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Search results 2701 to 2800 out of 6467 for Myc

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Type Details Score
Genotype
Symbol: Mycbp2/Mycbp2 Tg(Mnx1-GFP)1Slp/?
Background: involves: C3H * C57BL/6 * DBA/2J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Mycbp2/Mycbp2
Background: involves: C57BL/6J * SSL/LeJ
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Myct1/Myct1 Tg(MMTV-PyVT)634Mul/?
Background: involves: C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Mycbp2/Mycbp2
Background: C57BL/6N-Mybpc2/Ucd
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Myct1/Myct1
Background: C57BL/6N-Myct1/MbpMmucd
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Murre C
Year: 1989
Journal: Cell
Title: A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins.
Volume: 56
Issue: 5
Pages: 777-83
Protein
Organism: Mus musculus/domesticus
Length: 2430  
Fragment?: false
Publication
First Author: Modregger J
Year: 2003
Journal: J Biol Chem
Title: Characterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1.
Volume: 278
Issue: 6
Pages: 4160-7
Publication
First Author: Stratikopoulos EE
Year: 2015
Journal: Cancer Cell
Title: Kinase and BET Inhibitors Together Clamp Inhibition of PI3K Signaling and Overcome Resistance to Therapy.
Volume: 27
Issue: 6
Pages: 837-51
Publication
First Author: Huntwork-Rodriguez S
Year: 2013
Journal: J Cell Biol
Title: JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis.
Volume: 202
Issue: 5
Pages: 747-63
Publication    
First Author: Dave K
Year: 2017
Journal: Elife
Title: Mice deficient of Myc super-enhancer region reveal differential control mechanism between normal and pathological growth.
Volume: 6
DO Term
Publication
First Author: Bloom AJ
Year: 2007
Journal: Genes Dev
Title: The requirement for Phr1 in CNS axon tract formation reveals the corticostriatal boundary as a choice point for cortical axons.
Volume: 21
Issue: 20
Pages: 2593-606
Genotype
Symbol: Mycbp2/Mycbp2 Tg(Isl1-EGFP*)1Slp/?
Background: B6.Cg-Mycbp2 Tg(Isl1-EGFP*)1Slp
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Mycbp2/Mycbp2 Tg(Nes-cre)1Kln/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mycbp2/Mycbp2 Tg(Scn10a-cre)1Rkun/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Burgess RW
Year: 2004
Journal: Mol Cell Biol
Title: Evidence for a conserved function in synapse formation reveals Phr1 as a candidate gene for respiratory failure in newborn mice.
Volume: 24
Issue: 3
Pages: 1096-105
Publication
First Author: Belver L
Year: 2019
Journal: Cancer Discov
Title: GATA3-Controlled Nucleosome Eviction Drives MYC Enhancer Activity in T-cell Development and Leukemia.
Volume: 9
Issue: 12
Pages: 1774-1791
Publication
First Author: Yang H
Year: 2002
Journal: Brain Res Dev Brain Res
Title: Developmental expression of PAM (protein associated with MYC) in the rodent brain.
Volume: 136
Issue: 1
Pages: 35-42
Publication
First Author: Lin C
Year: 2014
Journal: Genes Dev
Title: Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling.
Volume: 28
Issue: 22
Pages: 2547-63
Publication    
First Author: Dhanasekaran R
Year: 2020
Journal: Elife
Title: MYC and Twist1 cooperate to drive metastasis by eliciting crosstalk between cancer and innate immunity.
Volume: 9
Publication
First Author: Huang Z
Year: 2004
Journal: Mol Cell Biol
Title: Negative control of the Myc protein by the stress-responsive kinase Pak2.
Volume: 24
Issue: 4
Pages: 1582-94
Publication
First Author: Tsuneoka M
Year: 2006
Journal: Int J Androl
Title: Expression of Mina53, a product of a Myc target gene in mouse testis.
Volume: 29
Issue: 2
Pages: 323-30
Publication
First Author: Teye K
Year: 2004
Journal: Am J Pathol
Title: Increased expression of a Myc target gene Mina53 in human colon cancer.
Volume: 164
Issue: 1
Pages: 205-16
Publication
First Author: Choi SH
Year: 2010
Journal: Genes Dev
Title: Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells.
Volume: 24
Issue: 12
Pages: 1236-41
Publication
First Author: Bao J
Year: 1996
Journal: Oncogene
Title: Isolation and characterization of Nmi, a novel partner of Myc proteins.
Volume: 12
Issue: 10
Pages: 2171-6
Publication
First Author: Kovalchuk AL
Year: 2018
Journal: Oncotarget
Title: 3'Igh enhancers hs3b/hs4 are dispensable for Myc deregulation in mouse plasmacytomas with T(12;15) translocations.
Volume: 9
Issue: 77
Pages: 34528-34542
Genotype
Symbol: Map3k12/Map3k12 Mycbp2/Mycbp2
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Mycbp2/Mycbp2 Cntn2/Cntn2<+>
Background: involves: 129S1/Sv * A/J * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Mycbp2/Mycbp2<+>
Background: C57BL/6N-Mybpc2/Ucd
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Biran A
Year: 2021
Journal: Cancer Res
Title: Activation of Notch and Myc Signaling via B-cell-Restricted Depletion of Dnmt3a Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia.
Volume: 81
Issue: 24
Pages: 6117-6130
DO Term
Publication
First Author: Ha S
Year: 2015
Journal: Cereb Cortex
Title: A forward genetic screen in mice identifies mutants with abnormal cortical patterning.
Volume: 25
Issue: 1
Pages: 167-79
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Allele
Name: transient receptor potential cation channel, subfamily V, member 1; targeted mutation 1, Allan Basbaum
Allele Type: Targeted
Attribute String: Recombinase
Allele
Name: regulatory region 356; targeted mutation 1, Jussi Taipale
Allele Type: Targeted
Attribute String: Conditional ready, Modified regulatory region
Allele
Name: regulatory region 357; targeted mutation 1, Jussi Taipale
Allele Type: Targeted
Attribute String: Conditional ready, Modified regulatory region
Allele
Name: transgene insertion, Tom Curran
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: phospholipase D1; endonuclease-mediated mutation 1, Daniel Raben
Allele Type: Endonuclease-mediated
Attribute String: Epitope tag
Publication
First Author: Coleman AE
Year: 1999
Journal: Blood
Title: Jumping translocation breakpoint regions lead to amplification of rearranged Myc.
Volume: 93
Issue: 12
Pages: 4442-4
Publication
First Author: Semova N
Year: 2003
Journal: Genomics
Title: Molecular cloning, structural analysis, and expression of a human IRLB, MYC promoter-binding protein: new DENN domain-containing protein family emerges.
Volume: 82
Issue: 3
Pages: 343-54
Publication
First Author: Shiio Y
Year: 2006
Journal: J Biol Chem
Title: Quantitative proteomic analysis of myc-induced apoptosis: a direct role for Myc induction of the mitochondrial chloride ion channel, mtCLIC/CLIC4.
Volume: 281
Issue: 5
Pages: 2750-6
Publication
First Author: Zhu M
Year: 2011
Journal: Genome Biol
Title: Integrated miRNA and mRNA expression profiling of mouse mammary tumor models identifies miRNA signatures associated with mammary tumor lineage.
Volume: 12
Issue: 8
Pages: R77
Publication
First Author: Weisshaar B
Year: 1998
Journal: Curr Opin Plant Biol
Title: Phenylpropanoid biosynthesis and its regulation.
Volume: 1
Issue: 3
Pages: 251-7
Publication
First Author: Matus JT
Year: 2010
Journal: Plant Mol Biol
Title: Isolation of WDR and bHLH genes related to flavonoid synthesis in grapevine (Vitis vinifera L.).
Volume: 72
Issue: 6
Pages: 607-20
Protein Domain
Type: Domain
Description: This is the N-terminal region of a family of MYB and MYC transcription factors. The DNA-binding HLH domain is further downstream, . Members of the MYB and MYC family regulate the biosynthesis of phenylpropanoids in several plant species [, ].
Publication
First Author: Das B
Year: 2019
Journal: Cancer Res
Title: MYC Regulates the HIF2α Stemness Pathway via Nanog and Sox2 to Maintain Self-Renewal in Cancer Stem Cells versus Non-Stem Cancer Cells.
Volume: 79
Issue: 16
Pages: 4015-4025
Genotype
Symbol: Mnx1/Mnx1<+> Mycbp2/Mycbp2
Background: involves: 129S1/Sv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Emx1/Emx1<+> Mycbp2/Mycbp2
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ednrb/Ednrb<+> Mycbp2/Mycbp2<+>
Background: involves: 101/Rl * C3H/Rl * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Ednrb/Ednrb<+> Mycbp2/Mycbp2<+>
Background: involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Langdon WY
Year: 1986
Journal: Cell
Title: The c-myc oncogene perturbs B lymphocyte development in E-mu-myc transgenic mice.
Volume: 47
Issue: 1
Pages: 11-8
Publication
First Author: Yin L
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb alpha.
Volume: 107
Issue: 25
Pages: 11614-9
Publication
First Author: Etournay R
Year: 2005
Journal: J Cell Sci
Title: PHR1, an integral membrane protein of the inner ear sensory cells, directly interacts with myosin 1c and myosin VIIa.
Volume: 118
Issue: Pt 13
Pages: 2891-9
Publication
First Author: Edmondson DG
Year: 1990
Journal: Genes Dev
Title: A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program.
Volume: 4
Issue: 8
Pages: 1450
Publication
First Author: Mu ZM
Year: 2002
Journal: J Biol Chem
Title: Pag, a putative tumor suppressor, interacts with the Myc Box II domain of c-Myc and selectively alters its biological function and target gene expression.
Volume: 277
Issue: 45
Pages: 43175-84
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
Publication
First Author: Hoellein A
Year: 2014
Journal: Blood
Title: Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma.
Volume: 124
Issue: 13
Pages: 2081-90
Publication
First Author: Wall M
Year: 2013
Journal: Cancer Discov
Title: The mTORC1 inhibitor everolimus prevents and treats Eμ-Myc lymphoma by restoring oncogene-induced senescence.
Volume: 3
Issue: 1
Pages: 82-95
Publication
First Author: Nam J
Year: 2019
Journal: Leukemia
Title: Disruption of the Myc-PDE4B regulatory circuitry impairs B-cell lymphoma survival.
Volume: 33
Issue: 12
Pages: 2912-2923
Publication
First Author: Kelly PN
Year: 2013
Journal: Cell Death Differ
Title: Prophylactic treatment with the BH3 mimetic ABT-737 impedes Myc-driven lymphomagenesis in mice.
Volume: 20
Issue: 1
Pages: 57-63
Publication
First Author: Nakamura Y
Year: 2016
Journal: J Biol Chem
Title: Proteomic Characterization of Inhibitory Synapses Using a Novel pHluorin-tagged γ-Aminobutyric Acid Receptor, Type A (GABAA), α2 Subunit Knock-in Mouse.
Volume: 291
Issue: 23
Pages: 12394-407
Publication
First Author: Hurlin PJ
Year: 1996
Journal: EMBO J
Title: Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation.
Volume: 15
Issue: 8
Pages: 2030
Strain
Attribute String: targeted mutation, mutant strain, congenic
Publication
First Author: Wang F
Year: 2018
Journal: Cell Rep
Title: Sensory Afferents Use Different Coding Strategies for Heat and Cold.
Volume: 23
Issue: 7
Pages: 2001-2013
Publication  
First Author: Tanaka K
Year: 2023
Journal: Biochem Biophys Res Commun
Title: Repeated activation of Trpv1-positive sensory neurons facilitates tumor growth associated with changes in tumor-infiltrating immune cells.
Volume: 648
Pages: 36-43
Allele
Name: transgene insertion 1, Qinghua Wang
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: transgenic, mutant stock
Publication
First Author: Maharaj A
Year: 2012
Journal: Diabetologia
Title: Ectopic expression of glucagon receptor in skeletal muscles improves glucose homeostasis in a mouse model of diabetes.
Volume: 55
Issue: 5
Pages: 1458-68
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Annette Schurmann
Allele Type: Targeted
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 3, P Leif Bergsagel
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: regulatory region 356; targeted mutation 1.1, Jussi Taipale
Allele Type: Targeted
Attribute String: Modified regulatory region
Allele
Name: transgene insertion 13, Masashi Arai
Allele Type: Transgenic
Attribute String: Epitope tag, Inserted expressed sequence
Allele
Name: transgene insertion 6, Masashi Arai
Allele Type: Transgenic
Attribute String: Epitope tag, Inserted expressed sequence
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Allele
Name: regulatory region 478; endonuclease-mediated mutation 1, Miguel Torres
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
Allele
Name: regulatory region 477; endonuclease-mediated mutation 1, Miguel Torres
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
Publication  
First Author: Beck-Engeser GB
Year: 2008
Journal: Retrovirology
Title: Pvt1-encoded microRNAs in oncogenesis.
Volume: 5
Pages: 4
Publication
First Author: Balboni AL
Year: 2013
Journal: Cancer Res
Title: ΔNp63α-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells.
Volume: 73
Issue: 2
Pages: 1020-30
Publication
First Author: Eckberg K
Year: 2022
Journal: Am J Physiol Renal Physiol
Title: Small hairpin inhibitory RNA delivery in the metanephric organ culture identifies long noncoding RNA Pvt1 as a modulator of cyst growth.
Volume: 323
Issue: 3
Pages: F335-F348
Publication  
First Author: Vecchio E
Year: 2020
Journal: Int J Mol Sci
Title: IBTK Haploinsufficiency Affects the Tumor Microenvironment of Myc-Driven Lymphoma in E-myc Mice.
Volume: 21
Issue: 3
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Sparks AB
Year: 1996
Journal: Nat Biotechnol
Title: Cloning of ligand targets: systematic isolation of SH3 domain-containing proteins.
Volume: 14
Issue: 6
Pages: 741-4
Publication
First Author: Vecchio E
Year: 2019
Journal: Cell Death Dis
Title: IBTK contributes to B-cell lymphomagenesis in Eμ-myc transgenic mice conferring resistance to apoptosis.
Volume: 10
Issue: 4
Pages: 320
Allele
Name: transgene insertion 22, Ralph L Brinster
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: thymus specific insertion locus; transgene insertion 12A, Agnes Lavenu
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Glasgow University Veterinary Faculty
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele  
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 2, Peter J Detloff
Allele Type: Targeted
Allele  
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 3, Peter J Detloff
Allele Type: Targeted
Allele  
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 4, Peter J Detloff
Allele Type: Targeted
Allele  
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 5, Peter J Detloff
Allele Type: Targeted
Allele
Name: transgene insertion 186, Anton Berns
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele  
Name: bone morphogenetic protein 7; targeted mutation 4, Elizabeth J Robertson
Allele Type: Targeted
Allele
Name: transgene insertion 1, Weiguo Zhang
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: odd-skipped related 2; targeted mutation 3, Rulang Jiang
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Null/knockout
Allele
Name: transgene insertion 2, Gregory J Hannon
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 2, Gregory J Hannon
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Daisuke Ito
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: collagen, type I, alpha 1; targeted mutation 1, TC Dale
Allele Type: Targeted
Attribute String: Inducible, Inserted expressed sequence