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Search results 2801 to 2900 out of 6467 for Myc

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Hits by Pathway

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Hits by Strain

Type Details Score
Allele
Tg(MMTV-Myc)WT13Jrn | MGI:5524080
Name: transgene insertion WT13, Joseph R Nevins
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(MMTV-Myc)WT21Jrn | MGI:5524081
Name: transgene insertion WT21, Joseph R Nevins
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(MMTV-Myc*T58A)TA14Jrn | MGI:5524082
Name: transgene insertion TA14, Joseph R Nevins
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(MMTV-Myc*T58A)TA41Jrn | MGI:5524083
Name: transgene insertion TA41, Joseph R Nevins
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(MMTV-Myc*T58A)TA39Jrn | MGI:5524144
Name: transgene insertion TA39, Joseph R Nevins
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Gt(ROSA)26Sor<tm1(PTK2)Khd> | MGI:5704218
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Kairbaan M Hodivala-Dilke
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
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Allele
Trpc5<tm2.1Clph> | MGI:5904510
Name: transient receptor potential cation channel, subfamily C, member 5; targeted mutation 2.1, David E Clapham
Allele Type: Targeted
Attribute String: Epitope tag
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Allele
Gt(ROSA)26Sor<tm1(CAG-Fto,-GFP)Sbq> | MGI:6154621
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Shu-Bing Qian
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Col1a1<tm20(CAG-Myc,-luc2)Nki> | MGI:6324312
Name: collagen, type I, alpha 1; targeted mutation 20, The Netherlands Cancer Institute
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Col1a1<tm21(CAG-Myc,-luc2)Nki> | MGI:6324313
Name: collagen, type I, alpha 1; targeted mutation 21, The Netherlands Cancer Institute
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Reporter
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Allele
Tmc2<em1Mll> | MGI:6452848
Name: transmembrane channel-like gene family 2; endonuclease-mediated mutation 1, Ulrich Muller
Allele Type: Endonuclease-mediated
Attribute String: Epitope tag
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Allele
Gabra2<tm1(pHluorin)Stmo> | MGI:6501040
Name: gamma-aminobutyric acid type A receptor subunit alpha 2; targeted mutation 1, Stephen J Moss
Allele Type: Targeted
Attribute String: Epitope tag, Reporter
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Allele
Rr331<em1Fsp> | MGI:7410981
Name: regulatory region 331; endonuclease-mediated mutation 1, Francois Spitz
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr307328<em1Fsp> | MGI:7410984
Name: regulatory region 307328; endonuclease-mediated mutation 1, Francois Spitz
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr357<tm1.1Jta> | MGI:7434635
Name: regulatory region 357; targeted mutation 1.1, Jussi Taipale
Allele Type: Targeted
Attribute String: Modified regulatory region
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Strain
MGI:6145680 | C57BL/6J-Tg(Myh6-CCN2)13Aram/AramRbrc
Attribute String: mutant strain, coisogenic, transgenic
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Strain
MGI:6145679 | C57BL/6J-Tg(Myh6-CCN2)6Aram/AramRbrc
Attribute String: mutant strain, coisogenic, transgenic
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Allele
Tg(CAG-GFP*,-ATP6AP2)1Vli | MGI:7529127
Name: transgene insertion 1, Volkhard Lindner
Allele Type: Transgenic
Attribute String: Conditional ready, Epitope tag, Inserted expressed sequence, Reporter
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Allele
Tg(CAG-TRIM33)1Syok | MGI:7518367
Name: transgene insertion 1, Sana Yokoi
Allele Type: Transgenic
Attribute String: Epitope tag, Inserted expressed sequence
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Allele
Tg(CAG-TRIM33)5Syok | MGI:7518369
Name: transgene insertion 5, Sana Yokoi
Allele Type: Transgenic
Attribute String: Epitope tag, Inserted expressed sequence
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Allele
Tg(CAG-TRIM33)9Syok | MGI:7518371
Name: transgene insertion 9, Sana Yokoi
Allele Type: Transgenic
Attribute String: Epitope tag, Inserted expressed sequence
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Allele
Tg(CAG-TRIM33)13Syok | MGI:7518373
Name: transgene insertion 13, Sana Yokoi
Allele Type: Transgenic
Attribute String: Epitope tag, Inserted expressed sequence
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Publication
10601024 | J:59131
First Author: Hurlin PJ
Year: 1999
Journal: EMBO J
Title: Mga, a dual-specificity transcription factor that interacts with Max and contains a T-domain DNA-binding motif.
Volume: 18
Issue: 24
Pages: 7019-28
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Publication
9044833 | J:224967
First Author: Hundley JE
Year: 1997
Journal: Cancer Res
Title: Differential regulation of cell cycle characteristics and apoptosis in MMTV-myc and MMTV-ras mouse mammary tumors.
Volume: 57
Issue: 4
Pages: 600-3
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Publication
8790372 | J:108773
First Author: Santoni-Rugiu E
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of neoplastic development in the liver by hepatocyte growth factor in a transgenic mouse model.
Volume: 93
Issue: 18
Pages: 9577-82
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Publication
- | J:321631
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2022
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Regulatory Build.
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HT Experiment
GSE103219 | Haploinsufficiency for SIX2 increases nephron progenitor proliferation leading to elevated branching and nephron number
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein
Q8CB04
Organism: Mus musculus/domesticus
Length: 94  
Fragment?: true
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Protein
A0A0N4SW68
Organism: Mus musculus/domesticus
Length: 75  
Fragment?: false
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Publication
27588501 | -
First Author: Lafita-Navarro MC
Year: 2016
Journal: Oncotarget
Title: MXD1 localizes in the nucleolus, binds UBF and impairs rRNA synthesis.
Volume: 7
Issue: 43
Pages: 69536-69548
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Protein Domain
IPR040157 | MXD1
Type: Family
Description: MXD1, also known as MAD, binds Max to form a repressive transcription factor. It antagonizes MYC transcriptional activity by competing for MAX []. It has also been shown to regulate rRNA synthesis [].
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Protein
F6W2V3
Organism: Mus musculus/domesticus
Length: 104  
Fragment?: true
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Protein
Q8CEN4
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: false
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Protein
Q8BYI4
Organism: Mus musculus/domesticus
Length: 84  
Fragment?: true
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Protein
A0A0G2JGT1
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: true
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Protein
A0A0G2JE55
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: true
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Protein
A0A0A6YW42
Organism: Mus musculus/domesticus
Length: 52  
Fragment?: true
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Publication
8940189 | -
First Author: Davis-Smyth T
Year: 1996
Journal: J Biol Chem
Title: The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators.
Volume: 271
Issue: 49
Pages: 31679-87
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Publication
8125259 | -
First Author: Duncan R
Year: 1994
Journal: Genes Dev
Title: A sequence-specific, single-strand binding protein activates the far upstream element of c-myc and defines a new DNA-binding motif.
Volume: 8
Issue: 4
Pages: 465-80
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Publication
28076379 | -
First Author: Duan J
Year: 2017
Journal: PLoS One
Title: Upregulation of Far Upstream Element-Binding Protein 1 (FUBP1) Promotes Tumor Proliferation and Tumorigenesis of Clear Cell Renal Cell Carcinoma.
Volume: 12
Issue: 1
Pages: e0169852
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Publication
24845017 | -
 
First Author: Gherzi R
Year: 2014
Journal: Semin Cell Dev Biol
Title: KSRP controls pleiotropic cellular functions.
Volume: 34
Pages: 2-8
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Protein Domain
IPR033576 | CDCA7
Type: Family
Description: Cell division cycle-associated protein 7 (CDCA7/JPO1) is a transcription regulator whose expression is activated by c-Myc and by E2F1 []. CDCA7 can associate with Myc in a phosphorylation-dependent manner. CDCA7 phosphorylation by AKT leads to loss of its association with Myc []. This interaction affects Myc-dependent apoptosis and transformation [, , ]. CDCA7 has also been identified as a Notch target involved in hematopoietic stem cell emergence [].
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Protein Domain
IPR015096 | FUBP_C
Type: Domain
Description: This entry represents a domain found in the C terminus of Far upstream element-binding protein 1/2 (FUBP1/2) []. FUBP1 regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter [, ]. FUBP2, also known as KSRP (K homology-type splicing regulatory protein), is an single-strand-RNA binding protein that integrate different levels of gene expression and is required for proper immune response, lipid metabolism, cell fate decisions, and tissue regeneration [].
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Publication
8918230 | J:36472
First Author: Shimizu E
Year: 1996
Journal: Gene
Title: Expression, regulation and polymorphism of the mxi1 genes.
Volume: 176
Issue: 1-2
Pages: 45-8
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Publication
35422437 | J:324221
 
First Author: Tanaskovic N
Year: 2022
Journal: Life Sci Alliance
Title: Polycomb group ring finger protein 6 suppresses Myc-induced lymphomagenesis.
Volume: 5
Issue: 8
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Publication
12718877 | J:83093
First Author: Baudino TA
Year: 2003
Journal: Mol Cell
Title: Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss.
Volume: 11
Issue: 4
Pages: 905-14
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Publication
38714690 | J:347976
First Author: Maura F
Year: 2024
Journal: Nat Commun
Title: The genomic landscape of Vk*MYC myeloma highlights shared pathways of transformation between mice and humans.
Volume: 15
Issue: 1
Pages: 3844
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Publication
18504437 | J:140072
First Author: Calvo A
Year: 2008
Journal: Oncogene
Title: Identification of VEGF-regulated genes associated with increased lung metastatic potential: functional involvement of tenascin-C in tumor growth and lung metastasis.
Volume: 27
Issue: 40
Pages: 5373-84
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Publication
27863226 | J:238487
First Author: Liefke R
Year: 2016
Journal: Mol Cell
Title: EPOP Interacts with Elongin BC and USP7 to Modulate the Chromatin Landscape.
Volume: 64
Issue: 4
Pages: 659-672
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Publication
26232096 | J:226423
First Author: Chung B
Year: 2015
Journal: Diabetologia
Title: The diabetes gene Zfp69 modulates hepatic insulin sensitivity in mice.
Volume: 58
Issue: 10
Pages: 2403-13
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Publication
8786139 | J:33857
First Author: Lavenu A
Year: 1996
Journal: Genomics
Title: Genomic structure and precise mapping of a thymic regulatory region on mouse chromosome 17 revealed by a c-myc transgene insertion.
Volume: 34
Issue: 3
Pages: 381-8
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Strain
MGI:2161724 | B6.Cg-Tg(IghMyc)22Bri/J
Attribute String: mutant strain, transgenic, congenic
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Publication
9049182 | J:39684
First Author: Prasad VS
Year: 1997
Journal: Mol Carcinog
Title: Upregulation of endogenous p53 and induction of in vivo apoptosis in B-lineage lymphomas of E(mu)-myc transgenic mice by deregulated c-myc transgene.
Volume: 18
Issue: 2
Pages: 66-77
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Publication
19800577 | J:153707
First Author: Bric A
Year: 2009
Journal: Cancer Cell
Title: Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model.
Volume: 16
Issue: 4
Pages: 324-35
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Publication
33608271 | J:314001
 
First Author: Grandjean CL
Year: 2021
Journal: Sci Adv
Title: Imaging the mechanisms of anti-CD20 therapy in vivo uncovers spatiotemporal bottlenecks in antibody-dependent phagocytosis.
Volume: 7
Issue: 8
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Publication
20587527 | J:162462
First Author: Shah MY
Year: 2010
Journal: Cancer Res
Title: DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.
Volume: 70
Issue: 14
Pages: 5840-50
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Publication
35857457 | J:327247
First Author: Grima-Reyes M
Year: 2022
Journal: Sci Adv
Title: Tumoral microenvironment prevents de novo asparagine biosynthesis in B cell lymphoma, regardless of ASNS expression.
Volume: 8
Issue: 27
Pages: eabn6491
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Publication
30827861 | J:276002
First Author: Chiche J
Year: 2019
Journal: Cell Metab
Title: GAPDH Expression Predicts the Response to R-CHOP, the Tumor Metabolic Status, and the Response of DLBCL Patients to Metabolic Inhibitors.
Volume: 29
Issue: 6
Pages: 1243-1257.e10
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Publication
22789538 | J:187617
First Author: Bywater MJ
Year: 2012
Journal: Cancer Cell
Title: Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.
Volume: 22
Issue: 1
Pages: 51-65
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Publication
18922927 | J:140661
First Author: Mori S
Year: 2008
Journal: Cancer Res
Title: Utilization of pathway signatures to reveal distinct types of B lymphoma in the Emicro-myc model and human diffuse large B-cell lymphoma.
Volume: 68
Issue: 20
Pages: 8525-34
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Publication
20161707 | J:158000
First Author: Repellin CE
Year: 2010
Journal: PLoS One
Title: Lymphoid hyperplasia and lymphoma in transgenic mice expressing the small non-coding RNA, EBER1 of Epstein-Barr virus.
Volume: 5
Issue: 2
Pages: e9092
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Publication
25732831 | J:222110
First Author: Aubrey BJ
Year: 2015
Journal: Cell Rep
Title: An inducible lentiviral guide RNA platform enables the identification of tumor-essential genes and tumor-promoting mutations in vivo.
Volume: 10
Issue: 8
Pages: 1422-32
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Publication
25394713 | J:220619
First Author: Chiche J
Year: 2015
Journal: Leukemia
Title: GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin's B lymphomas via NF-κB-dependent induction of HIF-1α.
Volume: 29
Issue: 5
Pages: 1163-76
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Publication
24292681 | J:216558
First Author: Newbold A
Year: 2014
Journal: Oncogene
Title: The role of p21(waf1/cip1) and p27(Kip1) in HDACi-mediated tumor cell death and cell cycle arrest in the Eμ-myc model of B-cell lymphoma.
Volume: 33
Issue: 47
Pages: 5415-23
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Publication
23169636 | J:192330
First Author: Bénéteau M
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Combination of glycolysis inhibition with chemotherapy results in an antitumor immune response.
Volume: 109
Issue: 49
Pages: 20071-6
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Publication
26184912 | J:258579
First Author: Carter MJ
Year: 2016
Journal: Cell Death Differ
Title: BCR-signaling-induced cell death demonstrates dependency on multiple BH3-only proteins in a murine model of B-cell lymphoma.
Volume: 23
Issue: 2
Pages: 303-12
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Publication
35952646 | J:327877
First Author: Lu H
Year: 2022
Journal: Cell Host Microbe
Title: Butyrate-producing Eubacterium rectale suppresses lymphomagenesis by alleviating the TNF-induced TLR4/MyD88/NF-κB axis.
Volume: 30
Issue: 8
Pages: 1139-1150.e7
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Publication
25865892 | J:228387
First Author: Shen YJ
Year: 2015
Journal: Cell Rep
Title: Genome-derived cytosolic DNA mediates type I interferon-dependent rejection of B cell lymphoma cells.
Volume: 11
Issue: 3
Pages: 460-73
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Publication
35624087 | J:325279
First Author: Thürmer M
Year: 2022
Journal: Nat Commun
Title: PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling.
Volume: 13
Issue: 1
Pages: 2982
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Publication
12242653 | J:79057
First Author: Mikkers H
Year: 2002
Journal: Oncogene
Title: Proviral activation of the tumor suppressor E2a contributes to T cell lymphomagenesis in EmuMyc transgenic mice.
Volume: 21
Issue: 43
Pages: 6559-66
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Publication
26888257 | J:232931
First Author: Lykken JM
Year: 2016
Journal: Blood
Title: Galectin-1 drives lymphoma CD20 immunotherapy resistance: validation of a preclinical system to identify resistance mechanisms.
Volume: 127
Issue: 15
Pages: 1886-95
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Publication
19783987 | J:155132
First Author: Meacham CE
Year: 2009
Journal: Nat Genet
Title: In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression.
Volume: 41
Issue: 10
Pages: 1133-7
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Publication
18593934 | J:138876
First Author: Lin CJ
Year: 2008
Journal: Cancer Res
Title: c-Myc and eIF4F are components of a feedforward loop that links transcription and translation.
Volume: 68
Issue: 13
Pages: 5326-34
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Allele
Hprt1<tm6Detl> | MGI:2668521
 
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 6, Peter J Detloff
Allele Type: Targeted
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Allele
Hprt1<tm7Detl> | MGI:2668522
 
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 7, Peter J Detloff
Allele Type: Targeted
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Strain
MGI:4437269 | FVB.Cg-Tg(IghMyc)186Brn/Cnrm
Attribute String: congenic, mutant strain, transgenic
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Publication
18223157 | J:143963
First Author: Unni AM
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Intrinsic sensor of oncogenic transformation induces a signal for innate immunosurveillance.
Volume: 105
Issue: 5
Pages: 1686-91
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Allele
Tg(Ela1-Myc)159Bri | MGI:3511167
Name: transgene insertion 159, Ralph L Brinster
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Axin1<tm1(Axin2)Cos> | MGI:3580422
Name: axin 1; targeted mutation 1, Frank Costantini
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Null/knockout
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Allele
Bmp7<tm3(Bmp7)Rob> | MGI:3611800
 
Name: bone morphogenetic protein 7; targeted mutation 3, Elizabeth J Robertson
Allele Type: Targeted
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Allele
Rp1<tm1Eap> | MGI:3652902
Name: retinitis pigmentosa 1 (human); targeted mutation 1, Eric A Pierce
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Trim63<tm1.1Vlcg> | MGI:3851099
Name: tripartite motif-containing 63; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Pkd1<tm3.2Bol> | MGI:4366015
Name: polycystin 1, transient receptor potential channel interacting; targeted mutation 3.2, Alessandra Boletta
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Tg(TetO-Axin1,-EGFP)TA32Cos | MGI:4947394
Name: transgene insertion TA32, Franklin Costantini
Allele Type: Transgenic
Attribute String: Epitope tag, Inducible, Inserted expressed sequence, Reporter
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Allele
Tg(Ttr-Hfe*)1Nca | MGI:4948232
Name: transgene insertion 1, Nancy C Andrews
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Gt(ROSA)26Sor<tm2(MYC/ERT)Hsc> | MGI:5000147
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Hubert Schorle
Allele Type: Targeted
Attribute String: Conditional ready, Inducible, Inserted expressed sequence
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Strain
MGI:6146180 | B6.Cg-Tg(Thy1-BSCL2*N88S)1Dit/Rbrc
Attribute String: mutant strain, congenic, transgenic
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Publication
21750110 | J:175537
First Author: Yagi T
Year: 2011
Journal: Hum Mol Genet
Title: N88S seipin mutant transgenic mice develop features of seipinopathy/BSCL2-related motor neuron disease via endoplasmic reticulum stress.
Volume: 20
Issue: 19
Pages: 3831-40
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Publication
22045697 | J:179714
First Author: Ito D
Year: 2012
Journal: Hum Mol Genet
Title: Characterization of inclusion bodies with cytoprotective properties formed by seipinopathy-linked mutant seipin.
Volume: 21
Issue: 3
Pages: 635-46
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Allele
Gt(ROSA)26Sor<tm13(CAG-MYC,-CD2*)Rsky> | MGI:5444670
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 13, Klaus Rajewsky
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
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Allele
Rr21<tm1Jta> | MGI:5463412
Name: regulatory region 21; targeted mutation 1, Jussi Taipale
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Tg(H2-K-IL6)2Srj | MGI:5582513
Name: transgene insertion 2, Stefan Rose-John
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Dnaaf6rt<tm1.1Hmd> | MGI:5609302
Name: dynein axonemal assembly factor 6, retrotransposed; targeted mutation 1.1, Hiroshi Hamada
Allele Type: Targeted
Attribute String: Conditional ready, Reporter
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Allele
Gt(ROSA)26Sor<tm2(PTK2*Y397F)Khd> | MGI:5704220
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Kairbaan M Hodivala-Dilke
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
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Allele
Gt(ROSA)26Sor<tm3(PTK2*Y397E)Khd> | MGI:5704292
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Kairbaan M Hodivala-Dilke
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
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Allele
Gt(ROSA)26Sor<tm6(PTK2*Y861F)Khd> | MGI:5704300
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 6, Kairbaan M Hodivala-Dilke
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
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Allele
Rr38<tm1.1Aafo> | MGI:5750932
Name: regulatory region 38; targeted mutation 1.1, Adolfo A Ferrando
Allele Type: Targeted
Attribute String: Conditional ready, Modified regulatory region, No functional change
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Allele
Rr38<tm1.2Aafo> | MGI:5750934
Name: regulatory region 38; targeted mutation 1.2, Adolfo A Ferrando
Allele Type: Targeted
Attribute String: Modified regulatory region, Null/knockout
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Strain
MGI:5904511 | 129S1/SvImJ-Trpc5<tm2.1Clph>/J
Attribute String: coisogenic
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Allele
Tg(Hoxb13-Myc)1Cbie | MGI:5908179
Name: transgene insertion 1, Charles Bieberich
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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