| Type |
Details |
Score |
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal day 5 |
| Stage: |
28 |
| Structure . Name: |
cerebral cortex |
| Notes: |
FACS sorted SST expressing neurons |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| CL Term |
|
•
•
•
•
•
|
| CL Term |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
embryonic day 16.5 |
| Stage: |
24 |
| Structure . Name: |
cerebral cortex |
| Notes: |
FACs sorted SST reporter + neurons |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal day 1 |
| Stage: |
27 |
| Structure . Name: |
cerebral cortex |
| Notes: |
FACs sorted SST reporter + neurons |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal day 5 |
| Stage: |
28 |
| Structure . Name: |
cerebral cortex |
| Notes: |
FACs sorted SST reporter + neurons |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7520930 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-08-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716821 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:7521967 |
| Age: |
embryonic day 13.5 |
| Image: |
4I Brn3a |
| Note: |
Expression co-localized with Sst in subset of ganglion cells. |
| Specimen Label: |
4I Brn3a |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6403149 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-11-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3279026 |
| Pattern: |
Regionally restricted |
| Stage: |
TS26 |
| Assay Id: |
MGI:7562099 |
| Age: |
embryonic day 18.5 |
| Image: |
S1A |
| Note: |
Co-expressed with Sst in a subset of neurons within the pre-botzinger complex. |
| Specimen Label: |
S1A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6403149 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-04-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1755026 |
| Pattern: |
Regionally restricted |
| Stage: |
TS26 |
| Assay Id: |
MGI:6403157 |
| Age: |
embryonic day 18.5 |
| Image: |
4A Jmjd3+/+ |
| Note: |
Expression was detected in neurons defining the pre-Botzinger complex. Coexpression with Sst was detected in a subset of neurons. |
| Specimen Label: |
4A Jmjd3+/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6403149 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-04-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3279026 |
| Pattern: |
Regionally restricted |
| Stage: |
TS26 |
| Assay Id: |
MGI:6403157 |
| Age: |
embryonic day 18.5 |
| Image: |
4A Jmjd3+/+ |
| Note: |
Expression was detected in neurons defining the pre-Botzinger complex. Coexpression with Sst was detected in a subset of neurons. |
| Specimen Label: |
4A Jmjd3+/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
Baseline |
| Source: |
GEO |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal month 9 |
| Stage: |
28 |
| Structure . Name: |
telencephalon |
| Notes: |
somatostatin-expressing neuron; the authors did not identify the Sst allele used; this is the most likely one |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal month 9 |
| Stage: |
28 |
| Structure . Name: |
telencephalon |
| Notes: |
somatostatin-expressing neuron; the authors did not identify the Sst allele used; this is the most likely one |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal month 9 |
| Stage: |
28 |
| Structure . Name: |
telencephalon |
| Notes: |
somatostatin-expressing neuron; the authors did not identify the Sst allele used; this is the most likely one |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal month 9 |
| Stage: |
28 |
| Structure . Name: |
telencephalon |
| Notes: |
somatostatin-expressing neuron; the authors did not identify the Sst allele used; this is the most likely one |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal month 9 |
| Stage: |
28 |
| Structure . Name: |
telencephalon |
| Notes: |
somatostatin-expressing neuron; the authors did not identify the Sst allele used; this is the most likely one |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal month 9 |
| Stage: |
28 |
| Structure . Name: |
telencephalon |
| Notes: |
somatostatin-expressing neuron; the authors did not identify the Sst allele used; this is the most likely one |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal month 9 |
| Stage: |
28 |
| Structure . Name: |
telencephalon |
| Notes: |
somatostatin-expressing neuron; the authors did not identify the Sst allele used; this is the most likely one |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal month 9 |
| Stage: |
28 |
| Structure . Name: |
telencephalon |
| Notes: |
somatostatin-expressing neuron; the authors did not identify the Sst allele used; this is the most likely one |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal month 9 |
| Stage: |
28 |
| Structure . Name: |
telencephalon |
| Notes: |
somatostatin-expressing neuron; the authors did not identify the Sst allele used; this is the most likely one |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal month 9 |
| Stage: |
28 |
| Structure . Name: |
telencephalon |
| Notes: |
somatostatin-expressing neuron; the authors did not identify the Sst allele used; this is the most likely one |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal month 9 |
| Stage: |
28 |
| Structure . Name: |
telencephalon |
| Notes: |
somatostatin-expressing neuron; the authors did not identify the Sst allele used; this is the most likely one |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal month 9 |
| Stage: |
28 |
| Structure . Name: |
telencephalon |
| Notes: |
somatostatin-expressing neuron; the authors did not identify the Sst allele used; this is the most likely one |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal month 9 |
| Stage: |
28 |
| Structure . Name: |
telencephalon |
| Notes: |
somatostatin-expressing neuron; the authors did not identify the Sst allele used; this is the most likely one |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal month 9 |
| Stage: |
28 |
| Structure . Name: |
telencephalon |
| Notes: |
somatostatin-expressing neuron; the authors did not identify the Sst allele used; this is the most likely one |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal month 9 |
| Stage: |
28 |
| Structure . Name: |
telencephalon |
| Notes: |
somatostatin-expressing neuron; the authors did not identify the Sst allele used; this is the most likely one |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| HT Sample |
| Organism Name: |
mouse, laboratory |
| Sex: |
Not Specified |
| Age: |
postnatal month 9 |
| Stage: |
28 |
| Structure . Name: |
telencephalon |
| Notes: |
somatostatin-expressing neuron; the authors did not identify the Sst allele used; this is the most likely one |
| Curation Status: |
Curated |
|
•
•
•
•
•
|
| Allele |
| Name: |
somatostatin; endonuclease-mediated mutation 1, Biocytogen LLC |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Recombinase |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6403150 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-04-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1755026 |
| Pattern: |
Regionally restricted |
| Stage: |
TS26 |
| Assay Id: |
MGI:6403161 |
| Age: |
embryonic day 18.5 |
| Image: |
4C Jmjd3+/+ |
| Note: |
Expression was detected in a subset of pre-Botzinger complex neurons in the ventrolateral medulla. Co-expression with Sst was detected in a subset of neurons. |
| Specimen Label: |
4C Jmjd3+/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6403150 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-04-07 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3279026 |
| Pattern: |
Regionally restricted |
| Stage: |
TS26 |
| Assay Id: |
MGI:6403161 |
| Age: |
embryonic day 18.5 |
| Image: |
4C Jmjd3+/+ |
| Note: |
Expression was detected in a subset of pre-Botzinger complex neurons in the ventrolateral medulla. Co-expression with Sst was detected in a subset of neurons. |
| Specimen Label: |
4C Jmjd3+/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Sst/Sst<+> |
| Background: |
Not Specified |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7505577 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-07-10 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3644628 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:7505628 |
| Age: |
postnatal day 25 |
| Image: |
S5A/D |
| Note: |
Expression was detected in interneurons in the P25 visual cortex. Some immunopositive cells were also labeled with Sst and/or Nr2f2. Single positive cells were also observed in the deep layers. |
| Specimen Label: |
S5A/D |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5792330 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-07-10 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3644628 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:7505588 |
| Age: |
postnatal day 25 |
| Image: |
S5A/B |
| Note: |
Expression was detected in interneurons in the P25 visual cortex. Some immunopositive cells were also labeled with Sst and/or Calb2. Single positive cells were observed in the deep layers. |
| Specimen Label: |
S5A/B |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
This presumed domain is functionally uncharacterised. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 80 amino acids in length. There is a conserved SST sequence motif.This domain can be found in telomerase protein component 1 (TEP1), which is a component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini []. |
|
•
•
•
•
•
|
| CL Term |
|
•
•
•
•
•
|
| Allele |
| Name: |
somatostatin; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Recombinase |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
489
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Venteicher AS |
| Year: |
2009 |
| Journal: |
Science |
| Title: |
A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis. |
| Volume: |
323 |
| Issue: |
5914 |
| Pages: |
644-8 |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
Baseline |
| Source: |
GEO |
|
•
•
•
•
•
|
| Allele |
| Name: |
somatostatin; targeted mutation 1.1, Hitoshi Okamura |
| Allele Type: |
Targeted |
| Attribute String: |
Inserted expressed sequence, Null/knockout, Reporter |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
E-GEOD-67403 |
| Experiment Type: |
RNA-Seq |
| Study Type: |
Baseline |
| Source: |
GEO |
|
•
•
•
•
•
|
| Allele |
| Name: |
somatostatin; targeted mutation 1, Z Josh Huang |
| Allele Type: |
Targeted |
| Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
| Allele |
| Name: |
somatostatin; targeted mutation 2.1, Z Josh Huang |
| Allele Type: |
Targeted |
| Attribute String: |
Knockdown, Recombinase |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Calbet M |
| Year: |
1999 |
| Journal: |
Brain Res Mol Brain Res |
| Title: |
Cortistatin and somatostatin mRNAs are differentially regulated in response to kainate. |
| Volume: |
72 |
| Issue: |
1 |
| Pages: |
55-64 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McKenzie MG |
| Year: |
2019 |
| Journal: |
Neuron |
| Title: |
Non-canonical Wnt Signaling through Ryk Regulates the Generation of Somatostatin- and Parvalbumin-Expressing Cortical Interneurons. |
| Volume: |
103 |
| Issue: |
5 |
| Pages: |
853-864.e4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kreienkamp HJ |
| Year: |
1999 |
| Journal: |
FEBS Lett |
| Title: |
Somatostatin receptor subtype 1 modulates basal inhibition of growth hormone release in somatotrophs. |
| Volume: |
462 |
| Issue: |
3 |
| Pages: |
464-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Deng M |
| Year: |
2020 |
| Journal: |
Aging Cell |
| Title: |
Mossy cell synaptic dysfunction causes memory imprecision via miR-128 inhibition of STIM2 in Alzheimer's disease mouse model. |
| Volume: |
19 |
| Issue: |
5 |
| Pages: |
e13144 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jang HJ |
| Year: |
2020 |
| Journal: |
Sci Adv |
| Title: |
Distinct roles of parvalbumin and somatostatin interneurons in gating the synchronization of spike times in the neocortex. |
| Volume: |
6 |
| Issue: |
17 |
| Pages: |
eaay5333 |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
targeted mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
targeted mutation, mutant strain, congenic |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, targeted mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Sst/Sst<+> |
| Background: |
involves: C57BL/6 * SJL |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Sst/Sst |
| Background: |
involves: 129S4/SvJae * C57BL/6 * SJL |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zühlke C |
| Year: |
1989 |
| Journal: |
Genet Res |
| Title: |
cDNA sequence and chromosomal localization of the mouse parvalbumin gene, Pva. |
| Volume: |
54 |
| Issue: |
1 |
| Pages: |
37-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shirozu M |
| Year: |
1996 |
| Journal: |
Genomics |
| Title: |
Characterization of novel secreted and membrane proteins isolated by the signal sequence trap method. |
| Volume: |
37 |
| Issue: |
3 |
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2021 |
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Type I interferon mediated induction of somatostatin leads to suppression of ghrelin and appetite thereby promoting viral immunity in mice. |
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tgaa089 |
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J Comp Neurol |
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•
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•
•
|
| Genotype |
| Symbol: |
Mecp2/? Sst/Sst<+> |
| Background: |
involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ptchd1/? Sst/Sst<+> |
| Background: |
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eef1a1/Eef1a1 Sst/Sst<+> |
| Background: |
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|