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Search results 2601 to 2700 out of 3068 for Ret

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Hits by Pathway

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Hits by Strain

Type Details Score
Genotype
Genotype
Symbol: Nkx6-2/Nkx6-2<+> Ret/Ret
Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ret/Ret Tg(CAG-cre/Esr1*)5Amc/?
Background: involves: 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ret/Ret Tg(CD2-icre)4Kio/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/10 * CBA/Ca
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kifbp/Kifbp Ret/Ret<+>
Background: involves: 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Phactr4/Phactr4 Ret/Ret<+>
Background: involves: 129X1/SvJ * C3H/HeN * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Publication
9778055 | J:50392
First Author: Kato M
Year: 1998
Journal: Oncogene
Title: Transgenic mouse model for skin malignant melanoma.
Volume: 17
Issue: 14
Pages: 1885-8
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Publication
8439501 | J:343471
First Author: Iwamoto T
Year: 1993
Journal: Br J Cancer
Title: Neuroblastoma in a transgenic mouse carrying a metallothionein/ret fusion gene.
Volume: 67
Issue: 3
Pages: 504-7
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Protein Coding Gene
MGI:103232 | Grb10
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:106179 | Shc3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q60760
Organism: Mus musculus/domesticus
Length: 621  
Fragment?: false
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Protein
Q61120
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
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Publication
28405502 | J:302466
First Author: Bod L
Year: 2017
Journal: Oncoimmunology
Title: IL4-induced gene 1 promotes tumor growth by shaping the immune microenvironment in melanoma.
Volume: 6
Issue: 3
Pages: e1278331
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Publication
29089297 | J:253858
First Author: Blattner C
Year: 2018
Journal: Cancer Res
Title: CCR5+ Myeloid-Derived Suppressor Cells Are Enriched and Activated in Melanoma Lesions.
Volume: 78
Issue: 1
Pages: 157-167
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Publication
14973052 | J:88453
First Author: Lengagne R
Year: 2004
Journal: Cancer Res
Title: Spontaneous vitiligo in an animal model for human melanoma: role of tumor-specific CD8+ T cells.
Volume: 64
Issue: 4
Pages: 1496-501
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Publication
1868872 | J:276582
First Author: Iwamoto T
Year: 1991
Journal: Eur J Immunol
Title: Preferential development of pre-B lymphomas with drastically down-regulated N-myc in the E mu-ret transgenic mice.
Volume: 21
Issue: 8
Pages: 1809-14
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Publication
7710948 | J:343498
First Author: Ichihara M
Year: 1995
Journal: Br J Cancer
Title: Oncogene-linked in situ immunotherapy of pre-B lymphoma arising in E mu/ret transgenic mice.
Volume: 71
Issue: 4
Pages: 808-13
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Protein Domain
IPR041317 | RET_CLD4
Type: Domain
Description: RET is a single transmembrane-spanning receptor tyrosine kinase (RTK) that plays critical roles in the development of vertebrates. Structural analysis indicate that the ligand-binding RET ectodomain (RET-ECD) contains four consecutive cadherin-like domains (CLD1-CLD4) followed by a membrane-proximal cysteine-rich domain (CRD). This entry relates to CLD4 which is required for CRD folding [].
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Protein Domain
IPR040667 | Ret_CLD3
Type: Domain
Description: RET is a single transmembrane-spanning receptor tyrosine kinase (RTK) that plays critical roles in the development of vertebrates. Structural analysis indicate that RET contains four consecutive cadherin-like domains (CLD). This entry relates to CLD3. Classical cadherin calcium-coordinating motifs can be found between CLD2 and CLD3 [].
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HT Experiment
GSE77891 | RNA-SEQ analysis of E18.5 ALL Ret-positive (EGFP-labeled) male or female dorsal root ganglia neurons.
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE77892 | RNA-SEQ analysis of E14.5 ALL Ret-positive (EGFP-labeled) FACSd dorsal root ganglia neurons.
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE98592 | RNA-SEQ analysis of E12.5 ALL Ret-positive (EGFP-labeled) FACSd dorsal root ganglia neurons
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
9808544 | J:50955
First Author: Zeng XX
Year: 1998
Journal: Blood
Title: The fetal origin of B-precursor leukemia in the E-mu-ret mouse.
Volume: 92
Issue: 10
Pages: 3529-36
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Genotype
Genotype
Symbol: Ret/Ret<+> Wnt11/Wnt11
Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * MF1
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lhx1/Lhx1<+> Ret/Ret Tg(Nes-cre)1Kln/?
Background: involves: 129/Sv * BALB/c * C57BL/6 * CBA/J * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lhx1/Lhx1<+> Ret/Ret
Background: involves: 129/Sv * BALB/c * C57BL/6 * CBA/J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gfra1/Gfra1 Ret/Ret<+>
Background: involves: 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ret/Ret H2az2/H2az2<+>
Background: involves: 129 * C57BL/6 * C57BL/6J * CBA/J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Islr2/Islr2 Ret/Ret<+>
Background: involves: 129S6/SvEvTac * BALB/cJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax2/Pax2<+> Ret/Ret<+>
Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dhcr7/Dhcr7 Ret/Ret<+> Tg(Pgk1-cre)1Lni/?
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mrgprd/Mrgprd<+> Ret/Ret
Background: involves: 129 * 129S1/Sv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kifbp/Kifbp<+> Ret/Ret
Background: involves: 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
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Publication
17159911 | J:121091
First Author: Kato M
Year: 2007
Journal: J Invest Dermatol
Title: Protective effect of hyperpigmented skin on UV-mediated cutaneous cancer development.
Volume: 127
Issue: 5
Pages: 1244-9
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Allele
Tg(Hoxb7-RET/AKAP1)1Cos | MGI:2388558
Name: transgene insertion 1, Frank Costantini
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Hoxb7-RET-C634K)1Vpa | MGI:2388559
Name: transgene insertion 1, Vassilis Pachnis
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Hoxb7-RET-M918T)1Vpa | MGI:2388560
Name: transgene insertion 1, Vassilis Pachnis
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Hoxb7-RET-C634K)2Vpa | MGI:2388561
Name: transgene insertion 2, Vassilis Pachnis
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Hoxb7-RET-M918T)2Vpa | MGI:2388562
Name: transgene insertion 2, Vassilis Pachnis
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Mt1-RET)304Ina | MGI:3039777
Name: transgene insertion 304, Izumi Nakashima
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Mt1-RET)242Ina | MGI:3053982
Name: transgene insertion 242, Izumi Nakashima
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(TG-RET/CCDC6)42Cled | MGI:5569727
Name: transgene insertion 42, Catherine Ledent
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(TG-RET/NCOA4)3209Rstn | MGI:5569734
Name: transgene insertion 3209, Jay Rothstein
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(TG-RET/CCDC6)1Cled | MGI:5569664
Name: transgene insertion 1, Catherine Ledent
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Gt(ROSA)26Sor<tm4(Ret,tdTomato)Cos> | MGI:6501781
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 4, Franklin Costantini
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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HT Experiment
E-GEOD-32093 | Expression data from E12.5 embryonic kidneys isolated from wild-type and Ret-deficient mice
Series Id: GSE32093
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
20048069 | J:155735
First Author: Kumasaka MY
Year: 2010
Journal: Cancer Res
Title: A novel mouse model for de novo Melanoma.
Volume: 70
Issue: 1
Pages: 24-9
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Publication
15743795 | J:96719
First Author: von Felbert V
Year: 2005
Journal: Am J Pathol
Title: Interleukin-6 gene ablation in a transgenic mouse model of malignant skin melanoma.
Volume: 166
Issue: 3
Pages: 831-41
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Protein Coding Gene
MGI:102683 | Grb7
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q03160
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: false
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Publication
19275641 | -
First Author: Sharma PS
Year: 2009
Journal: Curr Pharm Des
Title: Receptor tyrosine kinase inhibitors as potent weapons in war against cancers.
Volume: 15
Issue: 7
Pages: 758-76
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Publication
16700535 | -
First Author: Li E
Year: 2006
Journal: Biochemistry
Title: Role of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies.
Volume: 45
Issue: 20
Pages: 6241-51
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Publication
15845350 | -
First Author: Roskoski R Jr
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Src kinase regulation by phosphorylation and dephosphorylation.
Volume: 331
Issue: 1
Pages: 1-14
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Genotype
Genotype
Symbol: Ret/Ret<+> Wnt11/Wnt11<+>
Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * MF1
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mrgprd/? Ret/Ret H2az2/H2az2<+>
Background: involves: 129 * 129S1/Sv * C57BL/6 * C57BL/6J * CBA/J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bax/Bax Ret/Ret Tg(CAG-cre/Esr1*)5Amc/?
Background: involves: 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ret/Ret Slc6a3/Slc6a3<+>
Background: involves: 129S1/Sv
Zygosity: cn
Has Mutant Allele: true
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Publication
18097012 | J:130879
First Author: Lengagne R
Year: 2008
Journal: J Immunol
Title: Distinct role for CD8 T cells toward cutaneous tumors and visceral metastases.
Volume: 180
Issue: 1
Pages: 130-7
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Publication
23878221 | J:200705
First Author: Pommier A
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Inflammatory monocytes are potent antitumor effectors controlled by regulatory CD4+ T cells.
Volume: 110
Issue: 32
Pages: 13085-90
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Publication
1915289 | J:70622
First Author: Iwamoto T
Year: 1991
Journal: EMBO J
Title: Aberrant melanogenesis and melanocytic tumour development in transgenic mice that carry a metallothionein/ret fusion gene.
Volume: 10
Issue: 11
Pages: 3167-75
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Strain
MGI:4418533 | B6.C-Tg(Mt1-RET)304Ina
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:3763407 | B6.Cg-Tg(Mt1-RET)304Ina/NumRbrc
Attribute String: transgenic, mutant strain
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Strain
MGI:3053961 | B6;C-Tg(Mt1-RET)304Ina
Attribute String: mutant stock, transgenic
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Publication
9764846 | J:52701
First Author: Kato M
Year: 1998
Journal: J Invest Dermatol
Title: The herbal medicine Sho-saiko-to inhibits growth and metastasis of malignant melanoma primarily developed in ret-transgenic mice.
Volume: 111
Issue: 4
Pages: 640-4
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Publication
25977583 | J:222931
First Author: Bauer AT
Year: 2015
Journal: Blood
Title: von Willebrand factor fibers promote cancer-associated platelet aggregation in malignant melanoma of mice and humans.
Volume: 125
Issue: 20
Pages: 3153-63
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Publication
10777360 | J:61987
First Author: Kato M
Year: 2000
Journal: J Invest Dermatol
Title: Further characterization of the Sho-saio-to-mediated anti-tumor effect on melanoma developed in RET-transgenic mice.
Volume: 114
Issue: 3
Pages: 599-601
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Publication
20194633 | J:158124
First Author: Helfrich I
Year: 2010
Journal: J Exp Med
Title: Resistance to antiangiogenic therapy is directed by vascular phenotype, vessel stabilization, and maturation in malignant melanoma.
Volume: 207
Issue: 3
Pages: 491-503
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Strain
MGI:6146715 | ICR.Cg-Tg(Mt1-RET)242Ina/Rbrc
Attribute String: mutant strain, congenic, transgenic
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Strain
MGI:3054011 | B6;C-Tg(Mt1-RET)242Ina
Attribute String: mutant stock, transgenic
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Strain
MGI:3763405 | B6.Cg-Tg(Mt1-RET)242Ina/NumRbrc
Attribute String: mutant strain, transgenic
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Publication
15350277 | J:92389
First Author: Hayashi H
Year: 2004
Journal: Hear Res
Title: A novel RFP-RET transgenic mouse model with abundant eumelanin in the cochlea.
Volume: 195
Issue: 1-2
Pages: 35-40
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Allele
Tg(Mt1-RET)192Ina | MGI:3054014
Name: transgene insertion 192, Izumi Nakashima
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(CALCA-RET*C634R)1Bajp | MGI:3525083
Name: transgene insertion 1, Bruce AJ Ponder
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(CALCA-RET*C634R)2Bajp | MGI:3525090
Name: transgene insertion 2, Bruce AJ Ponder
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(DBH-RET*M918T)CH7720Rpk | MGI:3767822
Name: transgene insertion CH7720, Raj P Kapur
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(DBH-RET*M918T)CH7194Rpk | MGI:3767823
Name: transgene insertion CH7194, Raj P Kapur
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(DBH-RET*M918T)CH7214Rpk | MGI:3767825
Name: transgene insertion CH7214, Raj P Kapur
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Hoxb7-Ret)LCos | MGI:5426785
Name: transgene insertion L, Frank Costantini
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
9850089 | J:51366
First Author: Powell DJ Jr
Year: 1998
Journal: Cancer Res
Title: The RET/PTC3 oncogene: metastatic solid-type papillary carcinomas in murine thyroids.
Volume: 58
Issue: 23
Pages: 5523-8
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Publication
9121114 | J:209792
First Author: Sagartz JE
Year: 1997
Journal: Lab Invest
Title: Thyroid-stimulating hormone promotes growth of thyroid carcinomas in transgenic mice with targeted expression of the ret/PTC1 oncogene.
Volume: 76
Issue: 3
Pages: 307-18
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Strain
MGI:6501782 | B6;129-Gt(ROSA)26Sor<tm4(Ret,tdTomato)Cos>/J
Attribute String: targeted mutation, mutant stock
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Allele
Gt(ROSA)26Sor<tm5(RET*,tdTomato)Cos> | MGI:6501783
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 5, Franklin Costantini
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter
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Allele
Gt(ROSA)26Sor<tm6(RET*,tdTomato)Cos> | MGI:6501786
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 6, Franklin Costantini
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter
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Strain
MGI:6501790 | B6;129-Gt(ROSA)26Sor<tm6(Ret*,tdTomato)Cos>/J
Attribute String: targeted mutation, mutant stock
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Allele
Tg(Emu-RET)385Ina | MGI:7398501
Name: transgene insertion 385, Izumi Nakashima
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
14657335 | J:86983
First Author: Brown VI
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Rapamycin is active against B-precursor leukemia in vitro and in vivo, an effect that is modulated by IL-7-mediated signaling.
Volume: 100
Issue: 25
Pages: 15113-8
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Publication
9639527 | J:48500
First Author: Wasserman R
Year: 1998
Journal: Blood
Title: The evolution of B precursor leukemia in the Emu-ret mouse.
Volume: 92
Issue: 1
Pages: 273-82
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Publication
37824841 | J:343271
First Author: Atre T
Year: 2023
Journal: Blood Adv
Title: Age and ligand specificity influence the outcome of pathogen engagement on preleukemic and leukemic B-cell precursor populations.
Volume: 7
Issue: 22
Pages: 7087-7099
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Publication
38519798 | J:352282
First Author: Farrokhi A
Year: 2024
Journal: Leukemia
Title: The Eμ-Ret mouse is a novel model of hyperdiploid B-cell acute lymphoblastic leukemia.
Volume: 38
Issue: 5
Pages: 969-980
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Genotype
Genotype
Symbol: Tg(Mt1-RET)304Ina/?
Background: B6.C-Tg(Mt1-RET)304Ina
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Mt1-RET)304Ina/?
Background: involves: BALB/c * C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(TG-RET/CCDC6)1Cled/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(TG-RET/CCDC6)42Cled/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(TG-RET/NCOA4)3209Rstn/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Publication
11779046 | J:74400
First Author: Rajan I
Year: 2001
Journal: Pediatr Dev Pathol
Title: RET(Men2B)-transgene produces sympathoadrenal tumors but does not prevent intestinal aganglionosis in gdnf-/- or gfr alpha-1(-/-) mice.
Volume: 4
Issue: 5
Pages: 446-53
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Publication
21969559 | J:177454
First Author: Meyer C
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model.
Volume: 108
Issue: 41
Pages: 17111-6
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Publication
10023663 | J:108163
First Author: Sweetser DA
Year: 1999
Journal: Oncogene
Title: Ganglioneuromas and renal anomalies are induced by activated RET(MEN2B) in transgenic mice.
Volume: 18
Issue: 4
Pages: 877-86
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Protein Coding Gene
MGI:1333854 | Gab2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q9Z1S8
Organism: Mus musculus/domesticus
Length: 665  
Fragment?: false
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Publication
12374762 | J:79616
First Author: Akey DT
Year: 2002
Journal: Hum Mol Genet
Title: The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1.
Volume: 11
Issue: 22
Pages: 2723-33
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Publication
17244780 | -
First Author: Daly AF
Year: 2007
Journal: J Clin Endocrinol Metab
Title: Aryl hydrocarbon receptor-interacting protein gene mutations in familial isolated pituitary adenomas: analysis in 73 families.
Volume: 92
Issue: 5
Pages: 1891-6
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