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Search results 301 to 400 out of 427 for Apbb1

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Type Details Score
Publication
12089154 | J:113984
First Author: Bruni P
Year: 2002
Journal: J Biol Chem
Title: Fe65, a ligand of the Alzheimer's beta-amyloid precursor protein, blocks cell cycle progression by down-regulating thymidylate synthase expression.
Volume: 277
Issue: 38
Pages: 35481-8
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Publication
17383198 | J:123204
First Author: Ikin AF
Year: 2007
Journal: Mol Cell Neurosci
Title: A macromolecular complex involving the amyloid precursor protein (APP) and the cytosolic adapter FE65 is a negative regulator of axon branching.
Volume: 35
Issue: 1
Pages: 57-63
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Publication
17855370 | J:128398
First Author: Wiley JC
Year: 2007
Journal: J Biol Chem
Title: Fe65 stimulates proteolytic liberation of the beta-amyloid precursor protein intracellular domain.
Volume: 282
Issue: 46
Pages: 33313-25
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Publication
18468999 | J:138111
First Author: Nakaya T
Year: 2008
Journal: J Biol Chem
Title: Regulation of FE65 nuclear translocation and function by amyloid beta-protein precursor in osmotically stressed cells.
Volume: 283
Issue: 27
Pages: 19119-31
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Publication
20036665 | J:157658
First Author: Kawai T
Year: 2010
Journal: FEBS Lett
Title: Roles of the intramolecular regions of FE65 in its trans-accumulation and in p53 stabilization in the nuclear matrix of osmotically stressed cells.
Volume: 584
Issue: 4
Pages: 765-9
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Publication
19343227 | J:164771
First Author: Kajiwara Y
Year: 2009
Journal: PLoS One
Title: FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4.
Volume: 4
Issue: 4
Pages: e5071
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Publication
20637285 | J:171318
First Author: Alvira-Botero X
Year: 2010
Journal: Mol Cell Neurosci
Title: Megalin interacts with APP and the intracellular adapter protein FE65 in neurons.
Volume: 45
Issue: 3
Pages: 306-15
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Publication
18278038 | J:145671
First Author: Ma QH
Year: 2008
Journal: Nat Cell Biol
Title: A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis.
Volume: 10
Issue: 3
Pages: 283-94
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Publication
22429478 | J:316812
 
First Author: Dumanis SB
Year: 2012
Journal: Mol Neurodegener
Title: FE65 as a link between VLDLR and APP to regulate their trafficking and processing.
Volume: 7
Pages: 9
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Publication
16716194 | J:116283
First Author: Nakaya T
Year: 2006
Journal: Genes Cells
Title: Role of APP phosphorylation in FE65-dependent gene transactivation mediated by AICD.
Volume: 11
Issue: 6
Pages: 633-45
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Publication
19282473 | J:147140
First Author: Stante M
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks.
Volume: 106
Issue: 13
Pages: 5093-8
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Publication
17130235 | J:118294
First Author: Bao J
Year: 2007
Journal: Mol Cell Biol
Title: Suppression of beta-amyloid precursor protein signaling into the nucleus by estrogens mediated through complex formation between the estrogen receptor and Fe65.
Volume: 27
Issue: 4
Pages: 1321-33
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Publication
26276215 | J:251429
First Author: Lee HJ
Year: 2015
Journal: Biochim Biophys Acta
Title: Fe65 negatively regulates Jagged1 signaling by decreasing Jagged1 protein stability through the E3 ligase Neuralized-like 1.
Volume: 1853
Issue: 11 Pt A
Pages: 2918-28
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Publication
11517249 | J:114052
First Author: Matsuda S
Year: 2001
Journal: J Neurosci
Title: c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK.
Volume: 21
Issue: 17
Pages: 6597-607
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Publication
26258302 | J:225789
First Author: Durst R
Year: 2015
Journal: Nature
Title: Mutations in DCHS1 cause mitral valve prolapse.
Volume: 525
Issue: 7567
Pages: 109-13
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Publication
18723004 | J:145075
 
First Author: Carlson ES
Year: 2008
Journal: Brain Res
Title: Iron deficiency alters expression of genes implicated in Alzheimer disease pathogenesis.
Volume: 1237
Pages: 75-83
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Publication
10945997 | J:113902
First Author: Lambrechts A
Year: 2000
Journal: J Biol Chem
Title: cAMP-dependent protein kinase phosphorylation of EVL, a Mena/VASP relative, regulates its interaction with actin and SH3 domains.
Volume: 275
Issue: 46
Pages: 36143-51
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Publication
9407065 | J:44866
First Author: Ermekova KS
Year: 1997
Journal: J Biol Chem
Title: The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled.
Volume: 272
Issue: 52
Pages: 32869-77
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Publication
15944124 | J:100260
First Author: Pardossi-Piquard R
Year: 2005
Journal: Neuron
Title: Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP.
Volume: 46
Issue: 4
Pages: 541-54
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Publication
16407979 | J:105160
First Author: Guénette S
Year: 2006
Journal: EMBO J
Title: Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development.
Volume: 25
Issue: 2
Pages: 420-31
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Publication
21228158 | J:168231
First Author: Forni PE
Year: 2011
Journal: J Neurosci
Title: A role for FE65 in controlling GnRH-1 neurogenesis.
Volume: 31
Issue: 2
Pages: 480-91
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Publication
16301330 | J:104505
First Author: Muresan Z
Year: 2005
Journal: J Cell Biol
Title: Coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1.
Volume: 171
Issue: 4
Pages: 615-25
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Publication
15529118 | J:94148
 
First Author: Frederikse PH
Year: 2004
Journal: Mol Vis
Title: Synapsin and synaptic vesicle protein expression during embryonic and post-natal lens fiber cell differentiation.
Volume: 10
Pages: 794-804
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Publication
22560297 | J:184521
First Author: Koss M
Year: 2012
Journal: Dev Cell
Title: Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
Volume: 22
Issue: 5
Pages: 913-26
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Publication
9371744 | J:44483
First Author: Brady KP
Year: 1997
Journal: Genome Res
Title: Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.
Volume: 7
Issue: 11
Pages: 1085-93
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Apbb1<em1Smoc> | MGI:7288283
Name: amyloid beta precursor protein binding family B member 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6428172 | C57BL/6JSmoc-Apbb1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Tg(Camk2a-App*,-Apbb1)25Spim | MGI:4366527
Name: transgene insertion 25, Sanjay W Pimplikar
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:4366743 | C57BL/6-Tg(Camk2a-App*,-Apbb1)25Spim
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:4838017 | C57BL/6-Tg(Camk2a-App*,-Apbb1)25Spim/J
Attribute String: coisogenic, mutant strain, transgenic
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Genotype
Genotype
Symbol: Tg(Camk2a-App*,-Apbb1)25Spim/?
Background: C57BL/6-Tg(Camk2a-App*,-Apbb1)25Spim
Zygosity: ot
Has Mutant Allele: true
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Publication
16230462 | J:102815
First Author: Ryan KA
Year: 2005
Journal: J Cell Biol
Title: Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain.
Volume: 171
Issue: 2
Pages: 327-35
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Publication
20493588 | J:188240
First Author: Ghosal K
Year: 2011
Journal: Neurobiol Aging
Title: Aging and excitotoxic stress exacerbate neural circuit reorganization in amyloid precursor protein intracellular domain transgenic mice.
Volume: 32
Issue: 12
Pages: 2320.e1-9
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Publication
19837693 | J:153738
First Author: Ghosal K
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain.
Volume: 106
Issue: 43
Pages: 18367-72
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Publication
27459671 | J:249210
First Author: Ghosal K
Year: 2016
Journal: PLoS One
Title: Tau Protein Mediates APP Intracellular Domain (AICD)-Induced Alzheimer's-Like Pathological Features in Mice.
Volume: 11
Issue: 7
Pages: e0159435
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Publication
19703557 | J:164849
First Author: Jiao J
Year: 2009
Journal: Biochim Biophys Acta
Title: Abnormal regulation of TSG101 in mice with spongiform neurodegeneration.
Volume: 1792
Issue: 10
Pages: 1027-35
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Protein
P70415
Organism: Mus musculus/domesticus
Length: 61  
Fragment?: true
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Protein
E0CYY8
Organism: Mus musculus/domesticus
Length: 93  
Fragment?: true
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Protein
A0A087WRY7
Organism: Mus musculus/domesticus
Length: 145  
Fragment?: true
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Protein
A0A494B8W9
Organism: Mus musculus/domesticus
Length: 57  
Fragment?: true
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Protein
E0CZA9
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: true
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Protein
E0CYJ4
Organism: Mus musculus/domesticus
Length: 107  
Fragment?: true
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Publication
18550529 | -
First Author: Radzimanowski J
Year: 2008
Journal: J Biol Chem
Title: Crystal structure of the human Fe65-PTB1 domain.
Volume: 283
Issue: 34
Pages: 23113-20
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Publication
28323844 | -
First Author: Koistinen NA
Year: 2017
Journal: PLoS One
Title: Nuclear localization of amyloid-β precursor protein-binding protein Fe65 is dependent on regulated intramembrane proteolysis.
Volume: 12
Issue: 3
Pages: e0173888
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Publication
9461550 | -
 
First Author: Duilio A
Year: 1998
Journal: Biochem J
Title: Fe65L2: a new member of the Fe65 protein family interacting with the intracellular domain of the Alzheimer's beta-amyloid precursor protein.
Volume: 330 ( Pt 1)
Pages: 513-9
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Publication
11896189 | -
First Author: Zambrano N
Year: 2002
Journal: J Cell Sci
Title: feh-1 and apl-1, the Caenorhabditis elegans orthologues of mammalian Fe65 and beta-amyloid precursor protein genes, are involved in the same pathway that controls nematode pharyngeal pumping.
Volume: 115
Issue: Pt 7
Pages: 1411-22
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Publication
28553201 | -
 
First Author: Feilen LP
Year: 2017
Journal: Front Mol Neurosci
Title: Fe65-PTB2 Dimerization Mimics Fe65-APP Interaction.
Volume: 10
Pages: 140
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Publication
14527950 | -
First Author: Chang Y
Year: 2003
Journal: J Biol Chem
Title: Generation of the beta-amyloid peptide and the amyloid precursor protein C-terminal fragment gamma are potentiated by FE65L1.
Volume: 278
Issue: 51
Pages: 51100-7
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Publication
22291198 | -
First Author: Pratelli R
Year: 2012
Journal: Plant Physiol
Title: The ubiquitin E3 ligase LOSS OF GDU2 is required for GLUTAMINE DUMPER1-induced amino acid secretion in Arabidopsis.
Volume: 158
Issue: 4
Pages: 1628-42
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Publication
19737927 | -
First Author: Pérez-Oliva AB
Year: 2009
Journal: J Biol Chem
Title: Mahogunin ring finger-1 (MGRN1) E3 ubiquitin ligase inhibits signaling from melanocortin receptor by competition with Galphas.
Volume: 284
Issue: 46
Pages: 31714-25
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Publication
17229889 | -
First Author: Kim BY
Year: 2007
Journal: Mol Biol Cell
Title: Spongiform neurodegeneration-associated E3 ligase Mahogunin ubiquitylates TSG101 and regulates endosomal trafficking.
Volume: 18
Issue: 4
Pages: 1129-42
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Publication
23756845 | -
 
First Author: Chhangani D
Year: 2013
Journal: Sci Rep
Title: Mahogunin ring finger-1 (MGRN1) suppresses chaperone-associated misfolded protein aggregation and toxicity.
Volume: 3
Pages: 1972
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Publication
28902452 | -
First Author: Mukherjee R
Year: 2017
Journal: Traffic
Title: MGRN1-mediated ubiquitination of α-tubulin regulates microtubule dynamics and intracellular transport.
Volume: 18
Issue: 12
Pages: 791-807
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Protein Domain
IPR039576 | APBB1/2/3
Type: Family
Description: This entry represents the FE65 family, whose members include FE65 (APBB1), FE65L1 (APBB2), and FE65L2 (APBB3). They are adaptor proteins that bind the C-terminal region of the amyloid precursor protein (APP) []. APBB1 is a neuronal adaptor protein involved in brain development, Alzheimer disease amyloid precursor protein (APP) signaling, and proteolytic processing of APP [, ]. It contains three protein-protein interaction domains, one WW domain, and two phosphotyrosine-binding domains (PTBs)[]. The C-terminal Fe65-PTB2 binds a large portion of the APP intracellular domain (AICD) including the GYENPTY internalization sequence fingerprint []. This entry also includes an Fe65 homologue from C. elegans, Feh-1. Besides binding to amyloid precursor protein, it is also involved in the same pathway that controls nematode pharyngeal pumping [].
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Publication
19828212 | J:169998
First Author: Vogt DL
Year: 2011
Journal: Neurobiol Aging
Title: Abnormal neuronal networks and seizure susceptibility in mice overexpressing the APP intracellular domain.
Volume: 32
Issue: 9
Pages: 1725-9
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Protein
Q9CSX9
Organism: Mus musculus/domesticus
Length: 159  
Fragment?: true
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Protein Domain
IPR045195 | MGRN1/RNF157_mRING_C3HC5
Type: Domain
Description: This entry represent the C3HC5-type RING-HC finger found in MGRN1/RNF157 and related proteins. It is distinguished from typical C3HC4 RING-HC finger due to the existence of the additional cysteine residue in the middle portion of the RING finger domain.MGRN1 is a cytosolic E3 ubiquitin-protein ligase that inhibits signalling through the G protein-coupled melanocortin receptors-1 (MC1R), -2 (MC2R) and -4 (MC4R) via ubiquitylation-dependent and -independent processes []. It suppresses chaperone-associated misfolded protein aggregation and toxicity []. MGRN1 interacts with cytosolic prion proteins (PrPs) that are linked with neurodegeneration[]. It also interacts with expanded polyglutamine proteins, and suppresses misfolded polyglutamine aggregation and cytotoxicity. Moreover, MGRN1 inhibits melanocortin receptor signaling by competition with Galphas, suggesting a novel pathway for melanocortin signaling from the cell surface to the nucleus []. Furthermore, MGRN1 interacts with and ubiquitylates TSG101, a key component of the endosomal sorting complex required for transport (ESCRT)-I, and regulates endosomal trafficking. A null mutation in the gene encoding MGRN1 causes spongiform neurodegeneration, suggesting a link between dysregulation of endosomal trafficking and spongiform neurodegeneration [, ].RNF157 is a cytoplasmic E3 ubiquitin ligase predominantly expressed in brain. In cultured neurons, it promotes neuronal survival in an E3 ligase-dependent manner. In contrast, it supports growth and maintenance of dendrites independent of its E3 ligase activity. RNF157 interacts with and ubiquitinates the adaptor protein APBB1 (amyloid beta precursor protein-binding, family B, member 1 or Fe65), which regulates neuronal survival, but not dendritic growth downstream of RNF157. The nuclear localization of APBB1 together with its interaction partner RNA-binding protein SART3 (squamous cell carcinoma antigen recognized by T cells 3 or Tip110) is crucial to trigger apoptosis []. Both MGRN1 and RNF157 contain a modified C3HC5-type RING-HC finger, and a functionally uncharacterized region, known as domain associated with RING2 (DAR2), N-terminal to the RING finger.In Arabidopsis, LOG2 is a predicted E3 ubiquitin ligase that interact with GDU1 and is involved in the regulation of amino acid export from plant cells [].
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Protein Domain
IPR045194 | MGRN1/RNF157-like
Type: Family
Description: This entry represents a group of confirmed and predicted E3 ubiquitin ligases, including MGRN1/RNF157 from humans and LOG2/LUL1-4 from Arabidopsis.MGRN1 is a cytosolic E3 ubiquitin-protein ligase that inhibits signalling through the G protein-coupled melanocortin receptors-1 (MC1R), -2 (MC2R) and -4 (MC4R) via ubiquitylation-dependent and -independent processes []. It suppresses chaperone-associated misfolded protein aggregation and toxicity []. MGRN1 interacts with cytosolic prion proteins (PrPs) that are linked with neurodegeneration[]. It also interacts with expanded polyglutamine proteins, and suppresses misfolded polyglutamine aggregation and cytotoxicity. Moreover, MGRN1 inhibits melanocortin receptor signaling by competition with Galphas, suggesting a novel pathway for melanocortin signaling from the cell surface to the nucleus []. Furthermore, MGRN1 interacts with and ubiquitylates TSG101, a key component of the endosomal sorting complex required for transport (ESCRT)-I, and regulates endosomal trafficking. A null mutation in the gene encoding MGRN1 causes spongiform neurodegeneration, suggesting a link between dysregulation of endosomal trafficking and spongiform neurodegeneration [, ].RNF157 is a cytoplasmic E3 ubiquitin ligase predominantly expressed in brain. In cultured neurons, it promotes neuronal survival in an E3 ligase-dependent manner. In contrast, it supports growth and maintenance of dendrites independent of its E3 ligase activity. RNF157 interacts with and ubiquitinates the adaptor protein APBB1 (amyloid beta precursor protein-binding, family B, member 1 or Fe65), which regulates neuronal survival, but not dendritic growth downstream of RNF157. The nuclear localization of APBB1 together with its interaction partner RNA-binding protein SART3 (squamous cell carcinoma antigen recognized by T cells 3 or Tip110) is crucial to trigger apoptosis []. Both MGRN1 and RNF157 contain a modified C3HC5-type RING-HC finger, and a functionally uncharacterized region, known as domain associated with RING2 (DAR2), N-terminal to the RING finger.In Arabidopsis, LOG2 is a predicted E3 ubiquitin ligase that interact with GDU1 and is involved in the regulation of amino acid export from plant cells [].
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Publication
20689579 | J:163067
First Author: Ghosal K
Year: 2010
Journal: PLoS One
Title: APP intracellular domain impairs adult neurogenesis in transgenic mice by inducing neuroinflammation.
Volume: 5
Issue: 7
Pages: e11866
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Protein
Q9D074
Organism: Mus musculus/domesticus
Length: 532  
Fragment?: false
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Protein
Q3TEL6
Organism: Mus musculus/domesticus
Length: 685  
Fragment?: false
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Protein
F7D0T8
Organism: Mus musculus/domesticus
Length: 506  
Fragment?: true
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Protein
Q8CAR4
Organism: Mus musculus/domesticus
Length: 506  
Fragment?: true
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Protein
A2AAN9
Organism: Mus musculus/domesticus
Length: 681  
Fragment?: false
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Protein
A2AAP0
Organism: Mus musculus/domesticus
Length: 659  
Fragment?: false
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Protein
A0A494BAU6
Organism: Mus musculus/domesticus
Length: 123  
Fragment?: false
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Protein
Q3TEP8
Organism: Mus musculus/domesticus
Length: 357  
Fragment?: false
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Protein
A0A087WQ58
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: true
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Protein
Q9R021
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
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Protein
A0A1B0GRP5
Organism: Mus musculus/domesticus
Length: 89  
Fragment?: false
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