| Type |
Details |
Score |
| Publication |
| First Author: |
Cen H |
| Year: |
1993 |
| Journal: |
Mol Cell Biol |
| Title: |
Regulated and constitutive activity by CDC25Mm (GRF), a Ras-specific exchange factor. |
| Volume: |
13 |
| Issue: |
12 |
| Pages: |
7718-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Crespo P |
| Year: |
2011 |
| Journal: |
Bioarchitecture |
| Title: |
Ras and Rho GTPases on the move: The RasGRF connection. |
| Volume: |
1 |
| Issue: |
4 |
| Pages: |
200-204 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fernández-Medarde A |
| Year: |
2011 |
| Journal: |
Biochim Biophys Acta |
| Title: |
The RasGrf family of mammalian guanine nucleotide exchange factors. |
| Volume: |
1815 |
| Issue: |
2 |
| Pages: |
170-88 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Faghihi MA |
| Year: |
2010 |
| Journal: |
PLoS One |
| Title: |
RNAi screen indicates widespread biological function for human natural antisense transcripts. |
| Volume: |
5 |
| Issue: |
10 |
|
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Serine/threonine-protein kinase MRCK (myotonic dystrophy kinase-related CDC42-binding kinase) is an serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in actin-myosin regulation and activities including cell adhesion, motility and invasion [, ]. Three isoforms have been described in mammals: alpha, beta and gamma [, ]. This entry represent the serine/threonine-protein kinase MRCK alpha. It also includes the Drosophila homologue Genghis khan (Gek) [, ]. |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Formin-binding protein 1-like (FNBP1L, also known as Toca-1) is part of the Toca-1-N-WASP complex that induces the formation of filopodia and endocytic vesicles []. FNBP1L consists of an F-BAR domain, a Cdc42 binding site and an SH3 domain []. It belongs to the CIP4 (Cdc42 interacting protein-4) subfamily of the F-BAR (F for FCH, Fer-CIP4 homology domain) protein family. The F-BAR proteins have been implicated in cell membrane processes such as membrane invagination, tubulation and endocytosis []. |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Serine/threonine-protein kinase MRCK (myotonic dystrophy kinase-related CDC42-binding kinase) is an serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in actin-myosin regulation and activities including cell adhesion, motility and invasion [, ]. Three isoforms have been described in mammals: alpha, beta and gamma [, ]. This entry represent the serine/threonine-protein kinase MRCK beta. It may have important roles in tumour progression []. |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Cell cycle progression protein 1 (CCPG1), also known as cell cycle progression restoration protein 8 (CPR8) [], is a scaffold protein that interacts with the Rho guanine nucleotide exchange factor Dbs and modulates its exchange specificity. CCPG1 binds to the Dbl homology/pleckstrin homology domain tandem motif of Dbs and inhibits its exchange activity toward RhoA, but not Cdc42 []. CCPG1 may be involved in cell cycle regulation []. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Worthylake DK |
| Year: |
2004 |
| Journal: |
Structure |
| Title: |
Crystal structure of the DH/PH fragment of Dbs without bound GTPase. |
| Volume: |
12 |
| Issue: |
6 |
| Pages: |
1078-86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ieguchi K |
| Year: |
2007 |
| Journal: |
J Biol Chem |
| Title: |
Role of the guanine nucleotide exchange factor Ost in negative regulation of receptor endocytosis by the small GTPase Rac1. |
| Volume: |
282 |
| Issue: |
32 |
| Pages: |
23296-305 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
118
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
195
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
155
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
338
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
178
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Symons M |
| Year: |
1996 |
| Journal: |
Cell |
| Title: |
Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization. |
| Volume: |
84 |
| Issue: |
5 |
| Pages: |
723-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thompson G |
| Year: |
1998 |
| Journal: |
Biochemistry |
| Title: |
Delineation of the Cdc42/Rac-binding domain of p21-activated kinase. |
| Volume: |
37 |
| Issue: |
21 |
| Pages: |
7885-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lei M |
| Year: |
2000 |
| Journal: |
Cell |
| Title: |
Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch. |
| Volume: |
102 |
| Issue: |
3 |
| Pages: |
387-97 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hoffman GR |
| Year: |
2000 |
| Journal: |
Cell |
| Title: |
Flipping the switch: the structural basis for signaling through the CRIB motif. |
| Volume: |
102 |
| Issue: |
4 |
| Pages: |
403-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ng Y |
| Year: |
2004 |
| Journal: |
J Biol Chem |
| Title: |
Expression of the human myotonic dystrophy kinase-related Cdc42-binding kinase gamma is regulated by promoter DNA methylation and Sp1 binding. |
| Volume: |
279 |
| Issue: |
33 |
| Pages: |
34156-64 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tan I |
| Year: |
2008 |
| Journal: |
Cell |
| Title: |
A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow. |
| Volume: |
135 |
| Issue: |
1 |
| Pages: |
123-36 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tan I |
| Year: |
2011 |
| Journal: |
FEBS Lett |
| Title: |
Chelerythrine perturbs lamellar actomyosin filaments by selective inhibition of myotonic dystrophy kinase-related Cdc42-binding kinase. |
| Volume: |
585 |
| Issue: |
9 |
| Pages: |
1260-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Unbekandt M |
| Year: |
2014 |
| Journal: |
J Mol Med (Berl) |
| Title: |
The actin-myosin regulatory MRCK kinases: regulation, biological functions and associations with human cancer. |
| Volume: |
92 |
| Issue: |
3 |
| Pages: |
217-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bu W |
| Year: |
2009 |
| Journal: |
J Biol Chem |
| Title: |
The Toca-1-N-WASP complex links filopodial formation to endocytosis. |
| Volume: |
284 |
| Issue: |
17 |
| Pages: |
11622-36 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu Z |
| Year: |
2009 |
| Journal: |
J Biol Chem |
| Title: |
The rho-specific guanine nucleotide exchange factor Dbs regulates breast cancer cell migration. |
| Volume: |
284 |
| Issue: |
23 |
| Pages: |
15771-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kostenko EV |
| Year: |
2005 |
| Journal: |
J Biol Chem |
| Title: |
The Sec14 homology domain regulates the cellular distribution and transforming activity of the Rho-specific guanine nucleotide exchange factor Dbs. |
| Volume: |
280 |
| Issue: |
4 |
| Pages: |
2807-17 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Klinger MB |
| Year: |
2004 |
| Journal: |
Eur J Immunol |
| Title: |
The RhoA- and CDC42-specific exchange factor Dbs promotes expansion of immature thymocytes and deletion of double-positive and single-positive thymocytes. |
| Volume: |
34 |
| Issue: |
3 |
| Pages: |
806-816 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Salazar MA |
| Year: |
2003 |
| Journal: |
J Biol Chem |
| Title: |
Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton. |
| Volume: |
278 |
| Issue: |
49 |
| Pages: |
49031-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim AS |
| Year: |
2000 |
| Journal: |
Nature |
| Title: |
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein. |
| Volume: |
404 |
| Issue: |
6774 |
| Pages: |
151-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hori K |
| Year: |
2014 |
| Journal: |
Cell Rep |
| Title: |
Cytoskeletal regulation by AUTS2 in neuronal migration and neuritogenesis. |
| Volume: |
9 |
| Issue: |
6 |
| Pages: |
2166-79 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ursino GM |
| Year: |
2020 |
| Journal: |
EMBO Rep |
| Title: |
ABCA12 regulates insulin secretion from β-cells. |
| Volume: |
21 |
| Issue: |
3 |
| Pages: |
e48692 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Alberts AS |
| Year: |
1998 |
| Journal: |
EMBO J |
| Title: |
Activation of RhoA and SAPK/JNK signalling pathways by the RhoA-specific exchange factor mNET1. |
| Volume: |
17 |
| Issue: |
14 |
| Pages: |
4075-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu K |
| Year: |
2011 |
| Journal: |
Dev Cell |
| Title: |
Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signaling. |
| Volume: |
20 |
| Issue: |
4 |
| Pages: |
526-39 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Park SH |
| Year: |
1995 |
| Journal: |
Oncogene |
| Title: |
A putative effector of Ral has homology to Rho/Rac GTPase activating proteins. |
| Volume: |
11 |
| Issue: |
11 |
| Pages: |
2349-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kholmanskikh SS |
| Year: |
2003 |
| Journal: |
J Neurosci |
| Title: |
Disregulated RhoGTPases and actin cytoskeleton contribute to the migration defect in Lis1-deficient neurons. |
| Volume: |
23 |
| Issue: |
25 |
| Pages: |
8673-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
He X |
| Year: |
2013 |
| Journal: |
Structure |
| Title: |
Structural basis for autoinhibition of the guanine nucleotide exchange factor FARP2. |
| Volume: |
21 |
| Issue: |
3 |
| Pages: |
355-64 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Qu J |
| Year: |
2003 |
| Journal: |
Mol Cell Biol |
| Title: |
PAK4 kinase is essential for embryonic viability and for proper neuronal development. |
| Volume: |
23 |
| Issue: |
20 |
| Pages: |
7122-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Majmundar AJ |
| Year: |
2021 |
| Journal: |
Sci Adv |
| Title: |
Recessive NOS1AP variants impair actin remodeling and cause glomerulopathy in humans and mice. |
| Volume: |
7 |
| Issue: |
1 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Snyder JT |
| Year: |
2002 |
| Journal: |
Nat Struct Biol |
| Title: |
Structural basis for the selective activation of Rho GTPases by Dbl exchange factors. |
| Volume: |
9 |
| Issue: |
6 |
| Pages: |
468-75 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Raghunathan A |
| Year: |
2001 |
| Journal: |
Exp Cell Res |
| Title: |
Functional analysis of B144/LST1: a gene in the tumor necrosis factor cluster that induces formation of long filopodia in eukaryotic cells. |
| Volume: |
268 |
| Issue: |
2 |
| Pages: |
230-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cory GO |
| Year: |
2002 |
| Journal: |
J Biol Chem |
| Title: |
Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome protein. |
| Volume: |
277 |
| Issue: |
47 |
| Pages: |
45115-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tapon N |
| Year: |
1998 |
| Journal: |
EMBO J |
| Title: |
A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways. |
| Volume: |
17 |
| Issue: |
5 |
| Pages: |
1395-404 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nasu-Nishimura Y |
| Year: |
2006 |
| Journal: |
Genes Cells |
| Title: |
Role of the Rho GTPase-activating protein RICS in neurite outgrowth. |
| Volume: |
11 |
| Issue: |
6 |
| Pages: |
607-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tao W |
| Year: |
2001 |
| Journal: |
Genes Dev |
| Title: |
Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1. |
| Volume: |
15 |
| Issue: |
14 |
| Pages: |
1796-807 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Matsuo N |
| Year: |
2003 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Roles of STEF/Tiam1, guanine nucleotide exchange factors for Rac1, in regulation of growth cone morphology. |
| Volume: |
24 |
| Issue: |
1 |
| Pages: |
69-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim SM |
| Year: |
2011 |
| Journal: |
Exp Cell Res |
| Title: |
Control of growth cone motility and neurite outgrowth by SPIN90. |
| Volume: |
317 |
| Issue: |
16 |
| Pages: |
2276-87 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brantley-Sieders DM |
| Year: |
2009 |
| Journal: |
Mol Cancer Res |
| Title: |
Host deficiency in Vav2/3 guanine nucleotide exchange factors impairs tumor growth, survival, and angiogenesis in vivo. |
| Volume: |
7 |
| Issue: |
5 |
| Pages: |
615-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wei C |
| Year: |
2008 |
| Journal: |
Nat Med |
| Title: |
Modification of kidney barrier function by the urokinase receptor. |
| Volume: |
14 |
| Issue: |
1 |
| Pages: |
55-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cheng CM |
| Year: |
2003 |
| Journal: |
J Neurosci Res |
| Title: |
Insulin-like growth factor 1 is essential for normal dendritic growth. |
| Volume: |
73 |
| Issue: |
1 |
| Pages: |
1-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schreck C |
| Year: |
2017 |
| Journal: |
J Exp Med |
| Title: |
Niche WNT5A regulates the actin cytoskeleton during regeneration of hematopoietic stem cells. |
| Volume: |
214 |
| Issue: |
1 |
| Pages: |
165-181 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Miyamura N |
| Year: |
2017 |
| Journal: |
Nat Commun |
| Title: |
YAP determines the cell fate of injured mouse hepatocytes in vivo. |
| Volume: |
8 |
|
| Pages: |
16017 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bijata M |
| Year: |
2017 |
| Journal: |
Cell Rep |
| Title: |
Synaptic Remodeling Depends on Signaling between Serotonin Receptors and the Extracellular Matrix. |
| Volume: |
19 |
| Issue: |
9 |
| Pages: |
1767-1782 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tu Z |
| Year: |
2022 |
| Journal: |
Cell Rep |
| Title: |
Autism-associated chromatin remodeler CHD8 regulates erythroblast cytokinesis and fine-tunes the balance of Rho GTPase signaling. |
| Volume: |
40 |
| Issue: |
2 |
| Pages: |
111072 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kunimura K |
| Year: |
2019 |
| Journal: |
Cell Rep |
| Title: |
S100A4 Protein Is Essential for the Development of Mature Microfold Cells in Peyer's Patches. |
| Volume: |
29 |
| Issue: |
9 |
| Pages: |
2823-2834.e7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ye S |
| Year: |
2016 |
| Journal: |
Int J Biol Sci |
| Title: |
LIS1 Regulates Osteoclastogenesis through Modulation of M-SCF and RANKL Signaling Pathways and CDC42. |
| Volume: |
12 |
| Issue: |
12 |
| Pages: |
1488-1499 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hara-Chikuma M |
| Year: |
2012 |
| Journal: |
J Exp Med |
| Title: |
Chemokine-dependent T cell migration requires aquaporin-3-mediated hydrogen peroxide uptake. |
| Volume: |
209 |
| Issue: |
10 |
| Pages: |
1743-52 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rehn M |
| Year: |
2022 |
| Journal: |
Cell Rep |
| Title: |
PTBP1 promotes hematopoietic stem cell maintenance and red blood cell development by ensuring sufficient availability of ribosomal constituents. |
| Volume: |
39 |
| Issue: |
6 |
| Pages: |
110793 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nayak RC |
| Year: |
2019 |
| Journal: |
Nat Commun |
| Title: |
The signaling axis atypical protein kinase C λ/ι-Satb2 mediates leukemic transformation of B-cell progenitors. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
46 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Grande-GarcÃa A |
| Year: |
2007 |
| Journal: |
J Cell Biol |
| Title: |
Caveolin-1 regulates cell polarization and directional migration through Src kinase and Rho GTPases. |
| Volume: |
177 |
| Issue: |
4 |
| Pages: |
683-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee HS |
| Year: |
2015 |
| Journal: |
Mol Cell Biol |
| Title: |
Protein tyrosine phosphatase-PEST and β8 integrin regulate spatiotemporal patterns of RhoGDI1 activation in migrating cells. |
| Volume: |
35 |
| Issue: |
8 |
| Pages: |
1401-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tetreault MP |
| Year: |
2016 |
| Journal: |
Sci Rep |
| Title: |
KLF4 transcriptionally activates non-canonical WNT5A to control epithelial stratification. |
| Volume: |
6 |
|
| Pages: |
26130 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Haubert D |
| Year: |
2007 |
| Journal: |
EMBO J |
| Title: |
PtdIns(4,5)P-restricted plasma membrane localization of FAN is involved in TNF-induced actin reorganization. |
| Volume: |
26 |
| Issue: |
14 |
| Pages: |
3308-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Du X |
| Year: |
2020 |
| Journal: |
J Exp Med |
| Title: |
Mevalonate metabolism-dependent protein geranylgeranylation regulates thymocyte egress. |
| Volume: |
217 |
| Issue: |
2 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Phee H |
| Year: |
2014 |
| Journal: |
Elife |
| Title: |
Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation. |
| Volume: |
3 |
|
| Pages: |
e02270 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hirsch E |
| Year: |
2002 |
| Journal: |
Mol Cell Biol |
| Title: |
Defective dendrite elongation but normal fertility in mice lacking the Rho-like GTPase activator Dbl. |
| Volume: |
22 |
| Issue: |
9 |
| Pages: |
3140-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bernadzki KM |
| Year: |
2020 |
| Journal: |
Front Mol Neurosci |
| Title: |
Arhgef5 Binds α-Dystrobrevin 1 and Regulates Neuromuscular Junction Integrity. |
| Volume: |
13 |
|
| Pages: |
104 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Martinez-Lopez N |
| Year: |
2023 |
| Journal: |
Nat Cell Biol |
| Title: |
mTORC2-NDRG1-CDC42 axis couples fasting to mitochondrial fission. |
| Volume: |
25 |
| Issue: |
7 |
| Pages: |
989-1003 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tu X |
| Year: |
2020 |
| Journal: |
Sci Rep |
| Title: |
Rac1 is a downstream effector of PKCα in structural synaptic plasticity. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
1777 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Abraham S |
| Year: |
2015 |
| Journal: |
Nat Commun |
| Title: |
A Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia and blood vessel lumen morphogenesis. |
| Volume: |
6 |
|
| Pages: |
7286 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang Q |
| Year: |
2014 |
| Journal: |
J Exp Med |
| Title: |
DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity. |
| Volume: |
211 |
| Issue: |
13 |
| Pages: |
2549-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jung H |
| Year: |
2016 |
| Journal: |
Nat Commun |
| Title: |
Thioredoxin-interacting protein regulates haematopoietic stem cell ageing and rejuvenation by inhibiting p38 kinase activity. |
| Volume: |
7 |
|
| Pages: |
13674 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang L |
| Year: |
2005 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Cdc42GAP regulates c-Jun N-terminal kinase (JNK)-mediated apoptosis and cell number during mammalian perinatal growth. |
| Volume: |
102 |
| Issue: |
38 |
| Pages: |
13484-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sawada Y |
| Year: |
2015 |
| Journal: |
J Exp Med |
| Title: |
Resolvin E1 inhibits dendritic cell migration in the skin and attenuates contact hypersensitivity responses. |
| Volume: |
212 |
| Issue: |
11 |
| Pages: |
1921-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Braun LJ |
| Year: |
2020 |
| Journal: |
Blood |
| Title: |
Platelets docking to VWF prevent leaks during leukocyte extravasation by stimulating Tie-2. |
| Volume: |
136 |
| Issue: |
5 |
| Pages: |
627-639 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fang J |
| Year: |
2017 |
| Journal: |
Nat Immunol |
| Title: |
Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia. |
| Volume: |
18 |
| Issue: |
2 |
| Pages: |
236-245 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim MH |
| Year: |
2009 |
| Journal: |
J Neurosci |
| Title: |
Enhanced NMDA receptor-mediated synaptic transmission, enhanced long-term potentiation, and impaired learning and memory in mice lacking IRSp53. |
| Volume: |
29 |
| Issue: |
5 |
| Pages: |
1586-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chou AM |
| Year: |
2017 |
| Journal: |
Sci Rep |
| Title: |
Redundant functions of I-BAR family members, IRSp53 and IRTKS, are essential for embryonic development. |
| Volume: |
7 |
|
| Pages: |
40485 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Martins R |
| Year: |
2016 |
| Journal: |
Nat Immunol |
| Title: |
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions. |
| Volume: |
17 |
| Issue: |
12 |
| Pages: |
1361-1372 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schlienger S |
| Year: |
2023 |
| Journal: |
Sci Adv |
| Title: |
Genetics of mirror movements identifies a multifunctional complex required for Netrin-1 guidance and lateralization of motor control. |
| Volume: |
9 |
| Issue: |
19 |
| Pages: |
eadd5501 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhong JL |
| Year: |
2003 |
| Journal: |
Dev Dyn |
| Title: |
Pak1 and its T212 phosphorylated form accumulate in neurones and epithelial cells of the developing rodent. |
| Volume: |
228 |
| Issue: |
1 |
| Pages: |
121-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jiménez C |
| Year: |
2000 |
| Journal: |
J Cell Biol |
| Title: |
Role of the PI3K regulatory subunit in the control of actin organization and cell migration. |
| Volume: |
151 |
| Issue: |
2 |
| Pages: |
249-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Park E |
| Year: |
2003 |
| Journal: |
J Biol Chem |
| Title: |
The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42. |
| Volume: |
278 |
| Issue: |
21 |
| Pages: |
19220-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yoshizawa M |
| Year: |
2003 |
| Journal: |
Gene Expr Patterns |
| Title: |
Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain. |
| Volume: |
3 |
| Issue: |
3 |
| Pages: |
375-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Seth A |
| Year: |
2006 |
| Journal: |
J Cell Biol |
| Title: |
Autoinhibition regulates cellular localization and actin assembly activity of the diaphanous-related formins FRLalpha and mDia1. |
| Volume: |
174 |
| Issue: |
5 |
| Pages: |
701-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu Z |
| Year: |
2006 |
| Journal: |
J Biol Chem |
| Title: |
Transformation by the Rho-specific guanine nucleotide exchange factor Dbs requires ROCK I-mediated phosphorylation of myosin light chain. |
| Volume: |
281 |
| Issue: |
23 |
| Pages: |
16043-51 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Feng Q |
| Year: |
2006 |
| Journal: |
Nat Cell Biol |
| Title: |
Cool-1 functions as an essential regulatory node for EGF receptor- and Src-mediated cell growth. |
| Volume: |
8 |
| Issue: |
9 |
| Pages: |
945-56 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Eun SY |
| Year: |
2006 |
| Journal: |
J Immunol |
| Title: |
Cutting edge: rho activation and actin polarization are dependent on plexin-A1 in dendritic cells. |
| Volume: |
177 |
| Issue: |
7 |
| Pages: |
4271-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kang JS |
| Year: |
2008 |
| Journal: |
J Cell Biol |
| Title: |
A Cdo-Bnip-2-Cdc42 signaling pathway regulates p38alpha/beta MAPK activity and myogenic differentiation. |
| Volume: |
182 |
| Issue: |
3 |
| Pages: |
497-507 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang JB |
| Year: |
2009 |
| Journal: |
J Cell Sci |
| Title: |
IQGAP1 regulates cell proliferation through a novel CDC42-mTOR pathway. |
| Volume: |
122 |
| Issue: |
Pt 12 |
| Pages: |
2024-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Koch S |
| Year: |
2009 |
| Journal: |
Mol Biol Cell |
| Title: |
Dkk-1 inhibits intestinal epithelial cell migration by attenuating directional polarization of leading edge cells. |
| Volume: |
20 |
| Issue: |
22 |
| Pages: |
4816-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jossin Y |
| Year: |
2011 |
| Journal: |
Nat Neurosci |
| Title: |
Reelin, Rap1 and N-cadherin orient the migration of multipolar neurons in the developing neocortex. |
| Volume: |
14 |
| Issue: |
6 |
| Pages: |
697-703 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ichida M |
| Year: |
2011 |
| Journal: |
FEBS Lett |
| Title: |
Changes in cell migration of mesenchymal cells during osteogenic differentiation. |
| Volume: |
585 |
| Issue: |
24 |
| Pages: |
4018-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Keestra AM |
| Year: |
2013 |
| Journal: |
Nature |
| Title: |
Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1. |
| Volume: |
496 |
| Issue: |
7444 |
| Pages: |
233-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hanin G |
| Year: |
2014 |
| Journal: |
Hum Mol Genet |
| Title: |
Competing targets of microRNA-608 affect anxiety and hypertension. |
| Volume: |
23 |
| Issue: |
17 |
| Pages: |
4569-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xiang X |
| Year: |
2016 |
| Journal: |
FEBS Lett |
| Title: |
Arhgef1 negatively regulates neurite outgrowth through activation of RhoA signaling pathways. |
| Volume: |
590 |
| Issue: |
17 |
| Pages: |
2940-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kage F |
| Year: |
2017 |
| Journal: |
Nat Commun |
| Title: |
FMNL formins boost lamellipodial force generation. |
| Volume: |
8 |
|
| Pages: |
14832 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Penkert RR |
| Year: |
2004 |
| Journal: |
Nat Struct Mol Biol |
| Title: |
Internal recognition through PDZ domain plasticity in the Par-6-Pals1 complex. |
| Volume: |
11 |
| Issue: |
11 |
| Pages: |
1122-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Deb Roy A |
| Year: |
2017 |
| Journal: |
Nat Commun |
| Title: |
Optogenetic activation of Plexin-B1 reveals contact repulsion between osteoclasts and osteoblasts. |
| Volume: |
8 |
|
| Pages: |
15831 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Diring J |
| Year: |
2019 |
| Journal: |
Nat Cell Biol |
| Title: |
RPEL-family rhoGAPs link Rac/Cdc42 GTP loading to G-actin availability. |
| Volume: |
21 |
| Issue: |
7 |
| Pages: |
845-855 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vohnoutka RB |
| Year: |
2019 |
| Journal: |
Mol Biol Cell |
| Title: |
The focal adhesion scaffold protein Hic-5 regulates vimentin organization in fibroblasts. |
| Volume: |
30 |
| Issue: |
25 |
| Pages: |
3037-3056 |
|
•
•
•
•
•
|