|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 2901 to 3000 out of 4701 for Bcl2

0.025s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Strain
Attribute String: mutant strain, transgenic
Publication
First Author: Strasser A
Year: 1993
Journal: Oncogene
Title: E mu-bcl-2 transgene facilitates spontaneous transformation of early pre-B and immunoglobulin-secreting cells but not T cells.
Volume: 8
Issue: 1
Pages: 1-9
Publication
First Author: Smith KG
Year: 1994
Journal: Immunity
Title: Bcl-2 increases memory B cell recruitment but does not perturb selection in germinal centers.
Volume: 1
Issue: 9
Pages: 803-13
Publication
First Author: Grünewald J
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Mechanistic studies of the immunochemical termination of self-tolerance with unnatural amino acids.
Volume: 106
Issue: 11
Pages: 4337-42
Publication
First Author: Iwata A
Year: 2003
Journal: J Immunol
Title: Over-expression of Bcl-2 provides protection in septic mice by a trans effect.
Volume: 171
Issue: 6
Pages: 3136-41
Allele
Name: transgene insertion 1, Gerald W Dorn II
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
Genotype
Symbol: Tg(BCL2)1Tsk/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(BCL2)22Wehi/?
Background: involves: C57BL/6JWehi * SJL/JWehi
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(BCL2)36Wehi/?
Background: involves: C57BL/6JWehi * SJL/JWehi
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(BCL2)25Wehi/?
Background: involves: C57BL/6JWehi * SJL/JWehi
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Vav-BCL2)69Jad/?
Background: involves: C57BL/6J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(BCL2)22Wehi/?
Background: involves: C57BL/6J * C57BL/6JWehi
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(BCL2)36Wehi/?
Background: B6.Cg-Tg(BCL2)36Wehi/J
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Jena N
Year: 1997
Journal: Exp Cell Res
Title: BMP7 null mutation in mice: developmental defects in skeleton, kidney, and eye.
Volume: 230
Issue: 1
Pages: 28-37
Publication
First Author: Egle A
Year: 2004
Journal: Blood
Title: VavP-Bcl2 transgenic mice develop follicular lymphoma preceded by germinal center hyperplasia.
Volume: 103
Issue: 6
Pages: 2276-83
Publication
First Author: Le Beau MM
Year: 2002
Journal: Blood
Title: Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice parallel human acute promyelocytic leukemia.
Volume: 99
Issue: 8
Pages: 2985-91
Publication
First Author: Smits C
Year: 2008
Journal: Structure
Title: Structural plasticity underpins promiscuous binding of the prosurvival protein A1.
Volume: 16
Issue: 5
Pages: 818-29
Publication
First Author: Oganesyan G
Year: 2008
Journal: J Biol Chem
Title: IRF3-dependent type I interferon response in B cells regulates CpG-mediated antibody production.
Volume: 283
Issue: 2
Pages: 802-8
Publication
First Author: Wilson AM
Year: 2013
Journal: J Neurosci
Title: ASPP1/2 regulate p53-dependent death of retinal ganglion cells through PUMA and Fas/CD95 activation in vivo.
Volume: 33
Issue: 5
Pages: 2205-16
Publication
First Author: Kane M
Year: 2011
Journal: Immunity
Title: Innate immune sensing of retroviral infection via Toll-like receptor 7 occurs upon viral entry.
Volume: 35
Issue: 1
Pages: 135-45
Publication
First Author: Rothfuchs AG
Year: 2006
Journal: J Immunol
Title: STAT1 regulates IFN-alpha beta- and IFN-gamma-dependent control of infection with Chlamydia pneumoniae by nonhemopoietic cells.
Volume: 176
Issue: 11
Pages: 6982-90
Publication
First Author: Molle C
Year: 2010
Journal: J Immunol
Title: Critical role of the IFN-stimulated gene factor 3 complex in TLR-mediated IL-27p28 gene expression revealing a two-step activation process.
Volume: 184
Issue: 4
Pages: 1784-92
Publication
First Author: Chiang E
Year: 2006
Journal: J Immunol
Title: Cutting edge: apoptosis-regulating signal kinase 1 is required for reactive oxygen species-mediated activation of IFN regulatory factor 3 by lipopolysaccharide.
Volume: 176
Issue: 10
Pages: 5720-4
Publication
First Author: Jaillon S
Year: 2014
Journal: Immunity
Title: The humoral pattern recognition molecule PTX3 is a key component of innate immunity against urinary tract infection.
Volume: 40
Issue: 4
Pages: 621-32
Publication
First Author: Nistér M
Year: 2005
Journal: Oncogene
Title: p53 must be competent for transcriptional regulation to suppress tumor formation.
Volume: 24
Issue: 22
Pages: 3563-73
Publication
First Author: Shen H
Year: 2008
Journal: J Immunol
Title: Dual signaling of MyD88 and TRIF is critical for maximal TLR4-induced dendritic cell maturation.
Volume: 181
Issue: 3
Pages: 1849-58
Publication
First Author: Yadav M
Year: 2010
Journal: PLoS Pathog
Title: Inhibition of TIR domain signaling by TcpC: MyD88-dependent and independent effects on Escherichia coli virulence.
Volume: 6
Issue: 9
Pages: e1001120
Publication
First Author: Yanai H
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression.
Volume: 104
Issue: 9
Pages: 3402-7
Publication
First Author: Murakami S
Year: 2018
Journal: J Biochem
Title: Nucleomethylin deficiency impairs embryonic erythropoiesis.
Volume: 163
Issue: 5
Pages: 413-423
Publication
First Author: Ferdous A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Nkx2-5 transactivates the Ets-related protein 71 gene and specifies an endothelial/endocardial fate in the developing embryo.
Volume: 106
Issue: 3
Pages: 814-9
Publication
First Author: Li W
Year: 2014
Journal: J Virol
Title: IRF7-dependent type I interferon production induces lethal immune-mediated disease in STAT1 knockout mice infected with lymphocytic choriomeningitis virus.
Volume: 88
Issue: 13
Pages: 7578-88
Publication
First Author: Siegfried A
Year: 2013
Journal: J Immunol
Title: IFIT2 is an effector protein of type I IFN-mediated amplification of lipopolysaccharide (LPS)-induced TNF-α secretion and LPS-induced endotoxin shock.
Volume: 191
Issue: 7
Pages: 3913-21
Publication
First Author: Tsushima K
Year: 2011
Journal: FASEB J
Title: IRF3 regulates cardiac fibrosis but not hypertrophy in mice during angiotensin II-induced hypertension.
Volume: 25
Issue: 5
Pages: 1531-43
Publication
First Author: Guo B
Year: 2008
Journal: J Clin Invest
Title: The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice.
Volume: 118
Issue: 5
Pages: 1680-90
Publication
First Author: Proenca-Modena JL
Year: 2015
Journal: J Virol
Title: Interferon-Regulatory Factor 5-Dependent Signaling Restricts Orthobunyavirus Dissemination to the Central Nervous System.
Volume: 90
Issue: 1
Pages: 189-205
Publication
First Author: Kaileh M
Year: 2016
Journal: PLoS One
Title: mTOR-Dependent and Independent Survival Signaling by PI3K in B Lymphocytes.
Volume: 11
Issue: 1
Pages: e0146955
Publication
First Author: Keck S
Year: 2011
Journal: J Immunol
Title: Absence of TRIF signaling in lipopolysaccharide-stimulated murine mast cells.
Volume: 186
Issue: 9
Pages: 5478-88
Publication
First Author: Gu Y
Year: 2015
Journal: Mol Reprod Dev
Title: Deficiency of monoclonal non-specific suppressor factor beta (MNSFB) promotes pregnancy loss in mice.
Volume: 82
Issue: 6
Pages: 475-88
Publication
First Author: Iskandar K
Year: 2010
Journal: Am J Physiol Endocrinol Metab
Title: PDK-1/FoxO1 pathway in POMC neurons regulates Pomc expression and food intake.
Volume: 298
Issue: 4
Pages: E787-98
Publication
First Author: Inta I
Year: 2006
Journal: J Neurosci
Title: Bim and Noxa are candidates to mediate the deleterious effect of the NF-kappa B subunit RelA in cerebral ischemia.
Volume: 26
Issue: 50
Pages: 12896-903
Publication
First Author: Miller JC
Year: 2010
Journal: Infect Immun
Title: The Lyme disease spirochete Borrelia burgdorferi utilizes multiple ligands, including RNA, for interferon regulatory factor 3-dependent induction of type I interferon-responsive genes.
Volume: 78
Issue: 7
Pages: 3144-53
Publication
First Author: Oshiumi H
Year: 2011
Journal: J Immunol
Title: The TLR3/TICAM-1 pathway is mandatory for innate immune responses to poliovirus infection.
Volume: 187
Issue: 10
Pages: 5320-7
Publication
First Author: Ouyang X
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Cooperation between MyD88 and TRIF pathways in TLR synergy via IRF5 activation.
Volume: 354
Issue: 4
Pages: 1045-51
Publication
First Author: Rudd PA
Year: 2012
Journal: J Virol
Title: Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shock.
Volume: 86
Issue: 18
Pages: 9888-98
Publication
First Author: Takaki H
Year: 2013
Journal: J Immunol
Title: The MyD88 pathway in plasmacytoid and CD4+ dendritic cells primarily triggers type I IFN production against measles virus in a mouse infection model.
Volume: 191
Issue: 9
Pages: 4740-7
Publication
First Author: Schilte C
Year: 2012
Journal: J Immunol
Title: Cutting edge: independent roles for IRF-3 and IRF-7 in hematopoietic and nonhematopoietic cells during host response to Chikungunya infection.
Volume: 188
Issue: 7
Pages: 2967-71
Publication
First Author: Beauchamp MC
Year: 2019
Journal: PLoS One
Title: Loss of function mutation of Eftud2, the gene responsible for mandibulofacial dysostosis with microcephaly (MFDM), leads to pre-implantation arrest in mouse.
Volume: 14
Issue: 7
Pages: e0219280
Publication
First Author: Lehnertz B
Year: 2011
Journal: Mol Cell
Title: p53-dependent transcription and tumor suppression are not affected in Set7/9-deficient mice.
Volume: 43
Issue: 4
Pages: 673-80
Publication
First Author: Lam AR
Year: 2014
Journal: Cancer Res
Title: RAE1 ligands for the NKG2D receptor are regulated by STING-dependent DNA sensor pathways in lymphoma.
Volume: 74
Issue: 8
Pages: 2193-2203
Publication
First Author: Johnson J
Year: 2011
Journal: Mol Immunol
Title: A conventional protein kinase C inhibitor targeting IRF-3-dependent genes differentially regulates IL-12 family members.
Volume: 48
Issue: 12-13
Pages: 1484-93
Publication
First Author: Ebihara T
Year: 2010
Journal: J Exp Med
Title: Identification of a polyI:C-inducible membrane protein that participates in dendritic cell-mediated natural killer cell activation.
Volume: 207
Issue: 12
Pages: 2675-87
Publication
First Author: Takaki H
Year: 2014
Journal: Mol Immunol
Title: MAVS-dependent IRF3/7 bypass of interferon β-induction restricts the response to measles infection in CD150Tg mouse bone marrow-derived dendritic cells.
Volume: 57
Issue: 2
Pages: 100-10
Publication
First Author: Chen Y
Year: 2021
Journal: Cell Prolif
Title: Nbs1-mediated DNA damage repair pathway regulates haematopoietic stem cell development and embryonic haematopoiesis.
Volume: 54
Issue: 3
Pages: e12972
Publication
First Author: Wang D
Year: 2016
Journal: Nature
Title: Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode.
Volume: 538
Issue: 7623
Pages: 118-122
Publication
First Author: Shibata M
Year: 2002
Journal: J Cereb Blood Flow Metab
Title: Temporal profiles of the subcellular localization of Bim, a BH3-only protein, during middle cerebral artery occlusion in mice.
Volume: 22
Issue: 7
Pages: 810-20
Publication
First Author: Spokoini R
Year: 2010
Journal: Mol Endocrinol
Title: Glycogen synthase kinase-3 plays a central role in mediating glucocorticoid-induced apoptosis.
Volume: 24
Issue: 6
Pages: 1136-50
Publication
First Author: Bae KB
Year: 2011
Journal: Transgenic Res
Title: Overexpression of Jazf1 induces cardiac malformation through the upregulation of pro-apoptotic genes in mice.
Volume: 20
Issue: 5
Pages: 1019-31
Publication
First Author: Lu L
Year: 2015
Journal: J Bone Miner Res
Title: RECQL4 Regulates p53 Function In Vivo During Skeletogenesis.
Volume: 30
Issue: 6
Pages: 1077-89
Publication
First Author: Chen L
Year: 2005
Journal: Mol Cell
Title: Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function.
Volume: 17
Issue: 3
Pages: 393-403
Publication
First Author: Cunha DA
Year: 2012
Journal: Diabetes
Title: Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis.
Volume: 61
Issue: 11
Pages: 2763-75
Publication
First Author: Boudil A
Year: 2015
Journal: Nat Immunol
Title: IL-7 coordinates proliferation, differentiation and Tcra recombination during thymocyte β-selection.
Volume: 16
Issue: 4
Pages: 397-405
Publication
First Author: Hernández-Barranco A
Year: 2024
Journal: Cell Rep
Title: NGFR regulates stromal cell activation in germinal centers.
Volume: 43
Issue: 2
Pages: 113705
Publication
First Author: Kozaki T
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response.
Volume: 114
Issue: 10
Pages: 2681-2686
Publication    
First Author: Hirano KI
Year: 2021
Journal: Elife
Title: LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice.
Volume: 10
Publication
First Author: Zhang J
Year: 2015
Journal: Nat Med
Title: Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis.
Volume: 21
Issue: 10
Pages: 1190-8
Publication
First Author: Wu R
Year: 2023
Journal: Nat Commun
Title: Genetically prolonged beige fat in male mice confers long-lasting metabolic health.
Volume: 14
Issue: 1
Pages: 2731
Strain
Attribute String: transgenic, targeted mutation, mutant strain, congenic
Genotype
Symbol: Bcl2l11/Bcl2l11<+> Pten/Pten<+> Tg(CD2-icre)4Kio/?
Background: involves: 129S1/Sv * 129S4/SvJae * C57BL/10 * CBA/Ca
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bcl2l11/Bcl2l11 Dicer1/Dicer1 Cd79a/Cd79a<+>
Background: involves: 129S1/Sv * BALB/c
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bcl2l11/Bcl2l11 Dicer1/Dicer1 Aicda/Aicda<+>
Background: involves: 129S1/Sv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Atmin/Atmin Bcl2l11/Bcl2l11 Cd79a/Cd79a<+>
Background: involves: 129S1/Sv * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Atmin/Atmin Bcl2l11/Bcl2l11 Cd79a/Cd79a<+> Tg(IghMyc)22Bri/?
Background: B6.Cg-Bcl2l11 Cd79a Atmin Tg(IghMyc)22Bri
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bcl2l11/Bcl2l11<+> Morrbid/Morrbid<+>
Background: C57BL/6N-Bcl2l11 Morrbid /+ +
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bcl2l11/Bcl2l11<+> Morrbid<+>/Morrbid
Background: C57BL/6N-Bcl2l11 +/+ Morrbid
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bcl2l1/Bcl2l1 Bcl2l11/Bcl2l11 Hrk/Hrk
Background: involves: 129S1/Sv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bbc3/Bbc3 Cdkn1a/Cdkn1a Zmat3/Zmat3
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Cao X
Year: 2016
Journal: J Immunol
Title: Zbtb1 Safeguards Genome Integrity and Prevents p53-Mediated Apoptosis in Proliferating Lymphoid Progenitors.
Volume: 197
Issue: 4
Pages: 1199-211
Publication
First Author: Arakawa S
Year: 2017
Journal: Cell Death Differ
Title: Role of Atg5-dependent cell death in the embryonic development of Bax/Bak double-knockout mice.
Volume: 24
Issue: 9
Pages: 1598-1608
Publication
First Author: Dolence JJ
Year: 2014
Journal: Exp Hematol
Title: Flt3 signaling regulates the proliferation, survival, and maintenance of multipotent hematopoietic progenitors that generate B cell precursors.
Volume: 42
Issue: 5
Pages: 380-393.e3
Publication
First Author: Tuzlak S
Year: 2018
Journal: FEBS J
Title: Differential effects of Vav-promoter-driven overexpression of BCLX and BFL1 on lymphocyte survival and B cell lymphomagenesis.
Volume: 285
Issue: 8
Pages: 1403-1418
Publication
First Author: Barisic D
Year: 2024
Journal: Cancer Cell
Title: ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis.
Volume: 42
Issue: 4
Pages: 583-604.e11
Publication
First Author: Kosan C
Year: 2010
Journal: Immunity
Title: Transcription factor miz-1 is required to regulate interleukin-7 receptor signaling at early commitment stages of B cell differentiation.
Volume: 33
Issue: 6
Pages: 917-28
Publication
First Author: Ottina E
Year: 2017
Journal: Nat Commun
Title: DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice.
Volume: 8
Issue: 1
Pages: 1028
Publication
First Author: Wang X
Year: 2011
Journal: J Exp Med
Title: Follicular dendritic cells help establish follicle identity and promote B cell retention in germinal centers.
Volume: 208
Issue: 12
Pages: 2497-510
Publication
First Author: Rolink AG
Year: 2000
Journal: J Exp Med
Title: Precursor B cell receptor-dependent B cell proliferation and differentiation does not require the bone marrow or fetal liver environment.
Volume: 191
Issue: 1
Pages: 23-32
Publication
First Author: Fry TJ
Year: 2001
Journal: Blood
Title: Interleukin-7 restores immunity in athymic T-cell-depleted hosts.
Volume: 97
Issue: 6
Pages: 1525-33
Allele
Name: BCL2-associated X protein; targeted mutation 1, Stanley J Korsmeyer
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: B cell leukemia/lymphoma 2; targeted mutation 1, Max-Planck-Institute for Neurobiology
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Publication
First Author: Coré N
Year: 2004
Journal: Oncogene
Title: Disruption of E2F signaling suppresses the INK4a-induced proliferative defect in M33-deficient mice.
Volume: 23
Issue: 46
Pages: 7660-8
Publication
First Author: Nakazato K
Year: 2007
Journal: J Immunol
Title: Enforced expression of Bcl-2 partially restores cell numbers but not functions of TCRgammadelta intestinal intraepithelial T lymphocytes in IL-15-deficient mice.
Volume: 178
Issue: 2
Pages: 757-64
Publication
First Author: Peacock JW
Year: 2009
Journal: Mol Cell Biol
Title: PTEN loss promotes mitochondrially dependent type II Fas-induced apoptosis via PEA-15.
Volume: 29
Issue: 5
Pages: 1222-34
Allele
Name: transgene insertion 2272, Peter Angel
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: transgenic, mutant stock
Strain
Attribute String: congenic, mutant strain, transgenic
Publication
First Author: Beurlet S
Year: 2013
Journal: Blood
Title: BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells.
Volume: 122
Issue: 16
Pages: 2864-76
Publication
First Author: Jaiswal S
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias.
Volume: 100
Issue: 17
Pages: 10002-7
Publication
First Author: Khattar M
Year: 2014
Journal: PLoS One
Title: Interleukin-21 is a critical regulator of CD4 and CD8 T cell survival during priming under Interleukin-2 deprivation conditions.
Volume: 9
Issue: 1
Pages: e85882
Publication
First Author: Gapud EJ
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation.
Volume: 108
Issue: 5
Pages: 2022-7
Allele
Name: RAB8A, member RAS oncogene family; targeted mutation 1, Akihiro Harada
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: transgene insertion, Walter and Eliza Hall Institute of Medical Research
Allele Type: Transgenic
Attribute String: Inserted expressed sequence