: Gillis HL
Year: 2023
Journal: Exp Neurol
Title: VGF is required for recovery after focal stroke.
Volume: 362
Pages: 114326
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Allele
Tg(Nes-cre/ERT2)5-1Imayo | MGI:3641212
Name: transgene insertion 5-1, Itaru Imayoshi
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Strain
MGI:6146525 | C57BL/6-Tg(Nes-cre/ERT2)5-1Imayo/Imayo
Attribute String: mutant strain, coisogenic, transgenic
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Strain
MGI:4839732 | C57BL/6-Tg(Nes-cre/ERT2)5-1Imayo
Attribute String: coisogenic, mutant strain, transgenic
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Allele
Tg(Nes-cre/ERT2)4Imayo | MGI:3817325
Name: transgene insertion 4, Itaru Imayoshi
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Allele
Tg(Nes-cre/ERT2)1Imayo | MGI:4398673
Name: transgene insertion 1, Itaru Imayoshi
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Allele
Tg(Nes-cre/ERT2)#Kag | MGI:4941327
Name: transgene insertion, Ryoichiro Kageyama
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Strain
MGI:6368176 | B6.Cg-Tg(Nes-CFP)1Enik/J
Attribute String: congenic, mutant strain, transgenic
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Publication
32645024 | J:294986
First Author: Surzenko N
Year: 2020
Journal: PLoS One
Title: Prenatal exposure to the probiotic Lactococcus lactis decreases anxiety-like behavior and modulates cortical cytoarchitecture in a sex specific manner.
Volume: 15
Issue: 7
Pages: e0223395
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Allele
Nes<em1(flpo)Awar> | MGI:6740241
Name: nestin; endonuclease-mediated mutation 1, Rajeshwar Awatramani
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, Recombinase, Reporter
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Strain
MGI:7381135 | B6N.FVB-Tg(Nes-cre/ERT2)62.33Ics/Ics
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Atrx/? Tg(Nes-cre)2472Pick/?
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mcl1/Mcl1 Tg(Nes-cre)2472Pick/?
Background: involves: 129X1/SvJ * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Casp8/Casp8 Tg(Nes-cre)1Wmz/?
Background: involves: 129 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctcf/Ctcf Tg(Nes-cre)2472Pick/?
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mcl1/Mcl1<+> Tg(Nes-cre)2472Pick/?
Background: involves: 129X1/SvJ * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pdpn/Pdpn Tg(Nes-cre)1Wmz/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Nes-cre/ERT2)5-1Imayo/?
Background: C57BL/6-Tg(Nes-cre/ERT2)5-1Imayo
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Nes-CFP)1Enik/?
Background: involves: C57BL/6J * Swiss Webster
Zygosity: ot
Has Mutant Allele: true
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Publication
16516211 | J:107641
First Author: Makita J
Year: 2006
Journal: FEBS Lett
Title: Identification of the nuclear export signal in the helix-loop-helix inhibitor Id1.
Volume: 580
Issue: 7
Pages: 1812-6
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Publication
26474641 | -
First Author: Srivastava AK
Year: 2015
Journal: Plant Physiol
Title: Short Hypocotyl in White Light1 Interacts with Elongated Hypocotyl5 (HY5) and Constitutive Photomorphogenic1 (COP1) and Promotes COP1-Mediated Degradation of HY5 during Arabidopsis Seedling Development.
Volume: 169
Issue: 4
Pages: 2922-34
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Publication
23824576 | J:198626
First Author: Hasan SM
Year: 2013
Journal: Development
Title: Mcl1 regulates the terminal mitosis of neural precursor cells in the mammalian brain through p27Kip1.
Volume: 140
Issue: 15
Pages: 3118-27
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Publication
19409266 | J:157364
First Author: Espinosa JS
Year: 2009
Journal: Neuron
Title: Uncoupling dendrite growth and patterning: single-cell knockout analysis of NMDA receptor 2B.
Volume: 62
Issue: 2
Pages: 205-17
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Publication
29453206 | J:261020
First Author: Gao A
Year: 2018
Journal: J Neurosci
Title: Elevation of Hippocampal Neurogenesis Induces a Temporally Graded Pattern of Forgetting of Contextual Fear Memories.
Volume: 38
Issue: 13
Pages: 3190-3198
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Publication
27665712 | J:283307
 
First Author: Fogarty LC
Year: 2016
Journal: Mol Cell Neurosci
Title: Bcl-xL dependency coincides with the onset of neurogenesis in the developing mammalian spinal cord.
Volume: 77
Pages: 34-46
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Publication
23027973 | J:190296
First Author: Onoguchi M
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: A noncoding RNA regulates the neurogenin1 gene locus during mouse neocortical development.
Volume: 109
Issue: 42
Pages: 16939-44
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Strain
MGI:7507231 | C57BL/6-Tg(Nes-cre/ERT2)4Imayo/Imayo
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:4839730 | C57BL/6-Tg(Nes-cre/ERT2)4Imayo
Attribute String: coisogenic, mutant strain, transgenic
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Publication
32850819 | J:302847
 
First Author: Chen GY
Year: 2020
Journal: Front Cell Dev Biol
Title: Mediator Med23 Regulates Adult Hippocampal Neurogenesis.
Volume: 8
Pages: 699
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Strain
MGI:4839731 | C57BL/6-Tg(Nes-cre/ERT2)1Imayo
Attribute String: transgenic, mutant strain, coisogenic
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Strain
MGI:6146522 | C57BL/6-Tg(Nes-cre/ERT2)1Imayo/Imayo
Attribute String: mutant strain, coisogenic, transgenic
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Genotype
Genotype
Symbol: Rnf2/Rnf2 Tg(Nes-cre/ERT2)5-1Imayo/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ezh2/Ezh2 Tg(Nes-cre/ERT2)5-1Imayo/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Insc/Insc Tg(Nes-cre)1Wmz/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(Nes-cre)1Wmz/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Nes-cre/ERT2)1Imayo/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Nes-cre/ERT2)4Imayo/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Nes-cre/ERT2)4Imayo/?
Background: C57BL/6-Tg(Nes-cre/ERT2)4Imayo
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Nes-cre/ERT2)1Imayo/?
Background: C57BL/6-Tg(Nes-cre/ERT2)1Imayo
Zygosity: ot
Has Mutant Allele: true
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Publication
16014383 | J:100856
First Author: Della Fazia MA
Year: 2005
Journal: J Cell Sci
Title: HOPS: a novel cAMP-dependent shuttling protein involved in protein synthesis regulation.
Volume: 118
Issue: Pt 14
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