| Type |
Details |
Score |
| Publication |
| First Author: |
Kim Y |
| Year: |
2020 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells. |
| Volume: |
117 |
| Issue: |
16 |
| Pages: |
8900-8911 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Harman CCD |
| Year: |
2021 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
An in vivo screen of noncoding loci reveals that Daedalus is a gatekeeper of an Ikaros-dependent checkpoint during haematopoiesis. |
| Volume: |
118 |
| Issue: |
3 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Christ A |
| Year: |
2010 |
| Journal: |
Kidney Int |
| Title: |
The soluble intracellular domain of megalin does not affect renal proximal tubular function in vivo. |
| Volume: |
78 |
| Issue: |
5 |
| Pages: |
473-7 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
131
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
NS1 is a homodimeric RNA-binding protein found in influenza virus that is required for viral replication. NS1 binds polyA tails of mRNA keeping them in the nucleus. NS1 inhibits pre-mRNA splicing by tightly binding to a specific stem-bulge of U6 snRNA []. |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Heme A synthase catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group [].The type 1 subfamily of this enzyme is found in Gram-positive bacteria. Bacillus subtilis CatA is involved in sporulation []. |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
This domain is found in Legionella ubiquitin-specific protease A (LupA). LupA removes a ubiquitin modification from LegC3 which inactivates the cognate effector. This domain is typical of eukaryotic ubiquitin proteases involved in deconjugation of ubiquitin or ubiquitin-like proteins from their targets []. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ferguson JM |
| Year: |
1978 |
| Journal: |
J Med Genet |
| Title: |
A new type of chondrodystrophic mutant in the mouse. |
| Volume: |
15 |
| Issue: |
2 |
| Pages: |
128-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hara T |
| Year: |
2017 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes. |
| Volume: |
114 |
| Issue: |
22 |
| Pages: |
E4416-E4424 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Michelson AM |
| Year: |
1955 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Dystrophia Muscularis: A HEREDITARY PRIMARY MYOPATHY IN THE HOUSE MOUSE. |
| Volume: |
41 |
| Issue: |
12 |
| Pages: |
1079-84 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ste Marie L |
| Year: |
2000 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A metabolic defect promotes obesity in mice lacking melanocortin-4 receptors. |
| Volume: |
97 |
| Issue: |
22 |
| Pages: |
12339-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hanson RD |
| Year: |
1999 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development. |
| Volume: |
96 |
| Issue: |
25 |
| Pages: |
14372-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tsung A |
| Year: |
2006 |
| Journal: |
Am J Physiol Gastrointest Liver Physiol |
| Title: |
The transcription factor interferon regulatory factor-1 mediates liver damage during ischemia-reperfusion injury. |
| Volume: |
290 |
| Issue: |
6 |
| Pages: |
G1261-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Noailles A |
| Year: |
2019 |
| Journal: |
Front Cell Neurosci |
| Title: |
The Absence of Toll-Like Receptor 4 Mildly Affects the Structure and Function in the Adult Mouse Retina. |
| Volume: |
13 |
|
| Pages: |
59 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Roy A |
| Year: |
2024 |
| Journal: |
Int J Mol Sci |
| Title: |
Integrative Kinase Activity Profiling and Phosphoproteomics of rd10 Mouse Retina during cGMP-Dependent Retinal Degeneration. |
| Volume: |
25 |
| Issue: |
6 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Görlich A |
| Year: |
2011 |
| Journal: |
PLoS One |
| Title: |
N-cofilin can compensate for the loss of ADF in excitatory synapses. |
| Volume: |
6 |
| Issue: |
10 |
| Pages: |
e26789 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Asimakopoulou A |
| Year: |
2014 |
| Journal: |
Biochim Biophys Acta |
| Title: |
Lipocalin-2 (LCN2) regulates PLIN5 expression and intracellular lipid droplet formation in the liver. |
| Volume: |
1842 |
| Issue: |
10 |
| Pages: |
1513-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Esnault C |
| Year: |
2008 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A placenta-specific receptor for the fusogenic, endogenous retrovirus-derived, human syncytin-2. |
| Volume: |
105 |
| Issue: |
45 |
| Pages: |
17532-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Johnson K |
| Year: |
2012 |
| Journal: |
J Immunol |
| Title: |
IL-7 functionally segregates the pro-B cell stage by regulating transcription of recombination mediators across cell cycle. |
| Volume: |
188 |
| Issue: |
12 |
| Pages: |
6084-92 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Morosky S |
| Year: |
2019 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
The neonatal Fc receptor is a pan-echovirus receptor. |
| Volume: |
116 |
| Issue: |
9 |
| Pages: |
3758-3763 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nielsen AL |
| Year: |
2017 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Engineering of a membrane-triggered activity switch in coagulation factor VIIa. |
| Volume: |
114 |
| Issue: |
47 |
| Pages: |
12454-12459 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suzuki N |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Traveling stripes on the skin of a mutant mouse. |
| Volume: |
100 |
| Issue: |
17 |
| Pages: |
9680-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kurowska-Stolarska M |
| Year: |
2011 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis. |
| Volume: |
108 |
| Issue: |
27 |
| Pages: |
11193-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rosenstein RK |
| Year: |
2014 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Signaling pathways activated by a protease allergen in basophils. |
| Volume: |
111 |
| Issue: |
46 |
| Pages: |
E4963-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Caron KM |
| Year: |
2002 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A genetically clamped renin transgene for the induction of hypertension. |
| Volume: |
99 |
| Issue: |
12 |
| Pages: |
8248-52 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Naveh GRS |
| Year: |
2018 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Nonuniformity in ligaments is a structural strategy for optimizing functionality. |
| Volume: |
115 |
| Issue: |
36 |
| Pages: |
9008-9013 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tauriello DV |
| Year: |
2012 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled. |
| Volume: |
109 |
| Issue: |
14 |
| Pages: |
E812-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang Z |
| Year: |
2018 |
| Journal: |
J Immunol |
| Title: |
Differential Roles of LTβR in Endothelial Cell Subsets for Lymph Node Organogenesis and Maturation. |
| Volume: |
201 |
| Issue: |
1 |
| Pages: |
69-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Berger A |
| Year: |
2012 |
| Journal: |
Genes Brain Behav |
| Title: |
Diminished pheromone-induced sexual behavior in neurokinin-1 receptor deficient (TACR1(-/-)) mice. |
| Volume: |
11 |
| Issue: |
5 |
| Pages: |
568-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Patwardhan A |
| Year: |
2017 |
| Journal: |
Nat Commun |
| Title: |
Routing of the RAB6 secretory pathway towards the lysosome related organelle of melanocytes. |
| Volume: |
8 |
|
| Pages: |
15835 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gustavsson N |
| Year: |
2010 |
| Journal: |
PLoS One |
| Title: |
Neuronal calcium sensor synaptotagmin-9 is not involved in the regulation of glucose homeostasis or insulin secretion. |
| Volume: |
5 |
| Issue: |
11 |
| Pages: |
e15414 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tiwari A |
| Year: |
2013 |
| Journal: |
J Cell Sci |
| Title: |
SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic β-cells. |
| Volume: |
126 |
| Issue: |
Pt 9 |
| Pages: |
1962-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Patsouris D |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
Insulin resistance is associated with MCP1-mediated macrophage accumulation in skeletal muscle in mice and humans. |
| Volume: |
9 |
| Issue: |
10 |
| Pages: |
e110653 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Conner JR |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
IRAK1BP1 inhibits inflammation by promoting nuclear translocation of NF-kappaB p50. |
| Volume: |
107 |
| Issue: |
25 |
| Pages: |
11477-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Benson MD |
| Year: |
2005 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Ephrin-B3 is a myelin-based inhibitor of neurite outgrowth. |
| Volume: |
102 |
| Issue: |
30 |
| Pages: |
10694-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Howell GR |
| Year: |
2004 |
| Journal: |
Genet Res |
| Title: |
Identification of a cryptic lethal mutation in the mouse t(w73) haplotype. |
| Volume: |
84 |
| Issue: |
3 |
| Pages: |
153-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Raafat A |
| Year: |
2009 |
| Journal: |
Oncogene |
| Title: |
Rbpj conditional knockout reveals distinct functions of Notch4/Int3 in mammary gland development and tumorigenesis. |
| Volume: |
28 |
| Issue: |
2 |
| Pages: |
219-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bizzoca A |
| Year: |
2003 |
| Journal: |
Development |
| Title: |
Transgenic mice expressing F3/contactin from the TAG-1 promoter exhibit developmentally regulated changes in the differentiation of cerebellar neurons. |
| Volume: |
130 |
| Issue: |
1 |
| Pages: |
29-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang H |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release. |
| Volume: |
107 |
| Issue: |
26 |
| Pages: |
11942-7 |
|
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•
•
•
•
|
| Publication |
| First Author: |
Okuda A |
| Year: |
2017 |
| Journal: |
BMC Neurosci |
| Title: |
Poly(ADP-ribose) polymerase inhibitors activate the p53 signaling pathway in neural stem/progenitor cells. |
| Volume: |
18 |
| Issue: |
1 |
| Pages: |
14 |
|
•
•
•
•
•
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| Publication |
| First Author: |
Rajagopal A |
| Year: |
2016 |
| Journal: |
Mol Genet Metab |
| Title: |
Restoration of the serum level of SERPINF1 does not correct the bone phenotype in Serpinf1 null mice. |
| Volume: |
117 |
| Issue: |
3 |
| Pages: |
378-82 |
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•
•
•
•
•
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| Publication |
| First Author: |
Ma A |
| Year: |
2024 |
| Journal: |
Neuroscience |
| Title: |
SRSF10 regulates migration of neural progenitor cells and granule cells and affects the formation of dentate gyrus during the development of mouse hippocampus. |
| Volume: |
552 |
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| Pages: |
142-151 |
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•
•
•
•
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| Publication |
| First Author: |
Howell VM |
| Year: |
2007 |
| Journal: |
Hum Mol Genet |
| Title: |
Evidence for a direct role of the disease modifier SCNM1 in splicing. |
| Volume: |
16 |
| Issue: |
20 |
| Pages: |
2506-16 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
328
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
330
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
533
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
328
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gershwin ME |
| Year: |
1979 |
| Journal: |
J Immunol |
| Title: |
Studies of congenitally immunologic mutant New Zealand mice. I. Autoimmune features of hereditarily asplenic (Dh/+) NZB mice; reduction of naturally occurring thymocytotoxic antibody and normal suppressor function. |
| Volume: |
122 |
| Issue: |
2 |
| Pages: |
710-7 |
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•
•
•
•
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| Publication |
| First Author: |
Goc A |
| Year: |
2015 |
| Journal: |
Biochim Biophys Acta |
| Title: |
p70 S6-kinase mediates the cooperation between Akt1 and Mek1 pathways in fibroblast-mediated extracellular matrix remodeling. |
| Volume: |
1853 |
| Issue: |
7 |
| Pages: |
1626-35 |
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•
•
•
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| First Author: |
Sokolovska A |
| Year: |
2013 |
| Journal: |
Nat Immunol |
| Title: |
Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function. |
| Volume: |
14 |
| Issue: |
6 |
| Pages: |
543-53 |
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•
•
•
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| Publication |
| First Author: |
Georgiadi A |
| Year: |
2010 |
| Journal: |
Circ Res |
| Title: |
Induction of cardiac Angptl4 by dietary fatty acids is mediated by peroxisome proliferator-activated receptor beta/delta and protects against fatty acid-induced oxidative stress. |
| Volume: |
106 |
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11 |
| Pages: |
1712-21 |
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•
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| First Author: |
Qiu A |
| Year: |
2022 |
| Journal: |
Front Immunol |
| Title: |
FcγRIV is required for IgG2c mediated enhancement of RBC alloimmunization. |
| Volume: |
13 |
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972723 |
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•
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| First Author: |
Takahashi A |
| Year: |
2018 |
| Journal: |
J Biol Chem |
| Title: |
Loss of cyclin-dependent kinase 1 impairs bone formation, but does not affect the bone-anabolic effects of parathyroid hormone. |
| Volume: |
293 |
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50 |
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19387-19399 |
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Ghosh A |
| Year: |
2020 |
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Transl Psychiatry |
| Title: |
Alzheimer's disease-related dysregulation of mRNA translation causes key pathological features with ageing. |
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10 |
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Mukai A |
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2008 |
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J Cell Sci |
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Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis. |
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121 |
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| First Author: |
Da Li |
| Year: |
2020 |
| Journal: |
Nat Commun |
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Hepatic TET3 contributes to type-2 diabetes by inducing the HNF4α fetal isoform. |
| Volume: |
11 |
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1 |
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Miura A |
| Year: |
2013 |
| Journal: |
J Biol Chem |
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Pituitary adenylate cyclase-activating polypeptide type 1 receptor (PAC1) gene is suppressed by transglutaminase 2 activation. |
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288 |
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•
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Jurisicova A |
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Mol Reprod Dev |
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Expression and regulation of genes associated with cell death during murine preimplantation embryo development. |
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Kersemans V |
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PLoS One |
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An efficient and robust MRI-guided radiotherapy planning approach for targeting abdominal organs and tumours in the mouse. |
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12 |
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Nekrep N |
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2008 |
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Development |
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Signals from the neural crest regulate beta-cell mass in the pancreas. |
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12 |
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Dou C |
| Year: |
2018 |
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Gastroenterology |
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P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts. |
| Volume: |
154 |
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8 |
| Pages: |
2209-2221.e14 |
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•
•
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| First Author: |
Premsrirut PK |
| Year: |
2011 |
| Journal: |
Cell |
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A rapid and scalable system for studying gene function in mice using conditional RNA interference. |
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145 |
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1 |
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Janic A |
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2018 |
| Journal: |
Nat Med |
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DNA repair processes are critical mediators of p53-dependent tumor suppression. |
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24 |
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7 |
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•
•
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Boström H |
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2002 |
| Journal: |
Dev Dyn |
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PDGF-A/PDGF alpha-receptor signaling is required for lung growth and the formation of alveoli but not for early lung branching morphogenesis. |
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•
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Soderling SH |
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Proc Natl Acad Sci U S A |
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Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase. |
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•
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Simarro M |
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2007 |
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Proc Natl Acad Sci U S A |
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Fas-activated serine/threonine phosphoprotein (FAST) is a regulator of alternative splicing. |
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104 |
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27 |
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11370-5 |
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•
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Kao HT |
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Proc Natl Acad Sci U S A |
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