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Search results 2601 to 2700 out of 2837 for Prox1

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:3663373
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7713282
Age: embryonic day 14.5
Note: Expression overlapping with Prox1 reporter expression in lymphatic endothelial cells.
Specimen Label: 3C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3663373
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7713282
Age: embryonic day 14.5
Note: Expression overlapping with Prox1 reporter expression in lymphatic endothelial cells.
Specimen Label: 3C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7713255
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7713283
Age: embryonic day 12.5
Note: Co-expression with Prox1 reporter in budding lymphatic endothelial cells.
Specimen Label: 2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7713255
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7713283
Age: embryonic day 12.5
Note: Co-expression with Prox1 reporter in budding lymphatic endothelial cells.
Specimen Label: 2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7713255
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7713283
Age: embryonic day 14.5
Note: Co-expression with Prox1 reporter in budding lymphatic endothelial cells.
Specimen Label: 3A
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7713255
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7713283
Age: embryonic day 14.5
Note: Co-expression with Prox1 reporter in budding lymphatic endothelial cells.
Specimen Label: 3A
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6437765
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7713284
Age: embryonic day 14.5
Note: Expression overlapping with Prox1 reporter expression in lymphatic endothelial cells
Specimen Label: 3D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6437765
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7713284
Age: embryonic day 14.5
Note: Expression overlapping with Prox1 reporter expression in lymphatic endothelial cells
Specimen Label: 3D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5660391
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3553328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5660554
Age: postnatal day 21
Image: 1J
Note: Expressed in the pulmonary lymphatics. Coexpressed with Prox1 and Nfatc1.
Specimen Label: 1J
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:5634415
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3553325
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6758952
Age: embryonic day 17.5
Image: S3A/B/C
Note: Colocalized with Isl1+ lineage and Prox1 around the outflow tract.
Specimen Label: S3A/B/C
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
Probe: MGI:6196894
Assay Type: Immunohistochemistry
Annotation Date: 2018-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6197047
Age: embryonic day 14.5
Image: 2H +/+
Note: Expression overlapped with Prox1 in proliferative lymphatic endothelial cells.
Specimen Label: 2H +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6196894
Assay Type: Immunohistochemistry
Annotation Date: 2018-09-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6197047
Age: embryonic day 14.5
Image: 2H +/LacZ
Note: Expression overlapped with Prox1 in proliferative lymphatic endothelial cells.
Specimen Label: 2H +/LacZ
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5660390
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1635419
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5660396
Age: embryonic day 11.5
Image: 2A
Note: Expressed in endothelial cells. Coexpressed with Prox1 and Flt4.
Specimen Label: 2A
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:5660391
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1635419
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5660554
Age: embryonic day 11.5
Image: 2A
Note: Expressed in endothelial cells. Coexpressed with Prox1 and Nfatc1.
Specimen Label: 2A
Detected: true
Specimen Num: 6
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Allele
Prox1<em1(cre/ERT2)Smoc> | MGI:6758048
Name: prospero homeobox 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
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GXD Expression
GXD Expression
Probe: MGI:4943862
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6758981
Age: embryonic day 10.5
Image: 5C/D
Note: Flt4+/Pecam1+ cells with and without Prox1 expression appeared to form mesh-like network structures, which extended caudally.
Specimen Label: 5C/D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1328239
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6758967
Age: embryonic day 10.5
Image: 5C/D
Note: Flt4+/Pecam1+ cells with and without Prox1 expression appeared to form mesh-like network structures, which extended caudally.
Specimen Label: 5C/D
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
 
Probe: MGI:6314682
Assay Type: Immunohistochemistry
Annotation Date: 2019-06-21
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3553223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6314706
Age: embryonic day 15.75
Note: Authors report weak expression in lymphatic vessel with strong Prox1 expression.
Specimen Label: 3C +/ICD LYVE-1
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:5660390
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Uniform
Stage: TS20
Assay Id: MGI:5660396
Age: embryonic day 12.5
Image: 1E
Note: Expressed in jugular lymph sacs endothelial cells. Expressed in nuclei. Coexpressed with Prox1 and Pdpn.
Specimen Label: 1E
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5660390
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5660396
Age: embryonic day 14.5
Image: 1G
Note: Expressed in the trunk lymphatics. Expressed in nuclei. Coexpressed with Prox1 and Flt4.
Specimen Label: 1G
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:5660390
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5660396
Age: embryonic day 14.5
Image: 1H
Note: Expressed in the lung lymphatics. Expressed in nuclei. Coexpressed with Prox1 and Flt4.
Specimen Label: 1H
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:5660390
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5660396
Age: embryonic day 14.5
Image: 1I
Note: Expressed in the dermal lymphatics. Expressed in nuclei. Coexpressed with Prox1 and Flt4.
Specimen Label: 1I
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:5660390
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5660396
Age: embryonic day 11.5
Image: 2A
Note: Expressed in lymphatic endothelial cells sprouting from the cardinal vein. Coexpressed with Prox1 and Flt4.
Specimen Label: 2A
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:5660391
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Uniform
Stage: TS20
Assay Id: MGI:5660554
Age: embryonic day 12.5
Image: 1D
Note: Uniform bilateral expression in jugular lymph sacs endothelial cells. Coexpressed with Prox1 and Nfatc1.
Specimen Label: 1D
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5660391
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5660554
Age: embryonic day 11.5
Image: 2A
Note: Expressed in lymphatic endothelial cells sprouting from the cardinal vein. Coexpressed with Prox1 and Nfatc1.
Specimen Label: 2A
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:5476703
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5660608
Age: embryonic day 12.5
Image: 1E
Note: Expressed in jugular lymph sacs endothelial cells. Coexpressed with Prox1 and Nfatc1.
Specimen Label: 1E
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5634415
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6758952
Age: embryonic day 12.0
Image: 6A
Note: Expressed in vessels around the sinus venosus. No coexpression with Prox1 mostly.
Specimen Label: 6A
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
Probe: MGI:5660390
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3553328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5660396
Age: postnatal day 21
Image: 1J
Note: Expressed in the pulmonary lymphatics. Expressed in nuclei. Coexpressed with Prox1 and Flt4.
Specimen Label: 1J
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:4943862
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1627217
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6758981
Age: embryonic day 10.5
Image: 5C/D
Note: Flt4+/Pecam1+ cells with and without Prox1 expression appeared to form mesh-like network structures, which extended caudally.
Specimen Label: 5C/D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1328239
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1627217
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6758967
Age: embryonic day 10.5
Image: 5C/D
Note: Flt4+/Pecam1+ cells with and without Prox1 expression appeared to form mesh-like network structures, which extended caudally.
Specimen Label: 5C/D
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
Probe: MGI:6454053
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6454343
Age: embryonic day 13.5
Image: 1C
Note: Lymphatic endothelial cells in the jugular lymph sacs co-express Prox1 and Lyve1.
Specimen Label: 1C
Detected: true
Specimen Num: 1
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Protein Coding Gene
MGI:109258 | Nprl3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
16470382 | J:164796
First Author: Nishijima I
Year: 2006
Journal: Mol Genet Genomics
Title: Characterization of a novel prospero-related homeobox gene, Prox2.
Volume: 275
Issue: 5
Pages: 471-8
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GXD Expression
GXD Expression
Probe: MGI:7645507
Assay Type: Immunohistochemistry
Annotation Date: 2024-06-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3524723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7645521
Age: embryonic day 15.0
Image: 5B
Note: Co expression with Prox1 in subset of cells within zone of proliferating cells (ZNP"C) at basal end.
Specimen Label: 5B
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:5634415
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3664123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7614745
Age: embryonic day 15.5
Image: 1-S1 E15.5 PROX1/LYVE-1/Endomucin
Note: Coexpressed with Prox1 in the lymphatic plexus. Weak expression of the blood endothelial marker endomucin relative to surrounding blood vasculature.
Specimen Label: 1-S1 E15.5 PROX1/LYVE-1/Endomucin
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5634415
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3664123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7614745
Age: embryonic day 15.5
Image: 1-S1 E15.5 PROX1/LYVE-1/Endomucin
Note: Coexpressed with Prox1 in the lymphatic plexus. Weak expression of the blood endothelial marker endomucin relative to surrounding blood vasculature.
Specimen Label: 1-S1 E15.5 PROX1/LYVE-1/Endomucin
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5660390
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Uniform
Stage: TS20
Assay Id: MGI:5660396
Age: embryonic day 12.5
Image: 1B/D
Note: Uniform bilateral expression in jugular lymph sacs endothelial cells. Expressed in nuclei. Coexpressed with Prox1 and Flt4.
Specimen Label: 1B/D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5660390
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Uniform
Stage: TS20
Assay Id: MGI:5660396
Age: embryonic day 12.5
Image: S1A/C
Note: Uniform bilateral expression in developing jugular lymph sacs endothelial cells and sprouting lymphatic endothelial cells. Coexpressed with Prox1 and Flt4.
Specimen Label: S1A/C
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
Probe: MGI:5660390
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5660396
Age: embryonic day 12.5
Image: S1D
Note: Uniform bilateral expression in developing jugular lymph sacs endothelial cells and sprouting lymphatic endothelial cells. Coexpressed with Prox1 and Pdpn.
Specimen Label: S1D
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
Probe: MGI:5660391
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Uniform
Stage: TS20
Assay Id: MGI:5660554
Age: embryonic day 12.5
Image: S1C
Note: Uniform bilateral expression in developing jugular lymph sacs endothelial cells and sprouting lymphatic endothelial cells. Coexpressed with Prox1 and Nfatc1.
Specimen Label: S1C
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:5476703
Assay Type: Immunohistochemistry
Annotation Date: 2015-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1824820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5660608
Age: embryonic day 12.5
Image: S1D
Note: Uniform bilateral expression in developing jugular lymph sacs endothelial cells and sprouting lymphatic endothelial cells. Coexpressed with Prox1 and Nfatc1.
Specimen Label: S1D
Detected: true
Specimen Num: 2
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Strain
MGI:6429429 | C57BL/6JSmoc-Prox1<em1(cre/ERT2)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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GXD Expression
GXD Expression
Probe: MGI:7614743
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3664126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7614751
Age: embryonic day 18.5
Image: 1-S2D
Note: Coexpressed with Prox1 in the lymphatic vessels. No lymphatic vessels in the renal medulla region (Aqp2+), nor near or within the renal capsule.
Specimen Label: 1-S2D
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7614743
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3664126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7614751
Age: embryonic day 18.5
Image: 1-S2D
Note: Coexpressed with Prox1 in the lymphatic vessels. No lymphatic vessels in the renal medulla region (Aqp2+), nor near or within the renal capsule.
Specimen Label: 1-S2D
Detected: true
Specimen Num: 4
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Publication
20962325 | J:168413
First Author: Choi I
Year: 2011
Journal: Blood
Title: Visualization of lymphatic vessels by Prox1-promoter directed GFP reporter in a bacterial artificial chromosome-based transgenic mouse.
Volume: 117
Issue: 1
Pages: 362-5
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Publication
35589749 | J:325616
First Author: Meçe O
Year: 2022
Journal: Nat Commun
Title: Lipid droplet degradation by autophagy connects mitochondria metabolism to Prox1-driven expression of lymphatic genes and lymphangiogenesis.
Volume: 13
Issue: 1
Pages: 2760
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Publication
12529405 | -
First Author: Bi X
Year: 2003
Journal: Mol Cell Biol
Title: The carboxy terminus of Prospero regulates its subcellular localization.
Volume: 23
Issue: 3
Pages: 1014-24
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Publication
1673362 | -
First Author: Doe CQ
Year: 1991
Journal: Cell
Title: The prospero gene specifies cell fates in the Drosophila central nervous system.
Volume: 65
Issue: 3
Pages: 451-64
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Publication
27068465 | -
First Author: Wallace SW
Year: 2016
Journal: Cell Rep
Title: PROS-1/Prospero Is a Major Regulator of the Glia-Specific Secretome Controlling Sensory-Neuron Shape and Function in C. elegans.
Volume: 15
Issue: 3
Pages: 550-562
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Publication
15205472 | -
First Author: Qin J
Year: 2004
Journal: Mol Endocrinol
Title: Prospero-related homeobox (Prox1) is a corepressor of human liver receptor homolog-1 and suppresses the transcription of the cholesterol 7-alpha-hydroxylase gene.
Volume: 18
Issue: 10
Pages: 2424-39
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Publication
19035352 | -
First Author: Pistocchi A
Year: 2008
Journal: Dev Dyn
Title: Identification and expression pattern of zebrafish prox2 during embryonic development.
Volume: 237
Issue: 12
Pages: 3916-20
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Protein Domain
IPR039350 | Prospero_homeodomain
Type: Family
Description: Prospero-related proteins are conserved among metazoa and play important roles in development. They contain two characteristic conserved domains termed prospero domain 1 (PD1) and PD2 []. Drosophila Pros plays well-known roles in the establishment of cell fate during nervous system development []. In C. elegans, Prox1 functions as a major regulator of the glia-specific secretome that controls shape and function of sensory neurons []. Vertebrate Prox1 plays divergent roles in multiple organs by associating with nuclear receptors and modulating their transcriptional activities [, , ]. A second member of the family, Prox2, is present in vertebrates [, ].
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Allele
Rhbdf1/Hba<tm2Ajhs> | MGI:5309140
 
Name: hemoglobin alpha chain complex; targeted mutation 2, Andrew JH Smith
Allele Type: Targeted
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Allele
Rhbdf1/Hba<tm2Ajhs> | MGI:5309141
 
Name: rhomboid 5 homolog 1; targeted mutation 2, Andrew JH Smith
Allele Type: Targeted
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GXD Expression
GXD Expression
Probe: MGI:5660390
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1635417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:5660396
Age: embryonic day 10.5
Image: 1A
Note: Expressed in the cardinal vein endothelial cells and lymphatic endothelial cells sprouting from the cardinal vein. Expressed in nuclei, as shown in inset. Nfatc1 and Prox1 were colocalized only in the regions of active lymphatic sprouting.
Specimen Label: 1A
Detected: true
Specimen Num: 1
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Publication
39196043 | J:358597
First Author: Hong SP
Year: 2023
Journal: Nat Cardiovasc Res
Title: Three-dimensional morphologic and molecular atlases of nasal vasculature.
Volume: 2
Issue: 5
Pages: 449-466
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Allele
Tg(Prox1-EGFP)KY221Gsat | MGI:4847348
Name: transgene insertion KY221, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Prox1-tdTomato)TA76Gsat | MGI:5311713
Name: transgene insertion TA76, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Tg(Prox1-cre)SJ32Gsat | MGI:5435513
Name: transgene insertion SJ32, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Prox1-cre)SJ39Gsat | MGI:5435522
Name: transgene insertion SJ39, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Prox1-cre/ERT2)1Tmak | MGI:5617984
Name: transgene insertion 1, Taija Makinen
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Allele
Tg(Prox1-Lgi1)#Ran | MGI:7466678
Name: transgene insertion, Roger A Nicoll
Allele Type: Transgenic
Attribute String: Epitope tag, Inserted expressed sequence
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Allele
Tg(Prox1-cre/ERT2)1Jscal | MGI:7537333
Name: transgene insertion 1, Joshua Scallan
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Genotype
Genotype
Symbol: Rhbdf1/Hba/Hba<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rhbdf1/Hba/Rhbdf1<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rhbdf1/Hba/Rhbdf1/Hba
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rhbdf1/Hba/Rhbdf1/Hba
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
28814666 | J:283249
 
First Author: Baluk P
Year: 2017
Journal: JCI Insight
Title: Rapamycin reversal of VEGF-C-driven lymphatic anomalies in the respiratory tract.
Volume: 2
Issue: 16
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Publication
38367239 | J:350583
First Author: Gu X
Year: 2024
Journal: Cell Rep
Title: Macrophage-induced integrin signaling promotes Schlemm's canal formation to prevent intraocular hypertension and glaucomatous optic neuropathy.
Volume: 43
Issue: 2
Pages: 113799
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Publication
25849579 | J:233411
First Author: Bianchi R
Year: 2015
Journal: PLoS One
Title: A transgenic Prox1-Cre-tdTomato reporter mouse for lymphatic vessel research.
Volume: 10
Issue: 4
Pages: e0122976
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Allele
Prox1<tm5(GFP/cre)Gco> | MGI:4441289
Name: prospero homeobox 1; targeted mutation 5, Guillermo Oliver
Allele Type: Targeted
Attribute String: Recombinase, Reporter
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Strain
MGI:5004059 | STOCK Tg(Prox1-EGFP)KY221Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Publication
39731913 | J:361230
     
First Author: Lei PJ
Year: 2024
Journal: Dev Cell
Title: Aging-induced changes in lymphatic muscle cell transcriptomes are associated with reduced pumping of peripheral collecting lymphatic vessels in mice.
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Publication
32766737 | J:359094
 
First Author: Pujari A
Year: 2020
Journal: J Biomech Eng
Title: Lymphatic Valves Separate Lymph Flow Into a Central Stream and a Slow-Moving Peri-Valvular Milieu.
Volume: 142
Issue: 10
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Publication
39422453 | J:359058
   
First Author: Balasubramanian R
Year: 2024
Journal: Elife
Title: Transcriptomic profiling of Schlemm's canal cells reveals a lymphatic-biased identity and three major cell states.
Volume: 13
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Publication
38200313 | J:349942
First Author: Yoon JH
Year: 2024
Journal: Nature
Title: Nasopharyngeal lymphatic plexus is a hub for cerebrospinal fluid drainage.
Volume: 625
Issue: 7996
Pages: 768-777
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Publication
32417103 | J:349662
First Author: Yang Y
Year: 2020
Journal: Ocul Surf
Title: High resolution three-dimensional imaging of the ocular surface and intact eyeball using tissue clearing and light sheet microscopy.
Volume: 18
Issue: 3
Pages: 526-532
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Publication
32173554 | J:349661
First Author: Shi M
Year: 2020
Journal: Ocul Surf
Title: Aqueous humor induces lymphatic regression on the ocular surface.
Volume: 18
Issue: 3
Pages: 505-510
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Publication
26785921 | J:286572
 
First Author: Kang GJ
Year: 2016
Journal: Sci Rep
Title: Intravital Imaging Reveals Dynamics of Lymphangiogenesis and Valvulogenesis.
Volume: 6
Pages: 19459
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Publication
24013505 | J:201151
First Author: Rodríguez-Seguel E
Year: 2013
Journal: Genes Dev
Title: Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence.
Volume: 27
Issue: 17
Pages: 1932-46
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Publication
23285114 | J:195757
First Author: Svingen T
Year: 2012
Journal: PLoS One
Title: Three-dimensional imaging of Prox1-EGFP transgenic mouse gonads reveals divergent modes of lymphangiogenesis in the testis and ovary.
Volume: 7
Issue: 12
Pages: e52620
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Publication
24248345 | J:264941
First Author: Grindberg RV
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: RNA-sequencing from single nuclei.
Volume: 110
Issue: 49
Pages: 19802-7
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Publication
31616011 | J:284209
First Author: Ma Q
Year: 2019
Journal: Sci Rep
Title: Lymphatic outflow of cerebrospinal fluid is reduced in glioma.
Volume: 9
Issue: 1
Pages: 14815
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Publication
37244593 | J:350962
 
First Author: Yang Y
Year: 2023
Journal: Ocul Surf
Title: Novel discovery of a lymphatic bridge connecting Schlemm's canal to limbal and conjunctival lymphatic pathway.
Volume: 29
Pages: 272-278
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Publication
27090946 | J:361313
 
First Author: Lacar B
Year: 2016
Journal: Nat Commun
Title: Nuclear RNA-seq of single neurons reveals molecular signatures of activation.
Volume: 7
Pages: 11022
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Strain
MGI:5312982 | STOCK Tg(Prox1-tdTomato)TA76Gsat/Mmucd
Attribute String: transgenic, mutant stock
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Allele
Tg(Prox1-tdTomato)12Nrud | MGI:5316745
Name: transgene insertion 12, Nancy H Ruddle
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:5316749 | B6;129S-Tg(Prox1-tdTomato)12Nrud/J
Attribute String: mutant stock, transgenic
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Strain
MGI:5488978 | STOCK Tg(Prox1-tdTomato)12Nrud/J
Attribute String: transgenic, mutant stock
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Strain
MGI:5435834 | STOCK Tg(Prox1-cre)SJ32Gsat/Mmucd
Attribute String: transgenic, mutant stock
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Strain
MGI:5435843 | STOCK Tg(Prox1-cre)SJ39Gsat/Mmucd
Attribute String: transgenic, mutant stock
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Strain
MGI:6438646 | B6.Cg-Tg(Prox1-cre/ERT2)1Tmak/Tac
Attribute String: mutant strain, congenic, transgenic
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Strain
MGI:7570905 | C57BL/6-Tg(Prox1-cre/ERT2)1Tmak/H
Attribute String: congenic, mutant strain, transgenic
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Publication
27810998 | J:262645
First Author: Bianchi R
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Postnatal Deletion of Podoplanin in Lymphatic Endothelium Results in Blood Filling of the Lymphatic System and Impairs Dendritic Cell Migration to Lymph Nodes.
Volume: 37
Issue: 1
Pages: 108-117
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Allele
Tg(Prox1-cre)#Fkfr | MGI:7437467
Name: transgene insertion, Friedemann Kiefer
Allele Type: Transgenic
Attribute String: Recombinase
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Genotype
Genotype
Symbol: Prox1/Prox1<+>
Background: involves: 129S1/Sv * NMRI
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prox1-EGFP)KY221Gsat/?
Background: involves: FVB/NTac
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prox1/Prox1<+>
Background: involves: 129S1/Sv
Zygosity: ht
Has Mutant Allele: true
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Publication
38718095 | J:351084
First Author: K C R
Year: 2024
Journal: PLoS One
Title: Zmiz1 is a novel regulator of lymphatic endothelial cell gene expression and function.
Volume: 19
Issue: 5
Pages: e0302926
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Publication
28930285 | J:309766
First Author: Park HJ
Year: 2018
Journal: Mucosal Immunol
Title: Interleukin-17A negatively regulates lymphangiogenesis in T helper 17 cell-mediated inflammation.
Volume: 11
Issue: 3
Pages: 590-600
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