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Search results 2901 to 3000 out of 3210 for Lepr

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Type Details Score
Publication
30181160 | J:265890
First Author: Jiao Y
Year: 2018
Journal: Diabetes
Title: SRY-Box Containing Gene 4 Promotes Liver Steatosis by Upregulation of SREBP-1c.
Volume: 67
Issue: 11
Pages: 2227-2238
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31553910 | J:347141
First Author: Li Q
Year: 2019
Journal: Cell Rep
Title: The Protein Phosphatase 1 Complex Is a Direct Target of AKT that Links Insulin Signaling to Hepatic Glycogen Deposition.
Volume: 28
Issue: 13
Pages: 3406-3422.e7
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Publication
23991045 | J:205959
First Author: Hutchinson KR
Year: 2013
Journal: PLoS One
Title: Cardiac fibroblast-dependent extracellular matrix accumulation is associated with diastolic stiffness in type 2 diabetes.
Volume: 8
Issue: 8
Pages: e72080
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Publication
29028997 | J:251906
First Author: Kyohara M
Year: 2017
Journal: Endocrinology
Title: Serum Quantitative Proteomic Analysis Reveals Soluble EGFR To Be a Marker of Insulin Resistance in Male Mice and Humans.
Volume: 158
Issue: 12
Pages: 4152-4164
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Publication
37591884 | J:357550
First Author: Shi MY
Year: 2023
Journal: Nat Commun
Title: p21-activated kinase 4 suppresses fatty acid β-oxidation and ketogenesis by phosphorylating NCoR1.
Volume: 14
Issue: 1
Pages: 4987
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Publication
28843785 | J:251920
First Author: Fan Z
Year: 2017
Journal: Biochim Biophys Acta
Title: HIF-1α coordinates epigenetic activation of SIAH1 in hepatocytes in response to nutritional stress.
Volume: 1860
Issue: 10
Pages: 1037-1046
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Publication
25651564 | J:280116
First Author: Su H
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: MAD2B contributes to podocyte injury of diabetic nephropathy via inducing cyclin B1 and Skp2 accumulation.
Volume: 308
Issue: 7
Pages: F728-36
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Publication
30102256 | J:266192
First Author: Wu H
Year: 2018
Journal: J Clin Invest
Title: Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes.
Volume: 128
Issue: 9
Pages: 4025-4043
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Publication
15685168 | J:96047
First Author: Uchida T
Year: 2005
Journal: Nat Med
Title: Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice.
Volume: 11
Issue: 2
Pages: 175-82
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Publication
29526568 | J:321145
 
First Author: Giralt A
Year: 2018
Journal: Mol Metab
Title: E2F1 promotes hepatic gluconeogenesis and contributes to hyperglycemia during diabetes.
Volume: 11
Pages: 104-112
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Publication
37739218 | J:357793
First Author: Kwon J
Year: 2023
Journal: Biochim Biophys Acta Gene Regul Mech
Title: Inflammation-induced nitric oxide suppresses PPARα expression and function via downregulation of Sp1 transcriptional activity in adipocytes.
Volume: 1866
Issue: 4
Pages: 194987
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Publication
33667344 | J:303708
First Author: McKimpson WM
Year: 2021
Journal: Dev Cell
Title: Conversion of the death inhibitor ARC to a killer activates pancreatic β cell death in diabetes.
Volume: 56
Issue: 6
Pages: 747-760.e6
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Publication
28165007 | J:243820
 
First Author: Luk CT
Year: 2017
Journal: Nat Commun
Title: FAK signalling controls insulin sensitivity through regulation of adipocyte survival.
Volume: 8
Pages: 14360
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Publication
34672983 | J:315147
First Author: Kamm GB
Year: 2021
Journal: Neuron
Title: A synaptic temperature sensor for body cooling.
Volume: 109
Issue: 20
Pages: 3283-3297.e11
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16327801 | J:104468
First Author: Nakagawa Y
Year: 2006
Journal: Nat Med
Title: TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes.
Volume: 12
Issue: 1
Pages: 107-13
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24995979 | J:214637
First Author: Kong X
Year: 2014
Journal: Cell
Title: IRF4 is a key thermogenic transcriptional partner of PGC-1α.
Volume: 158
Issue: 1
Pages: 69-83
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Publication
27848995 | J:244116
 
First Author: Huang HM
Year: 2016
Journal: Sci Rep
Title: A novel ENU-induced ankyrin-1 mutation impairs parasite invasion and increases erythrocyte clearance during malaria infection in mice.
Volume: 6
Pages: 37197
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20713153 | J:170003
First Author: Campo GM
Year: 2010
Journal: Biochim Biophys Acta
Title: High-molecular weight hyaluronan reduced renal PKC activation in genetically diabetic mice.
Volume: 1802
Issue: 11
Pages: 1118-30
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Publication
35440636 | J:342225
First Author: Xia H
Year: 2022
Journal: Nat Commun
Title: Insulin action and resistance are dependent on a GSK3β-FBXW7-ERRα transcriptional axis.
Volume: 13
Issue: 1
Pages: 2105
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Publication
23881913 | J:202625
First Author: Tao R
Year: 2013
Journal: J Lipid Res
Title: Hepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6.
Volume: 54
Issue: 10
Pages: 2745-53
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Publication
26116826 | J:227036
 
First Author: Hirukawa H
Year: 2015
Journal: Mol Cell Endocrinol
Title: Combination of DPP-4 inhibitor and PPARγ agonist exerts protective effects on pancreatic β-cells in diabetic db/db mice through the augmentation of IRS-2 expression.
Volume: 413
Pages: 49-60
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Publication
25985365 | J:314874
First Author: Belgardt BF
Year: 2015
Journal: Nat Med
Title: The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes.
Volume: 21
Issue: 6
Pages: 619-27
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Publication
19834009 | J:170144
First Author: Li S
Year: 2009
Journal: Circ Res
Title: Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob/ob mice and reversal by a fish oil diet.
Volume: 105
Issue: 11
Pages: 1072-82
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1978328 | J:10819
First Author: Bahary N
Year: 1990
Journal: Proc Natl Acad Sci U S A
Title: Molecular mapping of the mouse db mutation.
Volume: 87
Issue: 21
Pages: 8642-6
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22140039 | J:182465
First Author: Su W
Year: 2012
Journal: Am J Physiol Heart Circ Physiol
Title: Altered clock gene expression and vascular smooth muscle diurnal contractile variations in type 2 diabetic db/db mice.
Volume: 302
Issue: 3
Pages: H621-33
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Publication
31042800 | J:276025
First Author: Luo Q
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: The Diurnal Rhythm of Insulin Receptor Substrate-1 (IRS-1) and Kir4.1 in Diabetes: Implications for a Clock Gene Bmal1.
Volume: 60
Issue: 6
Pages: 1928-1936
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Publication
18854155 | J:149873
First Author: Zhang X
Year: 2008
Journal: Cell
Title: Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity.
Volume: 135
Issue: 1
Pages: 61-73
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34475098 | J:321780
First Author: Xu Y
Year: 2021
Journal: Diabetes
Title: Hepatocytic Activating Transcription Factor 3 Protects Against Steatohepatitis via Hepatocyte Nuclear Factor 4α.
Volume: 70
Issue: 11
Pages: 2506-2517
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Publication
34010595 | J:321762
First Author: Liu TC
Year: 2021
Journal: Cell Host Microbe
Title: Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation.
Volume: 29
Issue: 6
Pages: 988-1001.e6
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Publication
36543979 | J:352483
First Author: Griess K
Year: 2023
Journal: Nat Cell Biol
Title: Sphingolipid subtypes differentially control proinsulin processing and systemic glucose homeostasis.
Volume: 25
Issue: 1
Pages: 20-29
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Publication
28604703 | J:304406
First Author: Worthmann A
Year: 2017
Journal: Nat Med
Title: Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis.
Volume: 23
Issue: 7
Pages: 839-849
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Publication
27053360 | J:235404
First Author: Zhao Y
Year: 2016
Journal: Cell Metab
Title: Sodium Intake Regulates Glucose Homeostasis through the PPARδ/Adiponectin-Mediated SGLT2 Pathway.
Volume: 23
Issue: 4
Pages: 699-711
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Publication
32726607 | J:296610
First Author: Tomita I
Year: 2020
Journal: Cell Metab
Title: SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition.
Volume: 32
Issue: 3
Pages: 404-419.e6
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Publication
19666843 | J:154218
First Author: Nuno DW
Year: 2009
Journal: Am J Physiol Heart Circ Physiol
Title: Sex-dependent differences in Rho activation contribute to contractile dysfunction in type 2 diabetic mice.
Volume: 297
Issue: 4
Pages: H1469-77
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Publication
16282354 | J:105139
First Author: Udagawa J
Year: 2006
Journal: Endocrinology
Title: The role of leptin in the development of the cerebral cortex in mouse embryos.
Volume: 147
Issue: 2
Pages: 647-58
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Publication
37949368 | J:355268
First Author: Huang Y
Year: 2024
Journal: J Lipid Res
Title: The role of KLF2 in regulating hepatic lipogenesis and blood cholesterol homeostasis via the SCAP/SREBP pathway.
Volume: 65
Issue: 1
Pages: 100472
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Publication
17084711 | J:129761
First Author: Schneider JG
Year: 2006
Journal: Cell Metab
Title: ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome.
Volume: 4
Issue: 5
Pages: 377-89
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Publication
19838201 | J:154295
First Author: Cheng Z
Year: 2009
Journal: Nat Med
Title: Foxo1 integrates insulin signaling with mitochondrial function in the liver.
Volume: 15
Issue: 11
Pages: 1307-11
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Publication
38093014 | J:349838
First Author: Nobs SP
Year: 2023
Journal: Nature
Title: Lung dendritic-cell metabolism underlies susceptibility to viral infection in diabetes.
Volume: 624
Issue: 7992
Pages: 645-652
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Publication
23663741 | J:199269
First Author: Lin Z
Year: 2013
Journal: Cell Metab
Title: Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice.
Volume: 17
Issue: 5
Pages: 779-89
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Publication
27213816 | J:239768
First Author: Scarlett JM
Year: 2016
Journal: Nat Med
Title: Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents.
Volume: 22
Issue: 7
Pages: 800-6
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Publication
36505926 | J:334321
First Author: Miyashita D
Year: 2022
Journal: iScience
Title: Protective effects of S100A8 on sepsis mortality: Links to sepsis risk in obesity and diabetes.
Volume: 25
Issue: 12
Pages: 105662
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Publication
26481668 | J:235829
First Author: Zhou Y
Year: 2015
Journal: Cell Metab
Title: Leptin Deficiency Shifts Mast Cells toward Anti-Inflammatory Actions and Protects Mice from Obesity and Diabetes by Polarizing M2 Macrophages.
Volume: 22
Issue: 6
Pages: 1045-58
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Publication
18562627 | J:138276
First Author: Park KW
Year: 2008
Journal: Mol Endocrinol
Title: Inhibitor of DNA binding 2 is a small molecule-inducible modulator of peroxisome proliferator-activated receptor-gamma expression and adipocyte differentiation.
Volume: 22
Issue: 9
Pages: 2038-48
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Publication
25537494 | J:219759
First Author: Chen S
Year: 2015
Journal: Am J Physiol Endocrinol Metab
Title: Increased GIP signaling induces adipose inflammation via a HIF-1α-dependent pathway and impairs insulin sensitivity in mice.
Volume: 308
Issue: 5
Pages: E414-25
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Publication
33951475 | J:307393
First Author: Gruber T
Year: 2021
Journal: Cell Metab
Title: Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension.
Volume: 33
Issue: 6
Pages: 1155-1170.e10
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Publication
28129327 | J:246824
First Author: Cataldo LR
Year: 2017
Journal: PLoS One
Title: Prolonged Activation of the Htr2b Serotonin Receptor Impairs Glucose Stimulated Insulin Secretion and Mitochondrial Function in MIN6 Cells.
Volume: 12
Issue: 1
Pages: e0170213
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Publication
23348573 | J:310932
First Author: Wu J
Year: 2013
Journal: Hepatology
Title: Thyroid hormone-responsive SPOT 14 homolog promotes hepatic lipogenesis, and its expression is regulated by liver X receptor α through a sterol regulatory element-binding protein 1c-dependent mechanism in mice.
Volume: 58
Issue: 2
Pages: 617-28
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Publication
18381283 | J:138581
First Author: Wolfrum C
Year: 2008
Journal: J Biol Chem
Title: Foxa2 activity increases plasma high density lipoprotein levels by regulating apolipoprotein M.
Volume: 283
Issue: 24
Pages: 16940-9
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Publication
19543271 | J:154956
First Author: Kato M
Year: 2009
Journal: Nat Cell Biol
Title: TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN.
Volume: 11
Issue: 7
Pages: 881-9
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Publication
35323110 | J:338604
   
First Author: Çakır I
Year: 2022
Journal: Elife
Title: Sulforaphane reduces obesity by reversing leptin resistance.
Volume: 11
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Publication
35029658 | J:321946
 
First Author: Takada N
Year: 2022
Journal: Development
Title: Galectin-3 promotes the adipogenic differentiation of PDGFRα+ cells and ectopic fat formation in regenerating muscle.
Volume: 149
Issue: 3
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Publication
24051374 | J:204007
First Author: Ravnskjaer K
Year: 2013
Journal: J Clin Invest
Title: Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects.
Volume: 123
Issue: 10
Pages: 4318-28
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Publication
24392081 | J:212216
First Author: Cho YR
Year: 2014
Journal: PLoS One
Title: Therapeutic effects of fenofibrate on diabetic peripheral neuropathy by improving endothelial and neural survival in db/db mice.
Volume: 9
Issue: 1
Pages: e83204
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Publication
29959129 | J:341461
First Author: Li Z
Year: 2018
Journal: Diabetes
Title: Inhibition of Epidermal Growth Factor Receptor Activation Is Associated With Improved Diabetic Nephropathy and Insulin Resistance in Type 2 Diabetes.
Volume: 67
Issue: 9
Pages: 1847-1857
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Publication
25157160 | J:216395
First Author: Li Z
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Ghrelin promotes hepatic lipogenesis by activation of mTOR-PPARγ signaling pathway.
Volume: 111
Issue: 36
Pages: 13163-8
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Publication
29434323 | J:263808
First Author: Kobayashi N
Year: 2018
Journal: Sci Rep
Title: CD44 variant inhibits insulin secretion in pancreatic β cells by attenuating LAT1-mediated amino acid uptake.
Volume: 8
Issue: 1
Pages: 2785
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Publication
28508871 | J:250405
 
First Author: Zhou M
Year: 2017
Journal: Nat Commun
Title: Non-cell-autonomous activation of IL-6/STAT3 signaling mediates FGF19-driven hepatocarcinogenesis.
Volume: 8
Pages: 15433
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12595588 | J:102264
First Author: Yamashita H
Year: 2003
Journal: Pediatr Res
Title: Effect of spontaneous gestational diabetes on fetal and postnatal hepatic insulin resistance in Lepr(db/+) mice.
Volume: 53
Issue: 3
Pages: 411-8
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Publication
32183843 | J:318044
First Author: Pelletier RM
Year: 2020
Journal: Reprod Biol Endocrinol
Title: Glucose, insulin, insulin receptor subunits α and β in normal and spontaneously diabetic and obese ob/ob and db/db infertile mouse testis and hypophysis.
Volume: 18
Issue: 1
Pages: 25
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Publication
19254698 | J:147384
First Author: Awazawa M
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Adiponectin suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/AMPK dependent pathway.
Volume: 382
Issue: 1
Pages: 51-6
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Publication
21700708 | J:175918
First Author: Tanioka T
Year: 2011
Journal: J Biol Chem
Title: Inducible nitric-oxide synthase and nitric oxide donor decrease insulin receptor substrate-2 protein expression by promoting proteasome-dependent degradation in pancreatic beta-cells: involvement of glycogen synthase kinase-3beta.
Volume: 286
Issue: 33
Pages: 29388-96
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20713358 | J:338157
First Author: Kato M
Year: 2010
Journal: J Biol Chem
Title: Post-transcriptional up-regulation of Tsc-22 by Ybx1, a target of miR-216a, mediates TGF-{beta}-induced collagen expression in kidney cells.
Volume: 285
Issue: 44
Pages: 34004-15
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27207656 | J:232782
First Author: Wang H
Year: 2016
Journal: Carcinogenesis
Title: Obesity promotes PhIP-induced small intestinal carcinogenesis in hCYP1A-db/db mice: involvement of mutations and DNA hypermethylation of Apc.
Volume: 37
Issue: 7
Pages: 723-730
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Publication
36001955 | J:344141
First Author: Wang Y
Year: 2022
Journal: Cell Rep
Title: Hepatocyte Rap1a contributes to obesity- and statin-associated hyperglycemia.
Volume: 40
Issue: 8
Pages: 111259
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Publication
22465219 | J:327866
First Author: Taguchi K
Year: 2012
Journal: Pharmacol Res
Title: Angiotensin II type 2 receptor-dependent increase in nitric oxide synthase activity in the endothelium of db/db mice is mediated via a MEK pathway.
Volume: 66
Issue: 1
Pages: 41-50
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22933112 | J:208491
First Author: Huang A
Year: 2012
Journal: Diabetes
Title: Altered MAPK signaling in progressive deterioration of endothelial function in diabetic mice.
Volume: 61
Issue: 12
Pages: 3181-8
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29088301 | J:247696
First Author: Vancura P
Year: 2017
Journal: PLoS One
Title: Gnaz couples the circadian and dopaminergic system to G protein-mediated signaling in mouse photoreceptors.
Volume: 12
Issue: 10
Pages: e0187411
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Publication
30121753 | J:317334
First Author: Nwadozi E
Year: 2019
Journal: Angiogenesis
Title: Leptin is a physiological regulator of skeletal muscle angiogenesis and is locally produced by PDGFRα and PDGFRβ expressing perivascular cells.
Volume: 22
Issue: 1
Pages: 103-115
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22896587 | J:212630
First Author: Sansbury BE
Year: 2012
Journal: Circ Res
Title: Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype.
Volume: 111
Issue: 9
Pages: 1176-89
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8177042 | J:18161
First Author: Nishina PM
Year: 1994
Journal: Metabolism
Title: Characterization of plasma lipids in genetically obese mice: the mutants obese, diabetes, fat, tubby, and lethal yellow.
Volume: 43
Issue: 5
Pages: 549-53
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26121233 | J:233065
First Author: Youn JY
Year: 2015
Journal: Mol Endocrinol
Title: Bone Morphogenic Protein 4 Mediates NOX1-Dependent eNOS Uncoupling, Endothelial Dysfunction, and COX2 Induction in Type 2 Diabetes Mellitus.
Volume: 29
Issue: 8
Pages: 1123-33
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Publication
21109192 | J:168117
First Author: Stienstra R
Year: 2010
Journal: Cell Metab
Title: The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity.
Volume: 12
Issue: 6
Pages: 593-605
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21459325 | J:172246
First Author: Awazawa M
Year: 2011
Journal: Cell Metab
Title: Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway.
Volume: 13
Issue: 4
Pages: 401-412
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Publication
37202506 | J:337759
First Author: Yang W
Year: 2023
Journal: Diabetologia
Title: Hepatic p38α MAPK controls gluconeogenesis via FOXO1 phosphorylation at S273 during glucagon signalling in mice.
Volume: 66
Issue: 7
Pages: 1322-1339
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Publication
37167965 | J:352924
First Author: Sun H
Year: 2023
Journal: Cell Metab
Title: Sustained remission of type 2 diabetes in rodents by centrally administered fibroblast growth factor 4.
Volume: 35
Issue: 6
Pages: 1022-1037.e6
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Publication
23884889 | J:208939
First Author: Mao J
Year: 2013
Journal: Diabetes
Title: Overnutrition stimulates intestinal epithelium proliferation through β-catenin signaling in obese mice.
Volume: 62
Issue: 11
Pages: 3736-46
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23801577 | J:208951
First Author: Shirakawa J
Year: 2013
Journal: Diabetes
Title: Glucokinase activation ameliorates ER stress-induced apoptosis in pancreatic β-cells.
Volume: 62
Issue: 10
Pages: 3448-58
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Publication
22969086 | J:192963
First Author: Zhang Y
Year: 2012
Journal: J Biol Chem
Title: A role for protein inhibitor of activated STAT1 (PIAS1) in lipogenic regulation through SUMOylation-independent suppression of liver X receptors.
Volume: 287
Issue: 45
Pages: 37973-85
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Publication
24608443 | J:229493
First Author: Liu R
Year: 2014
Journal: Diabetes
Title: Role of transcription factor acetylation in diabetic kidney disease.
Volume: 63
Issue: 7
Pages: 2440-53
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Publication
36050503 | J:333118
First Author: Zhou B
Year: 2022
Journal: Nat Metab
Title: Orosomucoid 2 maintains hepatic lipid homeostasis through suppression of de novo lipogenesis.
Volume: 4
Issue: 9
Pages: 1185-1201
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Publication
19219422 | J:148209
First Author: Kaddai V
Year: 2009
Journal: Diabetologia
Title: Involvement of TNF-alpha in abnormal adipocyte and muscle sortilin expression in obese mice and humans.
Volume: 52
Issue: 5
Pages: 932-40
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Publication
27870582 | J:248334
First Author: Hogan MF
Year: 2017
Journal: Endocrinology
Title: Markers of Islet Endothelial Dysfunction Occur in Male B6.BKS(D)-Leprdb/J Mice and May Contribute to Reduced Insulin Release.
Volume: 158
Issue: 2
Pages: 293-303
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Publication
29301787 | J:277053
First Author: Sudhahar V
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Akt2 (Protein Kinase B Beta) Stabilizes ATP7A, a Copper Transporter for Extracellular Superoxide Dismutase, in Vascular Smooth Muscle: Novel Mechanism to Limit Endothelial Dysfunction in Type 2 Diabetes Mellitus.
Volume: 38
Issue: 3
Pages: 529-541
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