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Search results 2901 to 3000 out of 3175 for Mapt

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Type Details Score
Publication
35719714 | J:351734
First Author: Hu W
Year: 2022
Journal: J Alzheimers Dis Rep
Title: Heightened Tameness and Accelerated Handling-Habituation in 3?Tg-AD Mice on a B6;129 Genetic Background.
Volume: 6
Issue: 1
Pages: 245-255
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Publication
31596896 | J:280799
First Author: Mu?oz-Cabrera JM
Year: 2019
Journal: PLoS One
Title: Bexarotene therapy ameliorates behavioral deficits and induces functional and molecular changes in very-old Triple Transgenic Mice model of Alzheimer?s disease.
Volume: 14
Issue: 10
Pages: e0223578
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Publication
24973121 | J:218072
First Author: Di Meco A
Year: 2014
Journal: Neurobiol Aging
Title: Zileuton restores memory impairments and reverses amyloid and tau pathology in aged Alzheimer's disease mice.
Volume: 35
Issue: 11
Pages: 2458-2464
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Publication
35853553 | J:351735
 
First Author: Diaz-Amarilla P
Year: 2022
Journal: Neurochem Int
Title: Isolation and characterization of neurotoxic astrocytes derived from adult triple transgenic Alzheimer's disease mice.
Volume: 159
Pages: 105403
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Publication
29068127 | J:351780
First Author: Lin KH
Year: 2018
Journal: Environ Toxicol
Title: The preventive effects of edible folic acid on cardiomyocyte apoptosis and survival in early onset triple-transgenic Alzheimer's disease model mice.
Volume: 33
Issue: 1
Pages: 83-92
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Publication
29204248 | J:351781
 
First Author: Nie L
Year: 2017
Journal: Oxid Med Cell Longev
Title: Ginsenoside Rg1 Ameliorates Behavioral Abnormalities and Modulates the Hippocampal Proteomic Change in Triple Transgenic Mice of Alzheimer's Disease.
Volume: 2017
Pages: 6473506
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Publication
29233183 | J:351782
First Author: Hwang KD
Year: 2017
Journal: Mol Brain
Title: Restoring synaptic plasticity and memory in mouse models of Alzheimer's disease by PKR inhibition.
Volume: 10
Issue: 1
Pages: 57
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Publication
35377002 | J:350410
First Author: Marcatti M
Year: 2022
Journal: Cell Mol Life Sci
Title: A?/tau oligomer interplay at human synapses supports shifting therapeutic targets for Alzheimer's disease.
Volume: 79
Issue: 4
Pages: 222
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Publication
31954826 | J:293128
 
First Author: Mendell AL
Year: 2020
Journal: Neuroscience
Title: Inhibition of 5? Reductase Impairs Cognitive Performance, Alters Dendritic Morphology and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice.
Volume: 429
Pages: 185-202
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Publication
30870531 | J:284854
First Author: De Chiara G
Year: 2019
Journal: PLoS Pathog
Title: Recurrent herpes simplex virus-1 infection induces hallmarks of neurodegeneration and cognitive deficits in mice.
Volume: 15
Issue: 3
Pages: e1007617
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Publication
20098691 | J:286160
First Author: Hasegawa T
Year: 2010
Journal: PLoS One
Title: Treatment of Alzheimer's disease with anti-homocysteic acid antibody in 3xTg-AD male mice.
Volume: 5
Issue: 1
Pages: e8593
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Publication
18045930 | J:127796
First Author: Carroll JC
Year: 2007
Journal: J Neurosci
Title: Progesterone and estrogen regulate Alzheimer-like neuropathology in female 3xTg-AD mice.
Volume: 27
Issue: 48
Pages: 13357-65
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Publication
25024345 | J:351730
First Author: O'Bryant SE
Year: 2014
Journal: J Alzheimers Dis
Title: Validation of a serum screen for Alzheimer's disease across assay platforms, species, and tissues.
Volume: 42
Issue: 4
Pages: 1325-35
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Publication
36610160 | J:351745
 
First Author: He Z
Year: 2023
Journal: Phytomedicine
Title: The protective effects of Esculentoside A through AMPK in the triple transgenic mouse model of Alzheimer's disease.
Volume: 109
Pages: 154555
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Publication
35373908 | J:327512
First Author: Ring J
Year: 2022
Journal: EMBO Mol Med
Title: The HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity.
Volume: 14
Issue: 5
Pages: e13952
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Publication
36280008 | J:331382
 
First Author: Gao WR
Year: 2023
Journal: Behav Brain Res
Title: Selective orexin 1 receptor antagonist SB-334867 aggravated cognitive dysfunction in 3xTg-AD mice.
Volume: 438
Pages: 114171
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Publication
28941799 | J:254181
First Author: Zandl-Lang M
Year: 2018
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Regulatory effects of simvastatin and apoJ on APP processing and amyloid-? clearance in blood-brain barrier endothelial cells.
Volume: 1863
Issue: 1
Pages: 40-60
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Publication
34323038 | J:386654
First Author: Yang P
Year: 2021
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban
Title: [Constructing Brain A??-Targeting Nanoparticles Loaded with EGCG for Treating Alzheimer's Disease in Mice].
Volume: 52
Issue: 4
Pages: 605-611
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Publication
27077851 | J:351765
First Author: Shen L
Year: 2016
Journal: Int J Mol Sci
Title: Redox Proteomic Profiling of Specifically Carbonylated Proteins in the Serum of Triple Transgenic Alzheimer's Disease Mice.
Volume: 17
Issue: 4
Pages: 469
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Publication
28608594 | J:351767
First Author: Nie L
Year: 2017
Journal: Biofactors
Title: Melatonin ameliorates anxiety and depression-like behaviors and modulates proteomic changes in triple transgenic mice of Alzheimer's disease.
Volume: 43
Issue: 4
Pages: 593-611
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Publication
35269588 | J:327470
 
First Author: Mart?nez-Iglesias O
Year: 2022
Journal: Int J Mol Sci
Title: Epigenetic Studies in the Male APP/BIN1/COPS5 Triple-Transgenic Mouse Model of Alzheimer's Disease.
Volume: 23
Issue: 5
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Publication
35151213 | J:351778
 
First Author: He Z
Year: 2022
Journal: Phytomedicine
Title: Esculentoside A alleviates cognitive deficits and amyloid pathology through peroxisome proliferator-activated receptor ?-dependent mechanism in an Alzheimer's disease model.
Volume: 98
Pages: 153956
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Publication
40859930 | J:386669
First Author: Gao JM
Year: 2025
Journal: Adv Sci (Weinh)
Title: A Single-Molecule Pleuripotent Scaffold for Combinational Therapy of Alzheimer's Disease via Intranasal Administration.
Volume: 12
Issue: 43
Pages: e11611
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Publication
40678591 | J:386670
 
First Author: Hu Y
Year: 2025
Journal: J Alzheimers Dis Rep
Title: Identification and experimental validation of Alzheimer's disease hub genes via bioinformatics and machine learning.
Volume: 9
Pages: 25424823251356300
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Publication
41069328 | J:386662
First Author: Tettevi EJ
Year: 2025
Journal: Brain Behav
Title: Antibiotic-Induced Gut Dysbiosis Modulates Alzheimer's Disease-Associated Gene Expression and Protein Aggregation in 3xTg-AD Mice via the Gut-Brain Axis.
Volume: 15
Issue: 10
Pages: e70946
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25344396 | J:355781
First Author: Gstir R
Year: 2014
Journal: RNA
Title: Generation of a neuro-specific microarray reveals novel differentially expressed noncoding RNAs in mouse models for neurodegenerative diseases.
Volume: 20
Issue: 12
Pages: 1929-43
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Publication
20798886 | J:284909
   
First Author: Oh KJ
Year: 2010
Journal: Int J Alzheimers Dis
Title: Staging of Alzheimer's pathology in triple transgenic mice: a light and electron microscopic analysis.
Volume: 2010
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Publication
39801363 | J:386667
First Author: Chevalier C
Year: 2025
Journal: Genes Brain Behav
Title: Fecal Microbiota Transplantation (FMT) From a Human at Low Risk for Alzheimer's Disease Improves Short-Term Recognition Memory and Increases Neuroinflammation in a 3xTg AD Mouse Model.
Volume: 24
Issue: 1
Pages: e70012
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Publication
40717458 | J:390054
First Author: Prabhu SS
Year: 2025
Journal: J Alzheimers Dis
Title: Mid-life exposure to chronic stress accelerates cerebrovascular dysfunction and upregulates oxidative stress in Alzheimer's disease mice.
Volume: 107
Issue: 2
Pages: 653-670
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Publication
37714705 | J:353796
First Author: Chen L
Year: 2023
Journal: J Neurosci
Title: Progressive Excitability Changes in the Medial Entorhinal Cortex in the 3xTg Mouse Model of Alzheimer's Disease Pathology.
Volume: 43
Issue: 44
Pages: 7441-7454
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Publication
36576642 | J:351795
First Author: Ballesteros-?lvarez J
Year: 2023
Journal: Geroscience
Title: Urolithin A reduces amyloid-beta load and improves cognitive deficits uncorrelated with plaque burden in a mouse model of Alzheimer's disease.
Volume: 45
Issue: 2
Pages: 1095-1113
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Publication
20092557 | J:158364
First Author: H?rtig W
Year: 2010
Journal: Eur J Neurosci
Title: In vivo labelling of hippocampal beta-amyloid in triple-transgenic mice with a fluorescent acetylcholinesterase inhibitor released from nanoparticles.
Volume: 31
Issue: 1
Pages: 99-109
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Publication
39179121 | J:353954
 
First Author: Marmolejo-Garza A
Year: 2024
Journal: Neurobiol Dis
Title: Nicotinamide riboside modulates the reactive species interactome, bioenergetic status and proteomic landscape in a brain-region-specific manner.
Volume: 200
Pages: 106645
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Publication
35448465 | J:350534
 
First Author: Guzzardi MA
Year: 2022
Journal: Metabolites
Title: Liver and White/Brown Fat Dystrophy Associates with Gut Microbiota and Metabolomic Alterations in 3xTg Alzheimer's Disease Mouse Model.
Volume: 12
Issue: 4
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Publication
31570577 | J:280407
First Author: Martini AC
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Amyloid-beta impairs TOM1-mediated IL-1R1 signaling.
Volume: 116
Issue: 42
Pages: 21198-21206
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Publication
16156741 | J:101318
First Author: Smith IF
Year: 2005
Journal: J Neurochem
Title: Enhanced caffeine-induced Ca2+ release in the 3xTg-AD mouse model of Alzheimer's disease.
Volume: 94
Issue: 6
Pages: 1711-8
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Publication
35682930 | J:327533
 
First Author: Huang C
Year: 2022
Journal: Int J Mol Sci
Title: Sevoflurane Induces Neurotoxicity in the Animal Model with Alzheimer's Disease Neuropathology via Modulating Glutamate Transporter and Neuronal Apoptosis.
Volume: 23
Issue: 11
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Publication
40475700 | J:388623
First Author: Crouzet C
Year: 2025
Journal: Neurophotonics
Title: Cerebrovascular alterations in a mouse model of late-onset Alzheimer's disease.
Volume: 12
Issue: Suppl 1
Pages: S14614
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Publication
36901549 | J:353981
 
First Author: Vianello C
Year: 2023
Journal: Int J Environ Res Public Health
Title: Increased Expression of Autophagy-Related Genes in Alzheimer's Disease-Type 2 Diabetes Mellitus Comorbidity Models in Cells.
Volume: 20
Issue: 5
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Publication
23486975 | J:196598
First Author: Ghosh S
Year: 2013
Journal: J Neurosci
Title: Sustained interleukin-1? overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model.
Volume: 33
Issue: 11
Pages: 5053-64
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Publication
35599482 | J:350538
First Author: Frame G
Year: 2022
Journal: J Alzheimers Dis
Title: Alterations in Retinal Signaling Across Age and Sex in 3xTg Alzheimer's Disease Mice.
Volume: 88
Issue: 2
Pages: 471-492
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Publication
41634017 | J:382740
 
First Author: Li Y
Year: 2026
Journal: Nat Commun
Title: Gut microbiota-dependent 24-hydroxycholesterol metabolism contributes to capsaicin-induced amelioration of Alzheimer's disease-like pathology in mice.
Volume: 17
Issue: 1
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Publication
39511891 | J:379615
First Author: G?naydin C
Year: 2024
Journal: Mol Ther
Title: AAVrh.10 delivery of novel APOE2-Christchurch variant suppresses amyloid and Tau pathology in Alzheimer's disease mice.
Volume: 32
Issue: 12
Pages: 4303-4318
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Publication
- | J:343012
     
First Author: Edwards GA
Year: 2023
Journal: bioRxiv
Title: TMEM106B coding variant is protective and deletion detrimental in a mouse model of tauopathy
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Publication
38941459 | J:350513
First Author: Li C
Year: 2024
Journal: Sci Adv
Title: TGR5 deficiency in excitatory neurons ameliorates Alzheimer's pathology by regulating APP processing.
Volume: 10
Issue: 26
Pages: eado1855
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Publication
38177673 | J:366419
First Author: Guo R
Year: 2024
Journal: Nat Struct Mol Biol
Title: Reduction of DHHC5-mediated beclin 1 S-palmitoylation underlies autophagy decline in aging.
Volume: 31
Issue: 2
Pages: 232-245
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Publication
39096489 | J:353285
First Author: Zwang TJ
Year: 2024
Journal: Cell Rep
Title: Neurofibrillary tangle-bearing neurons have reduced risk of cell death in mice with Alzheimer's pathology.
Volume: 43
Issue: 8
Pages: 114574
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Publication
36536457 | J:338954
First Author: Kim DW
Year: 2022
Journal: Mol Neurodegener
Title: Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes.
Volume: 17
Issue: 1
Pages: 83
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Publication
30068389 | J:319825
First Author: Maziuk BF
Year: 2018
Journal: Acta Neuropathol Commun
Title: RNA binding proteins co-localize with small tau inclusions in tauopathy.
Volume: 6
Issue: 1
Pages: 71
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Publication
37642942 | J:347913
 
First Author: Ralvenius WT
Year: 2023
Journal: J Exp Med
Title: A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation.
Volume: 220
Issue: 11
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Publication
14642273 | J:104240
First Author: Cruz JC
Year: 2003
Journal: Neuron
Title: Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles.
Volume: 40
Issue: 3
Pages: 471-83
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Publication
41171169 | J:377343
First Author: Schouten M
Year: 2025
Journal: J Appl Physiol (1985)
Title: The muscle protein density associates with radiodensity, strength, damage, unloading, and disease: evidence from humans and mice.
Volume: 139
Issue: 6
Pages: 1505-1516
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25231903 | J:217304
First Author: Tagawa K
Year: 2015
Journal: Hum Mol Genet
Title: Comprehensive phosphoproteome analysis unravels the core signaling network that initiates the earliest synapse pathology in preclinical Alzheimer's disease brain.
Volume: 24
Issue: 2
Pages: 540-58
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Publication
40381614 | J:370100
First Author: Graves SI
Year: 2025
Journal: Neuron
Title: p16-expressing microglia and endothelial cells promote tauopathy and neurovascular abnormalities in PS19 mice.
Volume: 113
Issue: 14
Pages: 2251-2264.e4
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Publication
32557778 | J:311338
First Author: Ferreira S
Year: 2020
Journal: J Neurosci Res
Title: Amyloidosis is associated with thicker myelin and increased oligodendrogenesis in the adult mouse brain.
Volume: 98
Issue: 10
Pages: 1905-1932
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Publication
29346778 | J:324542
First Author: Friedman BA
Year: 2018
Journal: Cell Rep
Title: Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer's Disease Not Evident in Mouse Models.
Volume: 22
Issue: 3
Pages: 832-847
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Publication
40790270 | J:386172
First Author: Pagano Zottola AC
Year: 2025
Journal: Nat Neurosci
Title: Potentiation of mitochondrial function by mitoDREADD-G(s) reverses pharmacological and neurodegenerative cognitive impairment in mice.
Volume: 28
Issue: 9
Pages: 1844-1857
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Publication
39504519 | J:359514
First Author: Welikovitch LA
Year: 2025
Journal: Brain
Title: Tau, synapse loss and gliosis progress in an Alzheimer's mouse model after amyloid-? immunotherapy.
Volume: 148
Issue: 4
Pages: 1316-1328
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Publication
37075107 | J:335302
First Author: Licht-Murava A
Year: 2023
Journal: Sci Adv
Title: Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines.
Volume: 9
Issue: 16
Pages: eade1282
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Publication
33289969 | J:355625
First Author: Morshed N
Year: 2020
Journal: Mol Syst Biol
Title: Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration.
Volume: 16
Issue: 12
Pages: e9819
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Publication
40403715 | J:371883
First Author: Chen K
Year: 2025
Journal: Neuron
Title: Selective removal of astrocytic PERK protects against glymphatic impairment and decreases toxic aggregation of ?-amyloid and tau.
Volume: 113
Issue: 15
Pages: 2438-2454.e6
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Publication
34148071 | J:311242
First Author: Ries M
Year: 2021
Journal: Brain
Title: Annexin A1 restores cerebrovascular integrity concomitant with reduced amyloid-? and tau pathology.
Volume: 144
Issue: 5
Pages: 1526-1541
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Publication
37287063 | J:337840
First Author: Bianchi C
Year: 2023
Journal: Alzheimers Res Ther
Title: P2X7 receptor inhibition ameliorates ubiquitin-proteasome system dysfunction associated with Alzheimer's disease.
Volume: 15
Issue: 1
Pages: 105
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Publication
41188644 | J:375499
First Author: Barnett D
Year: 2025
Journal: Nat Metab
Title: Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology.
Volume: 7
Issue: 11
Pages: 2300-2323
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Strain
MGI:8318865 | B6(Cg)-Psen2<tm1.1(PSEN2)Mdk> Isr(HSA19;APOE_i4)2Mdk Isr(HSA17)1Mdk Psen1<tm1.1(PSEN1)Mdk> App<tm1.1(APP)Mdk>/J
Attribute String: mutant strain, chromosome aberration, targeted mutation
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Strain
MGI:8318878 | B6(Cg)-Psen2<tm2.1(PSEN2*N141I)Mdk> Isr(HSA19;APOE_i4)2Mdk Isr(HSA17;MAPT*N279K)4Mdk Psen1<tm4.1(PSEN1*V272A)Mdk> App<tm1.1(APP)Mdk>/J
Attribute String: mutant strain, chromosome aberration, targeted mutation
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Publication
25815351 | J:335439
First Author: Umeda T
Year: 2015
Journal: Ann Clin Transl Neurol
Title: Passive immunotherapy of tauopathy targeting pSer413-tau: a pilot study in mice.
Volume: 2
Issue: 3
Pages: 241-55
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Genotype
Genotype
Symbol: Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/Tg(APPSwe,tauP301L)1Lfa
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/?
Background: B6.Cg-Psen1 Tg(APPSwe,tauP301L)1Lfa
Zygosity: cx
Has Mutant Allele: true
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Publication
21673655 | J:196042
First Author: Yamagishi S
Year: 2011
Journal: EMBO J
Title: FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons.
Volume: 30
Issue: 14
Pages: 2920-33
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Publication
21835156 | J:176301
First Author: Montgomery SL
Year: 2011
Journal: Am J Pathol
Title: Ablation of TNF-RI/RII expression in Alzheimer's disease mice leads to an unexpected enhancement of pathology: implications for chronic pan-TNF-? suppressive therapeutic strategies in the brain.
Volume: 179
Issue: 4
Pages: 2053-70
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Publication
36170815 | J:329919
First Author: Rangan P
Year: 2022
Journal: Cell Rep
Title: Fasting-mimicking diet cycles reduce neuroinflammation to attenuate cognitive decline in Alzheimer's models.
Volume: 40
Issue: 13
Pages: 111417
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Publication
23147109 | J:203656
 
First Author: Waite MR
Year: 2013
Journal: Mol Cell Neurosci
Title: Pleiotropic and isoform-specific functions for Pitx2 in superior colliculus and hypothalamic neuronal development.
Volume: 52
Pages: 128-39
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Publication
25339759 | J:217151
First Author: Shibuya Y
Year: 2014
Journal: J Neurosci
Title: Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases A?1-42 clearance.
Volume: 34
Issue: 43
Pages: 14484-501
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Publication
20133765 | J:157545
First Author: Bryleva EY
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD.
Volume: 107
Issue: 7
Pages: 3081-6
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Publication
37060096 | J:335721
First Author: Wu D
Year: 2023
Journal: Mol Neurodegener
Title: Targeting a vulnerable septum-hippocampus cholinergic circuit in a critical time window ameliorates tau-impaired memory consolidation.
Volume: 18
Issue: 1
Pages: 23
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Publication
40495777 | J:386720
First Author: Pinedo-Vargas L
Year: 2025
Journal: Hippocampus
Title: Combined Effects of Intermittent Hypoxia and Amyloid Beta on Hippocampal Activity, Its Cholinergic Modulation, and Memory.
Volume: 35
Issue: 4
Pages: e70017
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Publication
40322539 | J:387139
First Author: Cohn W
Year: 2025
Journal: NPJ Drug Discov
Title: Discovery of a small molecule secreted clusterin enhancer that improves memory in Alzheimer's disease mice.
Volume: 2
Issue: 1
Pages: 7
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Publication
32745992 | J:311234
 
First Author: Crapser JD
Year: 2020
Journal: EBioMedicine
Title: Microglia facilitate loss of perineuronal nets in the Alzheimer's disease brain.
Volume: 58
Pages: 102919
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Publication
19664757 | J:281363
First Author: Espa?a J
Year: 2010
Journal: Biol Psychiatry
Title: Intraneuronal beta-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice.
Volume: 67
Issue: 6
Pages: 513-21
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Publication
42015258 | J:387166
 
First Author: Hao JP
Year: 2026
Journal: J Neuroinflammation
Title: Tet2 deficiency orchestrates Alzheimer's pathogenesis through oxidative mtDNA-driven cGAS-STING activation.
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