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Search results 2901 to 3000 out of 3295 for Kras

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Hits by Strain

Type Details Score
Allele
Tg(Krt19-KRAS*G12V)AAru | MGI:4839478
Name: transgene insertion A, Anil K Rustgi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(CMV-KRAS*G12V,-EGFP)#Mjar | MGI:5286106
Name: transgene insertion, MJ Arends
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence, Reporter
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Allele
Tg(tetO-Kras*G12D)#Rdp | MGI:5648530
Name: transgene insertion, Ronald DePinho
Allele Type: Transgenic
Attribute String: Conditional ready, Inducible, Inserted expressed sequence
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Strain
MGI:5649289 | 129S2.129(Cg)-Kras<tm4.1Bbd>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5649291 | B6J.129(FVB)-Kras<tm4.1Bbd>
Attribute String: targeted mutation, mutant strain, congenic
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Allele
Kras<em2Jqmn> | MGI:6718984
Name: Kirsten rat sarcoma viral oncogene homolog; endonuclease-mediated mutation 2, Patrick Jacquemin
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Kras<tm3.1Cmco> | MGI:7432935
Name: Kirsten rat sarcoma viral oncogene homolog; targeted mutation 3.1, Christopher M Counter
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, Null/knockout
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Allele
Kras<tm4.1Cmco> | MGI:7432936
Name: Kirsten rat sarcoma viral oncogene homolog; targeted mutation 4.1, Christopher M Counter
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Kras<tm7.1Cmco> | MGI:7432942
Name: Kirsten rat sarcoma viral oncogene homolog; targeted mutation 7.1, Christopher M Counter
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Col1a1<tm2(tetO-GFP/RNAi:Kras462)Ttam> | MGI:7610034
Name: collagen, type I, alpha 1; targeted mutation 2, Tuomas Tammela
Allele Type: Targeted
Attribute String: Inducible, Knockdown, Reporter, RMCE-ready
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Allele
Col1a1<tm3(tetO-GFP/RNAi:Kras247)Ttam> | MGI:7610035
Name: collagen, type I, alpha 1; targeted mutation 3, Tuomas Tammela
Allele Type: Targeted
Attribute String: Inducible, Knockdown, Reporter, RMCE-ready
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Strain
MGI:7657632 | C57BL/6J-Kras<tm1Cya> Sftpc<em2(cre/Esr1*)Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Kras/Kras
Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bhlha15/Bhlha15<+> Trp53/Trp53<+>
Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras
Background: either: 129 or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+>
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+>
Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6J * FVB/N
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras
Background: 129S2.129(Cg)-Kras
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras
Background: B6J.129(FVB)-Kras
Zygosity: hm
Has Mutant Allele: true
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Publication
28232723 | J:244933
 
First Author: Ju HQ
Year: 2017
Journal: Nat Commun
Title: Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma.
Volume: 8
Pages: 14437
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Publication
22318779 | J:189130
First Author: Rebocho AP
Year: 2011
Journal: Cancer Discov
Title: New insight puts CRAF in sight as a therapeutic target.
Volume: 1
Issue: 2
Pages: 98-9
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Publication
24402942 | J:209158
First Author: Russo M
Year: 2014
Journal: Cancer Discov
Title: Climbing RAS, the everest of oncogenes.
Volume: 4
Issue: 1
Pages: 19-21
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Publication
39395421 | J:358349
First Author: Ross JL
Year: 2024
Journal: Immunity
Title: Microglia and monocyte-derived macrophages drive progression of pediatric high-grade gliomas and are transcriptionally shaped by histone mutations.
Volume: 57
Issue: 11
Pages: 2669-2687.e6
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Publication
23708211 | J:199111
First Author: Guijarro MV
Year: 2013
Journal: Am J Pathol
Title: Dual Pten/Tp53 suppression promotes sarcoma progression by activating Notch signaling.
Volume: 182
Issue: 6
Pages: 2015-27
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Publication
24823640 | J:210591
First Author: Aytes A
Year: 2014
Journal: Cancer Cell
Title: Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy.
Volume: 25
Issue: 5
Pages: 638-651
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Publication
21754979 | J:174838
First Author: Fomchenko EI
Year: 2011
Journal: PLoS One
Title: Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression.
Volume: 6
Issue: 7
Pages: e20605
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Publication
32238882 | J:335346
First Author: Uka R
Year: 2020
Journal: Oncogene
Title: Temporal activation of WNT/β-catenin signaling is sufficient to inhibit SOX10 expression and block melanoma growth.
Volume: 39
Issue: 20
Pages: 4132-4154
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Publication
31685822 | J:281598
First Author: Sun Q
Year: 2019
Journal: Nat Commun
Title: A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease.
Volume: 10
Issue: 1
Pages: 5023
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Publication
26359368 | J:231492
First Author: Garcia-Rendueles ME
Year: 2015
Journal: Cancer Discov
Title: NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition.
Volume: 5
Issue: 11
Pages: 1178-93
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Publication
34788609 | J:321169
First Author: Taranda J
Year: 2021
Journal: Cell Rep
Title: Combined whole-organ imaging at single-cell resolution and immunohistochemical analysis of prostate cancer and its liver and brain metastases.
Volume: 37
Issue: 7
Pages: 110027
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Publication
30833574 | J:273261
First Author: Hoeman CM
Year: 2019
Journal: Nat Commun
Title: ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis.
Volume: 10
Issue: 1
Pages: 1023
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Publication
27346348 | J:238518
First Author: Benhamou D
Year: 2016
Journal: Cell Rep
Title: A c-Myc/miR17-92/Pten Axis Controls PI3K-Mediated Positive and Negative Selection in B Cell Development and Reconstitutes CD19 Deficiency.
Volume: 16
Issue: 2
Pages: 419-31
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Publication
30674530 | J:273224
First Author: Beckmann PJ
Year: 2019
Journal: Cancer Res
Title: Sleeping Beauty Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors.
Volume: 79
Issue: 5
Pages: 905-917
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Publication
23150596 | J:192348
First Author: Schutzman JL
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Sprouty genes function in suppression of prostate tumorigenesis.
Volume: 109
Issue: 49
Pages: 20023-8
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Publication
36131018 | J:335416
First Author: Karras P
Year: 2022
Journal: Nature
Title: A cellular hierarchy in melanoma uncouples growth and metastasis.
Volume: 610
Issue: 7930
Pages: 190-198
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Publication
17496901 | J:121901
First Author: Hernando E
Year: 2007
Journal: Nat Med
Title: The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas.
Volume: 13
Issue: 6
Pages: 748-53
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Publication
20933441 | J:165522
First Author: Sathaliyawala T
Year: 2010
Journal: Immunity
Title: Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling.
Volume: 33
Issue: 4
Pages: 597-606
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Publication
19487573 | J:149210
First Author: Huse JT
Year: 2009
Journal: Genes Dev
Title: The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo.
Volume: 23
Issue: 11
Pages: 1327-37
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Publication
37991903 | J:346587
First Author: Viala S
Year: 2024
Journal: Mol Biol Cell
Title: LGN loss randomizes spindle orientation and accelerates tumorigenesis in PTEN-deficient epidermis.
Volume: 35
Issue: 2
Pages: br5
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Publication
32686704 | J:298942
First Author: Tagliatela AC
Year: 2020
Journal: Sci Rep
Title: Coronin 1C inhibits melanoma metastasis through regulation of MT1-MMP-containing extracellular vesicle secretion.
Volume: 10
Issue: 1
Pages: 11958
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Publication
29180473 | J:256302
First Author: Brighton HE
Year: 2018
Journal: Cancer Res
Title: New Mechanisms of Resistance to MEK Inhibitors in Melanoma Revealed by Intravital Imaging.
Volume: 78
Issue: 2
Pages: 542-557
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Publication
33910229 | J:308740
First Author: Ren AA
Year: 2021
Journal: Nature
Title: PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism.
Volume: 594
Issue: 7862
Pages: 271-276
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Genotype
Genotype
Symbol: Pten/Pten Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/? Tg(Osr1-cre)4Mrt/?
Background: involves: 129P2/OlaHsd * 129S1/Sv * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hras/Hras Pten/Pten Tg(TPO-cre)1Shk/?
Background: involves: 129S1/Sv * 129S6/SvEvTac * FVB/NCr
Zygosity: cn
Has Mutant Allele: true
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Strain
MGI:5645343 | B6.129-Kras<tm1Bbd>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5499525 | B6.129-Kras<tm1Bbd>/Cnbc
Attribute String: congenic, mutant strain, targeted mutation
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Publication
20959488 | J:165771
First Author: Okumura T
Year: 2010
Journal: Cancer Res
Title: K-ras mutation targeted to gastric tissue progenitor cells results in chronic inflammation, an altered microenvironment, and progression to intraepithelial neoplasia.
Volume: 70
Issue: 21
Pages: 8435-45
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Publication
25149534 | J:310369
First Author: Zatula N
Year: 2014
Journal: Oncotarget
Title: The BCL9-2 proto-oncogene governs estrogen receptor alpha expression in breast tumorigenesis.
Volume: 5
Issue: 16
Pages: 6770-87
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Genotype
Genotype
Symbol: Kras/Kras
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Map2k1/Map2k1
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Gene
673 | BRAF
Type: gene
Organism: human
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Gene
3265 | HRAS
Type: gene
Organism: human
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Publication
12226664 | J:78818
First Author: Bardeesy N
Year: 2002
Journal: Nature
Title: Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation.
Volume: 419
Issue: 6903
Pages: 162-7
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Publication
32894216 | J:347527
   
First Author: Tremblay M
Year: 2020
Journal: Elife
Title: Regulation of stem/progenitor cell maintenance by BMP5 in prostate homeostasis and cancer initiation.
Volume: 9
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Publication
19282848 | J:151023
First Author: Dankort D
Year: 2009
Journal: Nat Genet
Title: Braf(V600E) cooperates with Pten loss to induce metastatic melanoma.
Volume: 41
Issue: 5
Pages: 544-52
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Publication
22342906 | J:183946
First Author: Bloomekatz J
Year: 2012
Journal: Dev Biol
Title: Pten regulates collective cell migration during specification of the anterior-posterior axis of the mouse embryo.
Volume: 364
Issue: 2
Pages: 192-201
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Publication
23056544 | J:192099
First Author: Helmy K
Year: 2012
Journal: PLoS One
Title: Identification of global alteration of translational regulation in glioma in vivo.
Volume: 7
Issue: 10
Pages: e46965
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Publication
21267448 | J:208757
First Author: Pitter KL
Year: 2011
Journal: PLoS One
Title: Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma.
Volume: 6
Issue: 1
Pages: e14545
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Publication
33020472 | J:298638
First Author: De Boeck A
Year: 2020
Journal: Nat Commun
Title: Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression.
Volume: 11
Issue: 1
Pages: 4997
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Publication
32639068 | J:297579
First Author: Chen Z
Year: 2020
Journal: Glia
Title: Genetic driver mutations introduced in identical cell-of-origin in murine glioblastoma reveal distinct immune landscapes but similar response to checkpoint blockade.
Volume: 68
Issue: 10
Pages: 2148-2166
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Publication
33300045 | J:354474
First Author: Ross JL
Year: 2021
Journal: Brain
Title: Platelet-derived growth factor beta is a potent inflammatory driver in paediatric high-grade glioma.
Volume: 144
Issue: 1
Pages: 53-69
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Publication
28836293 | J:252858
First Author: Herting CJ
Year: 2017
Journal: Glia
Title: Genetic driver mutations define the expression signature and microenvironmental composition of high-grade gliomas.
Volume: 65
Issue: 12
Pages: 1914-1926
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Publication
27199435 | J:231882
First Author: Quail DF
Year: 2016
Journal: Science
Title: The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas.
Volume: 352
Issue: 6288
Pages: aad3018
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Publication
38416830 | J:345596
First Author: Yang F
Year: 2024
Journal: Sci Adv
Title: An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma.
Volume: 10
Issue: 9
Pages: eadj4678
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Publication
37733448 | J:342600
 
First Author: Chen Z
Year: 2023
Journal: J Clin Invest
Title: A paracrine circuit of IL-1β/IL-1R1 between myeloid and tumor cells drives genotype-dependent glioblastoma progression.
Volume: 133
Issue: 22
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Publication
28235764 | J:242079
First Author: Chen Z
Year: 2017
Journal: Cancer Res
Title: Cellular and Molecular Identity of Tumor-Associated Macrophages in Glioblastoma.
Volume: 77
Issue: 9
Pages: 2266-2278
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Publication
31825829 | J:301999
First Author: Buonfiglioli A
Year: 2019
Journal: Cell Rep
Title: let-7 MicroRNAs Regulate Microglial Function and Suppress Glioma Growth through Toll-Like Receptor 7.
Volume: 29
Issue: 11
Pages: 3460-3471.e7
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Publication
25829425 | J:225619
First Author: Nowak DG
Year: 2015
Journal: Cancer Discov
Title: MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2.
Volume: 5
Issue: 6
Pages: 636-51
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Publication
34099734 | J:307910
First Author: Brady NJ
Year: 2021
Journal: Nat Commun
Title: Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer.
Volume: 12
Issue: 1
Pages: 3372
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Publication
27341128 | J:240369
First Author: Das SK
Year: 2016
Journal: Oncotarget
Title: Knockout of MDA-9/Syntenin (SDCBP) expression in the microenvironment dampens tumor-supporting inflammation and inhibits melanoma metastasis.
Volume: 7
Issue: 30
Pages: 46848-46861
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Publication
37567175 | J:339309
First Author: Chessa TAM
Year: 2023
Journal: Mol Cell
Title: PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate.
Volume: 83
Issue: 16
Pages: 2991-3009.e13
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Publication
25164012 | J:216695
First Author: Palmer CJ
Year: 2014
Journal: Cancer Res
Title: Zfx facilitates tumorigenesis caused by activation of the Hedgehog pathway.
Volume: 74
Issue: 20
Pages: 5914-24
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Publication
32868382 | J:298565
First Author: Li G
Year: 2020
Journal: Cancer Res
Title: KDM5B Is Essential for the Hyperactivation of PI3K/AKT Signaling in Prostate Tumorigenesis.
Volume: 80
Issue: 21
Pages: 4633-4643
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Publication
27536883 | J:243736
First Author: Gao D
Year: 2016
Journal: PLoS One
Title: A Tmprss2-CreERT2 Knock-In Mouse Model for Cancer Genetic Studies on Prostate and Colon.
Volume: 11
Issue: 8
Pages: e0161084
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pten/Pten Rb1/Rb1 Tg(Pbsn-cre)4Prb/?
Background: involves: 129 * 129S1/Sv * 129S6/SvEvTac * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pten/Pten Rb1/Rb1<+> Tg(Pbsn-cre)4Prb/?
Background: involves: 129 * 129S1/Sv * 129S6/SvEvTac * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pten/Pten Rb1/Rb1 Tg(Pbsn-cre)4Prb/?
Background: involves: 129 * 129S1/Sv * 129S6/SvEvTac * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Publication
19878864 | J:153950
First Author: Morris JP 4th
Year: 2009
Journal: Cancer Cell
Title: It's a free for all--insulin-positive cells join the group of potential progenitors for pancreatic ductal adenocarcinoma.
Volume: 16
Issue: 5
Pages: 359-61
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Publication
22624710 | J:189302
First Author: Barbacid M
Year: 2012
Journal: Cancer Cell
Title: Opening a new GATAway for treating KRAS-driven lung tumors.
Volume: 21
Issue: 5
Pages: 598-600
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Publication
22975369 | J:192909
First Author: Perera RM
Year: 2012
Journal: Cancer Cell
Title: Ready, set, go: the EGF receptor at the pancreatic cancer starting line.
Volume: 22
Issue: 3
Pages: 281-2
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Publication
24823632 | J:210594
First Author: Vonderheide RH
Year: 2014
Journal: Cancer Cell
Title: Tumor-promoting inflammatory networks in pancreatic neoplasia: another reason to loathe Kras.
Volume: 25
Issue: 5
Pages: 553-4
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Publication
17297472 | J:122904
First Author: Luo F
Year: 2007
Journal: Oncogene
Title: Conditional expression of mutated K-ras accelerates intestinal tumorigenesis in Msh2-deficient mice.
Volume: 26
Issue: 30
Pages: 4415-27
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Strain
MGI:7607866 | STOCK Kras<tm3.1Cmco>/Unc
Attribute String: mutant stock, targeted mutation
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Strain
MGI:7607867 | STOCK Kras<tm4.1Cmco>/Unc
Attribute String: mutant stock, targeted mutation
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Strain
MGI:7607868 | STOCK Kras<tm7.1Cmco>/Unc
Attribute String: mutant stock, targeted mutation
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Genotype
Genotype
Symbol: Fntb/Fntb Kras/Kras<+> Polr2a/Polr2a
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Tg(CMV-cre)1Cgn/?
Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Eef1a1/Eef1a1<+> Tg(Hsp70-1-cre)1Arge/?
Background: involves: 129S1/Sv * C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Eef1a1/Eef1a1<+> Wap/Wap<+>
Background: involves: 129S1/Sv
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Eef1a1/Eef1a1<+> Igf1r/Igf1r<+> Wap/Wap<+>
Background: involves: 129S1/Sv
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Eef1a1/Eef1a1<+> Igf1r/Igf1r Wap/Wap<+>
Background: involves: 129S1/Sv
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Polr2a/Polr2a
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras Polr2a/Polr2a
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdk4/Cdk4 Kras/Kras Polr2a/Polr2a
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Trp53/Trp53 Gt(ROSA)26Sor/Gt(ROSA)26Sor
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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•
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Genotype
Genotype
Symbol: Kras/Kras<+> Trp53/Trp53
Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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•
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Genotype
Genotype
Symbol: Kras/Kras<+> Mapk3/Mapk3
Background: involves: 129/Sv * 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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•
•
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•
Genotype
Genotype
Symbol: Kras/Kras<+> Mapk1/Mapk1
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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•
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•
Genotype
Genotype
Symbol: Kras/Kras<+> Map2k2/Map2k2
Background: involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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