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Search results 301 to 400 out of 4449 for Apc

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Type Details Score
Publication
9000559 | J:38422
First Author: Pierre F
Year: 1997
Journal: Cancer Res
Title: Short-chain fructo-oligosaccharides reduce the occurrence of colon tumors and develop gut-associated lymphoid tissue in Min mice.
Volume: 57
Issue: 2
Pages: 225-8
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Publication
7954427 | J:21369
First Author: Luongo C
Year: 1994
Journal: Cancer Res
Title: Loss of Apc+ in intestinal adenomas from Min mice.
Volume: 54
Issue: 22
Pages: 5947-52
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Publication
9865728 | J:51518
First Author: Yang K
Year: 1998
Journal: Cancer Res
Title: Dietary modulation of carcinoma development in a mouse model for human familial adenomatous polyposis.
Volume: 58
Issue: 24
Pages: 5713-7
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Publication
9159163 | J:40923
First Author: Gould KA
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Localized gene action controlling intestinal neoplasia in mice.
Volume: 94
Issue: 11
Pages: 5848-53
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Publication
7490101 | J:28414
First Author: Xia L
Year: 1995
Journal: Genomics
Title: Evidence for a novel exon in the coding region of the adenomatous polyposis coli (APC) gene.
Volume: 28
Issue: 3
Pages: 589-91
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Publication
31434357 | J:280696
 
First Author: Croes L
Year: 2019
Journal: Cancers (Basel)
Title: Determination of the Potential Tumor-Suppressive Effects of Gsdme in a Chemically Induced and in a Genetically Modified Intestinal Cancer Mouse Model.
Volume: 11
Issue: 8
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GO Term
GO:0034741 | APC-tubulin-IQGAP1 complex
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Publication
15650110 | J:95893
First Author: Perreault N
Year: 2005
Journal: Genes Dev
Title: Foxl1 is a mesenchymal Modifier of Min in carcinogenesis of stomach and colon.
Volume: 19
Issue: 3
Pages: 311-5
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Publication
12130785 | J:77896
First Author: Millar CB
Year: 2002
Journal: Science
Title: Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice.
Volume: 297
Issue: 5580
Pages: 403-5
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Publication
20519134 | J:162418
First Author: Potier M
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Altered SK3/KCa2.3-mediated migration in adenomatous polyposis coli (Apc) mutated mouse colon epithelial cells.
Volume: 397
Issue: 1
Pages: 42-7
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Publication
12242442 | J:79058
First Author: Goss KH
Year: 2002
Journal: Science
Title: Enhanced tumor formation in mice heterozygous for Blm mutation.
Volume: 297
Issue: 5589
Pages: 2051-3
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Publication
22469986 | J:193364
First Author: Heijmans J
Year: 2013
Journal: Oncogene
Title: Rage signalling promotes intestinal tumourigenesis.
Volume: 32
Issue: 9
Pages: 1202-6
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Publication
10786662 | J:61731
First Author: Klein IK
Year: 2000
Journal: Cancer Res
Title: Adenoma-specific alterations of protein kinase C isozyme expression in Apc(MIN) mice.
Volume: 60
Issue: 8
Pages: 2077-80
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Publication
10362808 | J:55509
First Author: Bjerknes M
Year: 1999
Journal: Am J Pathol
Title: Colossal crypts bordering colon adenomas in Apc(Min) mice express full-length Apc.
Volume: 154
Issue: 6
Pages: 1831-4
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Publication
11424022 | J:70382
First Author: Newman JV
Year: 2001
Journal: J Infect Dis
Title: Bacterial infection promotes colon tumorigenesis in Apc(Min/+) mice.
Volume: 184
Issue: 2
Pages: 227-30
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Publication
20144789 | J:157067
First Author: Quyn AJ
Year: 2010
Journal: Cell Stem Cell
Title: Spindle orientation bias in gut epithelial stem cell compartments is lost in precancerous tissue.
Volume: 6
Issue: 2
Pages: 175-81
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Publication
7576992 | J:28572
First Author: Moser AR
Year: 1995
Journal: Eur J Cancer
Title: ApcMin: a mouse model for intestinal and mammary tumorigenesis.
Volume: 31A
Issue: 7-8
Pages: 1061-4
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Publication
26274564 | J:226719
   
First Author: Gao C
Year: 2015
Journal: Elife
Title: FAK/PYK2 promotes the Wnt/β-catenin pathway and intestinal tumorigenesis by phosphorylating GSK3β.
Volume: 4
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Publication
15899788 | J:98546
First Author: Erdman SE
Year: 2005
Journal: Cancer Res
Title: CD4+CD25+ regulatory lymphocytes induce regression of intestinal tumors in ApcMin/+ mice.
Volume: 65
Issue: 10
Pages: 3998-4004
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Publication
9706142 | J:50316
First Author: Mahmoud NN
Year: 1998
Journal: Surgery
Title: Aspirin prevents tumors in a murine model of familial adenomatous polyposis.
Volume: 124
Issue: 2
Pages: 225-31
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Publication
23991210 | J:204916
First Author: Poutahidis T
Year: 2013
Journal: PLoS One
Title: Pathogenic intestinal bacteria enhance prostate cancer development via systemic activation of immune cells in mice.
Volume: 8
Issue: 8
Pages: e73933
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Publication
22057237 | J:178629
First Author: March HN
Year: 2011
Journal: Nat Genet
Title: Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis.
Volume: 43
Issue: 12
Pages: 1202-9
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Publication
12447373 | J:80330
First Author: Haigis KM
Year: 2003
Journal: Nat Genet
Title: A Robertsonian translocation suppresses a somatic recombination pathway to loss of heterozygosity.
Volume: 33
Issue: 1
Pages: 33-9
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Publication
9391129 | J:44639
First Author: Merritt AJ
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Polyclonal structure of intestinal adenomas in ApcMin/+ mice with concomitant loss of Apc+ from all tumor lineages.
Volume: 94
Issue: 25
Pages: 13927-31
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Publication
10451698 | J:52560
First Author: van der Houven van Oordt CW
Year: 1999
Journal: Genes Chromosomes Cancer
Title: The genetic background modifies the spontaneous and X-ray-induced tumor spectrum in the Apc1638N mouse model.
Volume: 24
Issue: 3
Pages: 191-8
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Publication
21915313 | J:177765
First Author: Chen Y
Year: 2011
Journal: PLoS One
Title: Adenomatous polyposis coli regulates axon arborization and cytoskeleton organization via its N-terminus.
Volume: 6
Issue: 9
Pages: e24335
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Publication
32037952 | J:349046
First Author: Blomain ES
Year: 2020
Journal: Cancer Biol Ther
Title: APC-β-catenin-TCF signaling silences the intestinal guanylin-GUCY2C tumor suppressor axis.
Volume: 21
Issue: 5
Pages: 441-451
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Publication
7894569 | J:22355
First Author: Whitehead RH
Year: 1994
Journal: Epithelial Cell Biol
Title: Derivation of conditionally immortalized cell lines containing the Min mutation from the normal colonic mucosa and other tissues of an "Immortomouse"/Min hybrid.
Volume: 3
Issue: 3
Pages: 119-25
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Publication
20844082 | J:182818
First Author: Newton IP
Year: 2010
Journal: Mol Biol Cell
Title: Adenomatous polyposis coli and hypoxia-inducible factor-1{alpha} have an antagonistic connection.
Volume: 21
Issue: 21
Pages: 3630-8
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UniProt Feature
UniProt Feature
Begin: 1
Description: APC membrane recruitment protein 1
Type: chain
End: 1132
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UniProt Feature
UniProt Feature
Begin: 1
Description: APC membrane recruitment protein 3
Type: chain
End: 780
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UniProt Feature
UniProt Feature
Begin: 1
Description: Suppressor APC domain-containing protein 1
Type: chain
End: 146
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UniProt Feature
UniProt Feature
Begin: 1
Description: Suppressor APC domain-containing protein 2
Type: chain
End: 391
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UniProt Feature
UniProt Feature
Begin: 1
Description: APC membrane recruitment protein 2
Type: chain
End: 672
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Publication
34074677 | J:357846
First Author: Friedman DJ
Year: 2021
Journal: Cancer Immunol Res
Title: ST8Sia6 Promotes Tumor Growth in Mice by Inhibiting Immune Responses.
Volume: 9
Issue: 8
Pages: 952-966
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Publication
34385712 | J:308663
First Author: Osman A
Year: 2021
Journal: Nat Immunol
Title: TCF-1 controls Treg cell functions that regulate inflammation, CD8+ T cell cytotoxicity and severity of colon cancer.
Volume: 22
Issue: 9
Pages: 1152-1162
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Publication
15480419 | J:94711
First Author: Reed KR
Year: 2004
Journal: Oncogene
Title: PPARdelta status and Apc-mediated tumourigenesis in the mouse intestine.
Volume: 23
Issue: 55
Pages: 8992-6
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Publication
11956084 | J:76201
First Author: Weber GF
Year: 2002
Journal: Cancer Res
Title: Absence of the CD44 gene prevents sarcoma metastasis.
Volume: 62
Issue: 8
Pages: 2281-6
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Publication
15201952 | J:91647
First Author: Hulboy DL
Year: 2004
Journal: Oncol Rep
Title: The influence of matrix metalloproteinase-7 on early mammary tumorigenesis in the multiple intestinal neoplasia mouse.
Volume: 12
Issue: 1
Pages: 13-7
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Publication
27984746 | J:249254
First Author: Sotiriou SK
Year: 2016
Journal: Mol Cell
Title: Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks.
Volume: 64
Issue: 6
Pages: 1127-1134
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Publication
31097220 | J:279693
First Author: Nam TW
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Effect of EI24 expression on the tumorigenesis of ApcMin/+ colorectal cancer mouse model.
Volume: 514
Issue: 4
Pages: 1087-1092
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Publication
25368155 | J:216754
First Author: Leibowitz B
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: BID mediates selective killing of APC-deficient cells in intestinal tumor suppression by nonsteroidal antiinflammatory drugs.
Volume: 111
Issue: 46
Pages: 16520-5
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Publication
29549256 | J:260746
First Author: Raab M
Year: 2018
Journal: Nat Commun
Title: PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells.
Volume: 9
Issue: 1
Pages: 1106
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Publication
32814052 | J:300781
First Author: Liu F
Year: 2020
Journal: Cell Rep
Title: Suppression of Membranous LRP5 Recycling, Wnt/β-Catenin Signaling, and Colon Carcinogenesis by 15-LOX-1 Peroxidation of Linoleic Acid in PI3P.
Volume: 32
Issue: 7
Pages: 108049
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Publication
19092804 | J:144216
First Author: Barker N
Year: 2009
Journal: Nature
Title: Crypt stem cells as the cells-of-origin of intestinal cancer.
Volume: 457
Issue: 7229
Pages: 608-11
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Publication
32698002 | J:323574
First Author: Bruens L
Year: 2020
Journal: Cell Rep
Title: Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine.
Volume: 32
Issue: 3
Pages: 107937
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Publication
24037525 | J:213044
First Author: Greenow KR
Year: 2014
Journal: Oncogene
Title: Wnt-driven intestinal tumourigenesis is suppressed by Chk1 deficiency but enhanced by conditional haploinsufficiency.
Volume: 33
Issue: 31
Pages: 4089-96
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Publication
36669491 | J:333758
First Author: Novellasdemunt L
Year: 2023
Journal: Stem Cell Reports
Title: USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development.
Volume: 18
Issue: 2
Pages: 570-584
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Publication
23665120 | J:198485
First Author: Myant KB
Year: 2013
Journal: Cell Stem Cell
Title: ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation.
Volume: 12
Issue: 6
Pages: 761-73
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Publication
8094372 | J:3803
First Author: Luongo C
Year: 1993
Journal: Genomics
Title: Mapping of multiple intestinal neoplasia (Min) to proximal chromosome 18 of the mouse.
Volume: 15
Issue: 1
Pages: 3-8
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Publication
9554852 | J:47363
First Author: Behrens J
Year: 1998
Journal: Science
Title: Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta.
Volume: 280
Issue: 5363
Pages: 596-9
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Publication
16249175 | J:105716
First Author: Malliri A
Year: 2006
Journal: J Biol Chem
Title: The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development.
Volume: 281
Issue: 1
Pages: 543-8
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Publication
29438366 | J:317021
First Author: Colomer C
Year: 2018
Journal: Br J Cancer
Title: IKKα is required in the intestinal epithelial cells for tumour stemness.
Volume: 118
Issue: 6
Pages: 839-846
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Publication
10851078 | J:62824
First Author: Shoemaker AR
Year: 2000
Journal: Oncogene
Title: Mlh1 deficiency enhances several phenotypes of Apc(Min)/+ mice.
Volume: 19
Issue: 23
Pages: 2774-9
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Publication
28978472 | J:254193
First Author: Agüera-González S
Year: 2017
Journal: Cell Rep
Title: Adenomatous Polyposis Coli Defines Treg Differentiation and Anti-inflammatory Function through Microtubule-Mediated NFAT Localization.
Volume: 21
Issue: 1
Pages: 181-194
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Publication
19651607 | J:151997
First Author: Kawajiri K
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands.
Volume: 106
Issue: 32
Pages: 13481-6
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Publication
18310091 | J:139925
First Author: Bilger A
Year: 2008
Journal: Carcinogenesis
Title: Widespread hyperplasia induced by transgenic TGFalpha in ApcMin mice is associated with only regional effects on tumorigenesis.
Volume: 29
Issue: 9
Pages: 1825-30
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Publication
21589870 | J:172642
First Author: Sung HJ
Year: 2011
Journal: PLoS One
Title: Ambient oxygen promotes tumorigenesis.
Volume: 6
Issue: 5
Pages: e19785
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Publication
19646806 | J:156656
First Author: Otani K
Year: 2010
Journal: Cancer Lett
Title: Adiponectin suppresses tumorigenesis in Apc(Min)(/+) mice.
Volume: 288
Issue: 2
Pages: 177-82
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Publication
18644872 | J:140355
First Author: Phesse TJ
Year: 2008
Journal: Mol Cell Biol
Title: Deficiency of Mbd2 attenuates Wnt signaling.
Volume: 28
Issue: 19
Pages: 6094-103
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Publication
22464327 | J:186084
First Author: Powell AE
Year: 2012
Journal: Cell
Title: The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor.
Volume: 149
Issue: 1
Pages: 146-58
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Publication
29439001 | J:263054
First Author: Balbinot C
Year: 2018
Journal: J Exp Med
Title: The Cdx2 homeobox gene suppresses intestinal tumorigenesis through non-cell-autonomous mechanisms.
Volume: 215
Issue: 3
Pages: 911-926
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Publication
31813825 | J:292822
First Author: Bensard CL
Year: 2020
Journal: Cell Metab
Title: Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier.
Volume: 31
Issue: 2
Pages: 284-300.e7
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Publication
25939752 | J:222770
First Author: Hatano Y
Year: 2015
Journal: Carcinogenesis
Title: Reducing DNA methylation suppresses colon carcinogenesis by inducing tumor cell differentiation.
Volume: 36
Issue: 7
Pages: 719-29
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Publication
26956214 | J:236502
 
First Author: van der Heijden M
Year: 2016
Journal: Nat Commun
Title: Bcl-2 is a critical mediator of intestinal transformation.
Volume: 7
Pages: 10916
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Publication
18719115 | J:138826
First Author: Yoshimizu T
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: The H19 locus acts in vivo as a tumor suppressor.
Volume: 105
Issue: 34
Pages: 12417-22
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Publication
21436051 | J:171211
First Author: Starr TK
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: A Sleeping Beauty transposon-mediated screen identifies murine susceptibility genes for adenomatous polyposis coli (Apc)-dependent intestinal tumorigenesis.
Volume: 108
Issue: 14
Pages: 5765-70
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Publication
10783313 | J:61979
First Author: Mahmoud NN
Year: 2000
Journal: Carcinogenesis
Title: Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis.
Volume: 21
Issue: 5
Pages: 921-7
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Publication
25070752 | J:215988
First Author: Zhang S
Year: 2014
Journal: Cancer Res
Title: TALEN-mediated somatic mutagenesis in murine models of cancer.
Volume: 74
Issue: 18
Pages: 5311-21
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Publication
8862382 | J:36700
First Author: Arenas RB
Year: 1996
Journal: Surgery
Title: Introduction of human adenomatous polyposis coli gene into Min mice via cationic liposomes.
Volume: 120
Issue: 4
Pages: 712-7; discussion 717-8
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Publication
31160382 | J:279037
First Author: Popow O
Year: 2019
Journal: Mol Cancer Res
Title: Identification of Endogenous Adenomatous Polyposis Coli Interaction Partners and β-Catenin-Independent Targets by Proteomics.
Volume: 17
Issue: 9
Pages: 1828-1841
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Publication
16885356 | J:112096
First Author: Shelton DN
Year: 2006
Journal: Cancer Res
Title: Up-regulation of CYP26A1 in adenomatous polyposis coli-deficient vertebrates via a WNT-dependent mechanism: implications for intestinal cell differentiation and colon tumor development.
Volume: 66
Issue: 15
Pages: 7571-7
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Publication
10069468 | J:53701
First Author: Mahmoud NN
Year: 1999
Journal: Carcinogenesis
Title: Administration of an unconjugated bile acid increases duodenal tumors in a murine model of familial adenomatous polyposis.
Volume: 20
Issue: 2
Pages: 299-303
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Publication
11289129 | J:68469
First Author: Weyant MJ
Year: 2001
Journal: Cancer Res
Title: Reciprocal expression of ERalpha and ERbeta is associated with estrogen-mediated modulation of intestinal tumorigenesis.
Volume: 61
Issue: 6
Pages: 2547-51
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Publication
32971322 | J:313944
First Author: Dunbar K
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: Aspirin Rescues Wnt-Driven Stem-like Phenotype in Human Intestinal Organoids and Increases the Wnt Antagonist Dickkopf-1.
Volume: 11
Issue: 2
Pages: 465-489
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Publication
28363996 | J:242141
First Author: Jiang L
Year: 2017
Journal: Cancer Res
Title: miR-34a and miR-34b/c Suppress Intestinal Tumorigenesis.
Volume: 77
Issue: 10
Pages: 2746-2758
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Publication
36817228 | J:354812
First Author: Qu DC
Year: 2023
Journal: J Transl Genet Genom
Title: Epigenetic effects of high-fat diet on intestinal tumorigenesis in C57BL/6J-Apc (Min/+) mice.
Volume: 7
Issue: 1
Pages: 3-16
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Publication
22344573 | J:187862
First Author: Farrall AL
Year: 2012
Journal: Int J Cancer
Title: Wnt and BMP signals control intestinal adenoma cell fates.
Volume: 131
Issue: 10
Pages: 2242-52
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Publication
15668113 | J:95966
First Author: Husøy T
Year: 2005
Journal: Mutat Res
Title: Adenomatous polyposis coli influences micronuclei induction by PhIP and acrylamide in mouse erythrocytes.
Volume: 580
Issue: 1-2
Pages: 111-8
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Publication
18782851 | J:143119
First Author: Segditsas S
Year: 2008
Journal: Hum Mol Genet
Title: Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice.
Volume: 17
Issue: 24
Pages: 3864-75
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Publication
9472698 | J:45638
First Author: Mahmoud NN
Year: 1998
Journal: Carcinogenesis
Title: The sulfide metabolite of sulindac prevents tumors and restores enterocyte apoptosis in a murine model of familial adenomatous polyposis.
Volume: 19
Issue: 1
Pages: 87-91
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Publication
9724789 | J:49809
First Author: Shoemaker AR
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: A resistant genetic background leading to incomplete penetrance of intestinal neoplasia and reduced loss of heterozygosity in ApcMin/+ mice.
Volume: 95
Issue: 18
Pages: 10826-31
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Publication
15502862 | J:94108
First Author: Colnot S
Year: 2004
Journal: Lab Invest
Title: Colorectal cancers in a new mouse model of familial adenomatous polyposis: influence of genetic and environmental modifiers.
Volume: 84
Issue: 12
Pages: 1619-30
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Publication
29212857 | J:257837
First Author: Hankey W
Year: 2018
Journal: Cancer Res
Title: Mutational Mechanisms That Activate Wnt Signaling and Predict Outcomes in Colorectal Cancer Patients.
Volume: 78
Issue: 3
Pages: 617-630
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Publication
15124022 | J:90168
First Author: Iinuma T
Year: 2004
Journal: J Clin Invest
Title: Prevention of gastrointestinal tumors based on adenomatous polyposis coli gene mutation by dendritic cell vaccine.
Volume: 113
Issue: 9
Pages: 1307-17
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Publication
11196148 | J:67060
First Author: Weyant MJ
Year: 2001
Journal: Cancer Res
Title: (+)-Catechin inhibits intestinal tumor formation and suppresses focal adhesion kinase activation in the min/+ mouse.
Volume: 61
Issue: 1
Pages: 118-25
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Publication
17052257 | J:120998
First Author: Yamada Y
Year: 2007
Journal: Cancer Sci
Title: Multistep carcinogenesis of the colon in Apc(Min/+) mouse.
Volume: 98
Issue: 1
Pages: 6-10
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Publication
20176656 | J:159883
First Author: Robanus-Maandag EC
Year: 2010
Journal: Carcinogenesis
Title: A new conditional Apc-mutant mouse model for colorectal cancer.
Volume: 31
Issue: 5
Pages: 946-52
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Publication
10870964 | J:62965
First Author: Cole AR
Year: 2000
Journal: Electrophoresis
Title: Proteomic analysis of colonic crypts from normal, multiple intestinal neoplasia and p53-null mice: a comparison with colonic polyps.
Volume: 21
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Title: Differential expression of microRNAs in tumors from chronically inflamed or genetic (APC(Min/+)) models of colon cancer.
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Title: Apc(MIN) modulation of vitamin D secosteroid growth control.
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Title: APC-dependent changes in expression of genes influencing polyamine metabolism, and consequences for gastrointestinal carcinogenesis, in the Min mouse.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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