|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 2801 to 2900 out of 8321 for Src

0.032s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
GXD Expression  
Probe: MGI:1620549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828053
Age: embryonic day 14.5
Image: euxassay_003020_06
Specimen Label: euxassay_003020_06
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1620549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828053
Age: embryonic day 14.5
Image: euxassay_003020_07
Specimen Label: euxassay_003020_07
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1620549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828053
Age: embryonic day 14.5
Image: euxassay_003020_20
Specimen Label: euxassay_003020_20
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:1620549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828053
Age: embryonic day 14.5
Image: euxassay_003020_21
Specimen Label: euxassay_003020_21
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:7328571
Assay Type: Immunohistochemistry
Annotation Date: 2022-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160464
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:7328575
Age: embryonic day 3.5
Note: Expression is at the cell periphery.
Specimen Label: 2F
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:1620549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828054
Age: embryonic day 14.5
Image: euxassay_001116_07
Specimen Label: euxassay_001116_07
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1620549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828054
Age: embryonic day 14.5
Image: euxassay_001116_08
Specimen Label: euxassay_001116_08
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:1620549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828054
Age: embryonic day 14.5
Image: euxassay_001116_19
Specimen Label: euxassay_001116_19
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:1620549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828053
Age: embryonic day 14.5
Image: euxassay_003020_07
Specimen Label: euxassay_003020_07
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1620549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828053
Age: embryonic day 14.5
Image: euxassay_003020_08
Specimen Label: euxassay_003020_08
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:1620549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828053
Age: embryonic day 14.5
Image: euxassay_003020_17
Specimen Label: euxassay_003020_17
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:1620549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828053
Age: embryonic day 14.5
Image: euxassay_003020_18
Specimen Label: euxassay_003020_18
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_08
Specimen Label: euxassay_009465_08
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_10
Specimen Label: euxassay_009465_10
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_11
Specimen Label: euxassay_009465_11
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_12
Specimen Label: euxassay_009465_12
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_13
Specimen Label: euxassay_009465_13
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_14
Specimen Label: euxassay_009465_14
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_15
Specimen Label: euxassay_009465_15
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_16
Specimen Label: euxassay_009465_16
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_17
Specimen Label: euxassay_009465_17
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_18
Specimen Label: euxassay_009465_18
Detected: true
Specimen Num: 17
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692930
Age: postnatal adult
Image: BCM_2398594
Specimen Label: BCM_2398594
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692930
Age: postnatal adult
Image: BCM_2398589
Specimen Label: BCM_2398589
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:1620549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828054
Age: embryonic day 14.5
Image: euxassay_001116_12
Specimen Label: euxassay_001116_12
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1620549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828054
Age: embryonic day 14.5
Image: euxassay_001116_13
Specimen Label: euxassay_001116_13
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:1620549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828054
Age: embryonic day 14.5
Image: euxassay_001116_14
Specimen Label: euxassay_001116_14
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_07
Specimen Label: euxassay_009465_07
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_08
Specimen Label: euxassay_009465_08
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_09
Specimen Label: euxassay_009465_09
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_10
Specimen Label: euxassay_009465_10
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_11
Specimen Label: euxassay_009465_11
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_12
Specimen Label: euxassay_009465_12
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_13
Specimen Label: euxassay_009465_13
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_15
Specimen Label: euxassay_009465_15
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_16
Specimen Label: euxassay_009465_16
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4423986
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828048
Age: embryonic day 14.5
Image: euxassay_009465_17
Specimen Label: euxassay_009465_17
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:7328571
Assay Type: Immunohistochemistry
Annotation Date: 2022-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Not Specified
Stage: TS02
Assay Id: MGI:7328575
Age: embryonic day 1.0
Note: Expression is throughout the cytoplasm.
Specimen Label: 2B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1620549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679823
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828054
Age: embryonic day 14.5
Image: euxassay_001116_09
Specimen Label: euxassay_001116_09
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:1620549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679823
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828054
Age: embryonic day 14.5
Image: euxassay_001116_10
Specimen Label: euxassay_001116_10
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:1620549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679823
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828054
Age: embryonic day 14.5
Image: euxassay_001116_17
Specimen Label: euxassay_001116_17
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:1620549
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679823
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828054
Age: embryonic day 14.5
Image: euxassay_001116_18
Specimen Label: euxassay_001116_18
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_11
Specimen Label: euxassay_009466_11
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_12
Specimen Label: euxassay_009466_12
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_16
Specimen Label: euxassay_009466_16
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4423987
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828050
Age: embryonic day 14.5
Image: euxassay_009466_17
Specimen Label: euxassay_009466_17
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4944263
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4946256
Age: embryonic day 12.5
Image: 3 E12.5
Specimen Label: 3 E12.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4944267
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4946258
Age: embryonic day 12.5
Image: 3 E12.5
Specimen Label: 3 E12.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6159694
Assay Type: RNA in situ
Annotation Date: 2018-06-06
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6159758
Age: postnatal week 10
Note: Authors state that expression was negligible in the various regions of the brain.
Specimen Label: not shown
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692930
Age: postnatal adult
Image: BCM_2398593
Specimen Label: BCM_2398593
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692930
Age: postnatal adult
Image: BCM_2398583
Specimen Label: BCM_2398583
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692930
Age: postnatal adult
Image: BCM_2398584
Specimen Label: BCM_2398584
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692930
Age: postnatal adult
Image: BCM_2398587
Specimen Label: BCM_2398587
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:4425034
Assay Type: RNA in situ
Annotation Date: 2023-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1786922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7444286
Age: embryonic day 14.5
Image: S1C
Note: Expression was detected throughout the valve endothelium.
Specimen Label: S1C
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7316397
Assay Type: RNA in situ
Annotation Date: 2022-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3747123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7316567
Age: embryonic day 15.5
Note: Expression is in the ventricular and subventricular zone.
Specimen Label: S1CC
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7316397
Assay Type: RNA in situ
Annotation Date: 2022-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3747123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7316567
Age: embryonic day 15.5
Note: Expression is reduced in this mutant compared to controls.
Specimen Label: S1CC'
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7316397
Assay Type: RNA in situ
Annotation Date: 2022-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3746923
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7316567
Age: embryonic day 15.5
Specimen Label: S1DD
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:7316397
Assay Type: RNA in situ
Annotation Date: 2022-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3746923
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7316567
Age: embryonic day 15.5
Note: Expression is reduced in this mutant compared to controls.
Specimen Label: S1DD'
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:4425034
Assay Type: RNA in situ
Annotation Date: 2023-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3805122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7444286
Age: embryonic day 14.5
Image: S1C
Note: Expression was detected throughout the trabecular endocardium.
Specimen Label: S1C
Detected: true
Specimen Num: 1
Publication
First Author: Burbach BJ
Year: 2011
Journal: J Immunol
Title: The pleckstrin homology domain in the SKAP55 adapter protein defines the ability of the adapter protein ADAP to regulate integrin function and NF-kappaB activation.
Volume: 186
Issue: 11
Pages: 6227-37
Publication
First Author: Timms JF
Year: 1999
Journal: Curr Biol
Title: SHPS-1 is a scaffold for assembling distinct adhesion-regulated multi-protein complexes in macrophages.
Volume: 9
Issue: 16
Pages: 927-30
Publication
First Author: Meng F
Year: 1998
Journal: EMBO J
Title: A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration.
Volume: 17
Issue: 15
Pages: 4391-403
Interaction Experiment
Description: Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways.
Interaction Experiment
Description: The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules.
Interaction Experiment
Description: A role for CAP, a novel, multifunctional Src homology 3 domain-containing protein in formation of actin stress fibers and focal adhesions.
Interaction Experiment
Description: A hrs binding protein having a Src homology 3 domain is involved in intracellular degradation of growth factors and their receptors.
Interaction Experiment
Description: Src homology 2 (SH2)-containing 5-inositol phosphatase localizes to podosomes, and the SH2 domain is implicated in the attenuation of bone resorption in osteoclasts.
Interaction Experiment
Description: Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade.
Interaction Experiment
Description: A caveolin-3 mutant that causes limb girdle muscular dystrophy type 1C disrupts Src localization and activity and induces apoptosis in skeletal myotubes.
Interaction Experiment
Description: Regulation of CDC42 GTPase by proline-rich tyrosine kinase 2 interacting with PSGAP, a novel pleckstrin homology and Src homology 3 domain containing rhoGAP protein.
Interaction Experiment
Description: mSiglec-E, a novel mouse CD33-related siglec (sialic acid-binding immunoglobulin-like lectin) that recruits Src homology 2 (SH2)-domain-containing protein tyrosine phosphatases SHP-1 and SHP-2.
Interaction Experiment
Description: Rhodocytin induces platelet aggregation by interacting with glycoprotein Ia/IIa (GPIa/IIa, Integrin alpha 2beta 1). Involvement of GPIa/IIa-associated src and protein tyrosine phosphorylation.
Interaction Experiment
Description: A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain.
Interaction Experiment
Description: Using a phage display library to identify basic residues in A-Raf required to mediate binding to the Src homology 2 domains of the p85 subunit of phosphatidylinositol 3-kinase.
Interaction Experiment
Description: Angiotensin II-induced neural differentiation via angiotensin II type 2 (AT2) receptor-MMS2 cascade involving interaction between AT2 receptor-interacting protein and Src homology 2 domain-containing protein-tyrosine phosphatase 1.
Interaction Experiment
Description: Identification of a link between the SAMP repeats of adenomatous polyposis coli tumor suppressor and the Src homology 3 domain of DDEF.
Publication
First Author: Ursini-Siegel J
Year: 2008
Journal: EMBO J
Title: ShcA signalling is essential for tumour progression in mouse models of human breast cancer.
Volume: 27
Issue: 6
Pages: 910-20
Publication
First Author: Annerén C
Year: 2002
Journal: J Endocrinol
Title: Dual role of the tyrosine kinase GTK and the adaptor protein SHB in beta-cell growth: enhanced beta-cell replication after 60% pancreatectomy and increased sensitivity to streptozotocin.
Volume: 172
Issue: 1
Pages: 145-53
Publication
First Author: Sohn HW
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Fluorescence resonance energy transfer in living cells reveals dynamic membrane changes in the initiation of B cell signaling.
Volume: 103
Issue: 21
Pages: 8143-8
Publication
First Author: Bishop JL
Year: 2014
Journal: Mucosal Immunol
Title: Lyn activity protects mice from DSS colitis and regulates the production of IL-22 from innate lymphoid cells.
Volume: 7
Issue: 2
Pages: 405-16
Publication
First Author: Liu J
Year: 2005
Journal: Blood
Title: Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an alphaIIbbeta3- and aggregation-independent manner.
Volume: 106
Issue: 8
Pages: 2750-6
Protein
Organism: Mus musculus/domesticus
Length: 457  
Fragment?: false
Publication
First Author: Peikert K
Year: 2021
Journal: Acta Neuropathol Commun
Title: Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis.
Volume: 9
Issue: 1
Pages: 81
Publication
First Author: Gardai S
Year: 2002
Journal: J Biol Chem
Title: Activation of SHIP by NADPH oxidase-stimulated Lyn leads to enhanced apoptosis in neutrophils.
Volume: 277
Issue: 7
Pages: 5236-46
Publication
First Author: Meade J
Year: 2002
Journal: Eur J Immunol
Title: The tyrosine kinase Lyn is required for B cell development beyond the T1 stage in the spleen: rescue by over-expression of Bcl-2.
Volume: 32
Issue: 4
Pages: 1029-34
Publication
First Author: Urtz N
Year: 2004
Journal: Mol Cell Biol
Title: Early activation of sphingosine kinase in mast cells and recruitment to FcepsilonRI are mediated by its interaction with Lyn kinase.
Volume: 24
Issue: 19
Pages: 8765-77
Publication
First Author: Alvarez-Errico D
Year: 2010
Journal: J Immunol
Title: Functional analysis of Lyn kinase A and B isoforms reveals redundant and distinct roles in Fc epsilon RI-dependent mast cell activation.
Volume: 184
Issue: 9
Pages: 5000-8
Publication
First Author: Tezuka T
Year: 1996
Journal: J Exp Med
Title: Physical and functional association of the cbl protooncogen product with an src-family protein tyrosine kinase, p53/56lyn, in the B cell antigen receptor-mediated signaling.
Volume: 183
Issue: 2
Pages: 675-80
Genotype
Symbol: Lyn/Lyn Mpl/Mpl
Background: B6.129S1-Mpl
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Li X
Year: 2016
Journal: PLoS Pathog
Title: Lyn Delivers Bacteria to Lysosomes for Eradication through TLR2-Initiated Autophagy Related Phagocytosis.
Volume: 12
Issue: 1
Pages: e1005363
Publication
First Author: Corcoran LM
Year: 1999
Journal: J Immunol Methods
Title: Generation of B lymphoma cell lines from knockout mice by transformation in vivo with an Emu-myc transgene.
Volume: 228
Issue: 1-2
Pages: 131-8
Publication
First Author: Kennedy DJ
Year: 2011
Journal: Cardiovasc Res
Title: A CD36-dependent pathway enhances macrophage and adipose tissue inflammation and impairs insulin signalling.
Volume: 89
Issue: 3
Pages: 604-13
Publication
First Author: Triaca V
Year: 2016
Journal: Aging Cell
Title: NGF controls APP cleavage by downregulating APP phosphorylation at Thr668: relevance for Alzheimer's disease.
Volume: 15
Issue: 4
Pages: 661-72
Publication
First Author: Tachibana K
Year: 2005
Journal: Mol Cell Biol
Title: Selective role of a distinct tyrosine residue on Tie2 in heart development and early hematopoiesis.
Volume: 25
Issue: 11
Pages: 4693-702
Publication  
First Author: Ahn R
Year: 2017
Journal: Nat Commun
Title: The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression.
Volume: 8
Pages: 14638
Publication
First Author: Ferrante AW Jr
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Shark, a Src homology 2, ankyrin repeat, tyrosine kinase, is expressed on the apical surfaces of ectodermal epithelia.
Volume: 92
Issue: 6
Pages: 1911-5
Publication
First Author: Wang G
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Solution structure and peptide binding studies of the C-terminal src homology 3-like domain of the diphtheria toxin repressor protein.
Volume: 96
Issue: 11
Pages: 6119-24
Publication
First Author: Gupta D
Year: 1995
Journal: J Immunol
Title: Peptidoglycan induces transcription and secretion of TNF-alpha and activation of lyn, extracellular signal-regulated kinase, and rsk signal transduction proteins in mouse macrophages.
Volume: 155
Issue: 5
Pages: 2620-30
Publication
First Author: Liu J
Year: 2006
Journal: Blood
Title: Bruton tyrosine kinase is essential for botrocetin/VWF-induced signaling and GPIb-dependent thrombus formation in vivo.
Volume: 108
Issue: 8
Pages: 2596-603
Publication
First Author: Dasu T
Year: 2009
Journal: Mol Immunol
Title: CD19 signaling is impaired in murine peritoneal and splenic B-1 B lymphocytes.
Volume: 46
Issue: 13
Pages: 2655-65