| Type |
Details |
Score |
| Publication |
| First Author: |
Fang J |
| Year: |
2018 |
| Journal: |
Cell Rep |
| Title: |
TRAF6 Mediates Basal Activation of NF-κB Necessary for Hematopoietic Stem Cell Homeostasis. |
| Volume: |
22 |
| Issue: |
5 |
| Pages: |
1250-1262 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kanazawa K |
| Year: |
2005 |
| Journal: |
J Bone Miner Res |
| Title: |
TRAF2 is essential for TNF-alpha-induced osteoclastogenesis. |
| Volume: |
20 |
| Issue: |
5 |
| Pages: |
840-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Blonska M |
| Year: |
2013 |
| Journal: |
Sci Signal |
| Title: |
Activation of the transcription factor c-Maf in T cells is dependent on the CARMA1-IKKβ signaling cascade. |
| Volume: |
6 |
| Issue: |
306 |
| Pages: |
ra110 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li L |
| Year: |
2009 |
| Journal: |
Biochim Biophys Acta |
| Title: |
The zinc finger protein A20 targets TRAF2 to the lysosomes for degradation. |
| Volume: |
1793 |
| Issue: |
2 |
| Pages: |
346-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chavdoula E |
| Year: |
2019 |
| Journal: |
Life Sci Alliance |
| Title: |
CHUK/IKK-α loss in lung epithelial cells enhances NSCLC growth associated with HIF up-regulation. |
| Volume: |
2 |
| Issue: |
6 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zuo Y |
| Year: |
2020 |
| Journal: |
Nat Commun |
| Title: |
Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
1146 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kupka S |
| Year: |
2016 |
| Journal: |
Cell Rep |
| Title: |
SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes. |
| Volume: |
16 |
| Issue: |
9 |
| Pages: |
2271-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gravestein LA |
| Year: |
1998 |
| Journal: |
Eur J Immunol |
| Title: |
The TNF receptor family member CD27 signals to Jun N-terminal kinase via Traf-2. |
| Volume: |
28 |
| Issue: |
7 |
| Pages: |
2208-16 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nishitoh H |
| Year: |
2002 |
| Journal: |
Genes Dev |
| Title: |
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. |
| Volume: |
16 |
| Issue: |
11 |
| Pages: |
1345-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sizemore N |
| Year: |
2004 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Inhibitor of kappaB kinase is required to activate a subset of interferon gamma-stimulated genes. |
| Volume: |
101 |
| Issue: |
21 |
| Pages: |
7994-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lamkanfi M |
| Year: |
2005 |
| Journal: |
J Biol Chem |
| Title: |
A novel caspase-2 complex containing TRAF2 and RIP1. |
| Volume: |
280 |
| Issue: |
8 |
| Pages: |
6923-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kumar A |
| Year: |
2001 |
| Journal: |
J Biol Chem |
| Title: |
The ectodermal dysplasia receptor activates the nuclear factor-kappaB, JNK, and cell death pathways and binds to ectodysplasin A. |
| Volume: |
276 |
| Issue: |
4 |
| Pages: |
2668-77 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yeramian A |
| Year: |
2011 |
| Journal: |
Lab Invest |
| Title: |
Nuclear factor-κB2/p100 promotes endometrial carcinoma cell survival under hypoxia in a HIF-1α independent manner. |
| Volume: |
91 |
| Issue: |
6 |
| Pages: |
859-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fujita H |
| Year: |
2018 |
| Journal: |
Cell Rep |
| Title: |
Cooperative Domain Formation by Homologous Motifs in HOIL-1L and SHARPIN Plays A Crucial Role in LUBAC Stabilization. |
| Volume: |
23 |
| Issue: |
4 |
| Pages: |
1192-1204 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Elbaz M |
| Year: |
2015 |
| Journal: |
Cell Death Dis |
| Title: |
Life or death by NFκB, Losartan promotes survival in dy2J/dy2J mouse of MDC1A. |
| Volume: |
6 |
|
| Pages: |
e1690 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1210
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
309
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
291
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
198
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
241
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
410
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
309
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
260
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
292
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
329
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
224
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1210
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
291
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
309
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1209
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
228
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1209
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
242
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1354
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
408
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
291
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
240
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
198
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thomas Y |
| Year: |
2018 |
| Journal: |
PLoS One |
| Title: |
The NEDD8 E3 ligase DCNL5 is phosphorylated by IKK alpha during Toll-like receptor activation. |
| Volume: |
13 |
| Issue: |
6 |
| Pages: |
e0199197 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tanaka M |
| Year: |
1999 |
| Journal: |
Immunity |
| Title: |
Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice. |
| Volume: |
10 |
| Issue: |
4 |
| Pages: |
421-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hu MC |
| Year: |
1999 |
| Journal: |
Oncogene |
| Title: |
Hematopoietic progenitor kinase-1 (HPK1) stress response signaling pathway activates IkappaB kinases (IKK-alpha/beta) and IKK-beta is a developmentally regulated protein kinase. |
| Volume: |
18 |
| Issue: |
40 |
| Pages: |
5514-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wong JC |
| Year: |
2000 |
| Journal: |
Genomics |
| Title: |
Cloning and analysis of the mouse Fanconi anemia group A cDNA and an overlapping penta zinc finger cDNA. |
| Volume: |
67 |
| Issue: |
3 |
| Pages: |
273-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jang W |
| Year: |
1997 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Mouse p150Glued (dynactin 1) cDNA sequence and evaluation as a candidate for the neuromuscular disease mutation mnd2. |
| Volume: |
231 |
| Issue: |
2 |
| Pages: |
344-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xiong H |
| Year: |
2004 |
| Journal: |
J Biol Chem |
| Title: |
Interaction of TRAF6 with MAST205 regulates NF-kappaB activation and MAST205 stability. |
| Volume: |
279 |
| Issue: |
42 |
| Pages: |
43675-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sun N |
| Year: |
2020 |
| Journal: |
Protein Cell |
| Title: |
TRIM35 mediates protection against influenza infection by activating TRAF3 and degrading viral PB2. |
| Volume: |
11 |
| Issue: |
12 |
| Pages: |
894-914 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mashima R |
| Year: |
2005 |
| Journal: |
J Biol Chem |
| Title: |
FLN29, a novel interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signaling. |
| Volume: |
280 |
| Issue: |
50 |
| Pages: |
41289-97 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
He JQ |
| Year: |
2006 |
| Journal: |
J Exp Med |
| Title: |
Rescue of TRAF3-null mice by p100 NF-kappa B deficiency. |
| Volume: |
203 |
| Issue: |
11 |
| Pages: |
2413-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Matsumura T |
| Year: |
2004 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
TIFAB inhibits TIFA, TRAF-interacting protein with a forkhead-associated domain. |
| Volume: |
317 |
| Issue: |
1 |
| Pages: |
230-4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liang J |
| Year: |
2010 |
| Journal: |
J Exp Med |
| Title: |
MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-kappaB signaling. |
| Volume: |
207 |
| Issue: |
13 |
| Pages: |
2959-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li S |
| Year: |
2009 |
| Journal: |
Mol Cell |
| Title: |
PKC phosphorylation of TRAF2 mediates IKKalpha/beta recruitment and K63-linked polyubiquitination. |
| Volume: |
33 |
| Issue: |
1 |
| Pages: |
30-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vince JE |
| Year: |
2009 |
| Journal: |
J Biol Chem |
| Title: |
TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis. |
| Volume: |
284 |
| Issue: |
51 |
| Pages: |
35906-15 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Haas TL |
| Year: |
2009 |
| Journal: |
Mol Cell |
| Title: |
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction. |
| Volume: |
36 |
| Issue: |
5 |
| Pages: |
831-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sun L |
| Year: |
2004 |
| Journal: |
Mol Cell |
| Title: |
The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes. |
| Volume: |
14 |
| Issue: |
3 |
| Pages: |
289-301 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Goo HG |
| Year: |
2014 |
| Journal: |
Exp Cell Res |
| Title: |
HtrA2/Omi influences the stability of LON protease 1 and prohibitin, proteins involved in mitochondrial homeostasis. |
| Volume: |
328 |
| Issue: |
2 |
| Pages: |
456-65 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Miyazaki D |
| Year: |
2013 |
| Journal: |
Am J Pathol |
| Title: |
Pharmacologic inhibition of IκB kinase activates immediate hypersensitivity reactions in mice. |
| Volume: |
183 |
| Issue: |
1 |
| Pages: |
96-107 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li ZW |
| Year: |
1999 |
| Journal: |
J Exp Med |
| Title: |
The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis. |
| Volume: |
189 |
| Issue: |
11 |
| Pages: |
1839-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang J |
| Year: |
2007 |
| Journal: |
Mol Immunol |
| Title: |
IKK antagonizes CD95 ligation-mediated apoptosis by regulating NF-kappaB activity. |
| Volume: |
44 |
| Issue: |
8 |
| Pages: |
2139-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tang G |
| Year: |
2001 |
| Journal: |
Nature |
| Title: |
Inhibition of JNK activation through NF-kappaB target genes. |
| Volume: |
414 |
| Issue: |
6861 |
| Pages: |
313-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chae S |
| Year: |
2006 |
| Journal: |
J Immunol |
| Title: |
Epithelial cell I kappa B-kinase beta has an important protective role in Clostridium difficile toxin A-induced mucosal injury. |
| Volume: |
177 |
| Issue: |
2 |
| Pages: |
1214-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Song L |
| Year: |
2006 |
| Journal: |
J Cell Biol |
| Title: |
IKKbeta programs to turn on the GADD45alpha-MKK4-JNK apoptotic cascade specifically via p50 NF-kappaB in arsenite response. |
| Volume: |
175 |
| Issue: |
4 |
| Pages: |
607-17 |
|
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•
•
•
•
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| Publication |
| First Author: |
Hasegawa M |
| Year: |
2008 |
| Journal: |
EMBO J |
| Title: |
A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation. |
| Volume: |
27 |
| Issue: |
2 |
| Pages: |
373-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Machiyama T |
| Year: |
2018 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
TNF receptor associated factor 5 controls oncostatin M-mediated lung inflammation. |
| Volume: |
499 |
| Issue: |
3 |
| Pages: |
544-550 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kobayashi S |
| Year: |
2019 |
| Journal: |
J Immunol |
| Title: |
TNF Receptor-Associated Factor 5 Limits Function of Plasmacytoid Dendritic Cells by Controlling IFN Regulatory Factor 5 Expression. |
| Volume: |
203 |
| Issue: |
6 |
| Pages: |
1447-1456 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim N |
| Year: |
2005 |
| Journal: |
J Exp Med |
| Title: |
Osteoclast differentiation independent of the TRANCE-RANK-TRAF6 axis. |
| Volume: |
202 |
| Issue: |
5 |
| Pages: |
589-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pasparakis M |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2. |
| Volume: |
417 |
| Issue: |
6891 |
| Pages: |
861-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Helsley RN |
| Year: |
2016 |
| Journal: |
Stem Cells |
| Title: |
Targeting IκB kinase β in Adipocyte Lineage Cells for Treatment of Obesity and Metabolic Dysfunctions. |
| Volume: |
34 |
| Issue: |
7 |
| Pages: |
1883-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Emmanouil M |
| Year: |
2009 |
| Journal: |
J Immunol |
| Title: |
Neuronal I kappa B kinase beta protects mice from autoimmune encephalomyelitis by mediating neuroprotective and immunosuppressive effects in the central nervous system. |
| Volume: |
183 |
| Issue: |
12 |
| Pages: |
7877-89 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
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