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Search results 2801 to 2900 out of 4701 for Bcl2

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Type Details Score
Publication
First Author: Seo SY
Year: 2004
Journal: J Biol Chem
Title: BAD is a pro-survival factor prior to activation of its pro-apoptotic function.
Volume: 279
Issue: 40
Pages: 42240-9
Publication
First Author: Carrigan SO
Year: 2010
Journal: J Immunol
Title: IFN regulatory factor 3 contributes to the host response during Pseudomonas aeruginosa lung infection in mice.
Volume: 185
Issue: 6
Pages: 3602-9
Publication
First Author: Haftmann C
Year: 2015
Journal: Eur J Immunol
Title: miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim.
Volume: 45
Issue: 4
Pages: 1192-205
Publication
First Author: Negishi H
Year: 2012
Journal: Nat Immunol
Title: Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses.
Volume: 13
Issue: 7
Pages: 659-66
Publication
First Author: Couzinet A
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: A cell-type-specific requirement for IFN regulatory factor 5 (IRF5) in Fas-induced apoptosis.
Volume: 105
Issue: 7
Pages: 2556-61
Publication
First Author: Warzée B
Year: 2010
Journal: Mol Immunol
Title: Viral induction of Zac1b through TLR3- and IRF3-dependent pathways.
Volume: 48
Issue: 1-3
Pages: 119-27
Publication
First Author: Chen HW
Year: 2013
Journal: J Immunol
Title: The roles of IRF-3 and IRF-7 in innate antiviral immunity against dengue virus.
Volume: 191
Issue: 8
Pages: 4194-201
Publication
First Author: Spann KM
Year: 2014
Journal: Am J Pathol
Title: IRF-3, IRF-7, and IPS-1 promote host defense against acute human metapneumovirus infection in neonatal mice.
Volume: 184
Issue: 6
Pages: 1795-806
Publication
First Author: Prantner D
Year: 2011
Journal: Infect Immun
Title: Interferon regulatory transcription factor 3 protects mice from uterine horn pathology during Chlamydia muridarum genital infection.
Volume: 79
Issue: 10
Pages: 3922-33
Publication
First Author: Xu P
Year: 2014
Journal: Mol Cell
Title: Innate antiviral host defense attenuates TGF-β function through IRF3-mediated suppression of Smad signaling.
Volume: 56
Issue: 6
Pages: 723-37
Publication  
First Author: Wang E
Year: 2015
Journal: Elife
Title: The transcriptional cofactor TRIM33 prevents apoptosis in B lymphoblastic leukemia by deactivating a single enhancer.
Volume: 4
Pages: e06377
Publication
First Author: Cai Z
Year: 2020
Journal: Cell Rep
Title: Targeting Bim via a lncRNA Morrbid Regulates the Survival of Preleukemic and Leukemic Cells.
Volume: 31
Issue: 12
Pages: 107816
Publication
First Author: Valverde-Lopez JA
Year: 2024
Journal: PLoS Genet
Title: P53 and BCL-2 family proteins PUMA and NOXA define competitive fitness in pluripotent cell competition.
Volume: 20
Issue: 3
Pages: e1011193
Publication
First Author: Hinds MG
Year: 2007
Journal: Cell Death Differ
Title: Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets.
Volume: 14
Issue: 1
Pages: 128-36
Publication
First Author: Li J
Year: 2006
Journal: J Biol Chem
Title: Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53.
Volume: 281
Issue: 11
Pages: 7260-70
Publication
First Author: Watanabe J
Year: 2013
Journal: FEBS J
Title: Ubiquitin-like protein MNSFβ covalently binds to Bcl-G and enhances lipopolysaccharide/interferon γ-induced apoptosis in macrophages.
Volume: 280
Issue: 5
Pages: 1281-93
Publication
First Author: Zhang W
Year: 2008
Journal: J Biol Chem
Title: RACK1 and CIS mediate the degradation of BimEL in cancer cells.
Volume: 283
Issue: 24
Pages: 16416-26
Publication
First Author: Puthalakath H
Year: 1999
Journal: Mol Cell
Title: The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex.
Volume: 3
Issue: 3
Pages: 287-96
Publication
First Author: Kuribara R
Year: 2004
Journal: Mol Cell Biol
Title: Roles of Bim in apoptosis of normal and Bcr-Abl-expressing hematopoietic progenitors.
Volume: 24
Issue: 14
Pages: 6172-83
Publication
First Author: Andrews SF
Year: 2009
Journal: J Immunol
Title: Transitional B cells exhibit a B cell receptor-specific nuclear defect in gene transcription.
Volume: 182
Issue: 5
Pages: 2868-78
Publication
First Author: O'Reilly LA
Year: 2009
Journal: J Immunol
Title: MEK/ERK-mediated phosphorylation of Bim is required to ensure survival of T and B lymphocytes during mitogenic stimulation.
Volume: 183
Issue: 1
Pages: 261-9
Publication
First Author: Dai H
Year: 2011
Journal: J Cell Biol
Title: Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization.
Volume: 194
Issue: 1
Pages: 39-48
Publication
First Author: Rodriguez DA
Year: 2012
Journal: EMBO J
Title: BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α.
Volume: 31
Issue: 10
Pages: 2322-35
Publication
First Author: Li Y
Year: 2016
Journal: Oncotarget
Title: BIM mediates oncogene inactivation-induced apoptosis in multiple transgenic mouse models of acute lymphoblastic leukemia.
Volume: 7
Issue: 19
Pages: 26926-34
Publication
First Author: Knudson CM
Year: 1995
Journal: Science
Title: Bax-deficient mice with lymphoid hyperplasia and male germ cell death.
Volume: 270
Issue: 5233
Pages: 96-9
Publication
First Author: Jones-Mason ME
Year: 2012
Journal: Immunity
Title: E protein transcription factors are required for the development of CD4(+) lineage T cells.
Volume: 36
Issue: 3
Pages: 348-61
Publication
First Author: Hepworth MR
Year: 2015
Journal: Science
Title: Immune tolerance. Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4⁺ T cells.
Volume: 348
Issue: 6238
Pages: 1031-5
Allele
Name: DNA methyltransferase 1; targeted mutation 1, Stanley J Korsmeyer
Allele Type: Targeted
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, H Christian Reinhardt
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
Allele
Name: B cell leukemia/lymphoma 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Publication
First Author: Rathinam VA
Year: 2010
Journal: Nat Immunol
Title: The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.
Volume: 11
Issue: 5
Pages: 395-402
Publication
First Author: Molle C
Year: 2007
Journal: J Immunol
Title: IL-27 synthesis induced by TLR ligation critically depends on IFN regulatory factor 3.
Volume: 178
Issue: 12
Pages: 7607-15
Publication
First Author: Sharma S
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Suppression of systemic autoimmunity by the innate immune adaptor STING.
Volume: 112
Issue: 7
Pages: E710-7
Publication
First Author: Porta C
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB.
Volume: 106
Issue: 35
Pages: 14978-83
Publication
First Author: Zhao R
Year: 2007
Journal: PLoS Biol
Title: DNA damage-induced Bcl-xL deamidation is mediated by NHE-1 antiport regulated intracellular pH.
Volume: 5
Issue: 1
Pages: e1
Publication
First Author: Wang Z
Year: 2008
Journal: J Biol Chem
Title: Constitutive production of NF-kappaB2 p52 is not tumorigenic but predisposes mice to inflammatory autoimmune disease by repressing Bim expression.
Volume: 283
Issue: 16
Pages: 10698-706
Publication
First Author: Min-Oo G
Year: 2014
Journal: J Exp Med
Title: Proapoptotic Bim regulates antigen-specific NK cell contraction and the generation of the memory NK cell pool after cytomegalovirus infection.
Volume: 211
Issue: 7
Pages: 1289-96
Publication
First Author: Trumstedt C
Year: 2007
Journal: J Leukoc Biol
Title: Role of IRAK4 and IRF3 in the control of intracellular infection with Chlamydia pneumoniae.
Volume: 81
Issue: 6
Pages: 1591-8
Publication
First Author: O'Connell RM
Year: 2004
Journal: J Exp Med
Title: Type I interferon production enhances susceptibility to Listeria monocytogenes infection.
Volume: 200
Issue: 4
Pages: 437-45
Publication
First Author: Schuessler A
Year: 2012
Journal: J Virol
Title: West Nile virus noncoding subgenomic RNA contributes to viral evasion of the type I interferon-mediated antiviral response.
Volume: 86
Issue: 10
Pages: 5708-18
Publication
First Author: Negishi H
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Essential contribution of IRF3 to intestinal homeostasis and microbiota-mediated Tslp gene induction.
Volume: 109
Issue: 51
Pages: 21016-21
Publication
First Author: Carpentier PA
Year: 2007
Journal: Glia
Title: Distinct roles of protein kinase R and toll-like receptor 3 in the activation of astrocytes by viral stimuli.
Volume: 55
Issue: 3
Pages: 239-52
Publication
First Author: Jakobsen MR
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication.
Volume: 110
Issue: 48
Pages: E4571-80
Publication
First Author: Mavrakis KJ
Year: 2011
Journal: Nat Genet
Title: A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL).
Volume: 43
Issue: 7
Pages: 673-8
Publication
First Author: Liu YP
Year: 2012
Journal: J Immunol
Title: Endoplasmic reticulum stress regulates the innate immunity critical transcription factor IRF3.
Volume: 189
Issue: 9
Pages: 4630-9
Publication
First Author: Lee H
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Zinc-finger antiviral protein mediates retinoic acid inducible gene I-like receptor-independent antiviral response to murine leukemia virus.
Volume: 110
Issue: 30
Pages: 12379-84
Publication
First Author: Ruscher R
Year: 2017
Journal: Nat Immunol
Title: CD8αα intraepithelial lymphocytes arise from two main thymic precursors.
Volume: 18
Issue: 7
Pages: 771-779
Publication
First Author: Tan J
Year: 2002
Journal: Mech Dev
Title: Evidence for coordinated interaction of cyclin D3 with p21 and cdk6 in directing the development of uterine stromal cell decidualization and polyploidy during implantation.
Volume: 111
Issue: 1-2
Pages: 99-113
Publication
First Author: Qi XJ
Year: 2006
Journal: J Biol Chem
Title: Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function.
Volume: 281
Issue: 2
Pages: 813-23
Publication
First Author: Yamaguchi R
Year: 2008
Journal: Mol Cell
Title: Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization.
Volume: 31
Issue: 4
Pages: 557-69
Publication
First Author: Klee M
Year: 2009
Journal: EMBO J
Title: Mitochondrial apoptosis induced by BH3-only molecules in the exclusive presence of endoplasmic reticular Bak.
Volume: 28
Issue: 12
Pages: 1757-68
Publication
First Author: Kim H
Year: 2009
Journal: Mol Cell
Title: Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.
Volume: 36
Issue: 3
Pages: 487-99
Publication
First Author: Jabbour AM
Year: 2010
Journal: Blood
Title: Myeloid progenitor cells lacking p53 exhibit delayed up-regulation of Puma and prolonged survival after cytokine deprivation.
Volume: 115
Issue: 2
Pages: 344-52
Publication
First Author: Sandow JJ
Year: 2012
Journal: Cell Death Differ
Title: Cytokine receptor signaling activates an IKK-dependent phosphorylation of PUMA to prevent cell death.
Volume: 19
Issue: 4
Pages: 633-41
Publication
First Author: Cabon L
Year: 2012
Journal: Cell Death Differ
Title: BID regulates AIF-mediated caspase-independent necroptosis by promoting BAX activation.
Volume: 19
Issue: 2
Pages: 245-56
Publication
First Author: Bin G
Year: 2016
Journal: Exp Cell Res
Title: Fluid shear stress suppresses TNF-α-induced apoptosis in MC3T3-E1 cells: Involvement of ERK5-AKT-FoxO3a-Bim/FasL signaling pathways.
Volume: 343
Issue: 2
Pages: 208-217
Publication
First Author: Kodama T
Year: 2013
Journal: J Biol Chem
Title: The Bcl-2 homology domain 3 (BH3)-only proteins Bim and bid are functionally active and restrained by anti-apoptotic Bcl-2 family proteins in healthy liver.
Volume: 288
Issue: 42
Pages: 30009-18
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: mutant strain, endonuclease-mediated mutation, coisogenic
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Genotype
Symbol: Bcl2/Bcl2 Bcl2l11/Bcl2l11<+>
Background: B6.129-Bcl2 Bcl2l11
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bbc3/Bbc3 Bnip3l/Bnip3l
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bcl2/Bcl2 Bcl2l11/Bcl2l11
Background: B6.Cg-Bcl2 Bcl2l11/Bcl2l11
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bcl2/Bcl2 Bcl2l11/Bcl2l11<+>
Background: B6.Cg-Bcl2 Bcl2l11
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bcl2l11/Bcl2l11<+> Bmf/Bmf<+>
Background: B6.129S-Bcl2l11 Bmf
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bbc3/Bbc3 Trp53/Trp53
Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bcl2l11/Bcl2l11 Mirc14/Mirc14
Background: involves: 129S1/Sv * C57BL/6 * C57BL/6N * FVB/N * SJL
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bcl2l11/Bcl2l11 Foxp3/Foxp3<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Apc/Apc<+> Bcl2l14/Bcl2l14
Background: involves: C57BL/6 * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hrk/Hrk<+>
Background: C57BL/6-Hrk
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Bbc3/Bbc3 Ctcf/Ctcf Tg(Nes-cre)2472Pick/?
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bcl2l11/Bcl2l11 Hrk/Hrk
Background: involves: 129S1/Sv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bcl2l1/Bcl2l1 Hrk/Hrk
Background: involves: C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bcl2l11/Bcl2l11<+> Trp53/Trp53
Background: B6.129-Bcl2l11 Trp53
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Meinen S
Year: 2011
Journal: EMBO Mol Med
Title: Apoptosis inhibitors and mini-agrin have additive benefits in congenital muscular dystrophy mice.
Volume: 3
Issue: 8
Pages: 465-79
Publication
First Author: Ray AT
Year: 2020
Journal: Genes Dev
Title: FGF signaling regulates development by processes beyond canonical pathways.
Volume: 34
Issue: 23-24
Pages: 1735-1752
Publication
First Author: Mosinger Ogilvie J
Year: 1998
Journal: Invest Ophthalmol Vis Sci
Title: Suppression of developmental retinal cell death but not of photoreceptor degeneration in Bax-deficient mice.
Volume: 39
Issue: 9
Pages: 1713-20
Publication
First Author: Majumder PK
Year: 2004
Journal: Nat Med
Title: mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.
Volume: 10
Issue: 6
Pages: 594-601
Publication
First Author: Dempsey CE
Year: 2005
Journal: FEBS Lett
Title: Expression of pro-apoptotic Bfk isoforms reduces during malignant transformation in the human gastrointestinal tract.
Volume: 579
Issue: 17
Pages: 3646-50
Protein Domain
Type: Family
Description: Bcl-2-like protein 15, also known as Bfk, is a member of the bcl2 gene family. It is highly expressed in the epididymis in mouse []and in tissues of the gastrointestinal tract, where it may help to protect against the development of gastrointestinal malignancy [].
Protein Domain
Type: Conserved_site
Description: Bax inhibitor-1 (BI-1) (gene TEGT) []is a suppressor of apoptosis that interacts with BCL2 and BCL-X. These are proteins of about 25kDa which seem to contain seven transmembrane domains. Homologues are found in plants and bacteria.This entry corresponds to a conserved region that starts with the beginning of the third transmembrane domain and endsin the middle of the fourth one.
Publication
First Author: Pena JC
Year: 1999
Journal: EMBO J
Title: Manipulation of outer root sheath cell survival perturbs the hair-growth cycle.
Volume: 18
Issue: 13
Pages: 3596-603
Publication
First Author: Müller-Röver S
Year: 2000
Journal: Am J Pathol
Title: Overexpression of Bcl-2 protects from ultraviolet B-induced apoptosis but promotes hair follicle regression and chemotherapy-induced alopecia.
Volume: 156
Issue: 4
Pages: 1395-405
Strain
Attribute String: coisogenic, mutant strain, transgenic
Publication
First Author: Pellegrini M
Year: 2005
Journal: Blood
Title: FADD and caspase-8 are required for cytokine-induced proliferation of hemopoietic progenitor cells.
Volume: 106
Issue: 5
Pages: 1581-9
Publication
First Author: Forristal CE
Year: 2015
Journal: Leukemia
Title: Hypoxia inducible factor (HIF)-2α accelerates disease progression in mouse models of leukemia and lymphoma but is not a poor prognosis factor in human AML.
Volume: 29
Issue: 10
Pages: 2075-85
Publication
First Author: Kozuma Y
Year: 2009
Journal: Leukemia
Title: Caspase activation is involved in early megakaryocyte differentiation but not in platelet production from megakaryocytes.
Volume: 23
Issue: 6
Pages: 1080-6
Publication
First Author: Boice M
Year: 2016
Journal: Cell
Title: Loss of the HVEM Tumor Suppressor in Lymphoma and Restoration by Modified CAR-T Cells.
Volume: 167
Issue: 2
Pages: 405-418.e13
Allele
Name: transgene insertion 1, Eric Lagasse
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion A, Yassemi Capetanaki
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion B, Yassemi Capetanaki
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: mutant strain, transgenic
Publication
First Author: Del Real MM
Year: 2013
Journal: Development
Title: Architecture of a lymphomyeloid developmental switch controlled by PU.1, Notch and Gata3.
Volume: 140
Issue: 6
Pages: 1207-19
Publication
First Author: Kumar L
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: A 10-aa-long sequence in SLP-76 upstream of the Gads binding site is essential for T cell development and function.
Volume: 102
Issue: 52
Pages: 19063-8
Publication
First Author: Taghon T
Year: 2007
Journal: Nat Immunol
Title: Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3.
Volume: 8
Issue: 8
Pages: 845-55
Publication
First Author: Yui MA
Year: 2010
Journal: J Immunol
Title: Fine-scale staging of T cell lineage commitment in adult mouse thymus.
Volume: 185
Issue: 1
Pages: 284-93
Strain
Attribute String: mutant strain, transgenic
Publication
First Author: Fisher IB
Year: 2012
Journal: J Biol Chem
Title: Role for Ets-2(Thr-72) transcription factor in stage-specific thymocyte development and survival.
Volume: 287
Issue: 8
Pages: 5199-210
Publication
First Author: Owens BM
Year: 2006
Journal: Br J Haematol
Title: TLX1/HOX11-mediated disruption of primary thymocyte differentiation prior to the CD4+CD8+ double-positive stage.
Volume: 132
Issue: 2
Pages: 216-29
Strain
Attribute String: congenic, mutant strain, transgenic