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Search results 2801 to 2900 out of 2905 for Pdx1

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Type Details Score
Publication
30361701 | J:268101
First Author: Cigliola V
Year: 2018
Journal: Nat Cell Biol
Title: Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon+ α-cells.
Volume: 20
Issue: 11
Pages: 1267-1277
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Publication
29017057 | J:243744
First Author: Mello SS
Year: 2017
Journal: Cancer Cell
Title: A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer.
Volume: 32
Issue: 4
Pages: 460-473.e6
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Publication
35976056 | J:330251
 
First Author: Sun C
Year: 2022
Journal: Dis Model Mech
Title: Context matters - Daxx and Atrx are not robust tumor suppressors in the murine endocrine pancreas.
Volume: 15
Issue: 8
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Publication
28432216 | J:241569
First Author: Higashiyama H
Year: 2017
Journal: Development
Title: Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient mouse model of biliary atresia.
Volume: 144
Issue: 10
Pages: 1906-1917
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hmga2/Hmga2<+> Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53<+>
Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd9/Cd9<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53
Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129X1/SvJ * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd9/Cd9 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53<+>
Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129X1/SvJ * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd9/Cd9<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53<+>
Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129X1/SvJ * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd9/Cd9 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53
Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129X1/SvJ * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(Pdx1-flpo)#Ybi/?
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac
Zygosity: cn
Has Mutant Allele: true
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Protein
Q6XP49
Organism: Mus musculus/domesticus
Length: 780  
Fragment?: false
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Protein
A2AWH8
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: false
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Protein
A2AWH7
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: true
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Protein
Q0GE24
Organism: Mus musculus/domesticus
Length: 935  
Fragment?: false
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Protein
A2VDF9
Organism: Mus musculus/domesticus
Length: 802  
Fragment?: true
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Publication
20562852 | J:162641
First Author: Marcheva B
Year: 2010
Journal: Nature
Title: Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes.
Volume: 466
Issue: 7306
Pages: 627-31
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Publication
21362568 | J:171126
First Author: Smukler SR
Year: 2011
Journal: Cell Stem Cell
Title: The adult mouse and human pancreas contain rare multipotent stem cells that express insulin.
Volume: 8
Issue: 3
Pages: 281-93
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Publication
31509750 | J:281075
First Author: Xue J
Year: 2019
Journal: Cell Rep
Title: CDK8 Regulates Insulin Secretion and Mediates Postnatal and Stress-Induced Expression of Neuropeptides in Pancreatic β Cells.
Volume: 28
Issue: 11
Pages: 2892-2904.e7
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Publication
16397221 | J:105031
First Author: Hruban RH
Year: 2006
Journal: Cancer Res
Title: Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations.
Volume: 66
Issue: 1
Pages: 95-106
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Publication
28031255 | J:240629
First Author: Rath N
Year: 2017
Journal: EMBO Mol Med
Title: ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth.
Volume: 9
Issue: 2
Pages: 198-218
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Publication
24085033 | J:204991
First Author: Pasek RC
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Advancements and challenges in generating accurate animal models of gestational diabetes mellitus.
Volume: 305
Issue: 11
Pages: E1327-38
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Publication
30120146 | J:286040
 
First Author: Chen Y
Year: 2018
Journal: EMBO Mol Med
Title: Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program.
Volume: 10
Issue: 10
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Publication
25774850 | J:228179
First Author: Marquard J
Year: 2015
Journal: Nat Med
Title: Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment.
Volume: 21
Issue: 4
Pages: 363-72
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Publication
31653840 | J:279957
First Author: Bufe B
Year: 2019
Journal: Nat Commun
Title: Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour.
Volume: 10
Issue: 1
Pages: 4889
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Publication
29844119 | J:265549
First Author: Cheung PF
Year: 2018
Journal: Cancer Res
Title: Notch-Induced Myeloid Reprogramming in Spontaneous Pancreatic Ductal Adenocarcinoma by Dual Genetic Targeting.
Volume: 78
Issue: 17
Pages: 4997-5010
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Publication
20645310 | J:164697
First Author: Vincent DF
Year: 2010
Journal: Genesis
Title: A rapid strategy to detect the recombined allele in LSL-TβRICA transgenic mice.
Volume: 48
Issue: 9
Pages: 559-62
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Publication
28049824 | J:239540
First Author: Zhang G
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: p53 pathway is involved in cell competition during mouse embryogenesis.
Volume: 114
Issue: 3
Pages: 498-503
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Publication
27569912 | J:236387
First Author: Daley D
Year: 2016
Journal: Cell
Title: γδ T Cells Support Pancreatic Oncogenesis by Restraining αβ T Cell Activation.
Volume: 166
Issue: 6
Pages: 1485-1499.e15
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Publication
21205788 | J:169830
First Author: Kopinke D
Year: 2011
Journal: Development
Title: Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas.
Volume: 138
Issue: 3
Pages: 431-41
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Publication
37171959 | J:337581
First Author: Lacombe J
Year: 2023
Journal: Cell Rep
Title: Vitamin K-dependent carboxylation regulates Ca(2+) flux and adaptation to metabolic stress in β cells.
Volume: 42
Issue: 5
Pages: 112500
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Publication
20071774 | J:156681
First Author: Morris JP 4th
Year: 2010
Journal: J Clin Invest
Title: Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice.
Volume: 120
Issue: 2
Pages: 508-20
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Publication
23467612 | J:197052
First Author: Lin WC
Year: 2013
Journal: Cancer Res
Title: Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer.
Volume: 73
Issue: 6
Pages: 1821-30
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Publication
29808009 | J:336458
First Author: Ruess DA
Year: 2018
Journal: Nat Med
Title: Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase.
Volume: 24
Issue: 7
Pages: 954-960
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Publication
25939753 | J:222769
First Author: Bednar F
Year: 2015
Journal: Carcinogenesis
Title: Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism.
Volume: 36
Issue: 7
Pages: 730-8
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Publication
35122074 | J:322704
First Author: Falcomatà C
Year: 2022
Journal: Nat Cancer
Title: Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment.
Volume: 3
Issue: 3
Pages: 318-336
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Publication
29153842 | J:252273
First Author: Todoric J
Year: 2017
Journal: Cancer Cell
Title: Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.
Volume: 32
Issue: 6
Pages: 824-839.e8
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Publication
36351408 | J:331107
First Author: Ramakrishnan G
Year: 2022
Journal: Cell Rep
Title: NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma.
Volume: 41
Issue: 6
Pages: 111623
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Publication
30842658 | J:274344
First Author: Lee JW
Year: 2019
Journal: Nature
Title: Hepatocytes direct the formation of a pro-metastatic niche in the liver.
Volume: 567
Issue: 7747
Pages: 249-252
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Publication
35523176 | J:325642
First Author: Huang H
Year: 2022
Journal: Cancer Cell
Title: Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer.
Volume: 40
Issue: 6
Pages: 656-673.e7
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Publication
29069604 | J:254840
First Author: Ferreira RMM
Year: 2017
Journal: Cell Rep
Title: Duct- and Acinar-Derived Pancreatic Ductal Adenocarcinomas Show Distinct Tumor Progression and Marker Expression.
Volume: 21
Issue: 4
Pages: 966-978
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Publication
32541668 | J:291708
First Author: Perkail S
Year: 2020
Journal: Nat Commun
Title: BAP1 is a haploinsufficient tumor suppressor linking chronic pancreatitis to pancreatic cancer in mice.
Volume: 11
Issue: 1
Pages: 3018
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Publication
26123485 | J:222392
First Author: Liu G
Year: 2015
Journal: Hum Mol Genet
Title: Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression.
Volume: 24
Issue: 18
Pages: 5299-312
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Publication
19939939 | J:166881
First Author: Kim I
Year: 2009
Journal: J Am Soc Nephrol
Title: Conditional mutation of Pkd2 causes cystogenesis and upregulates beta-catenin.
Volume: 20
Issue: 12
Pages: 2556-69
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Publication
34385258 | J:321932
First Author: Rovira M
Year: 2021
Journal: Genes Dev
Title: REST is a major negative regulator of endocrine differentiation during pancreas organogenesis.
Volume: 35
Issue: 17-18
Pages: 1229-1242
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Publication
28813661 | J:260582
First Author: Zhu Y
Year: 2017
Journal: Immunity
Title: Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression.
Volume: 47
Issue: 2
Pages: 323-338.e6
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Publication
37341148 | J:338218
First Author: Tsuyama T
Year: 2023
Journal: EMBO Rep
Title: Hypoxia causes pancreatic β-cell dysfunction and impairs insulin secretion by activating the transcriptional repressor BHLHE40.
Volume: 24
Issue: 8
Pages: e56227
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Publication
28425994 | J:254425
First Author: Maddocks ODK
Year: 2017
Journal: Nature
Title: Modulating the therapeutic response of tumours to dietary serine and glycine starvation.
Volume: 544
Issue: 7650
Pages: 372-376
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Publication
31390573 | J:280212
First Author: Talbert EE
Year: 2019
Journal: Cell Rep
Title: Modeling Human Cancer-induced Cachexia.
Volume: 28
Issue: 6
Pages: 1612-1622.e4
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Publication
36351945 | J:331101
First Author: Sodir NM
Year: 2022
Journal: Nat Commun
Title: Reversible Myc hypomorphism identifies a key Myc-dependency in early cancer evolution.
Volume: 13
Issue: 1
Pages: 6782
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Publication
24743474 | J:215194
First Author: Dow LE
Year: 2014
Journal: PLoS One
Title: Conditional reverse tet-transactivator mouse strains for the efficient induction of TRE-regulated transgenes in mice.
Volume: 9
Issue: 4
Pages: e95236
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Publication
24280215 | J:207177
First Author: Zhou Y
Year: 2014
Journal: J Biol Chem
Title: Proteome analysis and conditional deletion of the EAAT2 glutamate transporter provide evidence against a role of EAAT2 in pancreatic insulin secretion in mice.
Volume: 289
Issue: 3
Pages: 1329-44
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Publication
32154941 | J:288604
First Author: Kalisz M
Year: 2020
Journal: EMBO J
Title: HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer.
Volume: 39
Issue: 9
Pages: e102808
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Publication
31048544 | J:289183
First Author: Wang L
Year: 2019
Journal: Genes Dev
Title: ATDC is required for the initiation of KRAS-induced pancreatic tumorigenesis.
Volume: 33
Issue: 11-12
Pages: 641-655
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Publication
30952657 | J:276349
First Author: Poulin EJ
Year: 2019
Journal: Cancer Discov
Title: Tissue-Specific Oncogenic Activity of KRASA146T.
Volume: 9
Issue: 6
Pages: 738-755
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Publication
31439548 | J:280029
First Author: Mizutani Y
Year: 2019
Journal: Cancer Res
Title: Meflin-Positive Cancer-Associated Fibroblasts Inhibit Pancreatic Carcinogenesis.
Volume: 79
Issue: 20
Pages: 5367-5381
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Publication
27281208 | J:235743
First Author: Fox RG
Year: 2016
Journal: Nature
Title: Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.
Volume: 534
Issue: 7607
Pages: 407-411
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Publication
30996350 | J:280283
First Author: Shi Y
Year: 2019
Journal: Nature
Title: Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring.
Volume: 569
Issue: 7754
Pages: 131-135
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Publication
30010625 | J:265678
First Author: Tsuda M
Year: 2018
Journal: J Clin Invest
Title: The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis.
Volume: 128
Issue: 8
Pages: 3475-3489
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Publication
31548432 | J:280398
First Author: Mameishvili E
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer.
Volume: 116
Issue: 41
Pages: 20679-20688
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Protein
Q8BMF4
Organism: Mus musculus/domesticus
Length: 642  
Fragment?: false
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Protein
Q8BKZ9
Organism: Mus musculus/domesticus
Length: 501  
Fragment?: false
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Publication
28053125 | J:240920
First Author: Cain-Hom C
Year: 2017
Journal: Nucleic Acids Res
Title: Efficient mapping of transgene integration sites and local structural changes in Cre transgenic mice using targeted locus amplification.
Volume: 45
Issue: 8
Pages: e62
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Publication
31451639 | J:279325
First Author: Chang H
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Efficient genome-wide first-generation phenotypic screening system in mice using the piggyBac transposon.
Volume: 116
Issue: 37
Pages: 18507-18516
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Publication
25485836 | J:220259
First Author: Rad R
Year: 2015
Journal: Nat Genet
Title: A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer.
Volume: 47
Issue: 1
Pages: 47-56
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Publication
22034435 | J:177853
First Author: Shakya R
Year: 2011
Journal: Science
Title: BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity.
Volume: 334
Issue: 6055
Pages: 525-8
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Publication
29223399 | J:268568
First Author: Kim H
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Ectopic serotonin production in β-cell specific transgenic mice.
Volume: 495
Issue: 2
Pages: 1986-1991
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Publication
33741967 | J:303829
First Author: Alicea-Torres K
Year: 2021
Journal: Nat Commun
Title: Immune suppressive activity of myeloid-derived suppressor cells in cancer requires inactivation of the type I interferon pathway.
Volume: 12
Issue: 1
Pages: 1717
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Publication
26119937 | J:234215
First Author: Hessmann E
Year: 2016
Journal: Oncogene
Title: MYC in pancreatic cancer: novel mechanistic insights and their translation into therapeutic strategies.
Volume: 35
Issue: 13
Pages: 1609-18
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Publication
33990661 | J:314449
First Author: Shrivastava V
Year: 2021
Journal: Sci Rep
Title: Beta cell adaptation to pregnancy requires prolactin action on both beta and non-beta cells.
Volume: 11
Issue: 1
Pages: 10372
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Publication
31937792 | J:292860
First Author: Sakamoto K
Year: 2020
Journal: Sci Rep
Title: Efficient tissue-type specific expression of target genes in a tetracycline-controlled manner from the ubiquitously active Eef1a1 locus.
Volume: 10
Issue: 1
Pages: 207
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Publication
33810510 | J:307755
 
First Author: Poelaert BJ
Year: 2021
Journal: Cancers (Basel)
Title: Amyloid Precursor-like Protein 2 Expression Increases during Pancreatic Cancer Development and Shortens the Survival of a Spontaneous Mouse Model of Pancreatic Cancer.
Volume: 13
Issue: 7
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Publication
26261055 | J:236511
 
First Author: Yu R
Year: 2016
Journal: Mol Cell Endocrinol
Title: Animal models of spontaneous pancreatic neuroendocrine tumors.
Volume: 421
Pages: 60-7
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Publication
33667385 | J:303521
First Author: Chen Y
Year: 2021
Journal: Cancer Cell
Title: Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer.
Volume: 39
Issue: 4
Pages: 548-565.e6
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Publication
28178232 | J:243963
First Author: Genovese G
Year: 2017
Journal: Nature
Title: Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer.
Volume: 542
Issue: 7641
Pages: 362-366
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Publication
28249168 | J:256196
First Author: Rajbhandari N
Year: 2017
Journal: Cell Rep
Title: Autocrine IGF1 Signaling Mediates Pancreatic Tumor Cell Dormancy in the Absence of Oncogenic Drivers.
Volume: 18
Issue: 9
Pages: 2243-2255
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Publication
20018721 | J:156461
First Author: Morton JP
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer.
Volume: 107
Issue: 1
Pages: 246-51
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Publication
33626352 | J:304305
First Author: Tomita H
Year: 2021
Journal: Cell Rep
Title: Inhibition of FGF10-ERK signal activation suppresses intraductal papillary neoplasm of the bile duct and its associated carcinomas.
Volume: 34
Issue: 8
Pages: 108772
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Publication
29920276 | J:263869
First Author: Parajuli P
Year: 2018
Journal: Dev Cell
Title: Twist1 Activation in Muscle Progenitor Cells Causes Muscle Loss Akin to Cancer Cachexia.
Volume: 45
Issue: 6
Pages: 712-725.e6
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Publication
26592448 | J:228015
First Author: Diersch S
Year: 2016
Journal: Oncogene
Title: Kras(G12D) induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells.
Volume: 35
Issue: 29
Pages: 3880-6
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Publication
30926808 | J:273330
First Author: Barilla RM
Year: 2019
Journal: Nat Commun
Title: Specialized dendritic cells induce tumor-promoting IL-10+IL-17+ FoxP3neg regulatory CD4+ T cells in pancreatic carcinoma.
Volume: 10
Issue: 1
Pages: 1424
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Publication
27292635 | J:238302
First Author: Byrne KT
Year: 2016
Journal: Cell Rep
Title: CD40 Stimulation Obviates Innate Sensors and Drives T Cell Immunity in Cancer.
Volume: 15
Issue: 12
Pages: 2719-32
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Publication
37345534 | J:338197
     
First Author: Nakamura T
Year: 2023
Journal: J Pathol
Title: ELF3 suppresses gallbladder cancer development through downregulation of the EREG/EGFR/mTOR complex 1 signalling pathway.
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Publication
32355214 | J:297756
First Author: Zebertavage LK
Year: 2020
Journal: Sci Rep
Title: Transcriptional Upregulation of NLRC5 by Radiation Drives STING- and Interferon-Independent MHC-I Expression on Cancer Cells and T Cell Cytotoxicity.
Volume: 10
Issue: 1
Pages: 7376
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Publication
28325479 | J:251956
First Author: Chambers AP
Year: 2017
Journal: Cell Metab
Title: The Role of Pancreatic Preproglucagon in Glucose Homeostasis in Mice.
Volume: 25
Issue: 4
Pages: 927-934.e3
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Publication
27721407 | J:241090
First Author: Stojanovic N
Year: 2017
Journal: Oncogene
Title: HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer.
Volume: 36
Issue: 13
Pages: 1804-1815
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Publication
32304665 | J:290208
First Author: Chung KM
Year: 2020
Journal: Cell
Title: Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma.
Volume: 181
Issue: 4
Pages: 832-847.e18
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