Search our database by keyword

Examples

Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 301 to 336 out of 336 for Abcc1

<< First < Previous | Next > Last >>

0.029s

Type

Details

Score

Protein

Q8C7V6

Organism:	Mus musculus/domesticus
Length:	796
Fragment?:	true

•

Protein

O35379

Organism:	Mus musculus/domesticus
Length:	1528
Fragment?:	false

•

Publication

20923933 | J:185403

First Author:	ElAli A
Year:	2010
Journal:	Sci Signal
Title:	Apolipoprotein E controls ATP-binding cassette transporters in the ischemic brain.
Volume:	3
Issue:	142
Pages:	ra72

•

Publication

37914932 | J:360602

First Author:	Terekhanova NV
Year:	2023
Journal:	Nature
Title:	Epigenetic regulation during cancer transitions across 11 tumour types.
Volume:	623
Issue:	7986
Pages:	432-441

•

Publication

22056557 | J:178632

First Author:	F?l?p K
Year:	2011
Journal:	Biochem Biophys Res Commun
Title:	ABCC6 does not transport vitamin K3-glutathione conjugate from the liver: relevance to pathomechanisms of pseudoxanthoma elasticum.
Volume:	415
Issue:	3
Pages:	468-71

•

Publication

38572427 | J:347653

First Author:	Puris E
Year:	2024
Journal:	Front Pharmacol
Title:	Sex-specific changes in protein expression of membrane transporters in the brain cortex of 5xFAD mouse model of Alzheimer's disease.
Volume:	15

Pages:	1365051

•

Publication

23085402 | J:198872

First Author:	Meszaros P
Year:	2013
Journal:	Biochim Biophys Acta
Title:	The function of the ATP-binding cassette (ABC) transporter ABCB1 is not susceptible to actin disruption.
Volume:	1828
Issue:	2
Pages:	340-51

•

Publication

25385827 | J:217407

First Author:	Ihlefeld K
Year:	2015
Journal:	J Lipid Res
Title:	Upregulation of ABC transporters contributes to chemoresistance of sphingosine 1-phosphate lyase-deficient fibroblasts.
Volume:	56
Issue:	1
Pages:	60-9

•

Publication

25274307 | J:217491

First Author:	Muppidi JR
Year:	2014
Journal:	Nature
Title:	Loss of signalling via G?13 in germinal centre B-cell-derived lymphoma.
Volume:	516
Issue:	7530
Pages:	254-8

•

Publication

30842656 | J:274415

First Author:	Lu E
Year:	2019
Journal:	Nature
Title:	S-Geranylgeranyl-L-glutathione is a ligand for human B cell-confinement receptor P2RY8.
Volume:	567
Issue:	7747
Pages:	244-248

•

Publication

9139711 | -

First Author:	Bogdanov YD
Year:	1997
Journal:	J Biol Chem
Title:	Early expression of a novel nucleotide receptor in the neural plate of Xenopus embryos.
Volume:	272
Issue:	19
Pages:	12583-90

•

Publication

15466006 | -

First Author:	Cantagrel V
Year:	2004
Journal:	J Med Genet
Title:	Disruption of a new X linked gene highly expressed in brain in a family with two mentally retarded males.
Volume:	41
Issue:	10
Pages:	736-42

•

Protein Domain

IPR027669 | P2Y8_rcpt

Type:

Family

Description:

This entry represents the P2Y8 receptor. It was originally identified in Xenopus and found to be activated equipotently by all naturally occurring nucleoside triphosphates (ATP, CTP, GTP, ITP and UTP) but not by inorganic polyphosphates [].P2RY8 is a G protein-coupled receptor for S-geranylgeranyl-glutathione (GGG), an endogenous metabolite present in lymphoid tissues. It couples the binding of GGG to the activation of GNA13 and downstream repression of AKT activation in lymphocytes defining their positioning and growth within lymphoid organs [, , ]. In lymphoid follicles, confines B cells and follicular helper T cells in germinal centers (GCs) in response to GGG local gradients established by GGT5 (via GGG catabolism) and ABCC1 (via extracellular transport) with lower concentrations of GGG found in the follicular dendritic cell network region around which germinal centers are formed [, , ]. In the bone marrow, also in response to GGG gradients established by GGT5 and ABCC1, it restricts chemotactic transmigration of B cells, T cells and NK cells from blood vessels to the bone marrow parenchyma [, ].There are three distinct families of extracellular receptors for purine and pyrimidine nucleotides [], known as P1, P2X and P2Y purinoceptors []. These receptors induce a wide variety of biological effects and are involved in many different cellular functions [, , ]. P2X receptors are ligand-gated ion channels, whereas P1 and P2Y receptors are rhodopsin-like G protein-coupled receptors [, ]. The families also differ by their method of activation: P1 receptors are preferentially activated by adenosine [], P2X via ATP [], whereas the P2Y receptors, in addition to being activated by ATP, are activated by different adenine and/or uridine nucleoside di- and triphosphates (ADP, UDP, UTP, UDP and UDP-glucose) [].The P2Y purinoceptors currently consist of eleven subtypes: P2Y1, P2Y2, P2Y3 P2Y4, P2Y6, P2Y8, P2Y10, P2Y11, P2Y12, P2Y13 and P2Y14 [, , ]. P2Y3 has, as yet, only been found in birds [], whilst the rest have been cloned in humans. The gaps in P2Y receptor numbering are due to the reclassification of some receptors that were initially associated with to the P2Y family. These include P2Y5 (now known as lysophosphatidic acid receptor 6), P2Y7 (now leukotriene B4 receptor) and P2Y9 (lysophosphatidic acid receptor 4) [, , , ].

•

Publication

8872457 | -

First Author:	Van Rhee AM
Year:	1995
Journal:	Drug Des Discov
Title:	Modelling the P2Y purinoceptor using rhodopsin as template.
Volume:	13
Issue:	2
Pages:	133-54

•

Publication

11111826 | -

First Author:	von K?gelgen I
Year:	2000
Journal:	Naunyn Schmiedebergs Arch Pharmacol
Title:	Molecular pharmacology of P2Y-receptors.
Volume:	362
Issue:	4-5
Pages:	310-23

•

Publication

10629443 | -

First Author:	Fern?ndez O
Year:	2000
Journal:	Pharmacology
Title:	Renal vascular reactivity to P(2)-purinoceptor activation in spontaneously hypertensive rats.
Volume:	60
Issue:	1
Pages:	47-50

•

Publication

20471713 | -

First Author:	Marques-da-Silva C
Year:	2011
Journal:	Immunobiology
Title:	Purinergic receptor agonists modulate phagocytosis and clearance of apoptotic cells in macrophages.
Volume:	216
Issue:	1-2
Pages:	1-11

•

Publication

11099464 | -

First Author:	Ferrari D
Year:	2000
Journal:	FASEB J
Title:	The P2 purinergic receptors of human dendritic cells: identification and coupling to cytokine release.
Volume:	14
Issue:	15
Pages:	2466-76

•

Publication

19921464 | -

First Author:	Bulanova E
Year:	2010
Journal:	Purinergic Signal
Title:	P2 receptor-mediated signaling in mast cell biology.
Volume:	6
Issue:	1
Pages:	3-17

•

Publication

11734617 | -

First Author:	Fredholm BB
Year:	2001
Journal:	Pharmacol Rev
Title:	International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors.
Volume:	53
Issue:	4
Pages:	527-52

•

Publication

16257449 | -

First Author:	von K?gelgen I
Year:	2006
Journal:	Pharmacol Ther
Title:	Pharmacological profiles of cloned mammalian P2Y-receptor subtypes.
Volume:	110
Issue:	3
Pages:	415-32

•

Publication

9364468 | -

First Author:	Burnstock G
Year:	1997
Journal:	Neuropharmacology
Title:	The past, present and future of purine nucleotides as signalling molecules.
Volume:	36
Issue:	9
Pages:	1127-39

•

Publication

7724657 | -

First Author:	Abbracchio MP
Year:	1994
Journal:	Pharmacol Ther
Title:	Purinoceptors: are there families of P2X and P2Y purinoceptors?
Volume:	64
Issue:	3
Pages:	445-75

•

Publication

16968944 | -

First Author:	Abbracchio MP
Year:	2006
Journal:	Pharmacol Rev
Title:	International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy.
Volume:	58
Issue:	3
Pages:	281-341

•

Publication

8508924 | -

First Author:	Webb TE
Year:	1993
Journal:	FEBS Lett
Title:	Cloning and functional expression of a brain G-protein-coupled ATP receptor.
Volume:	324
Issue:	2
Pages:	219-25

•

Publication

19386608 | -

First Author:	Yanagida K
Year:	2009
Journal:	J Biol Chem
Title:	Identification and characterization of a novel lysophosphatidic acid receptor, p2y5/LPA6.
Volume:	284
Issue:	26
Pages:	17731-41

•

Publication

8921391 | -

First Author:	Owman C
Year:	1996
Journal:	Genomics
Title:	Cloning of cDNA encoding a putative chemoattractant receptor.
Volume:	37
Issue:	2
Pages:	187-94

•

Publication

8702478 | -

First Author:	Akbar GK
Year:	1996
Journal:	J Biol Chem
Title:	Molecular cloning of a novel P2 purinoceptor from human erythroleukemia cells.
Volume:	271
Issue:	31
Pages:	18363-7

•

Publication

12724320 | -

First Author:	Noguchi K
Year:	2003
Journal:	J Biol Chem
Title:	Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family.
Volume:	278
Issue:	28
Pages:	25600-6

•

Publication

18404483 | -

First Author:	Van Kolen K
Year:	2006
Journal:	Purinergic Signal
Title:	Integration of P2Y receptor-activated signal transduction pathways in G protein-dependent signalling networks.
Volume:	2
Issue:	3
Pages:	451-69

•

Publication

9755289 | -

First Author:	Ralevic V
Year:	1998
Journal:	Pharmacol Rev
Title:	Receptors for purines and pyrimidines.
Volume:	50
Issue:	3
Pages:	413-92

•

Publication

11794691 | -

First Author:	Gachet C
Year:	2001
Journal:	Int J Hematol
Title:	Identification, characterization, and inhibition of the platelet ADP receptors.
Volume:	74
Issue:	4
Pages:	375-81

•

Publication

16914897 | -

First Author:	Montiel M
Year:	2006
Journal:	Cell Physiol Biochem
Title:	P2Y receptors activate MAPK/ERK through a pathway involving PI3K/PDK1/PKC-zeta in human vein endothelial cells.
Volume:	18
Issue:	1-3
Pages:	123-34

•

Publication

16934527 | -

First Author:	Wood JD
Year:	2006
Journal:	Curr Opin Pharmacol
Title:	The enteric purinergic P2Y1 receptor.
Volume:	6
Issue:	6
Pages:	564-70

•

Publication

11004484 | -

First Author:	Adrian K
Year:	2000
Journal:	Biochim Biophys Acta
Title:	Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells.
Volume:	1492
Issue:	1
Pages:	127-38

•

Publication

12270951 | -

First Author:	North RA
Year:	2002
Journal:	Physiol Rev
Title:	Molecular physiology of P2X receptors.
Volume:	82
Issue:	4
Pages:	1013-67

•

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/keywordSearchResults.do?searchOffset=300&searchTerm=Abcc1

MouseMine

Search our database by keyword

Examples

Search results 301 to 336 out of 336 for Abcc1

Categories

Hits by Pathway

Hits by Category

Hits by Strain