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Search results 2901 to 3000 out of 3029 for Pdx1

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Type Details Score
Publication
38872370 | J:350483
First Author: Yamaguchi J
Year: 2024
Journal: Cancer Med
Title: Trefoil factor 1 suppresses stemness and enhances chemosensitivity of pancreatic cancer.
Volume: 13
Issue: 11
Pages: e7395
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Publication
26359451 | J:226787
First Author: Dosch JS
Year: 2015
Journal: Cancer Res
Title: Cancer stem cell marker phenotypes are reversible and functionally homogeneous in a preclinical model of pancreatic cancer.
Volume: 75
Issue: 21
Pages: 4582-92
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Publication
35868307 | J:327235
First Author: Chen Y
Year: 2022
Journal: Cancer Cell
Title: Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer.
Volume: 40
Issue: 8
Pages: 818-834.e9
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Publication
30705405 | J:278756
First Author: Nishikawa Y
Year: 2019
Journal: Oncogene
Title: Hes1 plays an essential role in Kras-driven pancreatic tumorigenesis.
Volume: 38
Issue: 22
Pages: 4283-4296
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Publication
38355776 | J:361131
First Author: Astuti Y
Year: 2024
Journal: Nat Cancer
Title: Efferocytosis reprograms the tumor microenvironment to promote pancreatic cancer liver metastasis.
Volume: 5
Issue: 5
Pages: 774-790
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Publication
28414315 | J:241507
First Author: Krebs AM
Year: 2017
Journal: Nat Cell Biol
Title: The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer.
Volume: 19
Issue: 5
Pages: 518-529
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Publication
23958541 | J:324563
First Author: Philip B
Year: 2013
Journal: Gastroenterology
Title: A high-fat diet activates oncogenic Kras and COX2 to induce development of pancreatic ductal adenocarcinoma in mice.
Volume: 145
Issue: 6
Pages: 1449-58
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Publication
31619587 | J:298249
 
First Author: Kim KS
Year: 2019
Journal: JCI Insight
Title: Glycemic effect of pancreatic preproglucagon in mouse sleeve gastrectomy.
Volume: 4
Issue: 20
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Publication
30361701 | J:268101
First Author: Cigliola V
Year: 2018
Journal: Nat Cell Biol
Title: Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon+ α-cells.
Volume: 20
Issue: 11
Pages: 1267-1277
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Publication
27825441 | J:237506
First Author: Houtz J
Year: 2016
Journal: Dev Cell
Title: Neurotrophin Signaling Is Required for Glucose-Induced Insulin Secretion.
Volume: 39
Issue: 3
Pages: 329-345
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Publication
32821827 | J:312564
First Author: Wasylishen AR
Year: 2020
Journal: Sci Adv
Title: Daxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo.
Volume: 6
Issue: 32
Pages: eaba8415
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Publication
26203139 | J:225811
First Author: Kim ER
Year: 2015
Journal: J Neurosci
Title: Hypothalamic Non-AgRP, Non-POMC GABAergic Neurons Are Required for Postweaning Feeding and NPY Hyperphagia.
Volume: 35
Issue: 29
Pages: 10440-50
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Publication
32467243 | J:290417
 
First Author: Lorberbaum DS
Year: 2020
Journal: Development
Title: Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human β cell specification.
Volume: 147
Issue: 12
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hmga2/Hmga2<+> Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53<+>
Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd9/Cd9<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53
Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129X1/SvJ * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd9/Cd9 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53<+>
Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129X1/SvJ * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd9/Cd9 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53
Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129X1/SvJ * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd9/Cd9<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53<+>
Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129X1/SvJ * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Tg(Pdx1-cre)89.1Dam/? Trim29/Trim29 Trp53/Trp53<+>
Background: involves: 129 * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Tg(Pdx1-cre)89.1Dam/? Trim29/Trim29
Background: involves: 129 * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(Pdx1-flpo)#Ybi/?
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac
Zygosity: cn
Has Mutant Allele: true
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Publication
38206362 | J:358305
First Author: Baumel-Alterzon S
Year: 2024
Journal: Diabetologia
Title: NRF2 is required for neonatal mouse beta cell growth by maintaining redox balance and promoting mitochondrial biogenesis and function.
Volume: 67
Issue: 3
Pages: 547-560
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Protein
Q6XP49
Organism: Mus musculus/domesticus
Length: 780  
Fragment?: false
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Protein
A2AWH8
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: false
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Protein
A2AWH7
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: true
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Protein
Q0GE24
Organism: Mus musculus/domesticus
Length: 935  
Fragment?: false
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Protein
A2VDF9
Organism: Mus musculus/domesticus
Length: 802  
Fragment?: true
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Publication
20562852 | J:162641
First Author: Marcheva B
Year: 2010
Journal: Nature
Title: Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes.
Volume: 466
Issue: 7306
Pages: 627-31
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Publication
33285301 | J:300481
 
First Author: Collier JJ
Year: 2020
Journal: Mol Metab
Title: Pancreatic, but not myeloid-cell, expression of interleukin-1alpha is required for maintenance of insulin secretion and whole body glucose homeostasis.
Volume: 44
Pages: 101140
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Publication
38512414 | J:350675
First Author: Yu V
Year: 2024
Journal: Diabetologia
Title: Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity.
Volume: 67
Issue: 6
Pages: 1079-1094
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Publication
24085033 | J:204991
First Author: Pasek RC
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Advancements and challenges in generating accurate animal models of gestational diabetes mellitus.
Volume: 305
Issue: 11
Pages: E1327-38
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Publication
29069604 | J:254840
First Author: Ferreira RMM
Year: 2017
Journal: Cell Rep
Title: Duct- and Acinar-Derived Pancreatic Ductal Adenocarcinomas Show Distinct Tumor Progression and Marker Expression.
Volume: 21
Issue: 4
Pages: 966-978
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Publication
37341148 | J:338218
First Author: Tsuyama T
Year: 2023
Journal: EMBO Rep
Title: Hypoxia causes pancreatic β-cell dysfunction and impairs insulin secretion by activating the transcriptional repressor BHLHE40.
Volume: 24
Issue: 8
Pages: e56227
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Publication
28425994 | J:254425
First Author: Maddocks ODK
Year: 2017
Journal: Nature
Title: Modulating the therapeutic response of tumours to dietary serine and glycine starvation.
Volume: 544
Issue: 7650
Pages: 372-376
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Publication
25774850 | J:228179
First Author: Marquard J
Year: 2015
Journal: Nat Med
Title: Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment.
Volume: 21
Issue: 4
Pages: 363-72
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Publication
27569912 | J:236387
First Author: Daley D
Year: 2016
Journal: Cell
Title: γδ T Cells Support Pancreatic Oncogenesis by Restraining αβ T Cell Activation.
Volume: 166
Issue: 6
Pages: 1485-1499.e15
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Publication
16397221 | J:105031
First Author: Hruban RH
Year: 2006
Journal: Cancer Res
Title: Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations.
Volume: 66
Issue: 1
Pages: 95-106
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Publication
28049824 | J:239540
First Author: Zhang G
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: p53 pathway is involved in cell competition during mouse embryogenesis.
Volume: 114
Issue: 3
Pages: 498-503
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Publication
29153842 | J:252273
First Author: Todoric J
Year: 2017
Journal: Cancer Cell
Title: Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.
Volume: 32
Issue: 6
Pages: 824-839.e8
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Publication
33393460 | J:308021
   
First Author: Maruno T
Year: 2021
Journal: Elife
Title: Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging.
Volume: 10
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Publication
30842658 | J:274344
First Author: Lee JW
Year: 2019
Journal: Nature
Title: Hepatocytes direct the formation of a pro-metastatic niche in the liver.
Volume: 567
Issue: 7747
Pages: 249-252
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Publication
29808009 | J:336458
First Author: Ruess DA
Year: 2018
Journal: Nat Med
Title: Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase.
Volume: 24
Issue: 7
Pages: 954-960
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Publication
30952657 | J:276349
First Author: Poulin EJ
Year: 2019
Journal: Cancer Discov
Title: Tissue-Specific Oncogenic Activity of KRASA146T.
Volume: 9
Issue: 6
Pages: 738-755
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Publication
31048544 | J:289183
First Author: Wang L
Year: 2019
Journal: Genes Dev
Title: ATDC is required for the initiation of KRAS-induced pancreatic tumorigenesis.
Volume: 33
Issue: 11-12
Pages: 641-655
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Publication
38733589 | J:348743
First Author: Tomić G
Year: 2024
Journal: Cell Rep
Title: Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis.
Volume: 43
Issue: 5
Pages: 114224
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Publication
32541668 | J:291708
First Author: Perkail S
Year: 2020
Journal: Nat Commun
Title: BAP1 is a haploinsufficient tumor suppressor linking chronic pancreatitis to pancreatic cancer in mice.
Volume: 11
Issue: 1
Pages: 3018
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Publication
23467612 | J:197052
First Author: Lin WC
Year: 2013
Journal: Cancer Res
Title: Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer.
Volume: 73
Issue: 6
Pages: 1821-30
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Publication
21205788 | J:169830
First Author: Kopinke D
Year: 2011
Journal: Development
Title: Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas.
Volume: 138
Issue: 3
Pages: 431-41
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Publication
20071774 | J:156681
First Author: Morris JP 4th
Year: 2010
Journal: J Clin Invest
Title: Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice.
Volume: 120
Issue: 2
Pages: 508-20
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Publication
19939939 | J:166881
First Author: Kim I
Year: 2009
Journal: J Am Soc Nephrol
Title: Conditional mutation of Pkd2 causes cystogenesis and upregulates beta-catenin.
Volume: 20
Issue: 12
Pages: 2556-69
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Publication
25939753 | J:222769
First Author: Bednar F
Year: 2015
Journal: Carcinogenesis
Title: Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism.
Volume: 36
Issue: 7
Pages: 730-8
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Publication
36351945 | J:331101
First Author: Sodir NM
Year: 2022
Journal: Nat Commun
Title: Reversible Myc hypomorphism identifies a key Myc-dependency in early cancer evolution.
Volume: 13
Issue: 1
Pages: 6782
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Publication
30996350 | J:280283
First Author: Shi Y
Year: 2019
Journal: Nature
Title: Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring.
Volume: 569
Issue: 7754
Pages: 131-135
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Publication
28031255 | J:240629
First Author: Rath N
Year: 2017
Journal: EMBO Mol Med
Title: ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth.
Volume: 9
Issue: 2
Pages: 198-218
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Publication
29844119 | J:265549
First Author: Cheung PF
Year: 2018
Journal: Cancer Res
Title: Notch-Induced Myeloid Reprogramming in Spontaneous Pancreatic Ductal Adenocarcinoma by Dual Genetic Targeting.
Volume: 78
Issue: 17
Pages: 4997-5010
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Publication
27281208 | J:235743
First Author: Fox RG
Year: 2016
Journal: Nature
Title: Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.
Volume: 534
Issue: 7607
Pages: 407-411
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Publication
37625403 | J:349674
First Author: Mahadevan KK
Year: 2023
Journal: Dev Cell
Title: Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8(+) T cells.
Volume: 58
Issue: 17
Pages: 1562-1577.e8
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Publication
31390573 | J:280212
First Author: Talbert EE
Year: 2019
Journal: Cell Rep
Title: Modeling Human Cancer-induced Cachexia.
Volume: 28
Issue: 6
Pages: 1612-1622.e4
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Publication
28813661 | J:260582
First Author: Zhu Y
Year: 2017
Journal: Immunity
Title: Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression.
Volume: 47
Issue: 2
Pages: 323-338.e6
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Publication
24743474 | J:215194
First Author: Dow LE
Year: 2014
Journal: PLoS One
Title: Conditional reverse tet-transactivator mouse strains for the efficient induction of TRE-regulated transgenes in mice.
Volume: 9
Issue: 4
Pages: e95236
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Publication
24280215 | J:207177
First Author: Zhou Y
Year: 2014
Journal: J Biol Chem
Title: Proteome analysis and conditional deletion of the EAAT2 glutamate transporter provide evidence against a role of EAAT2 in pancreatic insulin secretion in mice.
Volume: 289
Issue: 3
Pages: 1329-44
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Publication
20645310 | J:164697
First Author: Vincent DF
Year: 2010
Journal: Genesis
Title: A rapid strategy to detect the recombined allele in LSL-TβRICA transgenic mice.
Volume: 48
Issue: 9
Pages: 559-62
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Publication
38733583 | J:349756
First Author: Shrestha H
Year: 2024
Journal: Cell Rep
Title: The Janus kinase 1 is critical for pancreatic cancer initiation and progression.
Volume: 43
Issue: 5
Pages: 114202
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Publication
31653840 | J:279957
First Author: Bufe B
Year: 2019
Journal: Nat Commun
Title: Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour.
Volume: 10
Issue: 1
Pages: 4889
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Publication
32154941 | J:288604
First Author: Kalisz M
Year: 2020
Journal: EMBO J
Title: HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer.
Volume: 39
Issue: 9
Pages: e102808
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Publication
21362568 | J:171126
First Author: Smukler SR
Year: 2011
Journal: Cell Stem Cell
Title: The adult mouse and human pancreas contain rare multipotent stem cells that express insulin.
Volume: 8
Issue: 3
Pages: 281-93
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Publication
31509750 | J:281075
First Author: Xue J
Year: 2019
Journal: Cell Rep
Title: CDK8 Regulates Insulin Secretion and Mediates Postnatal and Stress-Induced Expression of Neuropeptides in Pancreatic β Cells.
Volume: 28
Issue: 11
Pages: 2892-2904.e7
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Publication
26123485 | J:222392
First Author: Liu G
Year: 2015
Journal: Hum Mol Genet
Title: Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression.
Volume: 24
Issue: 18
Pages: 5299-312
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Publication
30010625 | J:265678
First Author: Tsuda M
Year: 2018
Journal: J Clin Invest
Title: The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis.
Volume: 128
Issue: 8
Pages: 3475-3489
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Publication
35523176 | J:325642
First Author: Huang H
Year: 2022
Journal: Cancer Cell
Title: Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer.
Volume: 40
Issue: 6
Pages: 656-673.e7
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Publication
31439548 | J:280029
First Author: Mizutani Y
Year: 2019
Journal: Cancer Res
Title: Meflin-Positive Cancer-Associated Fibroblasts Inhibit Pancreatic Carcinogenesis.
Volume: 79
Issue: 20
Pages: 5367-5381
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Publication
30120146 | J:286040
 
First Author: Chen Y
Year: 2018
Journal: EMBO Mol Med
Title: Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program.
Volume: 10
Issue: 10
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Publication
29725089 | J:349143
First Author: Crittenden MR
Year: 2018
Journal: Sci Rep
Title: Tumor cure by radiation therapy and checkpoint inhibitors depends on pre-existing immunity.
Volume: 8
Issue: 1
Pages: 7012
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Publication
35122074 | J:322704
First Author: Falcomatà C
Year: 2022
Journal: Nat Cancer
Title: Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment.
Volume: 3
Issue: 3
Pages: 318-336
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Publication
34385258 | J:321932
First Author: Rovira M
Year: 2021
Journal: Genes Dev
Title: REST is a major negative regulator of endocrine differentiation during pancreas organogenesis.
Volume: 35
Issue: 17-18
Pages: 1229-1242
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Publication
37171959 | J:337581
First Author: Lacombe J
Year: 2023
Journal: Cell Rep
Title: Vitamin K-dependent carboxylation regulates Ca(2+) flux and adaptation to metabolic stress in β cells.
Volume: 42
Issue: 5
Pages: 112500
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Publication
31548432 | J:280398
First Author: Mameishvili E
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer.
Volume: 116
Issue: 41
Pages: 20679-20688
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Publication
36309517 | J:359393
First Author: Dickerson MT
Year: 2022
Journal: Nat Commun
Title: G(i/o) protein-coupled receptor inhibition of beta-cell electrical excitability and insulin secretion depends on Na(+)/K(+) ATPase activation.
Volume: 13
Issue: 1
Pages: 6461
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Protein
Q8BMF4
Organism: Mus musculus/domesticus
Length: 642  
Fragment?: false
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Protein
Q8BKZ9
Organism: Mus musculus/domesticus
Length: 501  
Fragment?: false
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Publication
32304665 | J:290208
First Author: Chung KM
Year: 2020
Journal: Cell
Title: Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma.
Volume: 181
Issue: 4
Pages: 832-847.e18
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Publication
36351408 | J:331107
First Author: Ramakrishnan G
Year: 2022
Journal: Cell Rep
Title: NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma.
Volume: 41
Issue: 6
Pages: 111623
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Publication
27585860 | J:241899
 
First Author: Muzumdar MD
Year: 2016
Journal: Nat Commun
Title: Clonal dynamics following p53 loss of heterozygosity in Kras-driven cancers.
Volume: 7
Pages: 12685
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Publication
37345534 | J:338197
     
First Author: Nakamura T
Year: 2023
Journal: J Pathol
Title: ELF3 suppresses gallbladder cancer development through downregulation of the EREG/EGFR/mTOR complex 1 signalling pathway.
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Publication
27292635 | J:238302
First Author: Byrne KT
Year: 2016
Journal: Cell Rep
Title: CD40 Stimulation Obviates Innate Sensors and Drives T Cell Immunity in Cancer.
Volume: 15
Issue: 12
Pages: 2719-32
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Publication
30926808 | J:273330
First Author: Barilla RM
Year: 2019
Journal: Nat Commun
Title: Specialized dendritic cells induce tumor-promoting IL-10+IL-17+ FoxP3neg regulatory CD4+ T cells in pancreatic carcinoma.
Volume: 10
Issue: 1
Pages: 1424
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Publication
26261055 | J:236511
 
First Author: Yu R
Year: 2016
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