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Search results 2601 to 2700 out of 3183 for Runx1

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Type Details Score
GXD Expression
GXD Expression
Probe: MGI:5619304
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3670213
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:6401469
Age: embryonic day 8.5
Image: 8A
Note: Co-expression with Runx1 in some cells of ventral hindgut (hindgut lip and ventral midline of hindgut); other expressing cells lack Runx1 expression.
Specimen Label: 8A
Detected: true
Specimen Num: 2
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Pathway
R-MMU-8877330 | RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)
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Pathway
R-MMU-8939243 | RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
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Pathway
R-MMU-8939246 | RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
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Publication
12217689 | -
First Author: Bäckström S
Year: 2002
Journal: J Mol Biol
Title: The RUNX1 Runt domain at 1.25A resolution: a structural switch and specifically bound chloride ions modulate DNA binding.
Volume: 322
Issue: 2
Pages: 259-72
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Allele
Runx1<tm4Dow> | MGI:3040872
Name: runt related transcription factor 1; targeted mutation 1, James R Downing
Allele Type: Targeted
Attribute String: Reporter
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Allele
Tg(CD2-Runx1)81Sata | MGI:3771952
Name: transgene insertion 81, Masanobu Satake
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Runx1<em1Smoc> | MGI:7292140
Name: runt related transcription factor 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Publication
36064547 | J:328140
First Author: Asgarian Z
Year: 2022
Journal: Nat Commun
Title: MTG8 interacts with LHX6 to specify cortical interneuron subtype identity.
Volume: 13
Issue: 1
Pages: 5217
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Genotype
Genotype
Symbol: Runx1t1/Runx1t1<+> Runx1/Runx1<+> Tg(Nes-cre)1Atp/?
Background: involves: FVB/N
Zygosity: cn
Has Mutant Allele: true
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Publication
16227606 | J:102172
First Author: Amann JM
Year: 2005
Journal: Mol Cell Biol
Title: Mtgr1 is a transcriptional corepressor that is required for maintenance of the secretory cell lineage in the small intestine.
Volume: 25
Issue: 21
Pages: 9576-85
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Publication
19618476 | J:150704
First Author: Alishahi A
Year: 2009
Journal: Dev Dyn
Title: Regional expression of MTG genes in the developing mouse central nervous system.
Volume: 238
Issue: 8
Pages: 2095-102
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Publication
28640846 | J:246527
First Author: Liao KH
Year: 2017
Journal: PLoS One
Title: Endothelial angiogenesis is directed by RUNX1T1-regulated VEGFA, BMP4 and TGF-β2 expression.
Volume: 12
Issue: 6
Pages: e0179758
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HT Experiment
GSE68958 | RUNX1B expression distinguishes megakaryocytic and erythroid lineage fate in adult hematopoiesis
Series Id: E-GEOD-68958
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE68998 | Runx1- responsive genes in mdx muscles
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Spi1<tm3Dgt> | MGI:3773989
 
Name: Spi-1 proto-oncogene; targeted mutation 3, Daniel G Tenen
Allele Type: Targeted
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Allele
Tg(Runx1-GFP)#Itan | MGI:4458874
Name: transgene insertion, Ichiro Taniuchi
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Gt(ROSA)26Sor<tm1(CAG-Runx1)Lzjg> | MGI:7490340
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Zijing Liu
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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HT Experiment
GSE84136 | Expression Profile of CHD7-Deficient Murine Long-term Hematopoietic Stem Cells
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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Protein Coding Gene
MGI:3042250 | Serpinb13
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:98510 | Tcf3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:107180 | Elf1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:3512628 | Cbx6
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1923505 | Pcgf5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:894762 | Ldb1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:102811 | Lmo2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1916507 | Elf2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:97489 | Pax5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:98480 | Tal1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1919847 | Auts2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:102812 | Lmo1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:101877 | Tcf12
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1891436 | Foxp3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P15806
Organism: Mus musculus/domesticus
Length: 651  
Fragment?: false
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Protein
A0A087WPF7
Organism: Mus musculus/domesticus
Length: 1261  
Fragment?: false
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Protein
Q60775
Organism: Mus musculus/domesticus
Length: 612  
Fragment?: false
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Protein
P25801
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: false
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Protein
Q924W9
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: false
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Protein
P70662
Organism: Mus musculus/domesticus
Length: 411  
Fragment?: false
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Protein
Q02650
Organism: Mus musculus/domesticus
Length: 391  
Fragment?: false
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Protein
Q3UK78
Organism: Mus musculus/domesticus
Length: 256  
Fragment?: false
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Protein
Q9DBY5
Organism: Mus musculus/domesticus
Length: 414  
Fragment?: false
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Protein
Q9JHC9
Organism: Mus musculus/domesticus
Length: 593  
Fragment?: false
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Protein
Q99JB6
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: false
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Protein
Q61286
Organism: Mus musculus/domesticus
Length: 706  
Fragment?: false
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Protein
P22091
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
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Protein
Q8CDC0
Organism: Mus musculus/domesticus
Length: 389  
Fragment?: false
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Publication
23527555 | J:213092
First Author: Wang SS
Year: 2013
Journal: FEBS J
Title: Gdf6 induces commitment of pluripotent mesenchymal C3H10T1/2 cells to the adipocyte lineage.
Volume: 280
Issue: 11
Pages: 2644-51
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Publication
26774823 | J:229306
First Author: Indjeian VB
Year: 2016
Journal: Cell
Title: Evolving New Skeletal Traits by cis-Regulatory Changes in Bone Morphogenetic Proteins.
Volume: 164
Issue: 1-2
Pages: 45-56
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Protein Domain
IPR016554 | TF_Runt-rel_RUNX
Type: Family
Description: This group represents runt-related transcription factors RUNX. The RUNX family of transcription factors plays important roles in hematopoiesis, neurogenesis, bone development, and segmentation in vertebrate embryos. RUNX1 and its Xenopus and Drosophila homologues appear to determine hematopoietic cell fate during development [].
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HT Experiment
E-GEOD-4411 | Transcription profiling of mouse denervated muscle from runx1f mutants vs. controls
Series Id: GSE4411
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Allele
Runx1<tm2Spe> | MGI:2668479
Name: runt related transcription factor 1; targeted mutation 2, Nancy A Speck
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Runx1<tm2(Runx1)Toku> | MGI:3029983
Name: runt related transcription factor 1; targeted mutation 2, Tsukasa Okuda
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Allele
Ly6a<tm2(RUNX1)Grau> | MGI:3510673
Name: lymphocyte antigen 6 family member A; targeted mutation 2, Timothy A Graubert
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Reporter
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Allele
Runx1<tm1(RUNX1)Gcg> | MGI:3621479
Name: runt related transcription factor 1; targeted mutation 1, Gerard C Grosveld
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Publication
18003603 | J:130132
First Author: Ohno S
Year: 2008
Journal: Int Immunol
Title: Runx proteins are involved in regulation of CD122, Ly49 family and IFN-gamma expression during NK cell differentiation.
Volume: 20
Issue: 1
Pages: 71-9
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Allele
Etv6<tm1(RUNX1)Haho> | MGI:4355899
Name: ets variant 6; targeted mutation 1, Hanno Hock
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, No functional change
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Allele
Ts(17<16>;EIF1AX-Xist)67Jlaw | MGI:7579215
Name: trisomy, Chr 16 translocation to Chr 17, Jeanne Lawrence 67
Allele Type: Endonuclease-mediated
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Runx1/Runx1
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Spi1/Spi1
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Runx1/Runx1<+>
Background: involves: 129P2/OlaHsd * C3H * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Runx1/Runx1<+>
Background: involves: 129P2/OlaHsd * C3H/HeJ * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Runx1-GFP)#Itan/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Runx1/Runx1
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Publication
36912240 | J:335268
 
First Author: Swift SK
Year: 2023
Journal: Development
Title: Cardiomyocyte ploidy is dynamic during postnatal development and varies across genetic backgrounds.
Volume: 150
Issue: 7
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Protein Domain
IPR034632 | MYEF2
Type: Family
Description: MEF-2 (also known as MyEF-2) is a sequence-specific single-stranded DNA (ssDNA) binding protein that binds specifically to ssDNA derived from the proximal (MB1) element of the myelin basic protein (MBP) promoter and represses transcription of the MBP gene [, ]. MEF-2 contains two RNA recognition motifs (RRMs). MEF-2 is also a binding partner of RUNX1 during erythropoiesis, which is bound in undifferentiated cells and lost upon differentiation [].
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Protein Coding Gene
MGI:1328366 | Smarcb1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1915344 | Smarcc2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1927347 | Smarce1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1933621 | Smarcd2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1923998 | Pbrm1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1914307 | Yaf2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1933623 | Smarcd1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:99603 | Smarca2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2139971 | Prmt6
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1935147 | Arid1a
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1336991 | Trp73
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1933548 | Actl6b
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:95662 | Gata2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1929059 | Rybp
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1095400 | Zfpm1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1203524 | Smarcc1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
E9Q4N7
Organism: Mus musculus/domesticus
Length: 2306  
Fragment?: false
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Protein
Q99MR0
Organism: Mus musculus/domesticus
Length: 426  
Fragment?: false
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Protein
A2BH40
Organism: Mus musculus/domesticus
Length: 2283  
Fragment?: false
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Protein
Q6NZB1
Organism: Mus musculus/domesticus
Length: 378  
Fragment?: false
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Protein
Q8BSQ9
Organism: Mus musculus/domesticus
Length: 1634  
Fragment?: false
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Protein
Q9JJP2
Organism: Mus musculus/domesticus
Length: 631  
Fragment?: false
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Protein
O09100
Organism: Mus musculus/domesticus
Length: 480  
Fragment?: false
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Protein
Q8CCI5
Organism: Mus musculus/domesticus
Length: 228  
Fragment?: false
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Protein
O35615
Organism: Mus musculus/domesticus
Length: 995  
Fragment?: false
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Protein
Q61466
Organism: Mus musculus/domesticus
Length: 515  
Fragment?: false
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Protein
Q6PDG5
Organism: Mus musculus/domesticus
Length: 1213  
Fragment?: false
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Protein
P97496
Organism: Mus musculus/domesticus
Length: 1104  
Fragment?: false
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Protein
Q99JR8
Organism: Mus musculus/domesticus
Length: 531  
Fragment?: false
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Protein
Q6DIC0
Organism: Mus musculus/domesticus
Length: 1577  
Fragment?: false
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Protein
O54941
Organism: Mus musculus/domesticus
Length: 411  
Fragment?: false
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Protein
Q9Z0H3
Organism: Mus musculus/domesticus
Length: 385  
Fragment?: false
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Protein
Q99LW6
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: false
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Allele
Runx1<tm2Dow> | MGI:2387300
 
Name: runt related transcription factor 1; targeted mutation 2, James R Downing
Allele Type: Targeted
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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