| Type |
Details |
Score |
| Publication |
| First Author: |
Wang A |
| Year: |
2010 |
| Journal: |
Am J Pathol |
| Title: |
Exacerbation of oxazolone colitis by infection with the helminth Hymenolepis diminuta: involvement of IL-5 and eosinophils. |
| Volume: |
177 |
| Issue: |
6 |
| Pages: |
2850-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Alexaki A |
| Year: |
2014 |
| Journal: |
J Lipid Res |
| Title: |
Autophagy regulates sphingolipid levels in the liver. |
| Volume: |
55 |
| Issue: |
12 |
| Pages: |
2521-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang D |
| Year: |
2007 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A sperm-specific Na+/H+ exchanger (sNHE) is critical for expression and in vivo bicarbonate regulation of the soluble adenylyl cyclase (sAC). |
| Volume: |
104 |
| Issue: |
22 |
| Pages: |
9325-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fuss J |
| Year: |
2015 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A runner's high depends on cannabinoid receptors in mice. |
| Volume: |
112 |
| Issue: |
42 |
| Pages: |
13105-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wilbanks A |
| Year: |
2001 |
| Journal: |
J Immunol |
| Title: |
Expression cloning of the STRL33/BONZO/TYMSTRligand reveals elements of CC, CXC, and CX3C chemokines. |
| Volume: |
166 |
| Issue: |
8 |
| Pages: |
5145-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kriegel MA |
| Year: |
2009 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
E3 ubiquitin ligase GRAIL controls primary T cell activation and oral tolerance. |
| Volume: |
106 |
| Issue: |
39 |
| Pages: |
16770-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Martinez EC |
| Year: |
2023 |
| Journal: |
Gene Ther |
| Title: |
Targeting mAKAPβ expression as a therapeutic approach for ischemic cardiomyopathy. |
| Volume: |
30 |
| Issue: |
7-8 |
| Pages: |
543-551 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Seidah NG |
| Year: |
1999 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization. |
| Volume: |
96 |
| Issue: |
4 |
| Pages: |
1321-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fantin A |
| Year: |
2015 |
| Journal: |
Cell Rep |
| Title: |
NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells. |
| Volume: |
11 |
| Issue: |
10 |
| Pages: |
1577-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Quinlan JJ |
| Year: |
1998 |
| Journal: |
Anesthesiology |
| Title: |
Anesthesia sensitivity in mice that lack the beta3 subunit of the gamma-aminobutyric acid type A receptor. |
| Volume: |
88 |
| Issue: |
3 |
| Pages: |
775-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
He W |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction. |
| Volume: |
107 |
| Issue: |
49 |
| Pages: |
21110-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hilliard TN |
| Year: |
2008 |
| Journal: |
Am J Respir Cell Mol Biol |
| Title: |
Nasal abnormalities in cystic fibrosis mice independent of infection and inflammation. |
| Volume: |
39 |
| Issue: |
1 |
| Pages: |
19-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marsh L |
| Year: |
1988 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
STE2 protein of Saccharomyces kluyveri is a member of the rhodopsin/beta-adrenergic receptor family and is responsible for recognition of the peptide ligand alpha factor. |
| Volume: |
85 |
| Issue: |
11 |
| Pages: |
3855-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bergtold A |
| Year: |
2006 |
| Journal: |
J Immunol |
| Title: |
FcR-bearing myeloid cells are responsible for triggering murine lupus nephritis. |
| Volume: |
177 |
| Issue: |
10 |
| Pages: |
7287-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ma A |
| Year: |
1995 |
| Journal: |
J Exp Med |
| Title: |
T cells, but not B cells, are required for bowel inflammation in interleukin 2-deficient mice. |
| Volume: |
182 |
| Issue: |
5 |
| Pages: |
1567-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Matsukawa A |
| Year: |
2001 |
| Journal: |
J Exp Med |
| Title: |
Pivotal role of signal transducer and activator of transcription (Stat)4 and Stat6 in the innate immune response during sepsis. |
| Volume: |
193 |
| Issue: |
6 |
| Pages: |
679-88 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wittke A |
| Year: |
2004 |
| Journal: |
J Immunol |
| Title: |
Vitamin D receptor-deficient mice fail to develop experimental allergic asthma. |
| Volume: |
173 |
| Issue: |
5 |
| Pages: |
3432-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rácz A |
| Year: |
2009 |
| Journal: |
J Neurosci |
| Title: |
Augmented hippocampal ripple oscillations in mice with reduced fast excitation onto parvalbumin-positive cells. |
| Volume: |
29 |
| Issue: |
8 |
| Pages: |
2563-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Varthaman A |
| Year: |
2011 |
| Journal: |
PLoS One |
| Title: |
Physiological induction of regulatory Qa-1-restricted CD8+ T cells triggered by endogenous CD4+ T cell responses. |
| Volume: |
6 |
| Issue: |
6 |
| Pages: |
e21628 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Conway SJ |
| Year: |
1994 |
| Journal: |
Mamm Genome |
| Title: |
Y353/B: a candidate multiple-copy spermiogenesis gene on the mouse Y chromosome. |
| Volume: |
5 |
| Issue: |
4 |
| Pages: |
203-10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thiru A |
| Year: |
2004 |
| Journal: |
EMBO J |
| Title: |
Structural basis of HP1/PXVXL motif peptide interactions and HP1 localisation to heterochromatin. |
| Volume: |
23 |
| Issue: |
3 |
| Pages: |
489-99 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hänninen A |
| Year: |
2007 |
| Journal: |
Am J Pathol |
| Title: |
Islet beta-cell-specific T cells can use different homing mechanisms to infiltrate and destroy pancreatic islets. |
| Volume: |
170 |
| Issue: |
1 |
| Pages: |
240-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shukla A |
| Year: |
2017 |
| Journal: |
EMBO J |
| Title: |
Calcium-permeable AMPA receptors and silent synapses in cocaine-conditioned place preference. |
| Volume: |
36 |
| Issue: |
4 |
| Pages: |
458-474 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nakane A |
| Year: |
1995 |
| Journal: |
Infect Immun |
| Title: |
Endogenous gamma interferon, tumor necrosis factor, and interleukin-6 in Staphylococcus aureus infection in mice. |
| Volume: |
63 |
| Issue: |
4 |
| Pages: |
1165-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yoshida J |
| Year: |
2008 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Inhibition of branching and spine maturation by repulsive guidance molecule in cultured cortical neurons. |
| Volume: |
372 |
| Issue: |
4 |
| Pages: |
725-9 |
|
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•
•
•
•
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| Publication |
| First Author: |
Heep H |
| Year: |
2008 |
| Journal: |
Int J Biol Sci |
| Title: |
Differences in trabecular bone of leptin-deficient ob/ob mice in response to biomechanical loading. |
| Volume: |
4 |
| Issue: |
3 |
| Pages: |
169-75 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bouhidel O |
| Year: |
2008 |
| Journal: |
Am J Physiol Heart Circ Physiol |
| Title: |
Myocardial ischemic postconditioning against ischemia-reperfusion is impaired in ob/ob mice. |
| Volume: |
295 |
| Issue: |
4 |
| Pages: |
H1580-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jürgens HS |
| Year: |
2006 |
| Journal: |
Physiol Genomics |
| Title: |
Hyperphagia, lower body temperature, and reduced running wheel activity precede development of morbid obesity in New Zealand obese mice. |
| Volume: |
25 |
| Issue: |
2 |
| Pages: |
234-41 |
|
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•
•
•
•
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| Publication |
| First Author: |
Daugherty A |
| Year: |
1997 |
| Journal: |
J Clin Invest |
| Title: |
The effects of total lymphocyte deficiency on the extent of atherosclerosis in apolipoprotein E-/- mice. |
| Volume: |
100 |
| Issue: |
6 |
| Pages: |
1575-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Roller A |
| Year: |
2012 |
| Journal: |
J Immunol |
| Title: |
Blockade of phosphatidylinositol 3-kinase PI3Kδ or PI3Kγ reduces IL-17 and ameliorates imiquimod-induced psoriasis-like dermatitis. |
| Volume: |
189 |
| Issue: |
9 |
| Pages: |
4612-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Davis FM |
| Year: |
2021 |
| Journal: |
J Exp Med |
| Title: |
Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms. |
| Volume: |
218 |
| Issue: |
6 |
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•
•
•
•
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| Publication |
| First Author: |
Liu L |
| Year: |
1999 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Hemoglobin induction in mouse macrophages. |
| Volume: |
96 |
| Issue: |
12 |
| Pages: |
6643-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Arakawa H |
| Year: |
1998 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Identification and characterization of the ARP1 gene, a target for the human acute leukemia ALL1 gene. |
| Volume: |
95 |
| Issue: |
8 |
| Pages: |
4573-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ito-Ishida A |
| Year: |
2015 |
| Journal: |
Neuron |
| Title: |
Loss of MeCP2 in Parvalbumin-and Somatostatin-Expressing Neurons in Mice Leads to Distinct Rett Syndrome-like Phenotypes. |
| Volume: |
88 |
| Issue: |
4 |
| Pages: |
651-8 |
|
•
•
•
•
•
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| Publication |
| First Author: |
Chow A |
| Year: |
2021 |
| Journal: |
Cancer Cell |
| Title: |
Tim-4(+) cavity-resident macrophages impair anti-tumor CD8(+) TÂ cell immunity. |
| Volume: |
39 |
| Issue: |
7 |
| Pages: |
973-988.e9 |
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•
•
•
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| Publication |
| First Author: |
Rousselle A |
| Year: |
2013 |
| Journal: |
J Clin Invest |
| Title: |
CXCL5 limits macrophage foam cell formation in atherosclerosis. |
| Volume: |
123 |
| Issue: |
3 |
| Pages: |
1343-7 |
|
•
•
•
•
•
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| Publication |
| First Author: |
Ariëns RA |
| Year: |
2000 |
| Journal: |
Blood |
| Title: |
The factor XIII V34L polymorphism accelerates thrombin activation of factor XIII and affects cross-linked fibrin structure. |
| Volume: |
96 |
| Issue: |
3 |
| Pages: |
988-95 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
This entry includes the A chain of coagulation factor XIII (FXIIIa; ). FXIII is a heterotetramer consisting of two A and two B chains. FXIII is activated by thrombin, and activated FXIII (FXIIIa) covalently cross-links the fibrin chains, making an insoluble clot. Activation of FXIII involves thrombin-induced cleavage of the peptide bond between Arg37 and Gly38 of the A subunit, resulting in the release of an N-terminal activation peptide. In a second step, calcium induces dissociation of the A-subunit dimer from the B subunit. Activated FXIIIa catalyzes the introduction of gamma-glutamyl-epsilon-lysine peptide bonds between fibrin gamma- and alpha-chains. The B subunit serve a carrier function for the A subunit in plasma []. Interestingly, FXIIIa is also present in the cytoplasm of platelets, monocytes, monocyte-derived macrophages, dendritic cells, chondrocytes, osteoblasts, and osteocytes. It may be invovled in wound healing process and maintaining pregnancy []. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee CS |
| Year: |
2002 |
| Journal: |
Diabetes |
| Title: |
Foxa2 controls Pdx1 gene expression in pancreatic beta-cells in vivo. |
| Volume: |
51 |
| Issue: |
8 |
| Pages: |
2546-51 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kotlyarov A |
| Year: |
2002 |
| Journal: |
Mol Cell Biol |
| Title: |
Distinct cellular functions of MK2. |
| Volume: |
22 |
| Issue: |
13 |
| Pages: |
4827-35 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawakita A |
| Year: |
2008 |
| Journal: |
PLoS One |
| Title: |
Nicotine acts on growth plate chondrocytes to delay skeletal growth through the alpha7 neuronal nicotinic acetylcholine receptor. |
| Volume: |
3 |
| Issue: |
12 |
| Pages: |
e3945 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hartner A |
| Year: |
2006 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
Role of fibrillin-1 in hypertensive and diabetic glomerular disease. |
| Volume: |
290 |
| Issue: |
6 |
| Pages: |
F1329-36 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Riese A |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
Epidermal expression of neuropilin 1 protects murine keratinocytes from UVB-induced apoptosis. |
| Volume: |
7 |
| Issue: |
12 |
| Pages: |
e50944 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hernandez A |
| Year: |
2002 |
| Journal: |
Endocrinology |
| Title: |
The gene locus encoding iodothyronine deiodinase type 3 (Dio3) is imprinted in the fetus and expresses antisense transcripts. |
| Volume: |
143 |
| Issue: |
11 |
| Pages: |
4483-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sanz-Alcázar A |
| Year: |
2024 |
| Journal: |
Redox Biol |
| Title: |
Deciphering the ferroptosis pathways in dorsal root ganglia of Friedreich ataxia models. The role of LKB1/AMPK, KEAP1, and GSK3β in the impairment of the NRF2 response. |
| Volume: |
76 |
|
| Pages: |
103339 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
953
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
926
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
62
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
40
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
966
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nagdas S |
| Year: |
2019 |
| Journal: |
Cell Rep |
| Title: |
Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth. |
| Volume: |
28 |
| Issue: |
7 |
| Pages: |
1845-1859.e5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stohl W |
| Year: |
2020 |
| Journal: |
J Immunol |
| Title: |
Promotion of T Regulatory Cells in Mice by B Cells and BAFF. |
| Volume: |
204 |
| Issue: |
9 |
| Pages: |
2416-2428 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chiot A |
| Year: |
2020 |
| Journal: |
Nat Neurosci |
| Title: |
Modifying macrophages at the periphery has the capacity to change microglial reactivity and to extend ALS survival. |
| Volume: |
23 |
| Issue: |
11 |
| Pages: |
1339-1351 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ramadori G |
| Year: |
2015 |
| Journal: |
Cell Metab |
| Title: |
Diet-induced unresolved ER stress hinders KRAS-driven lung tumorigenesis. |
| Volume: |
21 |
| Issue: |
1 |
| Pages: |
117-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Minn AH |
| Year: |
2005 |
| Journal: |
Mol Endocrinol |
| Title: |
Increased insulin translation from an insulin splice-variant overexpressed in diabetes, obesity, and insulin resistance. |
| Volume: |
19 |
| Issue: |
3 |
| Pages: |
794-803 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Anderson MP |
| Year: |
2005 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Thalamic Cav3.1 T-type Ca2+ channel plays a crucial role in stabilizing sleep. |
| Volume: |
102 |
| Issue: |
5 |
| Pages: |
1743-8 |
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•
•
•
•
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| Publication |
| First Author: |
Soumillion A |
| Year: |
1997 |
| Journal: |
Anim Genet |
| Title: |
Assignment of the porcine loci for MYOD1 to chromosome 2 and MYF5 to chromosome 5. |
| Volume: |
28 |
| Issue: |
1 |
| Pages: |
37-8 |
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•
•
•
•
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| Publication |
| First Author: |
Oyoshi MK |
| Year: |
2012 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Eosinophil-derived leukotriene C4 signals via type 2 cysteinyl leukotriene receptor to promote skin fibrosis in a mouse model of atopic dermatitis. |
| Volume: |
109 |
| Issue: |
13 |
| Pages: |
4992-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Galán A |
| Year: |
2017 |
| Journal: |
Cell Death Dis |
| Title: |
In retinitis pigmentosa TrkC.T1-dependent vectorial Erk activity upregulates glial TNF-α, causing selective neuronal death. |
| Volume: |
8 |
| Issue: |
12 |
| Pages: |
3222 |
|
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•
•
•
•
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| Publication |
| First Author: |
Sebastian A |
| Year: |
2017 |
| Journal: |
PLoS One |
| Title: |
Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts. |
| Volume: |
12 |
| Issue: |
11 |
| Pages: |
e0188264 |
|
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•
•
•
•
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| Publication |
| First Author: |
Kito-Shingaki A |
| Year: |
2014 |
| Journal: |
Chem Senses |
| Title: |
Expression of GAD67 and Dlx5 in the taste buds of mice genetically lacking Mash1. |
| Volume: |
39 |
| Issue: |
5 |
| Pages: |
403-14 |
|
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•
•
•
•
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| Publication |
| First Author: |
Noh K |
| Year: |
2017 |
| Journal: |
Cell Rep |
| Title: |
Differential Effects of EGFL6 on Tumor versus Wound Angiogenesis. |
| Volume: |
21 |
| Issue: |
10 |
| Pages: |
2785-2795 |
|
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•
•
•
•
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| Publication |
| First Author: |
Bafica A |
| Year: |
2006 |
| Journal: |
J Immunol |
| Title: |
Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection. |
| Volume: |
177 |
| Issue: |
6 |
| Pages: |
3515-9 |
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•
•
•
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| Publication |
| First Author: |
Jacobi A |
| Year: |
2015 |
| Journal: |
EMBO J |
| Title: |
FGF22 signaling regulates synapse formation during post-injury remodeling of the spinal cord. |
| Volume: |
34 |
| Issue: |
9 |
| Pages: |
1231-43 |
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•
•
•
•
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| Publication |
| First Author: |
Dandoy F |
| Year: |
1984 |
| Journal: |
J Exp Med |
| Title: |
Linkage analysis of the murine interferon-alpha locus on chromosome 4. |
| Volume: |
160 |
| Issue: |
1 |
| Pages: |
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