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Search results 2701 to 2800 out of 3022 for Ifng

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Categories

Hits by Pathway

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Hits by Strain

Type Details Score
Protein
O88907
Organism: Mus musculus/domesticus
Length: 651  
Fragment?: false
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Protein
O35718
Organism: Mus musculus/domesticus
Length: 225  
Fragment?: false
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Allele
Map2k3<tm1Flv> | MGI:1857752
Name: mitogen-activated protein kinase kinase 3; targeted mutation 1, Richard A Flavell
Allele Type: Targeted
Attribute String: Null/knockout
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Protein Coding Gene
MGI:103063 | Stat1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P42225
Organism: Mus musculus/domesticus
Length: 749  
Fragment?: false
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Publication
12151339 | J:85266
First Author: Tanaka N
Year: 2002
Journal: EMBO Rep
Title: Differential involvement of p38 mitogen-activated protein kinase kinases MKK3 and MKK6 in T-cell apoptosis.
Volume: 3
Issue: 8
Pages: 785-91
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Publication
12893778 | J:84877
First Author: Brancho D
Year: 2003
Journal: Genes Dev
Title: Mechanism of p38 MAP kinase activation in vivo.
Volume: 17
Issue: 16
Pages: 1969-78
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Publication
19066844 | J:144365
First Author: Lim AK
Year: 2009
Journal: Diabetologia
Title: Role of MKK3-p38 MAPK signalling in the development of type 2 diabetes and renal injury in obese db/db mice.
Volume: 52
Issue: 2
Pages: 347-58
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Publication
21841136 | J:179249
First Author: MacNeil AJ
Year: 2011
Journal: J Immunol
Title: MAPK kinase 3 specifically regulates Fc epsilonRI-mediated IL-4 production by mast cells.
Volume: 187
Issue: 6
Pages: 3374-82
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Publication
19564926 | J:309170
First Author: Wood CD
Year: 2009
Journal: Int J Biol Sci
Title: Nuclear localization of p38 MAPK in response to DNA damage.
Volume: 5
Issue: 5
Pages: 428-37
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Publication
16365149 | J:118826
First Author: Hegazi RA
Year: 2005
Journal: J Exp Med
Title: Carbon monoxide ameliorates chronic murine colitis through a heme oxygenase 1-dependent pathway.
Volume: 202
Issue: 12
Pages: 1703-13
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Publication
17723219 | J:124327
First Author: Lim JH
Year: 2007
Journal: Immunity
Title: Tumor suppressor CYLD regulates acute lung injury in lethal Streptococcus pneumoniae infections.
Volume: 27
Issue: 2
Pages: 349-60
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Publication
19713213 | J:156345
First Author: Nagelin MH
Year: 2009
Journal: J Biol Chem
Title: Murine 12/15-lipoxygenase regulates ATP-binding cassette transporter G1 protein degradation through p38- and JNK2-dependent pathways.
Volume: 284
Issue: 45
Pages: 31303-14
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Strain
MGI:3686785 | B6;129S1-Map2k3<tm1Flv>/J
Attribute String: targeted mutation, mutant stock
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Strain
MGI:3722869 | B6.129S1-Map2k3<tm1Flv>
Attribute String: congenic, mutant strain, targeted mutation
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Publication
10097111 | J:54078
First Author: Wysk M
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression.
Volume: 96
Issue: 7
Pages: 3763-8
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Publication
15778378 | J:97936
First Author: Kim L
Year: 2005
Journal: J Immunol
Title: p38 MAPK autophosphorylation drives macrophage IL-12 production during intracellular infection.
Volume: 174
Issue: 7
Pages: 4178-84
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Publication
25697779 | J:255367
 
First Author: Srivastava A
Year: 2015
Journal: Free Radic Biol Med
Title: MKK3 mediates inflammatory response through modulation of mitochondrial function.
Volume: 83
Pages: 139-48
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Publication
19224920 | J:149257
First Author: Mikkelsen SS
Year: 2009
Journal: J Biol Chem
Title: RIG-I-mediated activation of p38 MAPK is essential for viral induction of interferon and activation of dendritic cells: dependence on TRAF2 and TAK1.
Volume: 284
Issue: 16
Pages: 10774-82
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Publication
10202148 | J:54309
First Author: Lu HT
Year: 1999
Journal: EMBO J
Title: Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice.
Volume: 18
Issue: 7
Pages: 1845-57
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Publication
16567640 | J:108294
First Author: Inoue T
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Mitogen-activated protein kinase kinase 3 is a pivotal pathway regulating p38 activation in inflammatory arthritis.
Volume: 103
Issue: 14
Pages: 5484-9
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Publication
24453276 | J:211932
First Author: MacNeil AJ
Year: 2014
Journal: J Leukoc Biol
Title: Stem cell factor induces AP-1-dependent mast cell IL-6 production via MAPK kinase 3 activity.
Volume: 95
Issue: 6
Pages: 903-15
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Publication
25406311 | J:218387
First Author: Greenblatt MB
Year: 2015
Journal: J Biol Chem
Title: p38α MAPK is required for tooth morphogenesis and enamel secretion.
Volume: 290
Issue: 1
Pages: 284-95
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Publication
18283273 | J:133320
First Author: Fukuda K
Year: 2008
Journal: Lab Invest
Title: MKK3 signalling plays an essential role in leukocyte-mediated pancreatic injury in the multiple low-dose streptozotocin model.
Volume: 88
Issue: 4
Pages: 398-407
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Publication
22447969 | J:199771
First Author: Riffo-Vasquez Y
Year: 2012
Journal: Am J Respir Cell Mol Biol
Title: Mycobacterium tuberculosis chaperonin 60.1 inhibits leukocyte diapedesis in a murine model of allergic lung inflammation.
Volume: 47
Issue: 2
Pages: 245-52
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Publication
19427893 | J:152926
First Author: Sorkin LS
Year: 2009
Journal: Neuroscience
Title: MKK3, an upstream activator of p38, contributes to formalin phase 2 and late allodynia in mice.
Volume: 162
Issue: 2
Pages: 462-71
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Publication
16357362 | J:120188
First Author: Wang XM
Year: 2006
Journal: Am J Respir Cell Mol Biol
Title: Caveolin-1 confers antiinflammatory effects in murine macrophages via the MKK3/p38 MAPK pathway.
Volume: 34
Issue: 4
Pages: 434-42
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Publication
17686961 | J:145121
First Author: Ma FY
Year: 2007
Journal: Am J Physiol Renal Physiol
Title: MKK3-p38 signaling promotes apoptosis and the early inflammatory response in the obstructed mouse kidney.
Volume: 293
Issue: 5
Pages: F1556-63
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Publication
17167049 | J:118240
First Author: Seimon TA
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Combinatorial pattern recognition receptor signaling alters the balance of life and death in macrophages.
Volume: 103
Issue: 52
Pages: 19794-9
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Publication
27009039 | J:236335
First Author: Warr N
Year: 2016
Journal: Biol Reprod
Title: Genetic Analyses Reveal Functions for MAP2K3 and MAP2K6 in Mouse Testis Determination.
Volume: 94
Issue: 5
Pages: 103
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Publication
19342682 | J:147493
First Author: Cecil DL
Year: 2009
Journal: J Immunol
Title: The pattern recognition receptor CD36 is a chondrocyte hypertrophy marker associated with suppression of catabolic responses and promotion of repair responses to inflammatory stimuli.
Volume: 182
Issue: 8
Pages: 5024-31
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Publication
26119780 | J:317926
 
First Author: Srivastava A
Year: 2015
Journal: Free Radic Biol Med
Title: MKK3 deletion improves mitochondrial quality.
Volume: 87
Pages: 373-84
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Publication
23729445 | J:205361
First Author: Kang Y
Year: 2013
Journal: J Immunol
Title: MAPK kinase 3 potentiates Chlamydia HSP60-induced inflammatory response through distinct activation of NF-κB.
Volume: 191
Issue: 1
Pages: 386-94
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Publication
23275604 | J:193033
First Author: Mannam P
Year: 2013
Journal: J Immunol
Title: Endothelial MKK3 is a critical mediator of lethal murine endotoxemia and acute lung injury.
Volume: 190
Issue: 3
Pages: 1264-75
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Publication
17399693 | J:162733
First Author: Clark JE
Year: 2007
Journal: Cardiovasc Res
Title: Post-infarction remodeling is independent of mitogen-activated protein kinase kinase 3 (MKK3).
Volume: 74
Issue: 3
Pages: 466-70
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Publication
27012769 | J:234863
First Author: Schonhoff CM
Year: 2016
Journal: Am J Physiol Gastrointest Liver Physiol
Title: p38 MAPK α and β isoforms differentially regulate plasma membrane localization of MRP2.
Volume: 310
Issue: 11
Pages: G999-G1005
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Publication
23202732 | J:194180
First Author: González-Terán B
Year: 2013
Journal: J Clin Invest
Title: Eukaryotic elongation factor 2 controls TNF-α translation in LPS-induced hepatitis.
Volume: 123
Issue: 1
Pages: 164-78
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Publication
18270588 | J:132187
First Author: Dolinay T
Year: 2008
Journal: PLoS One
Title: Mitogen-activated protein kinases regulate susceptibility to ventilator-induced lung injury.
Volume: 3
Issue: 2
Pages: e1601
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Publication
18757346 | J:146100
First Author: Bulat N
Year: 2009
Journal: J Lipid Res
Title: LDLs stimulate p38 MAPKs and wound healing through SR-BI independently of Ras and PI3 kinase.
Volume: 50
Issue: 1
Pages: 81-9
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Publication
19561096 | J:151663
First Author: Yoshizawa T
Year: 2009
Journal: J Immunol
Title: Role of MAPK kinase 6 in arthritis: distinct mechanism of action in inflammation and cytokine expression.
Volume: 183
Issue: 2
Pages: 1360-7
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Publication
35971771 | J:328707
   
First Author: Romero-Becerra R
Year: 2022
Journal: Elife
Title: MKK6 deficiency promotes cardiac dysfunction through MKK3-p38γ/δ-mTOR hyperactivation.
Volume: 11
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Publication
24487387 | J:210185
First Author: Mannam P
Year: 2014
Journal: Am J Physiol Lung Cell Mol Physiol
Title: MKK3 regulates mitochondrial biogenesis and mitophagy in sepsis-induced lung injury.
Volume: 306
Issue: 7
Pages: L604-19
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Publication
24596247 | J:210829
First Author: Escolano A
Year: 2014
Journal: EMBO J
Title: Specific calcineurin targeting in macrophages confers resistance to inflammation via MKP-1 and p38.
Volume: 33
Issue: 10
Pages: 1117-33
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Publication
14657222 | J:86806
First Author: Zuckerbraun BS
Year: 2003
Journal: J Exp Med
Title: Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1.
Volume: 198
Issue: 11
Pages: 1707-16
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Publication
21368234 | J:170817
First Author: Nagaleekar VK
Year: 2011
Journal: J Immunol
Title: Translational control of NKT cell cytokine production by p38 MAPK.
Volume: 186
Issue: 7
Pages: 4140-6
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Publication
14633627 | J:86602
First Author: Otterbein LE
Year: 2003
Journal: Am J Pathol
Title: MKK3 mitogen-activated protein kinase pathway mediates carbon monoxide-induced protection against oxidant-induced lung injury.
Volume: 163
Issue: 6
Pages: 2555-63
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Genotype
Genotype
Symbol: Map2k3/Map2k3
Background: B6.129S1-Map2k3
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Map2k3/Map2k3
Background: involves: 129S1/Sv
Zygosity: hm
Has Mutant Allele: true
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HT Experiment
E-GEOD-23408 | Global gene expression profiles and the progression of pro- and anti-inflammatory pathways in mouse models
Series Id: GSE23408
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Protein Coding Gene
MGI:96629 | Jak2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:96628 | Jak1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P52332
Organism: Mus musculus/domesticus
Length: 1153  
Fragment?: false
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Protein
Q62120
Organism: Mus musculus/domesticus
Length: 1132  
Fragment?: false
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Publication
15710911 | J:96685
First Author: Chau KY
Year: 2005
Journal: Int Immunol
Title: IFN-gamma gene expression is controlled by the architectural transcription factor HMGA1.
Volume: 17
Issue: 3
Pages: 297-306
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Publication
19265160 | J:145914
First Author: Wang XM
Year: 2009
Journal: J Immunol
Title: The heme oxygenase-1/carbon monoxide pathway suppresses TLR4 signaling by regulating the interaction of TLR4 with caveolin-1.
Volume: 182
Issue: 6
Pages: 3809-18
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Publication
22351764 | J:184288
First Author: Kim SI
Year: 2012
Journal: J Biol Chem
Title: Autophagy promotes intracellular degradation of type I collagen induced by transforming growth factor (TGF)-β1.
Volume: 287
Issue: 15
Pages: 11677-88
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Publication
21610252 | J:185994
First Author: Wen HC
Year: 2011
Journal: Sci Signal
Title: p38α Signaling Induces Anoikis and Lumen Formation During Mammary Morphogenesis.
Volume: 4
Issue: 174
Pages: ra34
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Publication
21095589 | J:166998
First Author: Miller SA
Year: 2010
Journal: Mol Cell
Title: Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression.
Volume: 40
Issue: 4
Pages: 594-605
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Publication
27053161 | J:236899
 
First Author: Hosokawa H
Year: 2016
Journal: Nat Commun
Title: Akt1-mediated Gata3 phosphorylation controls the repression of IFNγ in memory-type Th2 cells.
Volume: 7
Pages: 11289
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Publication
22685317 | J:189550
First Author: Chang PP
Year: 2012
Journal: J Immunol
Title: Breakdown in repression of IFN-γ mRNA leads to accumulation of self-reactive effector CD8+ T cells.
Volume: 189
Issue: 2
Pages: 701-10
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Publication
23995235 | J:208217
First Author: Schmolka N
Year: 2013
Journal: Nat Immunol
Title: Epigenetic and transcriptional signatures of stable versus plastic differentiation of proinflammatory γδ T cell subsets.
Volume: 14
Issue: 10
Pages: 1093-1100
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Publication
31076359 | J:282502
First Author: Stone SL
Year: 2019
Journal: Immunity
Title: T-bet Transcription Factor Promotes Antibody-Secreting Cell Differentiation by Limiting the Inflammatory Effects of IFN-γ on B Cells.
Volume: 50
Issue: 5
Pages: 1172-1187.e7
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Publication
20471290 | J:160694
First Author: Mukasa R
Year: 2010
Journal: Immunity
Title: Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage.
Volume: 32
Issue: 5
Pages: 616-27
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Publication
26084024 | J:229111
First Author: Lee JH
Year: 2015
Journal: Immunity
Title: E3 Ubiquitin Ligase VHL Regulates Hypoxia-Inducible Factor-1α to Maintain Regulatory T Cell Stability and Suppressive Capacity.
Volume: 42
Issue: 6
Pages: 1062-74
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Publication
31844326 | J:290128
First Author: Hatzioannou A
Year: 2020
Journal: Nat Immunol
Title: An intrinsic role of IL-33 in Treg cell-mediated tumor immunoevasion.
Volume: 21
Issue: 1
Pages: 75-85
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Publication
32193462 | J:287402
First Author: Ren M
Year: 2020
Journal: Nat Commun
Title: Transcription factor p73 regulates Th1 differentiation.
Volume: 11
Issue: 1
Pages: 1475
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Publication
38877170 | J:353049
First Author: Janusova S
Year: 2024
Journal: EMBO Rep
Title: ABIN1 is a negative regulator of effector functions in cytotoxic T cells.
Volume: 25
Issue: 8
Pages: 3456-3485
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Publication
32445619 | J:317448
First Author: Ni J
Year: 2020
Journal: Immunity
Title: Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity.
Volume: 52
Issue: 6
Pages: 1075-1087.e8
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Publication
18684923 | J:140193
First Author: Cimmino L
Year: 2008
Journal: J Immunol
Title: Blimp-1 attenuates Th1 differentiation by repression of ifng, tbx21, and bcl6 gene expression.
Volume: 181
Issue: 4
Pages: 2338-47
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Publication
34644568 | J:324665
First Author: Zebley CC
Year: 2021
Journal: Cell Rep
Title: Proinflammatory cytokines promote TET2-mediated DNA demethylation during CD8 T cell effector differentiation.
Volume: 37
Issue: 2
Pages: 109796
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Publication
19818653 | J:153752
First Author: Feuerer M
Year: 2009
Journal: Immunity
Title: How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets.
Volume: 31
Issue: 4
Pages: 654-64
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Publication
35180231 | J:330308
First Author: Wang WL
Year: 2022
Journal: PLoS Biol
Title: microRNA-142 guards against autoimmunity by controlling Treg cell homeostasis and function.
Volume: 20
Issue: 2
Pages: e3001552
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Publication
24530058 | J:209915
First Author: Wang Y
Year: 2014
Journal: Immunity
Title: The transcription factors T-bet and Runx are required for the ontogeny of pathogenic interferon-γ-producing T helper 17 cells.
Volume: 40
Issue: 3
Pages: 355-66
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Publication
31747600 | J:287272
First Author: Castillo-Dela Cruz P
Year: 2019
Journal: Cell Rep
Title: Intestinal IL-17R Signaling Constrains IL-18-Driven Liver Inflammation by the Regulation of Microbiome-Derived Products.
Volume: 29
Issue: 8
Pages: 2270-2283.e7
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Publication
23490048 | J:259644
First Author: Li W
Year: 2013
Journal: Virology
Title: Interferon regulatory factor 7 (IRF7) is required for the optimal initial control but not subsequent clearance of lymphocytic choriomeningitis virus infection in mice.
Volume: 439
Issue: 2
Pages: 152-62
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Publication
30365177 | J:269932
First Author: Yánez DC
Year: 2019
Journal: Eur J Immunol
Title: IFITM proteins drive type 2 T helper cell differentiation and exacerbate allergic airway inflammation.
Volume: 49
Issue: 1
Pages: 66-78
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Publication
25963922 | J:224880
 
First Author: Pan W
Year: 2015
Journal: Nat Commun
Title: MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis.
Volume: 6
Pages: 7096
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Publication
2081597 | J:11088
First Author: Threadgill DW
Year: 1990
Journal: Genomics
Title: Syntenic conservation between humans and cattle. II. Human chromosome 12.
Volume: 8
Issue: 1
Pages: 29-34
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Publication
17483407 | J:123019
First Author: Levillayer F
Year: 2007
Journal: Genetics
Title: Interleukin 22 is a candidate gene for Tmevp3, a locus controlling Theiler's virus-induced neurological diseases.
Volume: 176
Issue: 3
Pages: 1835-44
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Publication
31562210 | J:280950
First Author: Gomes AC
Year: 2019
Journal: J Immunol
Title: IFN-γ-Dependent Reduction of Erythrocyte Life Span Leads to Anemia during Mycobacterial Infection.
Volume: 203
Issue: 9
Pages: 2485-2496
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Publication
38315039 | J:360545
First Author: Kagohashi K
Year: 2024
Journal: J Immunol
Title: Role of Signal-Transducing Adaptor Protein-1 for T Cell Activation and Pathogenesis of Autoimmune Demyelination and Airway Inflammation.
Volume: 212
Issue: 6
Pages: 951-961
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Protein Coding Gene
MGI:1197010 | Sumo1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P63166
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: false
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Publication
12690100 | J:211469
First Author: Zhang X
Year: 2003
Journal: J Biol Chem
Title: Carbon monoxide modulates Fas/Fas ligand, caspases, and Bcl-2 family proteins via the p38alpha mitogen-activated protein kinase pathway during ischemia-reperfusion lung injury.
Volume: 278
Issue: 24
Pages: 22061-70
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Publication
20937847 | J:165637
First Author: Yang Z
Year: 2010
Journal: J Immunol
Title: The regulation of Th1 responses by the p38 MAPK.
Volume: 185
Issue: 10
Pages: 6205-13
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Publication
28424242 | J:247857
First Author: Chornoguz O
Year: 2017
Journal: J Immunol
Title: mTORC1 Promotes T-bet Phosphorylation To Regulate Th1 Differentiation.
Volume: 198
Issue: 10
Pages: 3939-3948
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Publication
22116824 | J:180590
First Author: Alli R
Year: 2012
Journal: J Immunol
Title: A mouse model of clonal CD8+ T lymphocyte-mediated alopecia areata progressing to alopecia universalis.
Volume: 188
Issue: 1
Pages: 477-86
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Publication
19535634 | J:150115
First Author: Esensten JH
Year: 2009
Journal: J Immunol
Title: T-bet-deficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function.
Volume: 183
Issue: 1
Pages: 75-82
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Publication
29070650 | J:274965
First Author: Mittal D
Year: 2017
Journal: Cancer Immunol Res
Title: Interleukin-12 from CD103+ Batf3-Dependent Dendritic Cells Required for NK-Cell Suppression of Metastasis.
Volume: 5
Issue: 12
Pages: 1098-1108
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Publication
20237292 | J:159870
First Author: Kemp KL
Year: 2010
Journal: J Immunol
Title: Lck mediates Th2 differentiation through effects on T-bet and GATA-3.
Volume: 184
Issue: 8
Pages: 4178-84
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Publication
29524223 | J:265084
First Author: Mikami Y
Year: 2018
Journal: Eur J Immunol
Title: NCR+ ILC3 maintain larger STAT4 reservoir via T-BET to regulate type 1 features upon IL-23 stimulation in mice.
Volume: 48
Issue: 7
Pages: 1174-1180
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Publication
35720294 | J:326112
 
First Author: Xu L
Year: 2022
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